المؤلفون: Deborah Dhuyvetter, Fetene Tekle, Maxim Nazarov, Rob J. Vreeken, Herman Borghys, Frederik Rombouts, Ilse Lenaerts, Astrid Bottelbergs

المصدر: Drug Delivery, Vol 27, Iss 1, Pp 1597-1607 (2020)

مصطلحات موضوعية: drug delivery, nose to brain, intranasal, rat, brain targeting, direct cns transport, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1071-7544Test; https://doaj.org/toc/1521-0464Test

الوصول الحر: https://doaj.org/article/3a2c73fb65e34179bd76465154cdf0e3Test

المؤلفون: Lennart R. S. Huizing (10009412), James McDuffie (10009415), Filip Cuyckens (2331970), Marjolein van Heerden (5818607), Tatiana Koudriakova (1440877), Ron M. A. Heeren (7181636), Rob J. Vreeken (421023)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Physiology, Pharmacology, Biotechnology, Ecology, Cancer, Inorganic Chemistry, Space Science, Chemical Sciences not elsewhere classified, lamina propria, mass spectrometry imaging, luminal concentration, signal, feasibility studies, wall layers, dilution series, gut tissue homogenates, method, tissue type-specific quantitation, Study Drug Distribution, tissue section, tissue distribution data, 7 h, transmural drug distribution, Tissue exposure, lumen, Quantitative Mass Spectrometry Imaging, drug material

العلاقة: https://figshare.com/articles/journal_contribution/Quantitative_Mass_Spectrometry_Imaging_to_Study_Drug_Distribution_in_the_Intestine_Following_Oral_Dosing/13614317Test

الإتاحة: https://doi.org/10.1021/acs.analchem.0c03956.s001Test

المؤلفون: Lieke Lamont, Darya Hadavi, Andrew P. Bowman, Bryn Flinders, Dale Cooper‐Shepherd, Martin Palmer, Jan Jordens, Ynze Mengerink, Maarten Honing, James Langridge, Tiffany Porta Siegel, Rob J. Vreeken, Ron M. A. Heeren

المساهمون: RS: M4I - Imaging Mass Spectrometry (IMS), Imaging Mass Spectrometry (IMS)

المصدر: Rapid Communications in Mass Spectrometry, 37(5):e9439. Wiley

مصطلحات موضوعية: Organic Chemistry, Spectroscopy, Analytical Chemistry

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e451ae0bc9ff8f47267b260fc70b251Test
https://doi.org/10.1002/rcm.9439Test

المؤلفون: null L. Lamont, null D. Hadavi, null A. P. Bowman, null B. Flinders, null D. Cooper‐Shepherd, null M. Palmer, null J. Jordens, null Y. Mengerink, null M. Honing, null J. Langridge, null T. Porta Siegel, null R. J. Vreeken, null R. M. A. Heeren

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4bf44a0707145c95628ab45c893671b2Test
https://doi.org/10.1002/rcm.9439/v2/response1Test

المؤلفون: Carola W.N. Damen, Giorgis Isaac, James Langridge, Thomas Hankemeier, Rob J. Vreeken

المصدر: Journal of Lipid Research, Vol 55, Iss 8, Pp 1772-1783 (2014)

مصطلحات موضوعية: charge surface hybrid column, ultraperformance liquid chromatography, ion-mobility/high-resolution mass spectrometry, structural elucidation, Biochemistry, QD415-436

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S0022227520353402Test; https://doaj.org/toc/0022-2275Test

الوصول الحر: https://doaj.org/article/31683a1a2a814abdb8e01880b42fbeb0Test

المؤلفون: Bryn Flinders, Tiffany Porta Siegel, Darya Hadavi, Brent Viehmann, Rob J. Vreeken, Ron M. A. Heeren, Lieke Lamont

المساهمون: RS: M4I - Imaging Mass Spectrometry (IMS), Imaging Mass Spectrometry (IMS)

المصدر: Analytical and Bioanalytical Chemistry
Analytical and Bioanalytical Chemistry, 413(10), 2779-2791. Springer

مصطلحات موضوعية: Accuracy and precision, MSI comparison, 01 natural sciences, Biochemistry, Mass spectrometry imaging, Mass Spectrometry, Analytical Chemistry, MRM based drug imaging, 03 medical and health sciences, Dogs, Absolute quantification, Pharmacokinetics, Limit of Detection, Animals, Desorption electrospray ionization, 030304 developmental biology, Detection limit, 0303 health sciences, Chromatography, Chemistry, 010401 analytical chemistry, Selected reaction monitoring, 0104 chemical sciences, Triple quadrupole mass spectrometer, Liver, Pharmaceutical Preparations, Mimetic tissue model, Large animal, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee194af7c6a0d7bdf25669bb02920b4Test
https://doi.org/10.1007/s00216-021-03210-0Test

المؤلفون: Herman Borghys, Fetene Tekle, Astrid Bottelbergs, Deborah Dhuyvetter, Rob J. Vreeken, Maxim Nazarov, Ilse Lenaerts, Frederik J. R. Rombouts

المصدر: Drug Delivery
article-version (VoR) Version of Record
Drug Delivery, Vol 27, Iss 1, Pp 1597-1607 (2020)

مصطلحات موضوعية: Male, Chemistry, Pharmaceutical, Pharmaceutical Science, RM1-950, 02 engineering and technology, Pharmacology, 030226 pharmacology & pharmacy, Rats, Sprague-Dawley, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, Drug Delivery Systems, In vivo, brain targeting, Medicine, Animals, rat, Administration, Intranasal, direct CNS transport, business.industry, intranasal, Reproducibility of Results, Biological Transport, General Medicine, Nose to brain, 021001 nanoscience & nanotechnology, Small molecule, Olfactory Bulb, Rats, Brain targeting, Nasal Mucosa, nose to brain, nervous system, Blood-Brain Barrier, Drug delivery, cardiovascular system, Nasal administration, Therapeutics. Pharmacology, 0210 nano-technology, business, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb2691476d9caabc7a0aeebe6957338Test
http://europepmc.org/articles/PMC7655051Test

المؤلفون: Ann Verheyen, Emmie Dumont, Emmanuel Njumbe Ediage, Dirk Van Roosbroeck, Maurice R. Odiere, Lieven J. Stuyver, Ole Lagatie, Alexander Yaw Debrah, Filip Cuyckens, Lieve Dillen, Ruben T'Kindt, Tom Verhaeghe, Koen Sandra, Linda Batsa Debrah, Stijn Van Asten, Rob J. Vreeken

المصدر: PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009999 (2021)
PLoS Neglected Tropical Diseases

مصطلحات موضوعية: Male, Nematoda, Physiology, Metabolite, RC955-962, Glycobiology, Urine, Onchocerciasis, Biochemistry, Mass Spectrometry, Plasma, chemistry.chemical_compound, Medical Conditions, Arctic medicine. Tropical medicine, Medicine and Health Sciences, Metabolites, Biomarker discovery, Lymphatic filariasis, education.field_of_study, biology, Eukaryota, Nucleosides, Lipids, Glycosylamines, Body Fluids, Infectious Diseases, Helminth Infections, Biomarker (medicine), Female, Onchocerca, Anatomy, Public aspects of medicine, RA1-1270, Research Article, Neglected Tropical Diseases, Population, Macrofilaricide, Helminths, Parasitic Diseases, medicine, Animals, Metabolomics, Humans, education, business.industry, Organisms, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Tropical Diseases, Lipid Metabolism, biology.organism_classification, medicine.disease, Invertebrates, Onchocerca volvulus, Inosine, Metabolism, chemistry, Immunology, business, Zoology, Biomarkers, Chromatography, Liquid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87798bbc7354ccb5f9801ef06ea619f5Test
https://doaj.org/article/030bb70bb947461081dd250c0cec2dd8Test

المؤلفون: Maaike J. Bruins, Adrie D. Dane, Katrin Strassburg, Rob J. Vreeken, John W. Newman, Norman Salem, Jr., Cynthia Tyburczy, J.Thomas Brenna

المصدر: Journal of Lipid Research, Vol 54, Iss 6, Pp 1598-1607 (2013)

مصطلحات موضوعية: lipidomics, metabolomics, eicosanoid, prostaglandin, omega-3, omega-6 polyunsaturated fatty acid, Biochemistry, QD415-436

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S0022227520357163Test; https://doaj.org/toc/0022-2275Test

الوصول الحر: https://doaj.org/article/82a8e249b8b047f880ab50f88c35f8dbTest

المؤلفون: Michelle Janssens, Jeroen van Smeden, Gert S. Gooris, Wim Bras, Guiseppe Portale, Peter J. Caspers, Rob J. Vreeken, Thomas Hankemeier, Sanja Kezic, Ron Wolterbeek, Adriana P. Lavrijsen, Joke A. Bouwstra

المصدر: Journal of Lipid Research, Vol 53, Iss 12, Pp 2755-2766 (2012)

مصطلحات موضوعية: ceramide composition, lamellar phase, lateral packing, Biochemistry, QD415-436

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S0022227520418103Test; https://doaj.org/toc/0022-2275Test

الوصول الحر: https://doaj.org/article/1caffa124f8d48e1ae9dd10e82171b46Test