المؤلفون: Huttunen, Johanna, Tampio, Janne, Järvinen, Juulia, Montaser, Ahmed B., Markowicz-Piasecka, Magdalena, Huttunen, Kristiina M.

المساهمون: Yorkshire Cancer Research, Research Council of Finland, Uniwersytet Medyczny w Lodzi

المصدر: Chemico-Biological Interactions ; volume 388, page 110833 ; ISSN 0009-2797

مصطلحات موضوعية: Toxicology, General Medicine

الإتاحة: https://doi.org/10.1016/j.cbi.2023.110833Test
https://api.elsevier.com/content/article/PII:S0009279723005008?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0009279723005008?httpAccept=text/plainTest

المؤلفون: Järvinen, Juulia, Montaser, Ahmed B., Adla, Santosh Kumar, Leppänen, Jukka, Lehtonen, Marko, Vellonen, Kati-Sisko, Laitinen, Tuomo, Jalkanen, Aaro, Elmquist, William F., Timonen, Juri, Huttunen, Kristiina M., Rautio, Jarkko

المساهمون: Academy of Finland, Emil Aaltonen Fundation, Orion Research Fundation, The Finnish Pharmaceutical Society

المصدر: European Journal of Pharmaceutical Sciences ; volume 192, page 106637 ; ISSN 0928-0987

مصطلحات موضوعية: Pharmaceutical Science

الإتاحة: https://doi.org/10.1016/j.ejps.2023.106637Test
https://api.elsevier.com/content/article/PII:S0928098723002671?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0928098723002671?httpAccept=text/plainTest

المؤلفون: Auchynnikava, Tatsiana, Äärelä, Antti, Liljenbäck, Heidi, Järvinen, Juulia, Andriana, Putri, Kovacs, Luciana, Rautio, Jarkko, Rajander, Johan, Virta, Pasi, Roivainen, Anne, Li, Xiang-Guo, Airaksinen, Anu J

المصدر: Auchynnikava , T , Äärelä , A , Liljenbäck , H , Järvinen , J , Andriana , P , Kovacs , L , Rautio , J , Rajander , J , Virta , P , Roivainen , A , Li , X-G & Airaksinen , A J 2023 , ' Tetrazine Glycoconjugate for Pretargeted Positron Emission Tomography Imaging of trans-Cyclooctene-Functionalized Molecular Spherical Nucleic Acids ' , ACS Omega , vol. 8 , no. 48 , pp. 45326-45336 . https://doi.org/10.1021/acsomega.3c04041Test

مصطلحات موضوعية: PET imaging

وصف الملف: application/pdf

العلاقة: https://research.abo.fi/en/publications/93a77e76-d0cd-46ad-8e64-1f12cbde1b67Test

الإتاحة: https://doi.org/10.1021/acsomega.3c04041Test
https://research.abo.fi/en/publications/93a77e76-d0cd-46ad-8e64-1f12cbde1b67Test
https://research.abo.fi/ws/files/58845394/auchynnikava-et-al-2023-tetrazine-glycoconjugate-for-pretargeted-positron-emission-tomography-imaging-of-trans.pdfTest
https://urn.fi/URN:NBN:fi-fe202402197695Test

المؤلفون: Matovic, Jelena, Järvinen, Juulia, Sokka, Iris K., Imlimthan, Surachet, Raitanen, Jan-Erik, Montaser, Ahmed, Maaheimo, Hannu, Huttunen, Kristiina M., Peräniemi, Sirpa, Airaksinen, Anu, Sarparanta, Mirkka, Johansson, Mikael, Rautio, Jarkko, Ekholm, Filip

المساهمون: Department of Chemistry, Tracers in Molecular Imaging (TRIM), Helsinki In Vivo Animal Imaging Platform (HAIP), Helsinki Institute of Sustainability Science (HELSUS)

مصطلحات موضوعية: 116 Chemical sciences, 317 Pharmacy

وصف الملف: application/pdf

العلاقة: The authors would like to thank MSc. Helena Bland (University of Helsinki) and laboratory technician Tarja Ihalainen (University of Eastern Finland) for laboratory assistance, Olli Aitio (Glykos Finland Ltd.) and PhD. Juri Timonen (University of Eastern Finland) for fruitful discussions, and Prof. Hélder A. Santos and Alexandra Correia (University of Helsinki) for the kind permission to use their cell culturing facilities and microplate reader in the cytotoxicity assays. CSC—The Finnish IT Center for Science is acknowledged for providing ample computing resources. Financial support from the Cancer foundation in Finland, the Jane and Aatos Erkko Foundation, the Swedish Cultural Foundation, the Ruth and Nils-Erik Stenbäck Foundation, the University of Helsinki research funds, the Academy of Finland (projects: 289179, 319453, 320102, and 308329), the Waldemar von Frenckell foundation, and the Finnish Cultural Foundation is gratefully acknowledged.; Matovic , J , Järvinen , J , Sokka , I K , Imlimthan , S , Raitanen , J-E , Montaser , A , Maaheimo , H , Huttunen , K M , Peräniemi , S , Airaksinen , A , Sarparanta , M , Johansson , M , Rautio , J & Ekholm , F 2021 , ' Exploring the Biochemical Foundations of a Successful GLUT1-Targeting Strategy to BNCT: Chemical Synthesis and In Vitro Evaluation of the Entire Positional Isomer Library of ortho-Carboranylmethyl-Bearing Glucoconjugates ' , Molecular Pharmaceutics , vol. 18 , no. 1 , pp. 285-304 . https://doi.org/10.1021/acs.molpharmaceut.0c00917Test; ORCID: /0000-0002-5943-3105/work/89113867; ORCID: /0000-0002-2956-4366/work/89116138; ORCID: /0000-0002-4461-2215/work/89116176; ORCID: /0000-0002-2818-7570/work/89117028; ORCID: /0000-0003-2520-2146/work/89117937; ORCID: /0000-0002-9793-8235/work/89117993; 85097802070; 6732db4b-5e8a-465b-ac9f-0d05a19334be; http://hdl.handle.net/10138/340053Test; 000606803900023

الإتاحة: http://hdl.handle.net/10138/340053Test

المؤلفون: Matovic, Jelena, Järvinen, Juulia, Sokka, Iris K., Stockmann, Philipp, Kellert, Martin, Imlimthan, Surachet, Sarparanta, Mirkka, Johansson, Mikael P., Hey-Hawkins, Evamarie, Rautio, Jarkko, Ekholm, Filip S.

المساهمون: Department of Chemistry, Tracers in Molecular Imaging (TRIM), Helsinki Institute of Sustainability Science (HELSUS)

مصطلحات موضوعية: NEUTRON-CAPTURE THERAPY, GLUCOSE TRANSPORTERS, P-BORONOPHENYLALANINE, CANCER, DERIVATIVES, HEAD, NECK, GLYCOSIDES, CHEMISTRY, SYSTEM, 116 Chemical sciences

وصف الملف: application/pdf

العلاقة: The authors would like to thank the Jane and Aatos Erkko Foundation, the Academy of Finland (#308329, #341106, #318422, and #320102) , the Chemistry and Molecular Sciences Graduate School, the Finnish Pharmaceutical Society, the Cancer Foundation, the Ruth and Nils-Erik Stenb?ck Foundation, the University of Helsinki Research Funds, Orion Research Foundation, and the DA A D (#57567358) for financial support. The authors are further grateful to CSC - IT Center for Science for providing access to computa- tional resources.; Matovic , J , Järvinen , J , Sokka , I K , Stockmann , P , Kellert , M , Imlimthan , S , Sarparanta , M , Johansson , M P , Hey-Hawkins , E , Rautio , J & Ekholm , F S 2022 , ' Synthesis and In Vitro Evaluation of a Set of 6-Deoxy-6-thio- carboranyl D-Glucoconjugates Shed Light on the Substrate Specificity of the GLUT1 Transporter ' , ACS Omega , vol. 7 , no. 34 , pp. 30376–30388 . https://doi.org/10.1021/acsomega.2c03646Test; ORCID: /0000-0002-2956-4366/work/122642655; ORCID: /0000-0002-4461-2215/work/122642867; ORCID: /0000-0003-2520-2146/work/122646413; ORCID: /0000-0002-9793-8235/work/122646717; 85136705927; a68e0589-9fec-48be-ac41-5381a4992302; http://hdl.handle.net/10138/350550Test; 000843529300001

الإتاحة: http://hdl.handle.net/10138/350550Test

المؤلفون: Bahrami, Katayun, Järvinen, Juulia, Laitinen, Tuomo, Reinisalo, Mika, Honkakoski, Paavo, Poso, Antti, Huttunen, Kristiina M., Rautio, Jarkko

المساهمون: Suomen Farmaseuttinen Yhdistys, Orionin Tutkimuss??ti, Academy of Finland, It?-Suomen Yliopisto

المصدر: Molecular Pharmaceutics ; volume 20, issue 1, page 206-218 ; ISSN 1543-8384 1543-8392

مصطلحات موضوعية: Drug Discovery, Pharmaceutical Science, Molecular Medicine

الإتاحة: https://doi.org/10.1021/acs.molpharmaceut.2c00594Test

المؤلفون: Järvinen, Juulia¹ (AUTHOR), Pulkkinen, Herkko² (AUTHOR), Rautio, Jarkko¹ (AUTHOR), Timonen, Juri M.^1,3 (AUTHOR) juri.timonen@helsinki.fi

المصدر: Pharmaceutics. Dec2023, Vol. 15 Issue 12, p2663. 23p.

مصطلحات موضوعية: *BORON-neutron capture therapy, *BORON, *BORONIC acids, *BORON compounds, *AMINO acids, *BRAIN tumors

المؤلفون: Matovic, Jelena, Järvinen, Juulia, Bland, Helena C., Sokka, Iris K., Imlimthan, Surachet, Ferrando, Ruth Mateu, Huttunen, Kristiina M., Timonen, Juri, Peräniemi, Sirpa, Aitio, Olli, Airaksinen, Anu J., Sarparanta, Mirkka, Johansson, Mikael P., Rautio, Jarkko, Ekholm, Filip S.

المساهمون: Department of Chemistry

مصطلحات موضوعية: boron neutron capture therapy, cancer therapeutics, carbohydrates, glucose transporters, medicinal chemistry, drug delivery, SQUAMOUS-CELL CARCINOMA, NECK-CANCER, CRYSTAL-STRUCTURE, RECURRENT HEAD, FORCE-FIELD, BASIS-SETS, TRANSPORTERS, DERIVATIVES, CONFORMATION, RECOGNITION, 116 Chemical sciences, 317 Pharmacy

وصف الملف: application/pdf

العلاقة: Jussi Karkkainen (University of Eastern Finland), Ronja Ratto (University of Helsinki), and Joonas Waaramaa (University of Helsinki) are acknowledged for laboratory assistance, and He ' lder A. Santos and Alexandra Correia (University of Helsinki) are acknowledged for their contributions to the cytotoxicity studies. CSC-The Finnish IT Center for Science and the Finnish Grid and Cloud Infrastructure (urn:nbn:fi:research-infras-2016072533) are acknowledged for providing the computational resources required for this work. Further, the authors are grateful for financial support from the Jane and Aatos Erkko foundation, the Cancer foundation, the Swedish Cultural foundation, the Ruth and Nils-Erik Stenback foundation, the Finnish Academy of Science and Letters, the University of Helsinki research funds, the Academy of Finland (projects: 308329, 318422, 289179, and 319453), and the Waldemar von Frenckell foundation.; Matovic , J , Järvinen , J , Bland , H C , Sokka , I K , Imlimthan , S , Ferrando , R M , Huttunen , K M , Timonen , J , Peräniemi , S , Aitio , O , Airaksinen , A J , Sarparanta , M , Johansson , M P , Rautio , J & Ekholm , F S 2020 , ' Addressing the Biochemical Foundations of a Glucose-Based "Trojan Horse"-Strategy to Boron Neutron Capture Therapy : From Chemical Synthesis to In Vitro Assessment ' , Molecular Pharmaceutics , vol. 17 , no. 10 , pp. 3885-3899 . https://doi.org/10.1021/acs.molpharmaceut.0c00630Test; ORCID: /0000-0002-5943-3105/work/83434356; ORCID: /0000-0002-2956-4366/work/83435919; ORCID: /0000-0002-4461-2215/work/83435958; ORCID: /0000-0003-2520-2146/work/83437628; ORCID: /0000-0002-9793-8235/work/83437737; 555905dd-7e17-482a-a0f4-3255a5797add; http://hdl.handle.net/10138/321501Test; 000580389300020

الإتاحة: http://hdl.handle.net/10138/321501Test

المؤلفون: Bahrami, Katayun, Järvinen, Juulia, Laitinen, Tuomo, Reinisalo, Mika, Honkakoski, Paavo, Poso, Antti, Huttunen, Kristiina M., Rautio, Jarkko

المصدر: Molecular Pharmaceutics; 1/2/2023, Vol. 20 Issue 1, p206-218, 13p

المؤلفون: Järvinen, Juulia

المساهمون: fi=Vaasan yliopisto|en=University of Vaasa, fi=Laskentatoimen ja rahoituksen yksikkö|en=School of Accounting and Finance

مصطلحات موضوعية: yhteiskuntavastuu, ympäristö, hyvä hallinto, vastuullisuus, sijoitus, kehittyvät markkinat, Master's Degree Programme in Finance, fi=Laskentatoimi ja rahoitus|en=Accounting and Finance

العلاقة: https://osuva.uwasa.fi/handle/10024/13862Test; URN:NBN:fi-fe2022031523670

الإتاحة: https://osuva.uwasa.fi/handle/10024/13862Test