المؤلفون: Arie O. Verkerk, Illés J. Doszpod, Isabella Mengarelli, Tibor Magyar, Alexandra Polyák, Bence Pászti, Igor R. Efimov, Ronald Wilders, István Koncz

المصدر: Biomedicines, Vol 10, Iss 11, p 2987 (2022)

مصطلحات موضوعية: acetylcholine, action potential duration, Purkinje fiber, human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), L-type Ca2+ current, repolarization, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/2227-9059/10/11/2987Test; https://doaj.org/toc/2227-9059Test

الوصول الحر: https://doaj.org/article/9d5e58f3a0cb46638f8f2e10772df109Test

المؤلفون: Arie O. Verkerk, Suzan J. G. Knottnerus, Vincent Portero, Jeannette C. Bleeker, Sacha Ferdinandusse, Kaomei Guan, Lodewijk IJlst, Gepke Visser, Ronald J. A. Wanders, Frits A. Wijburg, Connie R. Bezzina, Isabella Mengarelli, Riekelt H. Houtkooper

المصدر: Frontiers in Pharmacology, Vol 11 (2021)

مصطلحات موضوعية: very long-chain acyl-CoA dehydrogenase, arrhythmia < cardiovascular, acylcarnitines, action potential, human induced pluripotent stem cell derived cardiomyocytes, patients, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fphar.2020.616834/fullTest; https://doaj.org/toc/1663-9812Test

الوصول الحر: https://doaj.org/article/9bf15979cc1e485ca8dbed0f9ba01156Test

المؤلفون: Christiaan C. Veerman, Isabella Mengarelli, Charlotte D. Koopman, Ronald Wilders, Shirley C. van Amersfoorth, Diane Bakker, Rianne Wolswinkel, Mariam Hababa, Teun P. de Boer, Kaomei Guan, James Milnes, Elisabeth M. Lodder, Jeroen Bakkers, Arie O. Verkerk, Connie R. Bezzina

المصدر: Disease Models & Mechanisms, Vol 12, Iss 7 (2019)

مصطلحات موضوعية: Electrophysiology, Mechanisms, Ion channels, Membrane transport, Transgenic models, Treatment, I(KACh), Medicine, Pathology, RB1-214

وصف الملف: electronic resource

العلاقة: http://dmm.biologists.org/content/12/7/dmm037994Test; https://doaj.org/toc/1754-8403Test; https://doaj.org/toc/1754-8411Test

الوصول الحر: https://doaj.org/article/9a0498e951bf479a8ce5b96fc11940dfTest

المؤلفون: Suzan J. G. Knottnerus, Isabella Mengarelli, Rob C. I. Wüst, Antonius Baartscheer, Jeannette C. Bleeker, Ruben Coronel, Sacha Ferdinandusse, Kaomei Guan, Lodewijk IJlst, Wener Li, Xiaojing Luo, Vincent M. Portero, Ying Ulbricht, Gepke Visser, Ronald J. A. Wanders, Frits A. Wijburg, Arie O. Verkerk, Riekelt H. Houtkooper, Connie R. Bezzina

المصدر: International Journal of Molecular Sciences, Vol 21, Iss 7, p 2589 (2020)

مصطلحات موضوعية: VLCADD, arrhythmias, hiPSC, acylcarnitines, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/1422-0067/21/7/2589Test; https://doaj.org/toc/1661-6596Test; https://doaj.org/toc/1422-0067Test

الوصول الحر: https://doaj.org/article/9291905b068a4faa9e19d8a94197632aTest

المؤلفون: Maike Marczenke, Ilaria Piccini, Isabella Mengarelli, Jakob Fell, Albrecht Röpke, Guiscard Seebohm, Arie O. Verkerk, Boris Greber

المصدر: Frontiers in Physiology, Vol 8 (2017)

مصطلحات موضوعية: induced pluripotent stem cells, disease modeling, cardiac differentiation, Kv1.5, atrial fibrillation, Physiology, QP1-981

وصف الملف: electronic resource

العلاقة: http://journal.frontiersin.org/article/10.3389/fphys.2017.00469/fullTest; https://doaj.org/toc/1664-042XTest

الوصول الحر: https://doaj.org/article/a6c531ad6cdc49de92418ae8f227e181Test

المؤلفون: Christiaan C. Veerman, Isabella Mengarelli, Elisabeth M. Lodder, Georgios Kosmidis, Milena Bellin, Miao Zhang, Sven Dittmann, Kaomei Guan, Arthur A. M. Wilde, Eric Schulze‐Bahr, Boris Greber, Connie R. Bezzina, Arie O. Verkerk

المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 7 (2017)

مصطلحات موضوعية: arrhythmia (heart rhythm disorders), sodium channels, stem cell, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2047-9980Test

الوصول الحر: https://doaj.org/article/31b4d470588642f7847c23b8bd417347Test

المؤلفون: Arie O. Verkerk, Christiaan C. Veerman, Jan G. Zegers, Isabella Mengarelli, Connie R. Bezzina, Ronald Wilders

المصدر: International Journal of Molecular Sciences, Vol 18, Iss 9, p 1873 (2017)

مصطلحات موضوعية: induced pluripotent stem cells, differentiation, retinoic acid, cardiomyocytes, electro-physiology, inward rectifier potassium current, perforated patch-clamp, computer simulations, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/1422-0067/18/9/1873Test; https://doaj.org/toc/1422-0067Test

الوصول الحر: https://doaj.org/article/43cb6bd06b5e4361b8d4a4d6668ee6acTest

المؤلفون: Simona Casini, Vincent Portero, Gerard A Marchal, Carol Ann Remme, Joris R. de Groot, Fransisca A. Nariswari, Kaomei Guan, Antoine H.G. Driessen, Marieke W. Veldkamp, Arie O. Verkerk, Makiri Kawasaki, Nicoline W.E. van den Berg, Isabella Mengarelli

المساهمون: Cardiology, ACS - Heart failure & arrhythmias, Graduate School, Cardiothoracic Surgery, ACS - Pulmonary hypertension & thrombosis, Medical Biology, ACS - Amsterdam Cardiovascular Sciences, APH - Methodology

المصدر: Cardiovascular Drugs and Therapy
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy, 33(6), 649-660. Kluwer Academic Publishers

مصطلحات موضوعية: Male, 0301 basic medicine, Action Potentials, SCN10A/Na 1.8, 030204 cardiovascular system & hematology, 0302 clinical medicine, Left atrial, Atrial Fibrillation, Medicine, Myocytes, Cardiac, Pharmacology (medical), health care economics and organizations, Cardiomyocytes, Voltage-Gated Sodium Channel Blockers, Membrane potential, Sodium channel, Cardiac electrophysiology, General Medicine, cardiovascular system, Cardiology, SCN10A/Nav1.8, Action potential duration, Original Article, Rabbits, Electrophysiologic Techniques, Cardiac, Cardiology and Cardiovascular Medicine, medicine.medical_specialty, Cell type, Heart Ventricles, Induced Pluripotent Stem Cells, Cell Line, Sodium current, NAV1.8 Voltage-Gated Sodium Channel, 03 medical and health sciences, Species Specificity, health services administration, Late sodium current, Internal medicine, Animals, Humans, Atrial Appendage, Heart Atria, Pharmacology, hiPSC-CMs, business.industry, Atrial tissue, Kinetics, 030104 developmental biology, NAV1, business, Patch-clamp

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b4ef2ce4fb577a5fa2c0e1f680be0cTest
https://doi.org/10.1007/s10557-019-06925-6Test

المؤلفون: Mischa Klerk, Calum A. MacRae, Marta Pérez-Hernández, Elisabeth M. Lodder, Paul W. Burridge, Christiaan C. Veerman, Isabella Mengarelli, Richard Redon, Vincent Portero, Gerard A Marchal, Carol Ann Remme, Mario Delmar, Franck Potet, Flavien Charpentier, Kaomei Guan, Svitlana Podliesna, Nuo Yu, Carlos G. Vanoye, Alfred Lewis George, David Y. Chiang, Niels Galjart, Simona Casini, Mariam Jouni, Arie O. Verkerk, Eli Rothenberg, Connie R. Bezzina

المساهمون: Cardiology, Graduate School, ACS - Heart failure & arrhythmias, Human Genetics, Medical Biology, APH - Methodology, Cell biology

المصدر: Circ Res
Circulation research, 129(3), 349-365. Lippincott Williams and Wilkins
Circulation Research, 129(3), 349-365. Lippincott Williams & Wilkins

مصطلحات موضوعية: biology, Physiology, Chemistry, cardiac, Sodium channel, Myocardium, Fluorescence recovery after photobleaching, Nav1.5, biology.organism_classification, electrophysiology, zebrafish, Article, Sodium Channels, Cell biology, Microtubule, Cytoplasm, GSK-3, biology.protein, microscopy, Cardiology and Cardiovascular Medicine, Induced pluripotent stem cell, Zebrafish, myocyte, cardiac, myocyte, microtubule

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ec730de2a7e331c928f42d1d495887Test
https://europepmc.org/articles/PMC8298292Test/

المؤلفون: Isabella Mengarelli, Arie O. Verkerk, Francis A. Ortega, Ruben Coronel, David J. Christini, Trine Krogh-Madsen, Edward J. Vigmond, Namit Gaur

المساهمون: Institut de Mathématiques de Bordeaux (IMB), Université Bordeaux Segalen - Bordeaux 2-Université Sciences et Technologies - Bordeaux 1-Université de Bordeaux (UB)-Institut Polytechnique de Bordeaux (Bordeaux INP)-Centre National de la Recherche Scientifique (CNRS), Medical Biology, Amsterdam Cardiovascular Sciences, Cardiology, ACS - Heart failure & arrhythmias

المصدر: Journal of Molecular and Cellular Cardiology
Journal of Molecular and Cellular Cardiology, Elsevier, 2020, 145, pp.122-132. ⟨10.1016/j.yjmcc.2020.04.019⟩
Journal of molecular and cellular cardiology, 145, 122-132. Academic Press Inc.

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Heart Ventricles, [SDV]Life Sciences [q-bio], Guinea Pigs, Induced Pluripotent Stem Cells, Action Potentials, 030204 cardiovascular system & hematology, Arrhythmias, Ventricular tachycardia, Afterdepolarization, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, medicine, Animals, Humans, Repolarization, Computer Simulation, Myocytes, Cardiac, Repolarization reserve, Molecular Biology, Early afterdepolarization, Human induced pluripotent stem cell cardiomyocytes (hiPSC-CM), Torsade de pointes, Ions, Proarrhythmia, business.industry, Arrhythmias, Cardiac, Reentry, medicine.disease, 3. Good health, Quantitative measure, All-or-none repolarization, 030104 developmental biology, Pharmaceutical Preparations, Ventricular fibrillation, Cardiology, Rabbits, Cardiology and Cardiovascular Medicine, business, Biomarkers, Repolarization failure

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c82429aefd2325f3b6c2439d8bee68Test
https://hal.archives-ouvertes.fr/hal-03492208Test