نتائج البحث - "Irs, insulin receptor substrate"

1

Clinical efficacies, underlying mechanisms and molecular targets of Chinese medicines for diabetic nephropathy treatment and management

المؤلفون: Hai-Yong Chen, Yibin Feng, Cheng Zhang, Ning Wang, Sha Li, Guoyi Tang

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2749-2767 (2021)

مصطلحات موضوعية: LOX1, lectin-like oxidized LDL receptor 1, BUN, blood urea nitrogen, TGBM, thickness of glomerular basement membrane, NQO1, NAD(P)H:quinone oxidoreductase 1, STAT, signal transducers and activators of transcription, N/O, not observed, p62, sequestosome 1 protein, p-IRS1, phospho-IRS1, Review, NOX-4, nicotinamide adenine dinucleotide phosphate-oxidase-4, OCP, oxidative carbonyl protein, Traditional Chinese medicine, AGEs, advanced glycation end-products, N/A, not applicable, TRAF5, tumor-necrosis factor receptor-associated factor 5, Health problems, 0302 clinical medicine, ESRD, end-stage renal disease, LDL, low-density lipoprotein, BMP-7, bone morphogenetic protein-7, TGFβR-I/II, TGF-β receptor I/II, Medicine, P70S6K, 70-kDa ribosomal protein S6 kinase, General Pharmacology, Toxicology and Pharmaceutics, SOCS, suppressor of cytokine signaling proteins, HO-1, heme oxygenase-1, 0303 health sciences, TG, triglyceride, BW, body weight, HDL-C, high density lipoprotein-cholesterol, RASI, renin-angiotensin system inhibitor, ATK, protein kinase B, TBARS, thiobarbituric acid-reactive substance, BCL-XL, B-cell lymphoma-extra large, Gαq, Gq protein alpha subunit, GCK, glucokinase, PI3K, phosphatidylinositol 3 kinases, Systematic review, TLR-2/4, toll-like receptor 2/4, IR, insulin receptor, PERK, protein kinase RNA-like eukaryotic initiation factor 2A kinase, 030220 oncology & carcinogenesis, CRP, C-reactive protein, IRS, insulin receptor substrate, AM, mesangial area, JAK, Janus kinase, FBG, fasting blood glucose, ETAR, endothelium A receptor, LDL-C, low density lipoprotein-cholesterol, CD2AP, CD2-associated protein, eIF2α, eukaryotic initiation factor 2α, RM1-950, mTOR, mammalian target of rapamycin, CHOP, C/EBP homologous protein, STZ, streptozotocin, 03 medical and health sciences, ADE, adverse event, PKC, protein kinase C, LC3, microtubule-associated protein light chain 3, ORP150, 150-kDa oxygen-regulated protein, PGE2, prostaglandin E2, IL-1β/6, interleukin 1β/6, Diabetic kidney disease, IGF-1, insulin-like growth factor 1, EP, E-prostanoid receptor, FN, fibronectin, eGFR, estimated GFR, MDA, malondialdehyde, Chinese medicine, MMP-2, matrix metallopeptidase 2, XBP-1, spliced X box-binding protein 1, TGF-β, tumor growth factor β, GRB 10, growth factor receptor-bound protein 10, medicine.disease, Clinical trial, GRP78, glucose-regulated protein 78, UP, urinary protein, IGF-1R, insulin-like growth factor 1 receptor, ACEI, angiotensin-converting enzyme inhibitor, BCL-2, B-cell lymphoma 2, EMT, epithelial-to-mesenchymal transition, MAPK, mitogen-activated protein kinase, MYD88, myeloid differentiation primary response 88, PBG, postprandial blood glucose, RCT, randomized clinical trial, N/R, not reported, COL-I/IV, collagen I/IV, PINK1, PTEN-induced putative kinase 1, UACR, urinary albumin to creatinine ratio, C, control group, Diabetic nephropathy, GPX, glutathione peroxidase, ICAM-1, intercellular adhesion molecule-1, Bioinformatics, VCAM-1, vascular cell adhesion molecule-1, AMPKα, adenosine monophosphate-activated protein kinase α, DM, diabetes mellitus, TFEB, transcription factor EB, TNF-α, tumor necrosis factor α, Molecular target, IKK-β, IκB kinase β, Signaling pathway, GLUT4, glucose transporter type 4, BAX, BCL-2-associated X protein, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, PARP, poly(ADP-Ribose) polymerase, SMURF-2, SMAD ubiquitination regulatory factor 2, AREs, antioxidant response elements, MD, mean difference, SMAD, small mothers against decapentaplegic, MCP-1, monocyte chemotactic protein-1, VEGF, vascular endothelial growth factor, cAMP, cyclic adenosine monophosphate, ARB, angiotensin receptor blocker, PAI-1, plasminogen activator inhibitor-1, SMD, standard mean difference, JNK, c-Jun N-terminal kinase, NRF2, nuclear factor erythroid 2-related factor 2, IκB-α, inhibitory protein α, Herbal medicine, TCM, traditional Chinese medicine, DG, glomerular diameter, GSK-3, glycogen synthase kinase 3, SIRT1, sirtuin 1, D, duration, HbA1c, glycosylated hemoglobin, WMD, weight mean difference, CTGF, connective tissue growth factor, ER, endoplasmic reticulum, DN, diabetic nephropathy, ROS, reactive oxygen species, CCR, creatinine clearance rate, SOD, superoxide dismutase, Diabetes mellitus, PGC-1α, peroxisome proliferator-activated receptor gamma coactivator 1α, ET-1, endothelin-1, UMA, urinary microalbumin, SCr, serum creatinine, IRE-1α, inositol-requiring enzyme-1α, 030304 developmental biology, TII, tubulointerstitial injury index, RAGE, receptors of AGE, business.industry, GFR, glomerular filtration rate, PTEN, phosphatase and tensin homolog, CI, confidence interval, TC, total cholesterol, SD-rat, Sprague–Dawley rat, UAER, urinary albumin excretion rate, DKD, diabetic kidney disease, T, treatment group, Molecular targets, Therapeutics. Pharmacology, α-SMA, α smooth muscle actin, SD, standard deviation, business, DAG, diacylglycerol, GCLC, glutamate-cysteine ligase catalytic subunit, Kidney disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d8ab4193adc39b242fa3c089b4f517Test
https://doi.org/10.1016/j.apsb.2020.12.020Test

2

S-Allylmercaptocysteine improves alcoholic liver disease partly through a direct modulation of insulin receptor signaling

المؤلفون: Pingping Luo, Rui Zhang, Qian Yu, George L. Tipoe, Ming Zheng, Xiaoming Sun, Yingxia Liu, Jia Xiao, Wei Li, Hong Zhang

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 668-679 (2021)

مصطلحات موضوعية: Alcoholic liver disease, INSR, insulin receptor, TCF/LEF, T-cell factor/lymphoid enhancer factor, AST, aspartate aminotransferase, Pharmacology, TSA, thermal shift assay, 0302 clinical medicine, WAT, white adipose tissues, HSL, hormone sensitive lipase, FFA, free fatty acids, MTT, 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl-tetrazolium bromide, General Pharmacology, Toxicology and Pharmaceutics, NF-κB, nuclear factor kappa B, RER, respiratory exchange ratio, 0303 health sciences, LRP6, low-density lipoprotein receptor related protein 6, TNF, tumor necrosis factor, NAS, NAFLD activity score, biology, TG, triglyceride, Chemistry, NIAAA, National Institute on Alcohol Abuse and Alcoholism, Liver cell, CYP2E1, cytochrome P450 2E1, 030220 oncology & carcinogenesis, LDLR, low-density lipoprotein receptor, NRF2, nuclear factor erythroid 2-related factor 2, IRS, insulin receptor substrate, GTT, glucose tolerance test, Original Article, medicine.symptom, Safety, IRTK, insulin receptor tyrosine kinase, GSK3β, glycogen synthase kinase 3 beta, NAFLD, non-alcoholic fatty liver disease, ALD, alcoholic liver disease, SREBP-1c, sterol regulatory element-binding protein 1c, Inflammation, SPR, surface plasmon resonance, AMPK, adenosine 5′-monophosphate (AMP)-activated protein kinase, SAMC, S-allylmercaptocysteine, 03 medical and health sciences, ADIPOQ, adiponectin, Insulin resistance, ORF, open reading frame, PA, palmitate acid, ALT, alanine aminotransferase, medicine, CPT1, carnitine palmitoyltransferase I, IRS-1, GRB14, growth factor receptor-bound protein 14, Protein kinase B, 030304 developmental biology, ATGL, adipose triglyceride lipase, PPARα, peroxisome proliferator-activated receptor alpha, AKT, lcsh:RM1-950, ALDH2, aldehyde dehydrogenase 2, GSK3β, Lipid metabolism, medicine.disease, S-Allylmercaptocysteine, WT, wild-type, IL, interleukin, TC, total cholesterol, Insulin receptor, FDA, U.S. Food and Drug Administration, lcsh:Therapeutics. Pharmacology, biology.protein, NAC, N-acetyl-cysteine, Steatosis, IGF-1, insulin-like growth factors-1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71348640a2921fa24860e2b42b33f51Test
http://europepmc.org/articles/PMC7982498Test

3

The E3 ligase TRAF4 promotes IGF signaling by mediating atypical ubiquitination of IRS-1

المؤلفون: Bert W. O'Malley, Zhao Wang, Ping Yi, Ramesh Singh, Wenjuan Yu

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, IGFR, insulin-like growth factor receptor, IGF, insulin-like growth factor, medicine.medical_treatment, proliferation, PTB, phosphotyrosine binding, Insulin-Like Growth Factor Receptor, Biochemistry, 03 medical and health sciences, Insulin-like growth factor, chemistry.chemical_compound, Insulin receptor substrate, medicine, Humans, Insulin-Like Growth Factor I, Molecular Biology, Protein kinase B, TNF receptor associated factor (TRAF), Insulin-like growth factor 1 receptor, TNF Receptor-Associated Factor 4, 030102 biochemistry & molecular biology, biology, co-IP, coimmunoprecipitation, Akt, insulin receptor substrate 1 (IRS-1), Ubiquitination, Tyrosine phosphorylation, Cell Biology, insulin-like growth factor (IGF), Ubiquitin ligase, Cell biology, protein phosphorylation, 030104 developmental biology, HEK293 Cells, chemistry, biology.protein, IRS, insulin receptor substrate, Insulin Receptor Substrate Proteins, MCF-7 Cells, Signal transduction, Research Article, HA, hemagglutinin, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9f42ab7ea062e1b118be64301e157cTest
http://europepmc.org/articles/PMC8191236Test

4

Heparan sulfate promotes differentiation of white adipocytes to maintain insulin sensitivity and glucose homeostasis

المؤلفون: Masanobu Morita, Yu Yamaguchi, Fumitoshi Irie, Yu Mei, Ai Shimane, Kazuhiko Yanai, Takeo Yoshikawa, Rina Otsuka, Takuro Matsuzawa

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: HFD, high-fat diet, Glucose uptake, Adipocytes, White, White adipose tissue, Bone Morphogenetic Protein 4, Fibroblast growth factor, Biochemistry, HSBP, HS-binding protein, chemistry.chemical_compound, Mice, NIH, National Institutes of Health, PPARγ, peroxisome proliferator–activated receptor gamma, Adipocyte, Lipid droplet, insulin resistance, bone morphogenetic protein, Glucose homeostasis, Homeostasis, TGF-β, transforming growth factor β, DMEM, Dulbecco's modified Eagle's medium, diabetes, Chemistry, ND, normal diet, Cell Differentiation, WAT, white adipose tissue, Heparan sulfate, Cell biology, FGF1, fibroblast growth factor 1, Adipogenesis, Fibroblast Growth Factor 1, heparan sulfate, Signal Transduction, Research Article, LD, lipid droplet, HS, heparan sulfate, adipocyte, adipogenesis, vWAT, visceral WAT, 3T3-L1 Cells, fibroblast growth factor, Animals, Irs, insulin receptor substrate, Molecular Biology, ITT, insulin tolerance test, BMP4, bone morphogenetic protein 4, Fabp4, fatty acid–binding protein 4, Cell Biology, Glucose, Heparitin Sulfate, CRISPR-Cas Systems

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96a1800166fbc18d437ce1e6f65a7f4Test
https://pubmed.ncbi.nlm.nih.gov/34310946Test

5

Resolving the Paradox of Hepatic Insulin Resistance

المؤلفون: Paul M. Titchenell, Dominic Santoleri

المصدر: Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: 0301 basic medicine, Anabolism, medicine.medical_treatment, LIRKO, liver insulin resistant knockout mice, Review, PI3K, phosphoinositide-3-phosphate kinase, 0302 clinical medicine, Gck, glucokinase, PI3K/Akt Signaling Pathway, Insulin, biology, Gastroenterology, De Novo Lipogenesis, IRS, insulin-receptor substrate, Liver, Lipogenesis, 030211 gastroenterology & hepatology, Signal Transduction, medicine.medical_specialty, TAG, triacylglycerol, HGP, hepatic glucose production, Models, Biological, 03 medical and health sciences, Insulin resistance, Hepatic Glucose Production, Internal medicine, FFA, free fatty acid, GSK3, glycogen synthase kinase 3, medicine, Animals, Humans, SCAP, SREBP cleavage-activating protein, SREBP1c, sterol regulatory element binding protein 1c, T2DM, type II diabetes mellitus, GYS2, glycogen synthase, Hepatology, business.industry, Insulin Signaling, Hypertriglyceridemia, VLDL, very-low-density lipoprotein, ChREBP, carbohydrate response element binding protein, Lipid metabolism, Metabolism, Lipid Metabolism, medicine.disease, PTEN, phosphatase and tensin homolog, mTORC, mechanistic target of rapamycin complex, Insulin receptor, Hepatic Insulin Resistance, 030104 developmental biology, Endocrinology, biology.protein, NAFLD, nonalcoholic fatty liver disease, Insulin Resistance, TSC, tuberous sclerosis complex, business, PIP3, phosphatidylinositol (3,4,5)-trisphosphate

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27eb16d2a993c3fec511936ebd4c8ddTest
https://doi.org/10.1016/j.jcmgh.2018.10.016Test

6

Signaling roles of phosphoinositides in the retina

المؤلفون: Raju V. S. Rajala

المصدر: Journal of Lipid Research, Vol 62, Iss, Pp 100041-(2021)
Journal of Lipid Research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad76a0de070275a6dd0bb666e2b0f8cTest
http://www.sciencedirect.com/science/article/pii/S0022227521000213Test

7

mTOR kinase inhibition disrupts neuregulin 1-ERBB3 autocrine signaling and sensitizes NF2-deficient meningioma cellular models to IGF1R inhibition

المؤلفون: Roberta L. Beauchamp, Vijaya Ramesh, Justin T. Jordan, Serkan Erdin, Scott R. Plotkin, James F. Gusella, Luke Witt

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Receptor, ErbB-3, insulin-like growth factor (IGF) receptor 1, DRC, dose–response curve, mTORC1, SGK1, serum-/glucocorticoid-responsive kinase-1, Biochemistry, meningioma, Receptor, IGF Type 1, mTORC1/mTORC2, mTOR complex 1/mTOR complex 2, Cell Movement, PI3K, Phosphoinositide 3-kinase, Meningeal Neoplasms, Akt PKB, FOXO, Forkhead box protein O, ERBB3, tumor suppressor gene, CM, concentrated medium, Benzoxazoles, Neurofibromin 2, biology, Chemistry, Triazines, Receptor, EphA2, TOR Serine-Threonine Kinases, mammalian target of rapamycin (mTOR), APJ, apelin receptor, Autocrine Communication, MR, maximum response, NF2, Neurofibromatosis 2, ERBB, V-ERB-B avian erythroblastic leukemia viral oncogene homolog, Benzamides, IRS, insulin receptor substrate, PDK1, phosphoinositide-dependent kinase-1, RTK, receptor tyrosine kinase, signaling, brain tumor, Research Article, IC50, inhibitory concentration 50%, Signal Transduction, NRG1, neuregulin-1/heregulin, Morpholines, Neuregulin-1, mTOR, mechanistic/mammalian target of rapamycin, Antibodies, Monoclonal, Humanized, WHO, World Health Organization, 03 medical and health sciences, Growth factor receptor, TGFA, transforming growth factor-alpha, Cell Line, Tumor, otorhinolaryngologic diseases, Humans, Autocrine signalling, Molecular Biology, Mechanistic target of rapamycin, PI3K/AKT/mTOR pathway, dual mTORC1/mTORC2 inhibition, Insulin-like growth factor 1 receptor, Cell Proliferation, Sirolimus, Phosphoinositide 3-kinase, 030102 biochemistry & molecular biology, qPCR, quantitative RT-PCR, Dose-Response Relationship, Drug, EPH receptor, erythropoietin-producing hepatocellular receptor, Lapatinib, Cell Biology, EGFR, epidermal growth factor receptor, AC, arachnoid cell, 030104 developmental biology, Pyrimidines, Gene Expression Regulation, NF2, Cancer research, biology.protein, Pyrazoles, NRG1-ERBB3, MN, meningioma, Transcriptome, IGF1R/IR, insulin-like growth factor receptor 1/insulin receptor, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81cc1ada7a62b98c37a1556fc7d1099cTest
http://europepmc.org/articles/PMC7949095Test

8

Hepatocyte-specific PKCβ deficiency protects against high-fat diet-induced nonalcoholic hepatic steatosis

المؤلفون: Kamal D. Mehta, Xianlin Han, Vincenzo Coppola, Faizule Hassan, Kedryn K. Baskin, Michael C. Ostrowski, Yaoling Shu, Neil Mehta

المصدر: Molecular Metabolism
Molecular Metabolism, Vol 44, Iss, Pp 101133-(2021)

مصطلحات موضوعية: 0301 basic medicine, Male, Hepatic steatosis, HFD, high-fat diet, Weight Gain, Mice, 0302 clinical medicine, FCCP, trifluoromethoxy carbonyl cyanide phenylhydrazine, Non-alcoholic Fatty Liver Disease, Homeostasis, OCR, oxygen consumption rate, Dietary fats, Chemistry, mTOR, mechanistic target of rapamycin, Fatty liver, TG, triglycerides, Protein kinase cβ, Mitochondria, medicine.anatomical_structure, Mitochondrial respiratory chain, Liver, Hepatocyte, Lipogenesis, IRS, insulin receptor substrate, Original Article, MEK, mitogen-extracellular kinase, Sterol Regulatory Element Binding Protein 1, lcsh:Internal medicine, medicine.medical_specialty, Mitochondria respiratory chain, Dietary lipid, 030209 endocrinology & metabolism, Diet, High-Fat, AKT, protein kinase B, 03 medical and health sciences, Insulin resistance, Internal medicine, Protein Kinase C beta, medicine, WAT, adipose tissue, Animals, Obesity, lcsh:RC31-1245, Molecular Biology, PKCβfl/fl, floxed PKCβ mice, PKCβ, protein kinase Cβ, Lipid metabolism, Cell Biology, medicine.disease, Lipid Metabolism, VLDL, very low-density lipoproteins, Disease Models, Animal, 030104 developmental biology, Endocrinology, Glucose, PKCβHep−/−, hepatocyte-specific PKCβ-deficient mice, Hepatocytes, SREBP-1c, sterol response element-binding protein-1c, Steatosis, Insulin Resistance

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f37ab29dce39395a2e6ad5e16e59348aTest
http://europepmc.org/articles/PMC7785956Test

9

Hepatic deletion of Mboat7 (LPIAT1) causes activation of SREBP-1c and fatty liver

المؤلفون: Shunxing Rong, Xiaorong Fu, Matthew A. Mitsche, Mingfeng Xia, Preethi Chandrasekaran

المصدر: Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100031-(2021)

مصطلحات موضوعية: 0301 basic medicine, phosphatidylinositol, obesity, ACL, ATP citrate lyase, AA, arachidonic acid, ACC, acetyl-CoA carboxylase, 030204 cardiovascular system & hematology, PG, phosphatidylglycerol, Biochemistry, chemistry.chemical_compound, PC, phosphatidylcholine, 0302 clinical medicine, Endocrinology, DAG, diacylglyceride, liver-specific knockout, flux analysis, chemistry.chemical_classification, Liver injury, LPIAT, lysophosphatidylinositol acyltransferase, biology, TMC4, transmembrane channel 4, TG, triglyceride, SREBP cleavage-activating protein, Fatty liver, LPLAT, lysophospholipid acyltransferase, Lipogenesis, IRS, insulin receptor substrate, dKO, double KO, GTT, glucose tolerance test, Arachidonic acid, MBOAT7, membrane-bound O-acyltransferase domain-containing 7, Sterol Regulatory Element Binding Protein 1, Polyunsaturated fatty acid, Research Article, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, PNPLA3, patatin-like phospholipase domain-containing 3, TM6sf2, transmembrane 6 superfamily member 2, QD415-436, DNL, de novo lipogenesis, mTOR, mammalian target of rapamycin, PE, phosphatidylethanolamine, AKT, protein kinase B, PI, phosphatidylinositol, 03 medical and health sciences, Internal medicine, medicine, sterol regulatory element-binding protein 1c, ITT, insulin tolerance test, Triglyceride, Scap, SREBP cleavage-activating protein, membrane-bound O-acyltransferase domain-containing 7, Cell Biology, medicine.disease, ASO, anti-sense oligonucleotide, 030104 developmental biology, chemistry, lysophosphatidylinositol acyltransferase 1, biology.protein, fatty liver disease, lipidomics, Steatosis, MRM, multiple reaction monitoring

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de5a14a108c211284d76c444098061beTest
https://pubmed.ncbi.nlm.nih.gov/32859645Test

10

Macrophage ubiquitin-specific protease 2 modifies insulin sensitivity in obese mice

المؤلفون: Tomomi Miyamoto, Eiki Takahashi, Ichiro Miyoshi, Natsuko Saito, Atsushi Asano, Yoshinori Shimamoto, Kohei Washio, Sanae Fukushima, Shunsuke Kimura, Chitoku Toda, Misato Amagasa, Hiroshi Kitamura, Chieko Nishioka, Shiki Okamoto

المصدر: Biochemistry and Biophysics Reports, Vol 9, Iss C, Pp 322-329 (2017)
Biochemistry and Biophysics Reports

مصطلحات موضوعية: 0301 basic medicine, DMEM, Dulbecco's modified Eagle medium, HFD, high-fat diet, Macrophage, medicine.medical_treatment, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, PI3K, phosphatidylinositol 3-phosphate kinase, Biochemistry, pIRβ, phosphorylated insulin receptor β chain, USP, ubiquitin-specific protease, 0302 clinical medicine, Insulin, lcsh:QD415-436, pAkt, phosphorylated Akt, lcsh:QH301-705.5, SOCS, suppressor of cytokine signaling, Myogenesis, Diabetes, ELISA, enzyme-linked immunosorbent assay, HOMA-IR, homeostatic model assessment as an index of insulin resistance, NEFA, nonesterified fatty acid, medicine.anatomical_structure, IR, insulin receptor, IRS, insulin receptor substrate, Research Article, Genetically modified mouse, medicine.medical_specialty, KD, knock down, Adipose tissue macrophages, Biophysics, 030209 endocrinology & metabolism, Biology, lcsh:Biochemistry, 03 medical and health sciences, Insulin resistance, Tg, transgenic, Internal medicine, medicine, Obesity, KO, knockout, Protease, NCD, normal chow diet, Wild type, Skeletal muscle, T2DM, type 2 diabetes mellitus, medicine.disease, USP, IL, interleukin, 030104 developmental biology, Endocrinology, lcsh:Biology (General), PDK, phosphoinositide-dependent kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db21366930bc0d7858ca686948953bfaTest
http://hdl.handle.net/10659/00005998Test

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