المؤلفون: Emilsson, Gustav, Röder, Evelyn, Malekian, Bita, Xiong, Kunli, Manzi, John, Tsai, Feng-Ching, Cho, Nam-Joon, Bally, Marta, Dahlin, Andreas

المصدر: Frontiers in Chemistry. 7

مصطلحات موضوعية: membranes, curvature, IRSp53, insulin receptor tyrosine kinase substrate p53, plasmons, sensors

وصف الملف: electronic

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-156586Test
https://doi.org/10.3389/fchem.2019.00001Test
https://umu.diva-portal.org/smash/get/diva2:1291071/FULLTEXT01.pdfTest

المؤلفون: Skeberdis, Vytenis A., Lan, Jian-yu, Zheng, Xin, Zukin, R. Suzanne

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2001 Mar . 98(6), 3561-3566.

الوصول الحر: https://www.jstor.org/stable/3055274Test

المؤلفون: Gustav Emilsson, Evelyn Röder, Bita Malekian, Kunli Xiong, John Manzi, Feng-Ching Tsai, Nam-Joon Cho, Marta Bally, Andreas Dahlin

المصدر: Frontiers in Chemistry, Vol 7 (2019)

مصطلحات موضوعية: membranes, curvature, IRSp53, insulin receptor tyrosine kinase substrate p53, plasmons, sensors, Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/article/10.3389/fchem.2019.00001/fullTest; https://doaj.org/toc/2296-2646Test

الوصول الحر: https://doaj.org/article/905d98f739cd423d85f0fce827d7f8e7Test

المؤلفون: Pingping Luo, Rui Zhang, Qian Yu, George L. Tipoe, Ming Zheng, Xiaoming Sun, Yingxia Liu, Jia Xiao, Wei Li, Hong Zhang

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 668-679 (2021)

مصطلحات موضوعية: Alcoholic liver disease, INSR, insulin receptor, TCF/LEF, T-cell factor/lymphoid enhancer factor, AST, aspartate aminotransferase, Pharmacology, TSA, thermal shift assay, 0302 clinical medicine, WAT, white adipose tissues, HSL, hormone sensitive lipase, FFA, free fatty acids, MTT, 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl-tetrazolium bromide, General Pharmacology, Toxicology and Pharmaceutics, NF-κB, nuclear factor kappa B, RER, respiratory exchange ratio, 0303 health sciences, LRP6, low-density lipoprotein receptor related protein 6, TNF, tumor necrosis factor, NAS, NAFLD activity score, biology, TG, triglyceride, Chemistry, NIAAA, National Institute on Alcohol Abuse and Alcoholism, Liver cell, CYP2E1, cytochrome P450 2E1, 030220 oncology & carcinogenesis, LDLR, low-density lipoprotein receptor, NRF2, nuclear factor erythroid 2-related factor 2, IRS, insulin receptor substrate, GTT, glucose tolerance test, Original Article, medicine.symptom, Safety, IRTK, insulin receptor tyrosine kinase, GSK3β, glycogen synthase kinase 3 beta, NAFLD, non-alcoholic fatty liver disease, ALD, alcoholic liver disease, SREBP-1c, sterol regulatory element-binding protein 1c, Inflammation, SPR, surface plasmon resonance, AMPK, adenosine 5′-monophosphate (AMP)-activated protein kinase, SAMC, S-allylmercaptocysteine, 03 medical and health sciences, ADIPOQ, adiponectin, Insulin resistance, ORF, open reading frame, PA, palmitate acid, ALT, alanine aminotransferase, medicine, CPT1, carnitine palmitoyltransferase I, IRS-1, GRB14, growth factor receptor-bound protein 14, Protein kinase B, 030304 developmental biology, ATGL, adipose triglyceride lipase, PPARα, peroxisome proliferator-activated receptor alpha, AKT, lcsh:RM1-950, ALDH2, aldehyde dehydrogenase 2, GSK3β, Lipid metabolism, medicine.disease, S-Allylmercaptocysteine, WT, wild-type, IL, interleukin, TC, total cholesterol, Insulin receptor, FDA, U.S. Food and Drug Administration, lcsh:Therapeutics. Pharmacology, biology.protein, NAC, N-acetyl-cysteine, Steatosis, IGF-1, insulin-like growth factors-1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71348640a2921fa24860e2b42b33f51Test
http://europepmc.org/articles/PMC7982498Test

المؤلفون: Hassan Izzedine, Mark A. Perazella

المصدر: Journal of Onco-Nephrology. 1:49-56

مصطلحات موضوعية: 0301 basic medicine, Insulin receptor tyrosine kinase, Crizotinib, business.industry, Acute kidney injury, Cancer, medicine.disease, Small molecule, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, hemic and lymphatic diseases, 030220 oncology & carcinogenesis, Cancer research, Medicine, Anaplastic lymphoma kinase, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::24481d4a5fd2b282b2e6cf442542e40aTest
https://doi.org/10.5301/jo-n.5000012Test

المؤلفون: Kunli Xiong, Marta Bally, Gustav Emilsson, Feng-Ching Tsai, Andreas B. Dahlin, Bita Malekian, Evelyn Röder, John Manzi, Nam-Joon Cho

المساهمون: AstraZeneca R&D Mölndal, AstraZeneca, Chalmers University of Technology [Göteborg], Laboratoire Physico-Chimie Curie [Institut Curie] (PCC), Institut Curie [Paris]-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Nanyang Technological University [Singapour], Umeå University, School of Materials Science & Engineering

المصدر: Frontiers in Chemistry
Frontiers in Chemistry, Frontiers Media, 2019, 7, pp.1. ⟨10.3389/fchem.2019.00001⟩
Frontiers in Chemistry, Vol 7 (2019)

مصطلحات موضوعية: Materials science, [SDV.BIO]Life Sciences [q-bio]/Biotechnology, 02 engineering and technology, 010402 general chemistry, Curvature, sensors, 01 natural sciences, Physical Chemistry, lcsh:Chemistry, Niobium oxide, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Surface plasmon resonance, Lipid bilayer, insulin receptor tyrosine kinase substrate p53, Plasmon, IRSp53, Original Research, Fysikalisk kemi, Bilayer, General Chemistry, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Engineering::Materials [DRNTU], Chemistry, lcsh:QD1-999, Chemical physics, Membrane curvature, membranes, curvature, 0210 nano-technology, Biosensor, plasmons

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5a310773727a7fa1c717b6e443beffTest
https://hal.sorbonne-universite.fr/hal-02045911Test

المؤلفون: Hidekuni Kaito, Daisuke Nakashima, Toshio Ota, Jie Willey, Shiro Akinaga, Fumito Koizumi, Hiroshi Umehara, Naoto T. Ueno, Makiko Shimizu, Tamer M. Fouad, Norihiko Shiraishi, Yoshimi Maekawa

المصدر: Therapeutic Advances in Medical Oncology, Vol 10 (2018)
Therapeutic Advances in Medical Oncology

مصطلحات موضوعية: 0301 basic medicine, letrozole, medicine.drug_class, Estrogen receptor, Lapatinib, lcsh:RC254-282, Tyrosine-kinase inhibitor, 03 medical and health sciences, breast cancer, 0302 clinical medicine, In vivo, Medicine, lapatinib, Receptor, skin and connective tissue diseases, Original Research, Insulin receptor tyrosine kinase, business.industry, Letrozole, estrogen receptor-positive, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, HER2-positive, In vitro, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, KW-2450, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d752e5218e87030cf7b1a82c4591e71aTest
https://doaj.org/article/e78fa8802280460695e1175fa5a25353Test

المؤلفون: Donghwan Jang, Yunbae Pak, Jaewoong Lee, Kyuho Jeong, Hayeong Kwon

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1853:1022-1034

مصطلحات موضوعية: Insulin receptor substrate-1, Acylation, Caveolin 2, Lipoylation, Glucose uptake, Amino Acid Motifs, Molecular Sequence Data, Intracellular Space, Models, Biological, Receptor tyrosine kinase, Cell Line, Substrate Specificity, Mice, chemistry.chemical_compound, Caveolin-2, Insulin receptor substrate, Cell proliferation and survival, Animals, Humans, Insulin, Amino Acid Sequence, Cysteine, Phosphorylation, Phosphotyrosine, Molecular Biology, Fatty acylation, biology, Fatty Acids, Tyrosine phosphorylation, Cell Biology, Protein-Tyrosine Kinases, IRS2, Rats, Protein Transport, Insulin receptor, Insulin receptor tyrosine kinase, Biochemistry, chemistry, Gene Knockdown Techniques, ROR1, Biocatalysis, Insulin Receptor Substrate Proteins, cardiovascular system, biology.protein, Mitogens, Tyrosine kinase, Protein Binding, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f4547b3bccb43ba3726096ad4ea815Test
https://doi.org/10.1016/j.bbamcr.2015.02.002Test

المؤلفون: Lathamol A. Kurian, Tammy A. Silva, David Sabatino

المصدر: Bioorganic & Medicinal Chemistry Letters. 24:4176-4180

مصطلحات موضوعية: Peptidomimetic, Clinical Biochemistry, Pharmaceutical Science, Ligands, Biochemistry, Structure-Activity Relationship, Drug Discovery, Humans, Protein Kinase Inhibitors, Molecular Biology, chemistry.chemical_classification, Aza Compounds, Insulin receptor tyrosine kinase, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Drug discovery, Organic Chemistry, Nuclear magnetic resonance spectroscopy, Protein-Tyrosine Kinases, In vitro, Random coil, Protein Structure, Tertiary, Molecular Docking Simulation, Enzyme, Molecular Medicine, Phosphorylation, Oligopeptides

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0aba0010afd1707c432341be425d0fdTest
https://doi.org/10.1016/j.bmcl.2014.07.046Test

المؤلفون: Gerald M. Reaven, Salman Azhar, Mileni Josefina Maria Ursich, Bernardo Léo Wajchenberg, R. Nomizo, Rosa Ferreira dos Santos, E. Oliveira

المصدر: Diabetes, Obesity and Metabolism. 2:237-241

مصطلحات موضوعية: Blood Glucose, Male, medicine.medical_specialty, Erythrocytes, Endocrinology, Diabetes and Metabolism, Type 2 diabetes, Endocrinology, Internal medicine, Glyburide, Internal Medicine, medicine, Humans, Hypoglycemic Agents, Distribution (pharmacology), Fasting hyperglycaemia, Insulin receptor tyrosine kinase, biology, business.industry, Middle Aged, medicine.disease, Receptor, Insulin, Metformin, Insulin receptor, Diabetes Mellitus, Type 2, biology.protein, Female, business, Body mass index, Tyrosine kinase, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc49e0c4a42cd6893b22c2205888eac5Test
https://doi.org/10.1046/j.1463-1326.2000.00091.xTest