المؤلفون: Raggi, Chiara, Taddei, Maria Letizia, Sacco, Elena, Navari, Nadia, Correnti, Margherita, Piombanti, Benedetta, Pastore, Mirella, Campani, Claudia, Pranzini, Erica, Iorio, Jessica, Lori, Giulia, Lottini, Tiziano, Peano, Clelia, Cibella, Javier, Lewinska, Monika, Andersen, Jesper B, di Tommaso, Luca, Viganò, Luca, Di Maira, Giovanni, Madiai, Stefania, Ramazzotti, Matteo, Orlandi, Ivan, Arcangeli, Annarosa, Chiarugi, Paola, Marra, Fabio

المصدر: Raggi , C , Taddei , M L , Sacco , E , Navari , N , Correnti , M , Piombanti , B , Pastore , M , Campani , C , Pranzini , E , Iorio , J , Lori , G , Lottini , T , Peano , C , Cibella , J , Lewinska , M , Andersen , J B , di Tommaso , L , Viganò , L , Di Maira , G , Madiai , S , Ramazzotti , M , Orlandi , I , Arcangeli , A , Chiarugi , P ....

مصطلحات موضوعية: Animals, Bile Duct Neoplasms/drug therapy, Carcinogenesis/drug effects, Cell Line, Tumor, Cholangiocarcinoma/drug therapy, Electron Transport Complex II/metabolism, Epithelial-Mesenchymal Transition/drug effects, Gene Silencing, Humans, Indoles/administration & dosage, Male, Metformin/administration & dosage, Mice, Inbred NOD, SCID, Mitochondria/metabolism, Neoplastic Stem Cells/metabolism, Oxidative Phosphorylation/drug effects, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/antagonists & inhibitors, Phenotype, Progression-Free Survival, Propanols/administration & dosage, Signal Transduction/drug effects, Transfection, Treatment Outcome, Tumor Burden/drug effects, Xenograft Model Antitumor Assays

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1016/j.jhep.2020.12.031Test
https://curis.ku.dk/portal/da/publications/mitochondrial-oxidative-metabolism-contributes-to-a-cancer-stem-cell-phenotype-in-cholangiocarcinomaTest(ffe0465b-8987-4d6c-a47c-694d81d5a369).html
https://curis.ku.dk/ws/files/333036705/mitochondrial_oxidative_metabolism_in_cca.pdfTest

المؤلفون: Jarosz-Griffiths, H.H., Scambler, T., Wong, C.H., Lara-Reyna, S., Holbrook, J., Martinon, F., Savic, S., Whitaker, P., Etherington, C., Spoletini, G., Clifton, I., Mehta, A., McDermott, M.F., Peckham, D.

المصدر: eLife, vol. 9, pp. e54556

مصطلحات موضوعية: Adult, Aminophenols/administration & dosage, Aminophenols/therapeutic use, Aminopyridines/administration & dosage, Aminopyridines/therapeutic use, Benzodioxoles/administration & dosage, Benzodioxoles/therapeutic use, Cystic Fibrosis/drug therapy, Cystic Fibrosis/metabolism, Cystic Fibrosis Transmembrane Conductance Regulator/drug effects, Cystic Fibrosis Transmembrane Conductance Regulator/metabolism, Cytokines/metabolism, Down-Regulation, Drug Therapy, Combination, Female, Humans, Indoles/administration & dosage, Indoles/therapeutic use, Inflammation/diet therapy, Inflammation/metabolism, Interleukin-18/blood, Interleukin-1beta/blood, Male, Monocytes/drug effects, Monocytes/metabolism, Quinolones/administration & dosage, Quinolones/therapeutic use, Tumor Necrosis Factor-alpha/blood, Young Adult

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32118580; info:eu-repo/semantics/altIdentifier/eissn/2050-084X; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_E0016C3B61204; https://serval.unil.ch/notice/serval:BIB_E0016C3B6120Test; urn:issn:2050-084X; https://serval.unil.ch/resource/serval:BIB_E0016C3B6120.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_E0016C3B61204Test

الإتاحة: https://doi.org/10.7554/eLife.54556Test
https://serval.unil.ch/notice/serval:BIB_E0016C3B6120Test
https://serval.unil.ch/resource/serval:BIB_E0016C3B6120.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_E0016C3B61204Test

المؤلفون: Ray-Coquard, Isabelle, Cibula, David, Mirza, Mansoor R, Reuss, Alexander, Ricci, Caterina, Colombo, Nicoletta, Koch, Horst, Goffin, Frédéric, González-Martin, Antonio, Ottevanger, Petronella B, Baumann, Klaus, Bjørge, Line, Lesoin, Anne, Burges, Alexander, Rosenberg, Per, Gropp-Meier, Martina, Harrela, Maija, Harter, Philipp, Frenel, Jean-Sébastien, Minarik, Tomas, Pisano, Carmela, Hasenburg, Annette, Merger, Michael, du Bois, Andreas, AGO Study Group-led GCIG/ENGOT Intergroup Consortium

المصدر: International Journal of Cancer, 146 (2), 439 - 448 (2020-01-15)

مصطلحات موضوعية: antiangiogenic, nintedanib, ovarian cancer, overall survival, tyrosine kinase inhibitor, Indoles, Placebos, Protein Kinase Inhibitors, Carboplatin, Paclitaxel, Adult, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols/administration & dosage, Antineoplastic Combined Chemotherapy Protocols/adverse effects, Carboplatin/administration & dosage, Carboplatin/adverse effects, Chemotherapy, Adjuvant/adverse effects, Adjuvant/methods, Cytoreduction Surgical Procedures, Female, Follow-Up Studies, Humans, Indoles/administration & dosage, Indoles/adverse effects, Middle Aged, Neoplasm Staging, Ovarian Neoplasms/mortality, Ovarian Neoplasms/pathology

العلاقة: urn:issn:0020-7136; urn:issn:1097-0215; https://orbi.uliege.be/handle/2268/309155Test; info:hdl:2268/309155; https://orbi.uliege.be/bitstream/2268/309155/1/2020-IJC-Ov-Nintedanib-Ray%20Coquard.pdfTest; scopus-id:2-s2.0-85072066391; info:pmid:31381147

الإتاحة: https://doi.org/10.1002/ijc.32606Test
https://orbi.uliege.be/handle/2268/309155Test
https://orbi.uliege.be/bitstream/2268/309155/1/2020-IJC-Ov-Nintedanib-Ray%20Coquard.pdfTest

المؤلفون: de Weger, Vincent A, de Jonge, Maja, Langenberg, Marlies H G, Schellens, Jan H M, Lolkema, Martijn, Varga, Andrea, Demers, Brigitte, Thomas, Koruth, Hsu, Karl, Tuffal, Gilles, Goodstal, Samantha, Macé, Sandrine, Deutsch, Eric

المساهمون: Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology

مصطلحات موضوعية: Adult, Aged, Antineoplastic Combined Chemotherapy Protocols/administration & dosage, Dose-Response Relationship, Drug, Female, Gene Expression Regulation, Neoplastic/drug effects, Humans, Indoles/administration & dosage, MAP Kinase Kinase Kinases/antagonists & inhibitors, Male, Maximum Tolerated Dose, Middle Aged, Neoplasms/classification, Niacinamide/administration & dosage, Protein Kinase Inhibitors/administration & dosage, Proto-Oncogene Proteins B-raf/genetics, Proto-Oncogene Proteins c-mdm2/antagonists & inhibitors, Proto-Oncogene Proteins p21(ras)/genetics, Spiro Compounds/administration & dosage, Thrombocytopenia/chemically induced, Tumor Suppressor Protein p53/genetics

وصف الملف: image/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/391177Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/391177Test

المصدر: CheckMate 214 Investigators 2018 , ' Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma ' , The New England Journal of Medicine , vol. 378 , no. 14 , pp. 1277-1290 . https://doi.org/10.1056/NEJMoa1712126Test

مصطلحات موضوعية: Adult, Aged, 80 and over, Antibodies, Monoclonal/administration & dosage, Antineoplastic Agents, Immunological/administration & dosage, Antineoplastic Combined Chemotherapy Protocols/adverse effects, Carcinoma, Renal Cell/drug therapy, Disease-Free Survival, Humans, Indoles/administration & dosage, Ipilimumab/administration & dosage, Kidney Neoplasms/drug therapy, Male, Middle Aged, Pyrroles/administration & dosage, Quality of Life, Risk, Survival Analysis, Survival Rate

الإتاحة: https://doi.org/10.1056/NEJMoa1712126Test
https://pure.au.dk/portal/da/publications/nivolumab-plus-ipilimumab-versus-sunitinib-in-advanced-renalcell-carcinomaTest(9d613da7-a490-4e1e-940a-79cc1309b512).html
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972549/pdf/nihms966108.pdfTest

المؤلفون: Theunissen, Eef L, Hutten, Nadia R P W, Mason, Natasha L, Toennes, Stefan W., Kuypers, Kim P C, de Sousa Fernandes Perna, Eliza B, Ramaekers, Johannes G

المصدر: Theunissen , E L , Hutten , N R P W , Mason , N L , Toennes , S W , Kuypers , K P C , de Sousa Fernandes Perna , E B & Ramaekers , J G 2018 , ' Neurocognition and subjective experience following acute doses of the synthetic cannabinoid JWH-018 : a phase 1, placebo-controlled, pilot study ' , British Journal of Pharmacology , vol. 175 , no. 1 , pp. 18-28 . https://doi.org/10.1111/bph.14066Test

مصطلحات موضوعية: Journal Article, MOTOR CONTROL, MARIJUANA, ALCOHOL, PERFORMANCE, INHALATION, SPICE, MICE, SERUM, TANDEM MASS-SPECTROMETRY, RECEPTOR AGONIST, Single-Blind Method, Humans, Male, Mental Status and Dementia Tests, Naphthalenes/administration & dosage, Indoles/administration & dosage, Young Adult, Street Drugs/pharmacology, Adult, Female, Affect/drug effects, Cross-Over Studies, Pilot Projects, Cognition/drug effects, Adolescent, Receptor, Cannabinoid, CB1

الإتاحة: https://doi.org/10.1111/bph.14066Test
https://cris.maastrichtuniversity.nl/en/publications/db4a0475-d3e4-4829-9008-0c5c9c824f22Test

المؤلفون: Matteo Ramazzotti, Luca Viganò, Mirella Pastore, Maria Letizia Taddei, Monika Lewinska, Javier Cibella, Clelia Peano, Erica Pranzini, Luca Di Tommaso, Elena Sacco, Jessica Iorio, Paola Chiarugi, S. Madiai, Jesper B. Andersen, Chiara Raggi, Ivan Orlandi, B. Piombanti, Giovanni Di Maira, Margherita Correnti, N. Navari, Tiziano Lottini, Annarosa Arcangeli, Giulia Lori, Claudia Campani, Fabio Marra

المساهمون: Raggi, C, Taddei, M, Sacco, E, Navari, N, Correnti, M, Piombanti, B, Pastore, M, Campani, C, Pranzini, E, Iorio, J, Lori, G, Lottini, T, Peano, C, Cibella, J, Lewinska, M, Andersen, J, di Tommaso, L, Vigano, L, Di Maira, G, Madiai, S, Ramazzotti, M, Orlandi, I, Arcangeli, A, Chiarugi, P, Marra, F

المصدر: Raggi, C, Taddei, M L, Sacco, E, Navari, N, Correnti, M, Piombanti, B, Pastore, M, Campani, C, Pranzini, E, Iorio, J, Lori, G, Lottini, T, Peano, C, Cibella, J, Lewinska, M, Andersen, J B, di Tommaso, L, Viganò, L, Di Maira, G, Madiai, S, Ramazzotti, M, Orlandi, I, Arcangeli, A, Chiarugi, P & Marra, F 2021, ' Mitochondrial oxidative metabolism contributes to a cancer stem cell phenotype in cholangiocarcinoma ', Journal of Hepatology, vol. 74, no. 6, pp. 1373-1385 . https://doi.org/10.1016/j.jhep.2020.12.031Test

مصطلحات موضوعية: Male, 0301 basic medicine, Indoles, Carcinogenesis, Propanols, PGC-1α, Mice, SCID, Mitochondrion, Oxidative Phosphorylation, Cholangiocarcinoma, Mice, Metformin/administration & dosage, 0302 clinical medicine, Mice, Inbred NOD, Signal Transduction/drug effects, SR-18292, CCLP1, Propanols/administration & dosage, Oxidative Phosphorylation/drug effects, Electron Transport Complex II, Indoles/administration & dosage, OXPHOS, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/antagonists & inhibitors, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Phenotype, Metformin, Progression-Free Survival, Mitochondria, Tumor Burden, Treatment Outcome, Neoplastic Stem Cells, 030211 gastroenterology & hepatology, Epithelial-Mesenchymal Transition/drug effects, Signal transduction, Electron Transport Complex II/metabolism, Tumor Burden/drug effects, Signal Transduction, Epithelial-Mesenchymal Transition, Oxidative phosphorylation, Biology, Transfection, 03 medical and health sciences, HUCCT1, Neoplastic Stem Cells/metabolism, Cancer stem cell, Cell Line, Tumor, Mitochondria/metabolism, Cholangiocarcinoma/drug therapy, Animals, Humans, Gene silencing, Gene Silencing, Hepatology, Bile Duct Neoplasms/drug therapy, Carcinogenesis/drug effects, Xenograft Model Antitumor Assays, Embryonic stem cell, 030104 developmental biology, Bile Duct Neoplasms, Mitochondrial biogenesis, Cancer research

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef501d3fbda1682299d6ec0832b7ea5Test
https://doi.org/10.1016/j.jhep.2020.12.031Test

المساهمون: College of Medicine, Dept. of Internal Medicine, Jia�륣orng Kao, Ming�륧ung Yu, Cheng�륻uan Peng, Jeong Heo, Chi�륥en Chu, Ting�륳sung Chang, Youn�륥ae Lee, Tsung�륣ui Hu, Ki Tae Yoon, Seung Woon Paik, Young Suk Lim, Sang Hoon Ahn, Vasily Isakov, Fiona McPhee, Wenhua Hu, Eugene Scott Swenson, Philip D Yin, Michelle Treitel, Ahn, Sang Hoon

مصطلحات موضوعية: Adult, Aged, 80 and over, Benzazepines/administration & dosage, Cohort Studies, Drug Combinations, Female, Follow-Up Studies, Genotype, Hepacivirus/genetics, Hepatitis C, Chronic/drug therapy, Chronic/virology, Humans, Imidazoles/administration & dosage, Indoles/administration & dosage, Isoquinolines/administration & dosage, Male, Middle Aged, Republic of Korea, Russia, Sulfonamides/administration & dosage, Taiwan, Treatment Outcome, Young Adult, Asia, NS5A, hepatitis, treatment

العلاقة: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY; J01417; OAK-2017-07726; https://ir.ymlib.yonsei.ac.kr/handle/22282913/161709Test; T201705622; JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, Vol.32(12) : 1998-2005, 2017

الإتاحة: https://doi.org/10.1111/jgh.13796Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/161709Test

المساهمون: College of Medicine, Dept. of Internal Medicine, J. J. Knox, C. H. Barrios, T. M. Kim, T. Cosgriff, V. Srimuninnimit, K. Pittman, R. Sabbatini, S. Y. Rha, T. W. Flaig, R. D. Page, J. T. Beck, F. Cheung, S. Yadav, P. Patel, L. Geoffrois, J. Niolat, N. Berkowitz, M. Marker, D. Chen, R. J. Motzer, Rha, Sun Young

مصطلحات موضوعية: Adult, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Carcinoma, Renal Cell/drug therapy, Cross-Over Studies, Everolimus/administration & dosage, Female, Humans, Indoles/administration & dosage, Kidney Neoplasms/drug therapy, Male, Middle Aged, Prognosis, Pyrroles/administration & dosage, Survival Analysis, Young Adult, everolimus, renal cell carcinoma, sequential targeted therapy, sunitinib

العلاقة: ANNALS OF ONCOLOGY; J00171; OAK-2017-05335; https://ir.ymlib.yonsei.ac.kr/handle/22282913/160952Test; T201703713; ANNALS OF ONCOLOGY, Vol.28(6) : 1339-1345, 2017

الإتاحة: https://doi.org/10.1093/annonc/mdx075Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/160952Test

المؤلفون: van der Hiel, Bernies, Haanen, John B A G, Stokkel, Marcel P M, Peeper, Daniel S., Jimenez, Connie R., Beijnen, Jos H, van de Wiel, Bart A., Boellaard, Ronald, van den Eertwegh, Alfons J M, van Tinteren, H., Wessels, Lodewyk F A, Lolkema, Martijn P J K, Hoekstra, Otto S, Hospers, Geke A P, Brouwers, Adrienne H, Koornstra, R.H.T., Arens, A. I. J., de Vos, F. Y.F.L., Hobbelink, M. G.G., Kapiteijn, H. W., de Geus-Oei, L. F., Kruit, W. H.J., Verzijlbergen, F.J., Aarts, M. J.B., Mottaghy, F. M., de Groot, J. W.B., Knollema, S., Piersma, D., Agool, A., Vreugdenhil, Art, Liem, I H, van den Berkmortel, Franchette W P J, Schreurs, M.W., REPOSIT study group

المساهمون: MS Medische Oncologie, Cancer, UMC Utrecht, Arts-assistenten Nucleaire Geneesk.

مصطلحات موضوعية: F-FDG, F-FLT, BRAF inhibitor, MEK inhibitor, PET/CT, Resistance, Stage IIIc/IV melanoma, Sulfonamides/administration & dosage, Melanoma/diagnostic imaging, Azetidines/administration & dosage, Piperidines/administration & dosage, Skin Neoplasms/diagnostic imaging, Humans, Drug Resistance, Neoplasm, Treatment Outcome, Positron-Emission Tomography, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Indoles/administration & dosage, Disease-Free Survival, Vemurafenib, Multicenter Studies as Topic, Neoplasm Staging, Research Design, Clinical Trials, Phase II as Topic, Genetics, Oncology, Cancer Research, Journal Article

وصف الملف: image/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/356417Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/356417Test