المؤلفون: Marina Alexeeva, Marivi Nabong Moen, Xiang Ming Xu, Anette Rasmussen, Ingar Leiros, Finn Kirpekar, Arne Klungland, Lene Alsøe, Hilde Nilsen, Svein Bjelland

المصدر: Frontiers in Immunology, Vol 12 (2021)

مصطلحات موضوعية: human UNG, class switch recombination, somatic hypermutation, immunoglobulin diversification, cytosine deamination, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fimmu.2021.762032/fullTest; https://doaj.org/toc/1664-3224Test

الوصول الحر: https://doaj.org/article/d7f045b476d94cb59da2ab03aa3d7809Test

المؤلفون: Marina Alexeeva (4917646), Marivi Nabong Moen (11865740), Xiang Ming Xu (11865743), Anette Rasmussen (11865746), Ingar Leiros (5278595), Finn Kirpekar (505584), Arne Klungland (235737), Lene Alsøe (4021790), Hilde Nilsen (121041), Svein Bjelland (4917643)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, human UNG, class switch recombination, somatic hypermutation, immunoglobulin diversification, cytosine deamination

العلاقة: https://figshare.com/articles/presentation/Presentation_1_Intrinsic_Strand-Incision_Activity_of_Human_UNG_Implications_for_Nick_Generation_in_Immunoglobulin_Gene_Diversification_pdf/17359094Test

الإتاحة: https://doi.org/10.3389/fimmu.2021.762032.s001Test

المؤلفون: Alexeeva, Marina, Moen, Marivi Nabong, Xu, Xiang Ming, Rasmussen, Anette, Leiros, Ingar, Kirpekar, Finn, Klungland, Arne, Alsøe, Lene, Nilsen, Hilde, Bjelland, Svein

المصدر: Alexeeva , M , Moen , M N , Xu , X M , Rasmussen , A , Leiros , I , Kirpekar , F , Klungland , A , Alsøe , L , Nilsen , H & Bjelland , S 2021 , ' Intrinsic Strand-Incision Activity of Human UNG : Implications for Nick Generation in Immunoglobulin Gene Diversification ' , Frontiers in Immunology , vol. 12 , 762032 . https://doi.org/10.3389/fimmu.2021.762032Test

مصطلحات موضوعية: class switch recombination, cytosine deamination, human UNG, immunoglobulin diversification, somatic hypermutation

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/99e780ef-8461-45e1-8a4e-aee896dee62cTest

الإتاحة: https://doi.org/10.3389/fimmu.2021.762032Test
https://portal.findresearcher.sdu.dk/da/publications/99e780ef-8461-45e1-8a4e-aee896dee62cTest
https://findresearcher.sdu.dk/ws/files/197562658/fimmu_12_762032.pdfTest

المؤلفون: Jue Hou, Weijian Ye, Hooi Linn Loo, Lan Hiong Wong, Jianzhu Chen

المصدر: Frontiers in Immunology, Vol 11 (2020)

مصطلحات موضوعية: dengue virus, vaccine development, sequential immunization, immunoglobulin diversification, epitope-decreasing, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/article/10.3389/fimmu.2020.585133/fullTest; https://doaj.org/toc/1664-3224Test

الوصول الحر: https://doaj.org/article/3765ca9a2d464d40bd69c07bcb126e0aTest

المؤلفون: Caldwell, R.B., Braselmann, H., Heuer, S., Schötz, U., Zitzelsberger, H.

المصدر: Immunol. Cell Biol. 96, 948-957 (2018)

مصطلحات موضوعية: Activation-induced Cytosine Deaminase (aid Aicd), Cis-targeting Elements, Dna Regulatory Motifs, Immunoglobulin Diversification, Somatic Hypermutation, Transgene Diversification

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/29665088; info:eu-repo/semantics/altIdentifier/wos/WOS:000448862900008; info:eu-repo/semantics/altIdentifier/isbn/0818-9641; info:eu-repo/semantics/altIden; https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=53413Test; urn:isbn:0818-9641; urn:issn:0818-9641; urn:issn:1440-1711

الإتاحة: https://doi.org/10.1111/imcb.12158Test
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=53413Test

المؤلفون: Jianzhu Chen, Jue Hou, Weijian Ye, Lan Hiong Wong, Hooi Linn Loo

المصدر: Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)

مصطلحات موضوعية: 0301 basic medicine, Immunoglobulin gene, lcsh:Immunologic diseases. Allergy, animal diseases, Immunology, chemical and pharmacologic phenomena, Dengue Vaccines, Dengue virus, medicine.disease_cause, Epitope, Dengue, 03 medical and health sciences, epitope-decreasing, Epitopes, Mice, 0302 clinical medicine, Immune system, Antigen, medicine, Immunology and Allergy, Animals, Neutralizing antibody, Antigens, Viral, Original Research, biology, dengue virus, Vaccination, biochemical phenomena, metabolism, and nutrition, Virology, Mice, Inbred C57BL, 030104 developmental biology, Immunization, vaccine development, sequential immunization, biology.protein, bacteria, immunoglobulin diversification, Antibody, lcsh:RC581-607, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec88c06cdb0b005f79787733013f1f5Test
http://europepmc.org/articles/PMC7545740Test

المؤلفون: Stephen J. Elledge, Daniela Rhodes, Allysia J. Matthews, Simin Zheng, Yan Kee Ng, Kayleigh Herrick-Reynolds, Alec J. Wishnie, Emily Sible, Jee Eun Choi, Bao Q. Vuong, Numa Rahman

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Male, 0301 basic medicine, UNG, uracil DNA glycosylase, Regulator, Sequence Homology, HDAC, histone deacetylase, KIAA1841, Biochemistry, CSR, class switch recombination, Mice, SMRT, silencing mediator of retinoic acid and thyroid hormone receptor, RNA, Small Interfering, BER, base excision repair, Recombination, Genetic, B-Lymphocytes, corepressor, SANBR, SANT and BTB domain regulator of CSR, DNA repair protein XRCC4, Cell biology, ChIP, chromatin immunoprecipitation, DNA-Binding Proteins, BTB-POZ Domain, EXO1, Exonuclease I, AID, activation-induced cytidine deaminase, N-CoR, nuclear corepressor, Female, Research Article, SANT domain, SEC, size-exclusion chromatography, Lymphoma, B-Cell, DNA recombination, chemical and pharmacologic phenomena, MMR, mismatch repair, Biology, XRCC4, X-ray repair cross complementing 4, 03 medical and health sciences, GST, glutathione-S-transferase, Animals, Humans, DSB, double-strand break, Amino Acid Sequence, Molecular Biology, B cells, 030102 biochemistry & molecular biology, Cell Biology, Ig, immunoglobulin, Immunoglobulin Class Switching, Mice, Inbred C57BL, APE, apurinic/apyrimidinic endonuclease, 030104 developmental biology, Immunoglobulin class switching, immunoglobulin diversification, Histone deacetylase, Corepressor, Chromatin immunoprecipitation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20af4210aa5b816173bf48b6a948ee34Test
https://doi.org/10.1016/j.jbc.2021.100625Test

المؤلفون: Julian E. Sale, Marina Romanello, Davide Schiavone, Alexander Frey

المصدر: The EMBO Journal

مصطلحات موضوعية: 0301 basic medicine, RNase P, Immunology, Immunoglobulin Variable Region, DNA, Single-Stranded, Biology, histone H3.3, Chromatin, Epigenetics, Genomics & Functional Genomics, Article, General Biochemistry, Genetics and Molecular Biology, Cell Line, Histones, 03 medical and health sciences, chemistry.chemical_compound, Histone H3, Transcription (biology), Cytidine Deaminase, activation‐induced deaminase (AID), Animals, Nucleosome, Molecular Biology, Gene, General Immunology and Microbiology, General Neuroscience, DNA Replication, Repair & Recombination, Articles, Cytidine deaminase, Molecular biology, single‐stranded DNA, 030104 developmental biology, Histone, chemistry, biology.protein, immunoglobulin diversification, transcription, Chickens, DNA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de9920e9f2f9b03023ce708352220f5dTest
https://doi.org/10.15252/embj.201693958Test

المؤلفون: Steffen Heuer, Herbert Braselmann, Randolph B. Caldwell, U. Schötz, Horst Zitzelsberger

المصدر: Immunol. Cell Biol. 96, 948-957 (2018)

مصطلحات موضوعية: 0301 basic medicine, Transgene, Immunology, Gene Conversion, Somatic hypermutation, Heterologous, Locus (genetics), Computational biology, Biology, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Cytidine Deaminase, Animals, Immunology and Allergy, Activation-induced Cytosine Deaminase (aid Aicd), Cis-targeting Elements, Dna Regulatory Motifs, Immunoglobulin Diversification, Somatic Hypermutation, Transgene Diversification, Gene conversion, B-Lymphocytes, Cell Biology, Cytidine deaminase, Immunoglobulin Class Switching, 030104 developmental biology, chemistry, Gain of Function Mutation, Somatic Hypermutation, Immunoglobulin, Chickens, Recombination, DNA

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2172a5f92b9fc52507979741dcc17511Test
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=53413Test

المؤلفون: Nguyen, Thuy Vy

مرشدي الرسالة: Paris 11, Rosselli, Filippo

مصطلحات موضوعية: Voie Anémie de Fanconi, Diversifications des immunoglobulines, Recombinaison V(D)J, Hypermutation somatiques (SHM), Changement de classe par recombinaison (CSR), Fanconi anemia pathway, Immunoglobulin diversification, V(D)J recombination, Somatic hypermutation (SHM), Class switch recombination (CSR)

الإتاحة: http://www.theses.fr/2013PA112268Test