المؤلفون: Igoillo-Esteve, Mariana, Maugeri, Dante, Stern, Ana L., Beluardi, Paula, Cazzulo, Juan J.

المصدر: Anais da Academia Brasileira de Ciências. December 2007 79(4)

مصطلحات موضوعية: Trypanosoma cruzi, Chagas disease, pentose phosphate pathway, oxidative stress, NADPH generation

وصف الملف: text/html

الوصول الحر: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652007000400007Test

المؤلفون: Gorgogietas, Vyron, Rajaei, Bahareh, Chae, Hee-Young, Santacreu, Bruno J, Marín-Cañas, Sandra, Salpea, Paraskevi, Sawatani, Toshiaki, Musuaya, Anyishai, Arroyo, María N, Moreno-Castro, Cristina, Benabdallah, Khadija, Demarez, Celine, Toivonen, Sanna, Cosentino, Cristina, Pachera, Nathalie, Lytrivi, Maria, Cai, Ying, Carnel, Lode, Brown, Cris, Urano, Fumihiko, Marchetti, Piero, Gilon, Patrick, Eizirik, Decio L, Cnop, Miriam, Igoillo-Esteve, Mariana

المساهمون: UCL - SSS/IREC/EDIN - Pôle d'endocrinologie, diabète et nutrition

المصدر: Diabetologia, Vol. 66, no.7, p. 1306-1321 (2023)

مصطلحات موضوعية: Humans, Animals, Mice, Wolfram Syndrome, Exenatide, Induced Pluripotent Stem Cells, Optic Atrophy, Insulin-Secreting Cells, Knockout, GLP-1R agonists, Human pancreatic beta cells, iPSC-derived beta cells, iPSC-derived neurons

العلاقة: boreal:275993; http://hdl.handle.net/2078.1/275993Test; info:pmid/36995380; urn:ISSN:0012-186X; urn:EISSN:1432-0428

الإتاحة: https://doi.org/10.1007/s00125-023-05905-8Test
http://hdl.handle.net/2078.1/275993Test

المؤلفون: González Moro, Itziar, García Etxebarria, Koldo, Mendoza Gómez, Luis Manuel, Fernández Jiménez, Nora, Mentxaka Salgado, Jon, Olazagoitia Garmendia, Ane, Nicol Arroyo, María, Sawatani, Toshiaki, Moreno Castro, Cristina, Vinci, Chiara, Op de Beek, Anne, Cnop, Miriam, Igoillo Esteve, Mariana, Santín Gómez, Izortze

المساهمون: European Commission

وصف الملف: application/pdf

العلاقة: info:eu-repo/grantAgreement/EC/H2020/801505; info:eu-repo/grantAgreement/MICINN/PID2019-104475GA-I00; Advanced Science 10(25) : (2023) // Article ID 2300063; http://hdl.handle.net/10810/62584Test

الإتاحة: https://doi.org/10.1002/advs.202300063Test
http://hdl.handle.net/10810/62584Test

المؤلفون: Gonzalez-Moro, Itziar, Garcia-Etxebarria, Koldo G-E, K, Mendoza, Luis Manuel M LM, Fernández-Jiménez, Nora FJN, Mentxaka, Jon MJ, Olazagoitia-Garmendia, Ane, Arroyo, Maria Nicol, Sawatani, Toshiaki, Moreno Castro, Cristina, Vinci, Chiara, Op De Beeck, Anne, Cnop, Miriam, Igoillo Esteve, Mariana, Santin, Izortze

المصدر: Advanced Science

مصطلحات موضوعية: Sciences bio-médicales et agricoles, Sciences biomédicales

وصف الملف: 1 full-text file(s): application/pdf

العلاقة: uri/info:doi/10.1002/advs.202300063; uri/info:doi/10.1101/2022.12.01.518685; uri/info:pmid/37382191; uri/info:scp/85163786412; https://dipot.ulb.ac.be/dspace/bitstream/2013/359748/3/2022.12.01.518685.full.pdfTest; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/359748Test

الإتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/359748Test
https://dipot.ulb.ac.be/dspace/bitstream/2013/359748/3/2022.12.01.518685.full.pdfTest

المؤلفون: Fantuzzi, Federica, Toivonen, Sanna, Schiavo, Andrea Alex, Chae, Hee-Young, Tariq, Mohammad, Sawatani, Toshiaki, Pachera, Nathalie, Cai, Ying, Vinci, Chiara, Virgilio, Enrico, Ladriere, Laurence, Suleiman, Mara, Marchetti, Piero, Jonas, Jean-Christophe, Gilon, Patrick, Eizirik, Décio L., Igoillo-Esteve, Mariana, Cnop, Miriam

المساهمون: UCL - SSS/IREC/EDIN - Pôle d'endocrinologie, diabète et nutrition

المصدر: Frontiers in cell and developmental biology, Vol. 10, no. 1, p. 967765 [1-13] (2022)

مصطلحات موضوعية: Cell Biology, Developmental Biology

العلاقة: boreal:264456; http://hdl.handle.net/2078.1/264456Test; info:pmid/; urn:EISSN:2296-634X

الإتاحة: https://doi.org/10.3389/fcell.2022.967765Test
http://hdl.handle.net/2078.1/264456Test

المؤلفون: Sanchez Caballero, Laura, Rajaei, Bahareh, Demarez, Céline, Heeyoung, Chae, Gorgogietas, Vyron, Musuaya, Anyishaï, Arroyo, Maria Nicol, Salpea, Paraskevi, Toivonen, Sanna, Cosentino, Cristina, Pachera, Nathalie, Cai, Ying, Sawatani, Toshiaki, Carnel, Lode, Brown, Chris CB, Urano, Fumihiko, Gilon, Patrick, Eizirik, Decio L., Cnop, Miriam, Igoillo Esteve, Mariana

المساهمون: Annual Congres of the Societé Francophone du diabète (2021-09-09: (online presentation))

مصطلحات موضوعية: Sciences bio-médicales et agricoles

وصف الملف: 1 full-text file(s): application/pdf

العلاقة: https://dipot.ulb.ac.be/dspace/bitstream/2013/326387/3/AbstractSFD2020.pdfTest; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/326387Test

الإتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/326387Test
https://dipot.ulb.ac.be/dspace/bitstream/2013/326387/3/AbstractSFD2020.pdfTest

المؤلفون: De Franco, Elisa, Lytrivi, Maria, Ibrahim, Hazem, Montaser, Hossam, Wakeling, Matthew N., Fantuzzi, Federica, Patel, Kashyap, Demarez, Celine, Cai, Ying, Igoillo-Esteve, Mariana, Cosentino, Cristina, Lithovius, Väinö, Vihinen, Helena, Jokitalo, Eija, Laver, Thomas W., Johnson, Matthew B., Sawatani, Toshiaki, Shakeri, Hadis, Pachera, Nathalie, Haliloglu, Belma, Ozbek, Mehmet Nuri, Unal, Edip, Yildirim, Ruken, Godbole, Tushar, Yildiz, Melek, Aydin, Banu, Bilheu, Angeline, Suzuki, Ikuo, Flanagan, Sarah E., Vanderhaeghen, Pierre, Senee, Valerie, Julier, Cecile, Marchetti, Piero, Eizirik, Decio L., Ellard, Sian, Saarimäki-Vire, Jonna, Otonkoski, Timo, Cnop, Miriam, Hattersley, Andrew T.

المساهمون: Centre of Excellence in Stem Cell Metabolism, STEMM - Stem Cells and Metabolism Research Program, Research Programs Unit, Institute of Biotechnology, Electron Microscopy, University Management, Helsinki One Health (HOH), HUS Children and Adolescents, Timo Pyry Juhani Otonkoski / Principal Investigator, Children's Hospital

مصطلحات موضوعية: PROTEIN RESPONSE CONTRIBUTES, PANCREATIC BETA-CELLS, CORTICAL NEUROGENESIS, TRANSCRIPTION FACTOR, GOLGI STRESS, ER STRESS, GENERATION, EXPRESSION, APOPTOSIS, PUMA, 3123 Gynaecology and paediatrics

وصف الملف: application/pdf

العلاقة: We thank the families for participating in the study. We are also grateful to Rebecca Ward and Richard Caswell (University of Exeter Medical School), Isabelle Millard and Anyishai Musuaya (ULB Center for Diabetes Research), and Anne Degrave (Faculte de Medecine Paris-Diderot, Universite de Paris). Special thanks of gratitude to Jarkko Ustinov and Solja Eurola (Biomedicum Stem Cell Center, University of Helsinki) for excellent technical and experimental support. We thank Diego Balboa Alonso (Centre for Genomic Regulation, Barcelona) for professional guidance and support. EDF is a Diabetes UK RD Lawrence Fellow (19/005971). ATH and SE are the recipients of a Wellcome Trust Senior Investigator award (grant WT098395/Z/12/Z), and ATH is employed as a core member of staff within the National Institute for Health Research-funded Exeter Clinical Research Facility and is an NIHR senior investigator. SEF has a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (grant 105636/Z/14/Z). This work was supported by grants from the Fonds Erasme to ML and MC; grants from the Fondation ULB, the Fonds National de la Recherche Scientifique (FNRS), the Brussels Capital Region Innoviris project DiaType, and the Francophone Foundation for Diabetes Research (sponsored by the French Diabetes Federation, Abbott, Eli Lilly, Merck Sharp & Dohme, and Novo Nordisk) to MC; and the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement 115797 (INNODIA) and 945268 (INNODIA HARVEST). This Joint Undertaking receives support from the Union's Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations, JDRF, and the Leona M. and Harry B. Helmsley Charitable Trust (to PM, DLE, TO, and MC). DLE is funded by WELBIO/FRFS (WELBIO-CR-2019C-04), Belgium. Work in the TO laboratory was funded by the Academy of Finland (grant 297466 and MetaStem Center of Excellence grant 312437), the Sigrid Juselius Foundation, the Novo Nordisk Foundation, and Helsinki University Hospital research funds. Work in the PV laboratory was funded by the Belgian FRS/FNRS, the European Research Council (ERC Adv Grant GENDEVOCORTEX), the WELBIO Program of the Walloon Region, the AXA Research Fund, the Fondation ULB, the ERA-NET MicroKin, and the Vlaams Instituut voor Biotechnologie (VIB).; De Franco , E , Lytrivi , M , Ibrahim , H , Montaser , H , Wakeling , M N , Fantuzzi , F , Patel , K , Demarez , C , Cai , Y , Igoillo-Esteve , M , Cosentino , C , Lithovius , V , Vihinen , H , Jokitalo , E , Laver , T W , Johnson , M B , Sawatani , T , Shakeri , H , Pachera , N , Haliloglu , B , Ozbek , M N , Unal , E , Yildirim , R , Godbole , T , Yildiz , M , Aydin , B , Bilheu , A , Suzuki , I , Flanagan , S E , Vanderhaeghen , P , Senee , V , Julier , C , Marchetti , P , Eizirik , D L , Ellard , S , Saarimäki-Vire , J , Otonkoski , T , Cnop , M & Hattersley , A T 2020 , ' YIPF5 mutations cause neonatal diabetes and microcephaly through endoplasmic reticulum stress ' , Journal of Clinical Investigation , vol. 130 , no. 12 , pp. 6338-6353 . https://doi.org/10.1172/JCI141455Test; ORCID: /0000-0003-3862-9237/work/86937061; ORCID: /0000-0002-1537-5548/work/86940213; ORCID: /0000-0002-4159-6934/work/86940724; ORCID: /0000-0003-0879-1807/work/91817487; 379a2ea2-80c6-466a-9ee0-c4b72806033d; http://hdl.handle.net/10138/324513Test; 000600340600004

الإتاحة: http://hdl.handle.net/10138/324513Test

المؤلفون: Lytrivi, Maria, Senée, Valérie, Salpea, Paraskevi, Fantuzzi, Federica, Philippi, Anne, Abdulkarim, Baroj, Sawatani, Toshiaki, Marin Canas, Sandra, Pachera, Nathalie, Degavre, Anne, Singh, Pratibha, Derbois, Céline, Lechner, Doris, Ladrière, Laurence, Igoillo Esteve, Mariana, Cosentino, Cristina, Marselli, Lorella, Deleuze, Jean François, Marchetti, Piero, Eizirik, Decio L., Nicolino, Marc, Chaussenot, Annabelle, Julier, Cécile, Cnop, Miriam

المصدر: European journal of endocrinology, 184 (3

مصطلحات موضوعية: Enseignement des sciences, Biologie, Biologie moléculaire, Biologie cellulaire, Biologie générale, Diabétologie, Adolescent, Adult, Age Factors, Animals, Apoptosis -- genetics, Cells, Cultured, Diabetes Mellitus, Type 1 -- genetics -- metabolism, Female, HSP40 Heat-Shock Proteins -- genetics, Humans, Insulin-Secreting Cells -- metabolism -- physiology, Loss of Function Mutation, Male, Mice, Mitochondria -- metabolism -- pathology, Pedigree, Rats, Syndrome

وصف الملف: 2 full-text file(s): application/vnd.openxmlformats-officedocument.wordprocessingml.document | application/pdf

العلاقة: uri/info:doi/10.1530/EJE-20-0636; uri/info:pii/EJE-20-0636; uri/info:pmid/33486469; uri/info:scp/85102222322; https://dipot.ulb.ac.be/dspace/bitstream/2013/326382/4/Shared_last_and_corresponding_authorship.docxTest; https://dipot.ulb.ac.be/dspace/bitstream/2013/326382/3/DNAJC3.pdfTest; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/326382Test

الإتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/326382Test
https://dipot.ulb.ac.be/dspace/bitstream/2013/326382/4/Shared_last_and_corresponding_authorship.docxTest
https://dipot.ulb.ac.be/dspace/bitstream/2013/326382/3/DNAJC3.pdfTest

المؤلفون: Shah, Sweta, Dooms, Marc Marie, Amaral-Garcia, Sofia, Igoillo Esteve, Mariana

المصدر: Frontiers in Pharmacology, 12

مصطلحات موضوعية: Sciences bio-médicales et agricoles, Sciences biomédicales, Sciences pharmaceutiques, amyotrophic lateral sclerosis, drug repurposing, European Medicines Agency (EMA), Food and Drug Administration (FDA, US), Friedreich’s ataxia, Huntington’s disease, orphanet, wolfram syndrome

وصف الملف: 1 full-text file(s): application/pdf

العلاقة: uri/info:doi/10.3389/fphar.2021.768023; uri/info:scp/85122207205; https://dipot.ulb.ac.be/dspace/bitstream/2013/342060/1/doi_325704.pdfTest; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/342060Test

الإتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/342060Test

المؤلفون: Arroyo, Maria Nicol, Cnop, Miriam, Green, Jonathan, Igoillo Esteve, Mariana

المصدر: International journal of molecular sciences, 22 (2

مصطلحات موضوعية: Sciences bio-médicales et agricoles, insulin resistance, obesity, pancreatic β-cells, tRNA, tRNA fragments, tRNA modifications, type 2 diabetes

وصف الملف: 1 full-text file(s): application/pdf

العلاقة: uri/info:doi/10.3390/ijms22020496; uri/info:pii/ijms22020496; uri/info:pmid/33419045; uri/info:scp/85099157279; uri/info:pmcid/PMC7825315; https://dipot.ulb.ac.be/dspace/bitstream/2013/326379/1/doi_310023.pdfTest; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/326379Test

الإتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/326379Test