المؤلفون: Peter R. Corridon

المصدر: Frontiers in Physiology, Vol 14 (2023)

مصطلحات موضوعية: IDH2 [isocitrate dehydrogenase 2 (NADP+) and mitochondrial], gene delivery, acute kidney injury, hydrodynamic injections, ischemia-reperfusion injury (I/R), hydrodynamic gene delivery, Physiology, QP1-981

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fphys.2023.1024238/fullTest; https://doaj.org/toc/1664-042XTest

الوصول الحر: https://doaj.org/article/599c7086c6c840ffb2be379435e0b8dcTest

المؤلفون: Riemann, Anne, Rauschner, Mandy, Gießelmann, Marina, Reime, Sarah, Haupt, Verena, Thews, Oliver

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 5, Pp 450-458 (2019)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: Male, Original article, Scd2, stearoyl-CoA desaturase 2, Epithelial-Mesenchymal Transition, Snai1, snail family transcriptional repressor 1, Twist1, twist family bHLH transcription factor 1, lcsh:RC254-282, Cell Adhesion, Animals, Humans, Vimentin, Fh, fumarate hydratase, Acsl1, acyl-CoA synthetase long-chain family member 1, Zeb2, zinc finger E-box binding homeobox 2, Zeb1, zinc finger E-box binding homeobox 1, Cadherins, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Gpi, glucose-6-phosphate isomerase, Rats, NGS, next-generation sequencing, Gene Expression Regulation, Neoplastic, Idh2, isocitrate dehydrogenase 2, Scd1, stearoyl-CoA desaturase 1, MIBG, meta-iodobenzylguanidine, Acidosis, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d204e64efdc5d7dd32703734bfd194d2Test
http://www.sciencedirect.com/science/article/pii/S1476558618306705Test

المؤلفون: Stephen K. Burley

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, 3D, Three-dimensional/Three dimensions, D3R, Drug Design Data Resource, Protein Conformation, Druggability, Protein Data Bank (RCSB PDB), Information Storage and Retrieval, PDBj, Protein Data Bank Japan, RCB Protein Data Bank, drug discovery and development, Biochemistry, US, United States, Drug Delivery Systems, Drug Discovery, structural biology, Databases, Protein, structure-guided drug discovery, FAIR principles, Drug discovery, mmCIF, Macromolecular Crystallographic Information File, computer.file_format, FAIR, Findability, Accessibility, Interoperability, and Reusability, BMRB, Biological Magnetic Resonance Data Bank, Small molecule, open-access biodata resource, Abl, Abelson Proto-oncogene 1, Nonreceptor Tyrosine Kinase, ADME, Absorption-Distribution-Metabolism-Excretion, PDBe, Protein Data Bank in Europe, wwPDB, Worldwide Protein Data Bank, drug target validation, HIV, Human Immunodeficiency Virus, 3DEM, Three-dimensional Electron Microscopy, Src, Proto-oncogene Sarcoma Tyrosine-protein Kinase, CDK4, Cyclin-dependent Kinase 4, PH+, Philadelphia Chromosome Positive, Computational biology, NMR, Nuclear Magnetic Resonance, Small Molecule Libraries, 03 medical and health sciences, Drug Development, Form and function, Protein Data Bank, PDB, Protein Data Bank, protein structure, PDBx, Protein Data Bank Exchange Data Dictionary, Molecular Biology, Biomedicine, EMDB, Electron Microscopy Data Bank, 030102 biochemistry & molecular biology, business.industry, CDK6, Cyclin-dependent Kinase 6, JBC Reviews, Proteins, RCSB, Research Collaboratory for Structural Bioinformatics, RNA, Ribonucleic Acid, Cell Biology, OneDep, Unified wwPDB System for Deposition, Biocuration, and Validation, FDA, Food and Drug Administration, QT Interval, Electrocardiogram Q-wave to T-wave Interval, 030104 developmental biology, Structural biology, PDB50, ID, Identifier, GIST, Gastrointestinal Stromal Tumor, IDH2, Isocitrate Dehydrogenase 2, MX, Macromolecular Crystallography, business, computer, CML, Chronic Myelogenous Leukemia, DNA, Deoxyribonucleic Acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a21b9caf1386840870f7909454ae2d5Test
https://pubmed.ncbi.nlm.nih.gov/33744282Test

المؤلفون: Daniel Monleon, Pedro Roldán, Lara Navarro, Teresa San-Miguel, Javier Megías, Concha López-Ginés, Lisandra Muñoz-Hidalgo, Miguel Cerdá-Nicolás

المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 1, Pp 10-21 (2020)

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Biopsy, L-amp GB, EGFR-low amplified glioblastoma, medicine.disease_cause, wt, wildtype, MYBPC3, myosin-binding protein C, 0302 clinical medicine, HIC1, hypermethylated in cancer 1, Gene duplication, In Situ Hybridization, Fluorescence, IDH2, isocitrate dehydrogenase 2, Mutation, RB-pat, RB signaling pathway, EGFRvIII, epidermal growth factor receptor variant number III, PAH, phenylalanine hydroxylase, GBM, glioblastoma, IDH-wildtype (glioblastoma multiforme, primary glioblastoma), ANOVA, ANalysis Of VAriance, N-amp GB, EGFR-no amplified glioblastoma, Middle Aged, CDKN2A, cyclin-dependent kinase inhibitor 2A, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Prognosis, Primary tumor, Immunohistochemistry, H-amp GB, EGFR-high amplified glioblastoma, ErbB Receptors, TKR-pat, tyrosine-kinase receptors signaling pathway, 030220 oncology & carcinogenesis, Disease Progression, CDK6, cyclin-dependent kinase 6, CDH1, Cadherin 1, Female, CREM, cAMP response element modulator, IHC, immunohistochemistry, Adult, Original article, DNA Copy Number Variations, CDKN1B, cyclin-dependent kinase inhibitor 1B, Biology, RARB, retinoic acid receptor beta, CNS, central nervous system, lcsh:RC254-282, IDH1, isocitrate dehydrogenase 1, BCL2, B-cell cll/ lymphoma 2, CNAs, copy number algerations, WHO, World Health Organization, 03 medical and health sciences, Young Adult, p53-pat, p53 signaling pathway, medicine, Biomarkers, Tumor, TMA, tissue microarray, PTEN, Humans, Protein kinase B, PI3K/AKT/mTOR pathway, Survival analysis, Aged, Genetic heterogeneity, Gene Amplification, GFAP, glial fibrillary acidic protein, MLPA, multiplex ligation-dependent probe amplification, medicine.disease, FISH, fluorescence in situ hibridization, Survival Analysis, CDKN2B, cyclin-dependent kinase inhibitor 2B, PTEN, phosphatase and tensin homolog, EGFR, epidermal growth factor receptor, CNV-load, load of copy number variations, 030104 developmental biology, PARK2, parkin, Cancer research, biology.protein, TCGA, The Cancer Genome Atlas, LARGE1, acetylglucosaminyltransferase-like protein 1, Glioblastoma, CHD7, Chromodomain Helicase DNA Binding Protein 7, DAPI, 4′,6-diamidino-2-phenylindole

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071c5ffa07d10f257ddbf1bca2c7a8eeTest
https://pubmed.ncbi.nlm.nih.gov/31751860Test

المؤلفون: Munehiro Kitada, Shinji Kume, Ai Takeda-Watanabe, Keizo Kanasaki, Daisuke Koya

المصدر: Clinical Science (London, England : 1979)

مصطلحات موضوعية: Aging, IGF, insulin-like growth factor, PARP, poly(ADP-ribose) polymerase, Review Article, Bioinformatics, TNF-α, tumour necrosis factor α, Diabetic nephropathy, PTP1B, protein tyrosine phosphatase 1B, chemistry.chemical_compound, Sirtuin 1, FOXO, forkhead box O, Sirtuin 3, SIRT1 (sirtuin 1), Sirtuins, Atg, autophagy-related gene, Diabetic Nephropathies, AT1R, angiotensin type 1 receptor, TGF, transforming growth factor, ICAM-1, intercellular adhesion molecule 1, Kidney, WFR, Wistar fatty diabetic rat, AngII, angiotensin II, eNOS, endothelial NO synthase, General Medicine, PGC-1α, PPAR-γ co-activator-1α, MCP-1, monocyte chemotactic protein-1, SIRT1 etc., sirtuin 1 etc., SNP, single nucleotide polymorphism, HIF, hypoxia-inducible factor, sirtuin, Idh2, isocitrate dehydrogenase 2, BMAL1, brain and muscle ARNT (aryl hydrocarbon receptor nuclear translocator)-like 1, medicine.anatomical_structure, Sirtuin, CRP, C-reactive protein, IRS, insulin receptor substrate, Advanced glycation end-product, Kidney Diseases, Bnip3, BCL2/adenovirus E1V 19-kDa interacting protein 3, PPAR, peroxisome-proliferator-activated receptor, SREBP, sterol-regulatory-element-binding protein, SIRT6, medicine.medical_specialty, Calorie restriction, H3K9me3, H3K9 trimethylation, NF-κB, nuclear factor-κB, S6, mTOR, mammalian target of rapamycin, Biology, α-ENaC, epithelial Na+ channel α-subunit, S4, ER, endoplasmic reticulum, FXR, farnesoid X receptor, ROS, reactive oxygen species, RAS, renin–angiotensin system, Internal medicine, Diabetes mellitus, PKC, protein kinase C, medicine, CR, calorie restriction, Animals, Humans, Sir2, silent information regulator 2, UUO, unilateral ureteral obstruction, Caloric Restriction, Mn-SOD, manganese superoxide dismutase, diabetic nephropathy, CKD, chronic kidney disease, H3K9, histone H3 Lys9, medicine.disease, PER2, Period 2, Angiotensin II, LC3, light chain 3, VCAM-1, vascular cell adhesion protein 1, AMPK, AMP-activated protein kinase, Endocrinology, AGE, advanced glycation end-product, chemistry, COX2, cyclo-oxygenase 2, biology.protein, LXR, liver X receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4055ae0b65db646f19c8a4a1d9c7496Test
https://doi.org/10.1042/cs20120190Test