المؤلفون: Hämäläinen, Riikka H., Landoni, Juan C., Ahlqvist, Kati J., Goffart, Steffi, Ryytty, Sanna, Rahman, M. Obaidur, Brilhante, Virginia, Icay, Katherine, Hautaniemi, Sampsa, Wang, Liya, Laiho, Marikki, Suomalainen, Anu

المساهمون: STEMM - Stem Cells and Metabolism Research Program, Research Programs Unit, University of Helsinki, HUSLAB, Research Program in Systems Oncology, Sampsa Hautaniemi / Principal Investigator, Bioinformatics, Department of Biochemistry and Developmental Biology, HUS Helsinki and Uusimaa Hospital District, Neurologian yksikkö, Helsinki University Hospital Area, Neuroscience Center

مصطلحات موضوعية: PHENOTYPES, MUTATIONS, DISTINCT, MICE, 3111 Biomedicine, 1182 Biochemistry, cell and molecular biology, 3112 Neurosciences

وصف الملف: application/pdf

العلاقة: Hämäläinen , R H , Landoni , J C , Ahlqvist , K J , Goffart , S , Ryytty , S , Rahman , M O , Brilhante , V , Icay , K , Hautaniemi , S , Wang , L , Laiho , M & Suomalainen , A 2020 , ' Reply to : Proofreading deficiency in mitochondrial DNA polymerase does not affect total dNTP pools in mouse embryos ' , Nature metabolism , vol. 2 , no. 8 , pp. 676-677 . https://doi.org/10.1038/s42255-020-0265-yTest; ORCID: /0000-0002-7749-2694/work/80576245; ORCID: /0000-0002-0318-6707/work/80577591; 58886eb0-f009-4a46-9cef-b81b18199feb; http://hdl.handle.net/10138/326256Test; 000561178600009

الإتاحة: http://hdl.handle.net/10138/326256Test

المؤلفون: Hämäläinen, Riikka H., Landoni, Juan C., Ahlqvist, Kati J., Goffart, Steffi, Ryytty, Sanna, Rahman, M. Obaidur, Brilhante, Virginia, Icay, Katherine, Hautaniemi, Sampsa, Wang, Liya, Laiho, Marikki, Suomalainen, Anu

المصدر: Nature Metabolism ; volume 2, issue 8, page 793-793 ; ISSN 2522-5812

مصطلحات موضوعية: Cell Biology, Physiology (medical), Endocrinology, Diabetes and Metabolism, Internal Medicine

الإتاحة: https://doi.org/10.1038/s42255-020-0255-0Test
https://www.nature.com/articles/s42255-020-0255-0.pdfTest
https://www.nature.com/articles/s42255-020-0255-0Test

المؤلفون: Icay, Katherine, Liu, Chengyu, Hautaniemi, Sampsa

المساهمون: Research Programs Unit, Genome-Scale Biology (GSB) Research Program, University of Helsinki, Bioinformatics

مصطلحات موضوعية: SEROUS OVARIAN-CANCER, CARCINOMA, NETWORK, TOOL, 3111 Biomedicine

وصف الملف: application/pdf

العلاقة: This work was supported financially by the Academy of Finland (projects 305087 and 284598), the Sigrid Juselius Foundation and Finnish Cancer Association. The results published here are in whole based upon data generated by The Cancer Genome Atlas managed by the NCI and NHGRI. Information about TCGA can be found at http://cancergenome.nih.govTest. Computing resources from CSC- IT Center for Science Ltd. are gratefully acknowledged.; Icay , K , Liu , C & Hautaniemi , S 2018 , ' Dynamic visualization of multi-level molecular data : The Director package in R ' , Computer Methods and Programs in Biomedicine , vol. 153 , pp. 129-136 . https://doi.org/10.1016/j.cmpb.2017.10.013Test; ORCID: /0000-0002-7749-2694/work/39925551; 85032855477; 668af5fd-9b26-4889-810c-c868dfbf08d6; http://hdl.handle.net/10138/298158Test; 000416507300014

الإتاحة: http://hdl.handle.net/10138/298158Test

المؤلفون: Pekkonen, Pirita, Alve, Sanni, Balistreri, Giuseppe, Gramolelli, Silvia, Tatti-Bugaeva, Olga, Paatero, Ilkka, Niiranen, Otso, Tuohinto, Krista, Perala, Nina, Taiwo, Adewale, Zinovkina, Nadezhda, Repo, Pauliina, Icay, Katherine, Ivaska, Joanna, Saharinen, Pipsa, Hautaniemi, Sampsa, Lehti, Kaisa, Ojala, Paivi M.

المساهمون: Research Programs Unit, Translational Cancer Biology (TCB) Research Programme, Genome-Scale Biology (GSB) Research Program, Pipsa Ilona Saharinen / Principal Investigator, Sampsa Hautaniemi / Principal Investigator, Bioinformatics, Kaisa Irene Lehti / Principal Investigator, Päivi Ojala / Research director

مصطلحات موضوعية: TO-MESENCHYMAL TRANSITION, TUMOR PROGRESSION, NODE METASTASIS, CELL-ADHESION, CANCER, METALLOPROTEINASES, EXPRESSION, PLATFORM, VESSELS, CCR7, 3111 Biomedicine

وصف الملف: application/pdf

العلاقة: Terveyden Tutkimuksen Toimi-kunta 307366 Johanna Ivaska Pipsa Saharinen Paivi M Ojala; Pekkonen , P , Alve , S , Balistreri , G , Gramolelli , S , Tatti-Bugaeva , O , Paatero , I , Niiranen , O , Tuohinto , K , Perala , N , Taiwo , A , Zinovkina , N , Repo , P , Icay , K , Ivaska , J , Saharinen , P , Hautaniemi , S , Lehti , K & Ojala , P M 2018 , ' Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and beta 1-integrin activation ' , eLife , vol. 7 , 32490 . https://doi.org/10.7554/eLife.32490Test; ORCID: /0000-0002-7749-2694/work/44998566; ORCID: /0000-0002-9257-9376/work/90907025; 85049593514; cba1f277-1169-4721-b243-c8325363fca1; http://hdl.handle.net/10138/235268Test; 000431114900001

الإتاحة: http://hdl.handle.net/10138/235268Test

المؤلفون: Leivonen, Suvi-Katri, Icay, Katherine, Jäntti, Kirsi, Siren, Ilari, Liu, Chengyu, Alkodsi, Amjad, Cervera, Alejandra, Ludvigsen, Maja, Hamilton-Dutoit, Stephen Jacques, d'Amore, Francesco, Karjalainen-Lindsberg, Marja-Liisa, Delabie, Jan, Holte, Harald, Lehtonen, Rainer, Hautaniemi, Sampsa, Leppä, Sirpa

المساهمون: Research Programs Unit, Genome-Scale Biology (GSB) Research Program, Sirpa Marianne Leppä / Principal Investigator, Clinicum, Department of Oncology, University of Helsinki, Sampsa Hautaniemi / Principal Investigator, Department of Pathology, Medicum, Bioinformatics, HUS Comprehensive Cancer Center

مصطلحات موضوعية: CHEMOTHERAPY PLUS RITUXIMAB, NON-HODGKIN-LYMPHOMA, TUMOR-SUPPRESSOR, TRANSGENIC MICE, IN-VIVO, EXPRESSION, CANCER, MALIGNANCIES, PROGNOSIS, GROWTH, 3122 Cancers, 3111 Biomedicine

وصف الملف: application/pdf

العلاقة: The study was supported by grants from the Academy of Finland (SH), Finnish Cancer Societies (SL, SH), Sigrid Juselius Foundation (SL, SH), University of Helsinki (SL), and Helsinki University Hospital (SL).; Leivonen , S-K , Icay , K , Jäntti , K , Siren , I , Liu , C , Alkodsi , A , Cervera , A , Ludvigsen , M , Hamilton-Dutoit , S J , d'Amore , F , Karjalainen-Lindsberg , M-L , Delabie , J , Holte , H , Lehtonen , R , Hautaniemi , S & Leppä , S 2017 , ' MicroRNAs regulate key cell survival pathways and mediate chemosensitivity during progression of diffuse large B- cell lymphoma ' , Blood cancer journal , vol. 7 , 654 . https://doi.org/10.1038/s41408-017-0033-8Test; ORCID: /0000-0002-7749-2694/work/40898630; ORCID: /0000-0002-8265-511X/work/40900641; ORCID: /0000-0002-8343-0318/work/40901791; ORCID: /0000-0003-3224-0757/work/42416257; ORCID: /0000-0003-3528-4683/work/40902478; 85038862533; a62b4369-0aaa-44b9-bc48-e584e430569c; http://hdl.handle.net/10138/231265Test; 000418945800008

الإتاحة: http://hdl.handle.net/10138/231265Test

المؤلفون: Pekkonen, Pirita, Alve, Sanni, Balistreri, Giuseppe, Gramolelli, Silvia, Tatti-Bugaeva, Olga, Paatero, Ilkka, Niiranen, Otso, Tuohinto, Krista, Perälä, Nina, Taiwo, Adewale, Zinovkina, Nadezhda, Repo, Pauliina, Icay, Katherine, Ivaska, Johanna, Saharinen, Pipsa, Hautaniemi, Sampsa, Lehti, Kaisa, Ojala, Päivi M

المساهمون: Terveyden Tutkimuksen Toimikunta, Finnish Cancer Foundation, Sigrid Juséliuksen Säätiö, University of Helsinki, University of Helsinki Foundation, Suomen Lääketieteen Säätiö, Emil Aaltosen Säätiö

المصدر: eLife ; volume 7 ; ISSN 2050-084X

الإتاحة: https://doi.org/10.7554/elife.32490Test
https://cdn.elifesciences.org/articles/32490/elife-32490-v2.pdfTest
https://cdn.elifesciences.org/articles/32490/elife-32490-v2.xmlTest
https://elifesciences.org/articles/32490Test

المؤلفون: Leivonen, Suvi-Katri, Icay, Katherine, Jäntti, Kirsi, Siren, Ilari, Liu, Chengyu, Alkodsi, Amjad, Cervera, Alejandra, Ludvigsen, Maja, Hamilton-Dutoit, Stephen Jacques, d’Amore, Francesco, Karjalainen-Lindsberg, Marja-Liisa, Delabie, Jan, Holte, Harald, Lehtonen, Rainer, Hautaniemi, Sampsa, Leppä, Sirpa

المصدر: Blood Cancer Journal ; volume 7, issue 12 ; ISSN 2044-5385

مصطلحات موضوعية: Oncology, Hematology

الإتاحة: https://doi.org/10.1038/s41408-017-0033-8Test
https://www.nature.com/articles/s41408-017-0033-8.pdfTest
https://www.nature.com/articles/s41408-017-0033-8Test

المؤلفون: Icay, Katherine, Chen, Ping, Cervera Taboada, Alejandra, Rantanen, Ville, Lehtonen, Rainer, Hautaniemi, Sampsa

المساهمون: Research Programs Unit, Sampsa Hautaniemi / Principal Investigator, Genome-Scale Biology (GSB) Research Program, Department of Biochemistry and Developmental Biology, Medicum, Lauri Antti Aaltonen / Principal Investigator, Bioinformatics

مصطلحات موضوعية: Sequencing, Integration, miRNA, totalRNA, RNA, Breast cancer, BREAST-CANCER, SEQ DATA, DIFFERENTIAL EXPRESSION, SIGNALING PATHWAY, GENE-EXPRESSION, QUALITY-CONTROL, READ ALIGNMENT, QUANTIFICATION, MODULATION, 3111 Biomedicine

وصف الملف: application/pdf

العلاقة: This work was supported financially by the Academy of Finland (Center of Excellence in Cancer Genetics Research), the Sigrid Juselius Foundation, Finnish Cancer Associations, and Doctoral Programme in Biomedicine (KI, AC). Computational resources from CSC - IT Center for Science are gratefully acknowledged. We thank Erkka Valo for his contributions to component development in SePIA. The results published here are in part based upon data generated by The Cancer Genome Atlas managed by the NCI and NHGRI. Information about TCGA can be found at http://cancergenome.nih.govTest.; Icay , K , Chen , P , Cervera Taboada , A , Rantanen , V , Lehtonen , R & Hautaniemi , S 2016 , ' SePIA : RNA and small RNA sequence processing, integration, and analysis ' , BioData mining , vol. 9 , 20 . https://doi.org/10.1186/s13040-016-0099-zTest; ORCID: /0000-0002-7749-2694/work/29942474; ORCID: /0000-0002-8343-0318/work/29554918; 84974708411; 67094d3f-d56b-46ce-8b39-6397fa4c7490; http://hdl.handle.net/10138/164695Test; 000376843700001

الإتاحة: http://hdl.handle.net/10138/164695Test

المؤلفون: Asikainen, Suvi, Heikkinen, Liisa, Juhila, Juuso Johannes, Holm, Frida, Weltner, Jere, Trokovic, Ras, Mikkola, Milla, Toivonen, Sanna, Balboa, Diego, Lampela, Riina, Icay, Katherine, Tuuri, Timo, Otonkoski, Timo, Wong, Garry, Hovatta, Outi

المساهمون: Research Programme for Molecular Neurology, Research Programs Unit, Children's Hospital, HUS Children and Adolescents

مصطلحات موضوعية: MOUSE ES CELLS, GENE-EXPRESSION, MATURE MICRORNAS, FEEDER CELLS, HUMAN DICER, PLURIPOTENCY, DISCOVERY, MIRNAS, ELEMENTS, MORNAS, 3111 Biomedicine

وصف الملف: application/pdf

العلاقة: This study was supported by Academy of Finland, SA GW TO (http://www.aka.fi/ENGTest); Biocenter Finland, LH (http://www.biocenter.fiTest/); Sigrid Juselius Foundation, SA TO (http://www.sigridjuselius.fi/foundationTest); Swedish Research Council, OH (http://www.vr.se/inenglish.4.12fff4451215cbd83e4800015152.htmlTest). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.; Asikainen , S , Heikkinen , L , Juhila , J J , Holm , F , Weltner , J , Trokovic , R , Mikkola , M , Toivonen , S , Balboa , D , Lampela , R , Icay , K , Tuuri , T , Otonkoski , T , Wong , G & Hovatta , O 2015 , ' Selective MicroRNA-Offset RNA Expression in Human Embryonic Stem Cells ' , PLoS One , vol. 10 , no. 3 , 0116668 . https://doi.org/10.1371/journal.pone.0116668Test; ORCID: /0000-0002-3065-6663/work/66562852; 84926298645; 67835497-ef88-4e19-a180-487b68e33d39; http://hdl.handle.net/10138/160345Test; 000352134700004

الإتاحة: http://hdl.handle.net/10138/160345Test

المؤلفون: Asikainen, Suvi, Heikkinen, Liisa, Juhila, Juuso, Holm, Frida, Weltner, Jere, Trokovic, Ras, Mikkola, Milla, Toivonen, Sanna, Balboa, Diego, Lampela, Riina, Icay, Katherine, Tuuri, Timo, Otonkoski, Timo, Wong, Garry, Hovatta, Outi

مصطلحات موضوعية: microRNAs, miRNA-offset RNAs, RNA sequencing, embryonic stem cells

وصف الملف: application/pdf

العلاقة: PLoS ONE; 10; Asikainen, S., Heikkinen, L., Juhila, J., Holm, F., Weltner, J., Trokovic, R., Mikkola, M., Toivonen, S., Balboa, D., Lampela, R., Icay, K., Tuuri, T., Otonkoski, T., Wong, G., & Hovatta, O. (2015). Selective MicroRNA-Offset RNA Expression in Human Embryonic Stem Cells. PLoS ONE , 10 (3), Article e0116668. https://doi.org/10.1371/journal.pone.0116668Test; CONVID_24712842; TUTKAID_66174; URN:NBN:fi:jyu-201505201923; http://urn.fi/URN:NBN:fi:jyu-201505201923Test

الإتاحة: http://urn.fi/URN:NBN:fi:jyu-201505201923Test