دورية
Side-specific factors for intraoperative hemodynamic instability in laparoscopic adrenalectomy for pheochromocytoma: a comparative study
| العنوان: | Side-specific factors for intraoperative hemodynamic instability in laparoscopic adrenalectomy for pheochromocytoma: a comparative study |
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| المؤلفون: | Habeeb, Tamer A. A. M., Araujo-Castro, Marta, Chiaretti, Massimo, Podda, Mauro, Aiolfi, Alberto, Kryvoruchko, Igor A., Manangi, Mallikarjuna N., Shelat, Vishal, Kalmoush, Abd-Elfattah, Labib, Mohamed Fathy, Elshafey, Mohammed Hassan, Ibrahim, Sameh Mohamed Mahmoud, Abo Alsaad, Mohamed Ibrahim, Elbelkasi, Hamdi, Mansour, Mohamed Ibrahim, Elshahidy, Tamer Mohamed, Heggy, Ibrahim A., Elsayed, Rasha S., Fiad, Alaa A., Yehia, Ahmed M., Yassin, Mahmoud Abdou, Elballat, Mahmoud R., Hebeishy, Mohamed H., AboZeid, Ahmed Khaled, Saleh, Mohamed Adel Ahmed, Hamed, Abd Elwahab M., Abdelghani, Amr A., Mousa, Bassam |
| المصدر: | Surgical Endoscopy; 20240101, Issue: Preprints p1-12, 12p |
| مستخلص: | Background: Adrenalectomy for pheochromocytoma (PHEO) is challenging because of the high risk of intraoperative hemodynamic instability (HDI). This study aimed to compare the incidence and risk factors of intraoperative HDI between laparoscopic left adrenalectomy (LLA) and laparoscopic right adrenalectomy (LRA). Methods: We retrospectively analyzed two hundred and seventy-one patients aged > 18 years with unilateral benign PHEO of any size who underwent transperitoneal laparoscopic adrenalectomy at our hospitals between September 2016 and September 2023. Patients were divided into LRA (N= 122) and LLA (N= 149) groups. Univariate and multivariate logistic regression analyses were used to predict intraoperative HDI. In multivariate analysis for the prediction of HDI, right-sided PHEO, PHEO size, preoperative comorbidities, and preoperative systolic blood pressure were included. Results: Intraoperative HDI was significantly higher in the LRA group than in the LLA (27% vs. 9.4%, p< 0.001). In the multivariate regression analysis, right-sided tumours showed a higher risk of intraoperative HDI (odds ratio [OR] 5.625, 95% confidence interval [CI], 1.147–27.577, p= 0.033). The tumor size (OR 11.019, 95% CI 3.996–30.38, p< 0.001), presence of preoperative comorbidities [diabetes mellitus, hypertension, and coronary heart disease] (OR 7.918, 95% CI 1.323–47.412, p= 0.023), and preoperative systolic blood pressure (OR 1.265, 95% CI 1.07–1.495, p= 0.006) were associated with a higher risk of HDI in both LRA and LLA, with no superiority of one side over the other. Conclusion: LRA was associated with a significantly higher intraoperative HDI than LLA. Right-sided PHEO was a risk factor for intraoperative HDI. |
| قاعدة البيانات: | Supplemental Index |
| تدمد: | 09302794 14322218 |
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| DOI: | 10.1007/s00464-024-10974-w |