نتائج البحث - "Ian Slaymaker"

المصدر: Cell Reports, Vol 34, Iss 10, Pp 108865-(2021)
Slaymaker, I M, Mesa, P, Kellner, M J, Kannan, S, Brignole, E, Koob, J, Feliciano, P R, Stella, S, Abudayyeh, O O, Gootenberg, J S, Strecker, J, Montoya, G & Zhang, F 2019, ' High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage ', Cell Reports, vol. 26, no. 13, pp. 3741-3751.e5 . https://doi.org/10.1016/j.celrep.2019.02.094Test
Cell Reports, Vol 26, Iss 13, Pp 3741-3751.e5 (2019)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c67bbc419cbbb410dcbbc28d92a227Test
http://www.sciencedirect.com/science/article/pii/S2211124721001790Test

5

Base editing: advances and therapeutic opportunities

المؤلفون: Elizabeth M. Porto, Alexis C. Komor, Gene W. Yeo, Ian Slaymaker

المصدر: Nature reviews. Drug discovery, vol 19, iss 12
Nat Rev Drug Discov

مصطلحات موضوعية: 0301 basic medicine, Computational biology, Biology, Polymorphism, Single Nucleotide, Medical and Health Sciences, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Genome editing, Neoplasms, Drug Discovery, Genetics, Humans, Disease, Muscular Dystrophy, Pharmacology & Pharmacy, Polymorphism, Hearing Loss, Pharmacology, Gene Editing, Liver Diseases, Human Genome, Genetic variants, RNA, Neoplasms therapy, General Medicine, Single Nucleotide, Biological Sciences, Precision medicine, Base (topology), Duchenne, Muscular Dystrophy, Duchenne, 030104 developmental biology, Good Health and Well Being, chemistry, 030220 oncology & carcinogenesis, Single point, CRISPR-Cas Systems, DNA

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664d67bacceb03adc158e8351d14cf50Test
https://escholarship.org/uc/item/2s52m1ksTest

6

Conversion of HbS to Hb G-Makassar By Adenine Base Editing Is Compatible with Normal Hemoglobin Function

المصدر: Blood. 138:951-951

مصطلحات موضوعية: Stereochemistry, Chemistry, Immunology, Normal hemoglobin, Cell Biology, Hematology, Base (exponentiation), Biochemistry, Function (biology), Hb G-Makassar

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::87fc38ac083cf1875f7dd8e0c3007d56Test
https://doi.org/10.1182/blood-2021-150922Test

7

CRISPR–Cas9 Mediated DNA Unwinding Detected Using Site-Directed Spin Labeling

المؤلفون: Rosa Di Felice, Carolina Reyes, Wei Jiang, Narin S. Tangprasertchai, Ian Slaymaker, Xiaojun Zhang, Remo Rohs, Peter Z. Qin

المصدر: ACS chemical biology (Online) 12 (2017): 1489–1493. doi:10.1021/acschembio.6b01137
info:cnr-pdr/source/autori:Tangprasertchai N.S.; Di Felice R.; Zhang X.; Slaymaker I.M.; Vazquez Reyes C.; Jiang W.; Rohs R.; Qin P.Z./titolo:CRISPR-Cas9 Mediated DNA Unwinding Detected Using Site-Directed Spin Labeling/doi:10.1021%2Facschembio.6b01137/rivista:ACS chemical biology (Online)/anno:2017/pagina_da:1489/pagina_a:1493/intervallo_pagine:1489–1493/volume:12

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::311787c8532560145360d5a3310a76baTest
https://doi.org/10.1021/acschembio.6b01137Test

8

Adenine Base Editing of the Sickle Allele in CD34+ Hematopoietic Stem and Progenitor Cells Eliminates Hemoglobin S

المؤلفون: Giuseppe Ciaramella, Adam J. Hartigan, Calvin Lee, Alexander Liquori, Bo Yan, David A. Born, Tanggis Bohnuud, S. Haihua Chu, Jeffrey Marshall, Jennifer Olins, Daisy Lam, Luis A. Barrera, Ian Slaymaker, Jeremy Decker, Bob Gantzer, Nicole M. Gaudelli, Michael S. Packer, Scott Haskett

المصدر: Blood. 136:47-47

مصطلحات موضوعية: Cellular differentiation, Genetic enhancement, Immunology, Hemoglobin variants, Cell Biology, Hematology, Biology, Biochemistry, Virology, Haematopoiesis, Erythropoiesis, Globin, Progenitor cell, Stem cell

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c3e1e9774b05d45b7749d120fbc98477Test
https://doi.org/10.1182/blood-2020-141805Test

9

Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits

المؤلفون: Gerald R. Crabtree, Niels R. Weisbach, Sabina Sood, Jitendra Sharma, Ashwin S. Shetty, Ian Slaymaker, Hannah R. Kempton, Mitul Desai, Randall Jeffrey Platt, Yang Zhou, Guoping Feng, Jinah Kim, Feng Zhang

المساهمون: Broad Institute of MIT and Harvard, Massachusetts Institute of Technology. Department of Biological Engineering, Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences, Picower Institute for Learning and Memory, Platt, Randall Jeffrey, Zhou, Yang, Slaymaker, Ian, Kim, Jinah, Sharma, Jitendra, Desai, Mitul, Sood, Sabina, Kempton, Hannah R., Feng, Guoping, Zhang, Feng

المصدر: Elsevier
Cell Reports, Vol 19, Iss 2, Pp 335-350 (2017)
Cell Reports, 19 (2)

مصطلحات موضوعية: 0301 basic medicine, Autism Spectrum Disorder, Nucleus accumbens, Medium spiny neuron, Article, General Biochemistry, Genetics and Molecular Biology, Germline, Histones, Mice, 03 medical and health sciences, medicine, Animals, Humans, Wnt Signaling Pathway, lcsh:QH301-705.5, Germ-Line Mutation, Genetics, biology, Adeno-associated virus, Autism spectrum disorder, Behavior, Cas9 knockin mouse, ChIP-seq, CRISPR, MRI, Neocortical development, Physiology, RNA-seq, Molecular pathology, Wnt signaling pathway, Gene Expression Regulation, Developmental, medicine.disease, Phenotype, Chromatin, Corpus Striatum, Megalencephaly, 3. Good health, DNA-Binding Proteins, Disease Models, Animal, 030104 developmental biology, Histone, lcsh:Biology (General), biology.protein, Neuroscience

وصف الملف: application/pdf; application/application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a838d0ea14436479422ed40cf42e85cTest
https://orcid.org/0000-0003-2782-2509Test

10

The 1.8-Å Crystal Structure of the N-Terminal Domain of an Archaeal MCM as a Right-Handed Filament

المؤلفون: Yang Fu, Junfeng Wang, Xiaojiang S. Chen, Ganggang Wang, Ian Slaymaker

المصدر: Journal of Molecular Biology. 426:1512-1523

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f601241c6f8c47669258731d09957a9Test
https://doi.org/10.1016/j.jmb.2013.12.025Test

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