المؤلفون: Castranio, Emilie, Hasel, Philip, Haure-Mirande, Jean-Vianney, Ramirez Jimenez, Angie, Hamilton, B, Kim, Rachel, Glabe, Charles, Wang, Minghui, Zhang, Bin, Gandy, Sam, Liddelow, Shane, Ehrlich, Michelle

المصدر: Alzheimers and Dementia. 19(6)

مصطلحات موضوعية: Alzheimers disease, Inpp5d, SHIP1, cystatin F, microglia, oligomer, spatial transcriptomics, Mice, Humans, Animals, Infant, Alzheimer Disease, Microglia, Mice, Transgenic, Plaque, Amyloid, Disease Models, Animal, Amyloid beta-Peptides, Phosphatidylinositol-3, 4, 5-Trisphosphate 5-Phosphatases

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1pg9m9zkTest

المؤلفون: Gizem Terzioglu, Tracy L. Young-Pearse

المصدر: Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-18 (2023)

مصطلحات موضوعية: NLRP3 inflammasome, SHIP1, INPP5D, Alzheimer’s Disease, Inflammation, Phosphoinositide signaling, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1750-1326Test

الوصول الحر: https://doaj.org/article/455c78a0745140dc96b056787c1a1d90Test

المؤلفون: Hongyu Li, Xiao Yu

المصدر: Autophagy Reports, Vol 2, Iss 1 (2023)

مصطلحات موضوعية: anti-malarial immunity, inpp5d, irf3, selective autophagy, type i interferon, Cytology, QH573-671

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2769-4127Test

الوصول الحر: https://doaj.org/article/db1ccc3427a74a67a5b5f1df99ed3843Test

المؤلفون: Cynthia D. Jesudason, Emily R. Mason, Shaoyou Chu, Adrian L. Oblak, June Javens‐Wolfe, Mustapha Moussaif, Greg Durst, Philip Hipskind, Daniel E. Beck, Jiajun Dong, Ovini Amarasinghe, Zhong‐Yin Zhang, Adam K. Hamdani, Kratika Singhal, Andrew D. Mesecar, Sarah Souza, Marlene Jacobson, Jerry Di Salvo, Disha M. Soni, Murugesh Kandasamy, Andrea R. Masters, Sara K Quinney, Suzanne Doolen, Hasi Huhe, Stacey J. Sukoff Rizzo, Bruce T. Lamb, Alan D. Palkowitz, Timothy I. Richardson

المصدر: Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 9, Iss 4, Pp n/a-n/a (2023)

مصطلحات موضوعية: cellular thermal shift assay (CETSA), INPP5D, pharmacokinetics, phenotypic high‐content imaging assay, SHIP1, SHIP1 inhibitors, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2352-8737Test

الوصول الحر: https://doaj.org/article/4d6f6a10135b4cdbb5e5fc4dd51947a7Test

المؤلفون: Fernandes, S., Srivastava, N., Pedicone, C., Sudan, R., Luke, E. A., Dungan, O. M., Pacherille, A., Meyer, S. T., Dormann, S., Schurmans, Stéphane, Jacobsen, E., Chisholm, J. D., Kerr, W. G.

المصدر: iScience (2023)

مصطلحات موضوعية: obesity, phosphoinositide, 5-phosphatase, Ship1, Ship2, Inppl1, eosinophil, Inpp5D, Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire

العلاقة: urn:issn:2589-0042; https://orbi.uliege.be/handle/2268/299930Test; info:hdl:2268/299930; https://orbi.uliege.be/bitstream/2268/299930/1/ObesitypanSHIPi.Published_.pdfTest; scopus-id:2-s2.0-85147818779

الإتاحة: https://doi.org/10.1016/j.isci.2023.106071Test
https://orbi.uliege.be/handle/2268/299930Test
https://orbi.uliege.be/bitstream/2268/299930/1/ObesitypanSHIPi.Published_.pdfTest

المؤلفون: Diana J. Zajac, James Simpson, Eric Zhang, Ishita Parikh, Steven Estus

المصدر: Genes; Volume 14; Issue 3; Pages: 763

مصطلحات موضوعية: INPP5D, SHIP1, Alzheimer’s disease, next-generation sequencing, allelic expression imbalance, single nucleotide polymorphism, genetics, microglia

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Molecular Genetics and Genomics; https://dx.doi.org/10.3390/genes14030763Test

الإتاحة: https://doi.org/10.3390/genes14030763Test

المؤلفون: Jesudason, Cynthia D., Mason, Emily R., Chu, Shaoyou, Oblak, Adrian L., Javens-Wolfe, June, Moussaif, Mustapha, Durst, Greg, Hipskind, Philip, Beck, Daniel E., Dong, Jiajun, Amarasinghe, Ovini, Zhang, Zhong-Yin, Hamdani, Adam K., Singhal, Kratika, Mesecar, Andrew D., Souza, Sarah, Jacobson, Marlene, Di Salvo, Jerry, Soni, Disha M., Kandasamy, Murugesh, Masters, Andrea R., Quinney, Sara K., Doolen, Suzanne, Huhe, Hasi, Sukoff Rizzo, Stacey J., Lamb, Bruce T., Palkowitz, Alan D., Richardson, Timothy I.

المساهمون: Medicine, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Cellular thermal shift assay (CETSA), INPP5D, Pharmacokinetics, Phenotypic high‐content imaging assay, SHIP1 inhibitors

وصف الملف: application/pdf

العلاقة: Alzheimer’s & Dementia: Translational Research & Clinical Interventions; Jesudason CD, Mason ER, Chu S, et al. SHIP1 therapeutic target enablement: Identification and evaluation of inhibitors for the treatment of late-onset Alzheimer's disease. Alzheimers Dement (N Y). 2023;9(4):e12429. Published 2023 Nov 17. doi:10.1002/trc2.12429; https://hdl.handle.net/1805/39904Test

الإتاحة: https://doi.org/10.1002/trc2.12429Test
https://hdl.handle.net/1805/39904Test

المؤلفون: Soni, Disha M, Lin, Peter Bor-Chian, Lee-Gosselin, Audrey, Lloyd, Christopher D, Mason, Emily, Ingraham, Cynthia M, Perkins, Abigail, Moutinho, Miguel, Lamb, Bruce T, Chu, Shaoyou, Oblak, Adrian L

المصدر: Alzheimers Dement ; ISSN:1552-5279

مصطلحات موضوعية: Alzheimer's disease, Inpp5d, Inpp5d haplodeficiency, PS19, microglia, tau pathology

العلاقة: https://doi.org/10.1002/alz.14078Test; https://pubmed.ncbi.nlm.nih.gov/38923171Test

الإتاحة: https://doi.org/10.1002/alz.14078Test
https://pubmed.ncbi.nlm.nih.gov/38923171Test

المؤلفون: Fernandes, Sandra, Srivastava, Neetu, Sudan, Raki, Middleton, Frank A, Shergill, Amandeep K, Ryan, James C, Kerr, William G

المصدر: Frontiers in Immunology. 9(MAY)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Genetics, Crohn's Disease, Digestive Diseases, Autoimmune Disease, Inflammatory Bowel Disease, Clinical Research, 2.1 Biological and endogenous factors, Aetiology, Oral and gastrointestinal, Alleles, Animals, Autophagy-Related Proteins, Biomarkers, Computational Biology, Crohn Disease, Disease Models, Animal, Disease Susceptibility, Exons, Gene Expression Profiling, Gene Expression Regulation, Humans, Inflammatory Bowel Diseases, Leukocytes, Mononuclear, Lymphocyte Count, Mice, Mice, Transgenic, Mutation, Phosphatidylinositol-3, 4, 5-Trisphosphate 5-Phosphatases, Proteasome Endopeptidase Complex, Severity of Illness Index, T-Lymphocytes, Exome Sequencing, SHIP1, Crohn's disease, T cells, human inflammatory bowel disease, INPP5D, ATG16L1, fusion transcript, Crohn’s disease, Immunology, Medical Microbiology, Biochemistry and cell biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/544276fgTest

المؤلفون: Dabin, Luke C, Kersey, Holly, Kim, Byungwook, Acri, Dominic J, Sharify, Daniel, Lee-Gosselin, Audrey, Lasagna-Reeves, Cristian A, Oblak, Adrian L, Lamb, Bruce T, Kim, Jungsu

المصدر: Alzheimers Dement ; ISSN:1552-5279

مصطلحات موضوعية: Alzheimer, Inpp5d, dementia, microglia, network analysis, neurodegeneration, sex difference, single‐cell, transcriptomics

العلاقة: https://doi.org/10.1002/alz.13901Test; https://pubmed.ncbi.nlm.nih.gov/38923164Test

الإتاحة: https://doi.org/10.1002/alz.13901Test
https://pubmed.ncbi.nlm.nih.gov/38923164Test