المؤلفون: Wandong Hong, Emanuele Pausini, Giovanni Posabella, Claudio Gallo, Dario de Biase, Enrico Giampieri, Sirio Fiorino, Maddalena Zippi, Tommaso Guarniero, Lari Federico, Marco Zancanaro, Antonio Tropeano, Donato Antonacci, Ivan Corazza, Carlotta Pausini

المساهمون: Gallo, Claudio G., Fiorino, Sirio, Posabella, Giovanni, Antonacci, Donato, Tropeano, Antonio, Pausini, Emanuele, Pausini, Carlotta, Guarniero, Tommaso, Hong, Wandong, Giampieri, Enrico, Corazza, Ivan, Federico, Lari, de Biase, Dario, Zippi, Maddalena, Zancanaro, Marco

المصدر: Cytokine

مصطلحات موضوعية: Male, Rantes, regulated on activation, normal T cell expressed and secreted, Disease, Review Article, Biochemistry, Pathogenesis, sepsis, IL-17, Interleukin 17, CoV-2, Immunology and Allergy, MOF, Multiple organ failure, ncMonocytes, non-classical Monocytes, TGF-β, transforming growth factor β, Sex Characteristics, IL-1R, IL-1 Receptor, ARDS, Acute Respiratory Distress Syndrome, Hematology, CRP, C-reactive Protein, IL-1RA, Interleukin-1 Receptor Antagonist, gender differences, CoV-2 Covid-19 Sepsis Acute pancreatitis Aging, IL-6, Interleukin 6, Acute pancreatitis, Female, cMonocytes, classical Monocytes, IL-1β, Interleukin 1β, medicine.symptom, Covid-19, medicine.medical_specialty, acute pancreatitis, Immunology, Anosmia, intMonocytes, Intermediate Monocytes, CCL5, Chemokine (C-C motif) ligand 5, BALF, Bronchoalveolar Lavage Fluid, Sepsis, IL-8, Interleukin 8, Internal medicine, ALI, Acute Lung Injury, medicine, Humans, Molecular Biology, Pathological, ESR, erythrocyte sedimentation rate, LDH, Lactate Dehydrogenase, IL-10, Interleukin 10, SARS-CoV-2, business.industry, aging, SIRS, Systemic Inflammatory Response Syndrome, Ageusia, medicine.disease, TNFα, Tumor Necrosis Factor α, CARS, compensatory anti-inflammatory response syndrome, Dysgeusia, Pancreatitis, TLRs, Toll-Like Receptors, MCP-1, Monocyte Chemoattractant Protein-1, business

وصف الملف: ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc5bc622876b2811e9fa103e60fd5c37Test
http://hdl.handle.net/11585/830660Test

المؤلفون: K B Megha, X. Joseph, V. Akhil, P.V. Mohanan

المصدر: Phytomedicine

مصطلحات موضوعية: EPO, Erythropoietin, FCAS, Familial cold-associated syndrome, MERS, Middle East Respiratory Syndrome, MAPK, Mitogen-activated protein kinase, CINCA, Chronic infantile neurologic cutaneous articular, Pharmaceutical Science, X-SCID, X-linked severe combined immunodeficiency, NOMID, Neonatal onset multisystem inflammatory disease, PD, Parkinson's disease, CAMs, Cell adhesion molecules, MODS, Multiple organ dysfunction syndromes, HBV, Hepatitis-B virus, SARS, Severe Acute Respiratory Syndrome, Interferon, Drug Discovery, TPO, Thrombopoietin, LIF, Leukemia inhibitory factor, NF-κB, Nuclear factor kappa-B, TNF-α, Tumor necrosis factor-α, CRS, Cytokine release syndrome, NK, Natural Killer cells, MKD, Mevalonate kinase deficiencies, TLR, Toll like receptors, CLL, Chronic lymphocytic leukemia, GM-CSF, Granulocyte/macrophage colony-stimulating factor, RA, Rheumatic arthritis, Interleukin, inflammatory response, interferon, APC, Antigen-presenting cells, TGF, Transforming growth factor, WBC, White blood cells, IFNγ, Interferon-γ, Cytokine release syndrome, GI, Gastro-Intestinal, ICAM, Intracellular adhesion molecule, CRP, C-reactive protein, Cytokines, Molecular Medicine, HIDS, Hyper immunoglobulin D and periodic fever syndrome, SARS-CoV-2, Severe acute respiratory syndrome corona virus 2, AD, Alzheimer's disease, IFNγR, IFN-γ receptors, medicine.symptom, JAK, Janus kinase, TNFR, TNF receptor, Cytokine Release Syndrome, TRAPS, Tumor necrosis factor receptor-associated periodic syndrome, IL-6R, IL-6 receptor, medicine.drug, DMARD, Disease modifying antirheumatic drug, Inflammation, COVID-19, Corona Virus Disease 2019, Article, Immune system, IBD, Inflammatory bowel diseases, ARDS, Acute respiratory distress syndrome, medicine, Humans, CTL, Cytotoxic T-cells, IL-6, Interleukin-6, HCV, Hepatitis-C virus, Pandemics, IL-1R, IL-1 receptor, MHC, Major histocompatibility complex, Pharmacology, OSM, Oncostatin M, STAT, Signal transducer and activator of transcription, SARS-CoV-2, business.industry, Mechanism (biology), COVID-19, FCU, Familial cold urticaria, IL-1β, Interleukin-1β, AHR, Airway hyper-responsiveness, ACE2, Angiotensin converting enzyme 2, CAPS, Cryopyrin-associated periodic syndromes, medicine.disease, interleukins, DIRA, Disorder associated with IL-1Ra, Complementary and alternative medicine, Immunology, CNTF, Ciliary neurotrophic factor, FMF, Familial Mediterranean fever, business, Cytokine storm, MWS, Muckle Wells syndrome, MA, Mevalonic aciduria, Function (biology)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578cd992aeb443a4e220c2762f77e9a4Test
https://doi.org/10.1016/j.phymed.2021.153712Test

المؤلفون: Emmerich, Christoph H., Bakshi, Siddharth, Kelsall, Ian R., Ortiz-Guerrero, Juanma, Shpiro, Natalia, Cohen, Philip

المصدر: Biochemical and Biophysical Research Communications

مصطلحات موضوعية: IL-1, interleukin-1, TAK1, TGFβ-activated kinase 1, TNF, λ-PPase, bacteriophage λ protein phosphatase, Biochemistry, M1-Ub, Met1-linked ubiquitin, NOD, Nucleotide Oligomerisation Domain, Monocytes, Mice, Methionine, K63-Ub, Lys63-linked ubiquitin, BMDM, bone marrow-derived macrophages, TLR3, IKK, IκB kinase, Cells, Cultured, Innate immunity, HRP, horseradish peroxidase, M-CSF, Macrophage Colony Stimulating Factor, Ub, Ubiquitin, TRADD, TNF-receptor associated death domain protein, JNK, c-Jun N-terminal kinase, TLR, Toll-Like Receptor, TRIF, TIR-domain-containing adapter-inducing interferon-β, Protein Binding, Signal Transduction, TRAF, TNF-Receptor-Associated Factor, NOD1, TNFα, Tumour Necrosis Factor α, Biophysics, Article, IRAK, IL-1R-Associated Kinase, cIAP, cellular Inhibitor of Apoptosis, DUB, deubiquitylase, GST, glutathione-S-transferase, LUBAC, Animals, Humans, Immunologic Factors, MyD88, Myeloid Differentiation primary response gene 88, RIP, Receptor-Interacting Protein, Molecular Biology, IL-1R, IL-1 receptor, AMSH-LP, AMSH-like protein, TAB, TAK1-binding protein, Ubiquitin, USP, Ub-specific protease, Lysine, PNGase F, Protein Asparaginyl Glycosidase F, Ubiquitination, Cell Biology, LUBAC, Linear UBiquitin Assembly Complex, Immunity, Innate, PRRs, Pathogen Recognition Receptors, TNFR1, TNFα Receptor 1, dsRNA, double-stranded RNA, NEMO, NF-κB Essential Modifier

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2e3cf84b76d359cbd3a99a232d37b0c7Test

المؤلفون: Janet E. Brown, Robert E. Coleman, Stella D'Oronzo

المصدر: Journal of Bone Oncology, Vol 9, Iss, Pp 1-9 (2017)
Journal of Bone Oncology

مصطلحات موضوعية: 0301 basic medicine, Oncology, Pathology, RANK, receptor activator of nuclear factor kB, lcsh:Diseases of the musculoskeletal system, IGF, insulin-like growth factor, ER, estrogen receptor, ZNF217, zinc-finger protein 217, NTX and CTX, N- and C- telopeptides of type 1 collagen, BMDC, bone marrow derived cells, EMT, epithelial to mesenchymal transition, Review Article, TNF, tumour necrosis factor, P1NP and P1CP, N and C terminal pro-peptides of type 1 collagen, PDGF, platelet-derived growth factor, miRNA, micro RNA, Bone remodeling, Metastasis, Prostate cancer, Breast cancer, 0302 clinical medicine, BTM, bone turnover markers, BSP, bone sialoprotein, BTA, bone-targeting agents, Prostate, PTH, parathyroid hormone, M-CSF, macrophage colony stimulating factor, CCL2, chemokine C-C ligand 2, Bone metastasis, PlGF, placental growth factor, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, SREs, skeletal related events, VEGF, vascular endothelial growth factor, DTC, disseminated tumour cells, PTH-rP, PTH related protein, medicine.anatomical_structure, NSCLC, non-small cell LC, 030220 oncology & carcinogenesis, shRNA, short hairpin RNA, sBALP, serum BALP, Lung cancer, Bone turnover markers, PDGFRα, PDGF receptor α, medicine.medical_specialty, BALP, bone specific alkaline phosphatase, MAF, v-maf avian musculo-aponeurotic fibrosarcoma oncogene homolog, TRACP-5b, tartrate-resistant acid phosphatase type 5b, BC, breast cancer, GIPC1, PDZ domain–containing protein member 1, PC, prostate cancer, LC, lung cancer, lcsh:RC254-282, BM, bone metastases, 03 medical and health sciences, TGF-β, transforming growth factor-β, CTC, circulating tumour cells, Internal medicine, SDF-1, stromal cell-derived factor 1, medicine, β-CTX, CTX β isomer, uNTX, urinary NTX, IL-1R, IL-1 receptor, CAPG, macrophage-capping protein, 1CTP, cross-linked carboxy-terminal telopeptide of type 1 collagen, PYD, pyridinoline, business.industry, HR, hormone receptor, CaSR, calcium sensing receptor, medicine.disease, IL, interleukin, FGF, fibroblast growth factor, TRAF3, TNF receptor associated factor 3, BMPs, bone morphogenetic proteins, DPD, deoxypyridinoline, Her2, human epidermal growth factor receptor 2, PSA, prostate specific antigen, 030104 developmental biology, OPG, osteoprotegerin, RANK-L, RANK-ligand, CXCR, C–X–C motif chemokine receptor, CXCL, C–X–C motif chemokine ligand, lcsh:RC925-935, business, Biomarkers, Homing (hematopoietic)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::252a04c31673cc391f0309675ad5099eTest
https://eprints.whiterose.ac.uk/122151/1/1-s2.0-S2212137417300775-main.pdfTest

المؤلفون: Axel Knebel, Lorna Plater, Christoph H. Emmerich, Sam Strickson, Natalia Shpiro, Philip Cohen, David G. Campbell, Maria Stella Ritorto

المصدر: Biochemical Journal

مصطلحات موضوعية: Lipopolysaccharides, Ubiquitin-conjugating enzyme, Biochemistry, DMEM, Dulbecco’s modified Eagle’s medium, Mice, linear ubiquitin assembly complex (LUBAC), K63-pUb, Lys63-linked polyubiquitin, NF-KappaB Inhibitor alpha, Ubiquitin, MS/MS, tandem MS, nuclear factor κB (NF-κB), pUb, polyubiquitin, TRAF, tumour-necrosis-factor-receptor-associated factor, Sulfones, RBR, RING-between-RING, TAB, TAK1-binding protein, IKK, IκB kinase, IκB, inhibitor of NF-κB, GFP, green fluorescent protein, HOIP, haem-oxidized IRP2 ligase-1-interacting protein, NEMO, NF-κB essential modifier, K48-pUb, Lys48-linked polyubiquitin, biology, LUBAC, linear ubiquitin assembly complex, Kinase, NEDD8, neural-precursor-cell-expressed developmentally down-regulated 8, Ubiquitin ligase, HRMS, high-resolution mass spectra, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, TBK1, tumour-necrosis-factor-receptor-associated factor-associated NF-κB activator-binding kinase 1, JNK, c-Jun N-terminal kinase, LPS, lipopolysaccharide, Phosphorylation, I-kappa B Proteins, ubiquitin conjugating 13 (Ubc13), NF-κB, nuclear factor κB, DLBCL, diffuse large B-cell lymphoma, PAMP, pathogen-associated molecular pattern, Signal Transduction, Research Article, Proteasome Endopeptidase Complex, Molecular Sequence Data, lymphoma, MALDI–TOF, matrix-assisted laser-desorption ionization–time-of-flight, ERK, extracellular-signal-regulated kinase, HEK, human embryonic kidney, Ubc, ubiquitin conjugating, Cell Line, Tumor, Nitriles, MyD88, myeloid differentiation factor 88, Animals, Humans, Amino Acid Sequence, Molecular Biology, HIF1α, hypoxia-inducible factor 1α, IL-1R, IL-1 receptor, HTLV-1, human T-cell lymphotropic virus 1, Macrophages, HEK 293 cells, Ubiquitination, NF-kappa B p50 Subunit, Receptors, Interleukin-1, myeloid differentiation factor 88 (MyD88), TAK1, transforming growth factor β-activated kinase 1, Cell Biology, Hypoxia-Inducible Factor 1, alpha Subunit, Molecular biology, IL, interleukin, UBE, ubiquitin-activating enzyme, IκBα, proteasome, Gene Expression Regulation, Proteasome, IRAK, IL-receptor-associated kinase, Myeloid Differentiation Factor 88, Ubiquitin-Conjugating Enzymes, biology.protein, MAPK, mitogen-activated protein kinase, Interleukin-1, DAPI, 4′,6-diamidino-2-phenylindole

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af6008194e741619655a2e05fd75147Test
https://doi.org/10.1042/bj20121651Test

المؤلفون: Emmerich, Christoph H., Cohen, Philip

المصدر: Biochemical and Biophysical Research Communications

مصطلحات موضوعية: TUBEs, tandem-repeated ubiquitin-binding entities, TA, tris-acetate, Mini Review, TG, tris-glycine, Immunoblotting, Biophysics, UBD, ubiquitin-binding domain, TNF, tumour necrosis factor, Biochemistry, GST, glutathione S-transferase, HEK, human embryonic kidney, DUB, deubiquitylase, pUb, polyubiquitin, Animals, Humans, Immunoprecipitation, RIP, receptor interacting protein, POI, protein of interest, SDS, sodium dodecyl sulphate, Deubiquitylase, Molecular Biology, UBAN, ubiquitin binding in ABIN and NEMO domain, IL-1R, IL-1 receptor, NEMO, NF-κB essential modulator, UBA, ubiquitin-associated, Ubiquitin, Ubiquitination, Ubiquitin chain topology, IRAK, interleukin receptor associated kinase, PPase, phage λ-phosphatase, IP, immunoprecipitation, MES, 2-(N-morpholino) ethane sulfonic acid, Cell Biology, LUBAC, Linear UBiquitin Assembly Complex, Ubiquitinated Proteins, PVDF, polyvinyl difluoride, TNF-R, TNF receptor, Up-Regulation, Ubiquitin-binding-domain, DMP, dimethyl pimelidinate, IMAC, immobilised metal ion affinity chromatography, NEM, N-ethylmaleimide, MOPS, 3-(N-morpholino) propane sulfonic acid, Electrophoresis, Polyacrylamide Gel, Ubiquitin-Specific Proteases, IAA, iodoacetamide, NC, nitrocellulose, NZF, Npl4 zinc finger, UIM, ubiquitin-interacting motif

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::54e4eff6d3fa9c1c0c3d5b17681e3be7Test