المؤلفون: Phan T., Zitzmann C., Chew K.W, Smith D.M, Daar E.S, Wohl D.A, Eron J.J, Currier J.S, Hughes M.D, Choudhary M.C, Deo R, Li J.Z, Ribeiro R.M, Ke R., Perelson A.S.

المصدر: PLoS Pathogens, 20(4-Apr)

مصطلحات موضوعية: life cycle, bamlanivimab, Article, SARS-CoV-2 antibody, immune response, IC90, Severe acute respiratory syndrome coronavirus 2, human, innate immunity, genotype, human experiment, disease severity, virus load, cohort analysis, virus resistance, symptom, adaptive immunity, coronavirus disease 2019, frequency, concentration (parameter), monoclonal antibody

العلاقة: https://doi.org/10.17615/zyb7-kc60Test; https://cdr.lib.unc.edu/downloads/j098zn75d?file=thumbnailTest; https://cdr.lib.unc.edu/downloads/j098zn75dTest

الإتاحة: https://doi.org/10.17615/zyb7-kc60Test
https://cdr.lib.unc.edu/downloads/j098zn75d?file=thumbnailTest
https://cdr.lib.unc.edu/downloads/j098zn75dTest

المؤلفون: Giordanetto, Fabrizio, Knerr, Laurent, Nordberg, Peter A., Pettersen, Daniel, Selmi, Nidhal, Beisel, Hans Georg, de la Motte, Hanna, Månsson, Åsa, Dahlström, Mikael, Broddefalk, Johan, Saarinen, Gabrielle, Klingegård, Fredrik, Hurt-Camejo, Eva, Rosengren, Birgitta, Wikström, Johannes, Wågberg, Maria, Brengdahl, Johan, Rohman, Mattias, Sandmark, Jenny, Åkerud, Tomas, Roth, Robert G., Jansen, Frank, Ahlqvist, Marie

المصدر: ACS Medicinal Chemistry Letters. 9(7):600-605

مصطلحات موضوعية: atherosclerosis, carotid ligation, coronary artery disease, inhibitor, Secreted phospholipase A2 type X, sPLA2-X, 2 [2 [carbamoyl 6 (trifluoromethoxy) 1h indol 1 yl]pyridine 2 yl]propanoic Acid, propionic acid derivative, unclassified drug, animal experiment, animal model, Article, carotid artery ligation, controlled study, drug absorption, drug bioavailability, drug clearance, drug design, drug potency, drug selectivity, IC50, IC90, in vitro study, in vivo study, lipophilicity, male, mouse, nonhuman, plasma protein binding, priority journal

وصف الملف: print

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:ri:diva-37293Test

المؤلفون: Qamar Shubbar, Raafat El-Awady, Soraya Mouffak, Ekram M. Saleh

المصدر: Biomedicine & Pharmacotherapy
Biomedicine & Pharmacotherapy, Vol 143, Iss, Pp 112107-(2021)

مصطلحات موضوعية: MERS, Middle East Respiratory Syndrome, IRE1, Inositol-requiring enzyme, Fluvoxamine, 1KD, Equilibrium dissociation constant (binding affinity), Dexamethasone, chemistry.chemical_compound, NIH, National Institutes of Health, SARS, Severe Acute Respiratory Syndrome, sdNbs, Single domain nanobodies, CoV, Coronavirus, SSRI, IC90, Concentration that inhibits 90% of the virions, EC50, half maximum neutralization concentration, Melatonin, ADE, Antibody dependant enhancement of the disease, ARDS, Acute Respiratory Distress Syndrome, General Medicine, Tocilizumab, Famotidine, ICU, Intensive care unit, Treatment Outcome, Drug development, IL-6, Interleukin 6, Nanobodies, SARS-CoV-2, Severe acute respiratory syndrome corona virus 2, EUA, Emergency Use Authorization, medicine.drug, SPR, Surface plasmon resonance, TMPRSS2, Transmembrane serine protease 2, medicine.medical_specialty, Serotonin, COVID-19 Vaccines, TNF-alpha, Tumor Necrosis Factor alpha, medicine.drug_class, Medication Therapy Management, CVT, Cerebral Venous Thrombosis, OTC, Over the Counter medication, RBD, Receptor binding domain, Remdesivir, RM1-950, Antiviral Agents, COVID-19, Coronavirus disease-2019, Article, WHO, World Health Organization, Viral life cycle, Drug Development, Fluoxetine, Medication therapy management, medicine, Humans, RdRp, RNA-dependent RNA polymerase, Intensive care medicine, NOS, Reactive nitrogen species, S1R, Sigma 1 receptor, Pharmacology, CDC, Centers for Disease Control and prevention, Ivermectin, business.industry, SARS-CoV-2, Nbs, Nanobodies, COVID-19, LPS, Lipopolysaccharides, FDA, Food and Drug Administration, COVID-19 Drug Treatment, Clinical trial, chemistry, IC50, Half maximal inhibitory concentration, Monoclonal antibodies, Therapeutics. Pharmacology, Antiviral drug, PCR, Polymerase chain reaction, business, NEJM, The New England Journal of Medicine, IMP, Importin, ROS, Reactive oxygen species

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a11381377b7725d056283c8ecacd49Test
http://europepmc.org/articles/PMC8390390Test

المؤلفون: Buse Cevatemre, Didem Karakas, Ferda Ari, Ceyda Icsel, Engin Ulukaya, Nazlihan Aztopal, Maria Grazia Daidone

المساهمون: Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Biyoloji Bölümü., Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Kimya Bölümü., Aztopal, Nazlihan, Karakaş, Didem, Cevatemre, Buse, Arı, Ferda, İçsel, Ceyda, AAV-4886-2020, L-6687-2018, L-6682-2018, AHD-2050-2022, AAG-7012-2021, AAI-3342-2021, İstinye Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Ulukaya, Engin

المصدر: Bioorganicmedicinal chemistry. 25(1)

مصطلحات موضوعية: Palladium(ii), Cell viability, Cell self-renewal, Organoplatinum Compounds, Biochemistry & molecular biology, Caspase inhibitor, Cell, Apoptosis, IC50, Octamer transcription factor 4, Transcription factor Sox2, Gene, Biochemistry, Induction, Carboplatin, Breast cancer, 0302 clinical medicine, ATP viability assay, Drug Discovery, Pathology, Cytotoxic T cell, Enzyme activity, Cell Self Renewal, Chemistry, organic, Breast cancer stem cells, 2-(hydroxymethyl)pyridine, Cell biology, Antineoplastic agent, 030220 oncology & carcinogenesis, Antineoplastic Activity, Prodrugs, Transplatin, MCF-7 Cells, Neoplastic Stem Cells, Oligopeptides, Drug mechanism, Human, Cytotoxic efficacy, Antineoplastic Agents, Article, 03 medical and health sciences, Necrosis, Cancer stem cell, Dose response, Humans, Anti-muc1, Molecular Biology, Pharmacology & pharmacy, HRK gene, Drug effect, 030104 developmental biology, SOX2 protein, human, MLKL gene, Cancer cell, Protein expression, Gene expression, Cisplatin, Mammosphere, Octamer Transcription Factor-3, 0301 basic medicine, Indoles, Resistance, Clinical Biochemistry, Assay, Pharmaceutical Science, POU5F1 protein, human, MCF-7 cell line, Breast cell, IC90, Western blotting, TNFRSF10A gene, Cancer inhibition, Flow cytometry, Caspase 7, Membrane Potential, Mitochondrial, Platinum complex, Caspase 3, Chemistry, Imidazoles, Anti-growth effect, Caspase Inhibitors, medicine.anatomical_structure, transcription factor Sox, Necroptosis, Oligopeptide, Molecular Medicine, Female, Mitochondrial membrane potential, Chemistry, medicinal, Cell death, Tumor heterogeneity, Drug cytotoxicity, Programmed cell death, Dinuclear platinum(II) complex, Breast tumor, Breast Neoplasms, antineoplastic activity, medicine, Viability assay, Platinum, Imidazole derivative, SOXB1 Transcription Factors, Organic Chemistry, Dichloridobis(2-(2-hydroxyethyl)pyridine)platinum(II), Metabolism, Indole derivative, Structural-characterization, Benzyloxycarbonyl-valyl-alanyl-aspartic acid, Necrostatin-1, Controlled study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488f6f72a6ff6b48fec3a71887ede952Test
https://pubmed.ncbi.nlm.nih.gov/27839660Test

المؤلفون: Maurice, HB, Tuarira, E, Mwambete, K

المصدر: African Journal of Biotechnology; Vol 8, No 13 (2009)

مصطلحات موضوعية: Docking, high throughput screening, Mycobacterium tuberculosis, ligands, 14∝-lanosterol demethylase and IC90

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=78975075580c::1daf93df680013e3a789fd90722292c4Test
https://www.ajol.info/index.php/ajb/article/view/60991Test

المؤلفون: Siedlecka-Kroplewska, Kamila, Jozwik, Agnieszka, Kaszubowska, Lucyna, Kowalczyk, Anna, Boguslawski, Wojciech

المساهمون: Polish Ministry of Science and Higher Education

المصدر: Folia Histochemica et Cytobiologica; Vol 50, No 4 (2012); 574-580

مصطلحات موضوعية: cell biology, pterostilbene, polyphenols, IC90, cell cycle, apoptosis, caspase-3, mitochondrial potential, ROS, MOLT4 leukemia cells

وصف الملف: application/pdf

العلاقة: https://journals.viamedica.pl/folia_histochemica_cytobiologica/article/view/FHC.2012.0080Test

الإتاحة: https://doi.org/10.5603/FHC.2012.0080Test
https://journals.viamedica.pl/folia_histochemica_cytobiologica/article/view/FHC.2012.0080Test