المؤلفون: Nsiah, Nana Yaa, Morgan, Autumn B., Donkor, Nina, Inman, Denise M.

المصدر: Scientific Reports

مصطلحات موضوعية: Glaucoma / pathology, Ocular Hypertension / pathology

وصف الملف: application/pdf

العلاقة: https://doi.org/10.1038/s41598-023-47942-8Test; Nsiah, N. Y., Morgan, A. B., Donkor, N., & Inman, D. M. (2023). Long-term HIF-1α stabilization reduces respiration, promotes mitophagy, and results in retinal cell death. Scientific reports, 13(1), 20541. https://doi.org/10.1038/s41598-023-47942-8Test; https://hdl.handle.net/20.500.12503/32445Test; 13

الإتاحة: https://doi.org/20.500.12503/32445Test
https://doi.org/10.1038/s41598-023-47942-8Test
https://hdl.handle.net/20.500.12503/32445Test

المؤلفون: Morton, Lorena, Ulbrich, Philipp, Garza, Alejandra P, Jandke, Solveig, Mattern, Hendrik, Gonzalez, Marilyn, Dityatev, Alexander, Yilmazer-Hanke, Deniz, Schreiber, Stefanie, Dunay, Ildiko R

المصدر: Acta Neuropathologica Communications 11(1), 204 (2023). doi:10.1186/s40478-023-01672-0

مصطلحات موضوعية: info:eu-repo/classification/ddc/610, Rats, Humans, Mice, Animals, Microglia: metabolism, Hypertension: complications, Hypertension: pathology, Inbred SHR, Cerebral Small Vessel Diseases: pathology, Phenotype, Cerebral small vessel disease (cSVD), Chronic arterial hypertension, Microglia, Spontaneously hypertensive stroke-prone rat (SHRSP)

جغرافية الموضوع: DE

العلاقة: info:eu-repo/semantics/altIdentifier/issn/2051-5960; info:eu-repo/semantics/altIdentifier/pmid/pmid:38115109; https://pub.dzne.de/record/266740Test; https://pub.dzne.de/search?p=id:%22DZNE-2024-00003%22Test

الإتاحة: https://doi.org/10.1186/s40478-023-01672-0Test
https://pub.dzne.de/record/266740Test
https://pub.dzne.de/search?p=id:%22DZNE-2024-00003%22Test

المؤلفون: Khoury, Spiro, Beauvais, Antoine, Colas, Jenny, Saint-Martin Willer, Anaïs, Perros, Frédéric, Humbert, Marc, Vandebrouck, Clarisse, Montani, David, Ferreira, Thierry, Antigny, Fabrice

المساهمون: Physiopathologie et régulation des transports ioniques (PRéTI Poitiers ), Université de Poitiers = University of Poitiers (UP), Hypertension pulmonaire : physiopathologie et innovation thérapeutique (HPPIT), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Centre de Référence de l’Hypertension Pulmonaire Sévère CHU Le Kremlin Bicêtre, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Bicêtre AP-HP, Le Kremlin-Bicêtre, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Faculté de Médecine Paris-Saclay, Hôpital Bicêtre AP-HP, Le Kremlin-Bicêtre, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Saclay, ANR-18-CE14-0023,KAPAH,KCNK3 une nouvelle cible thérapeutique dans l'hypertension artérielle pulmonaire(2018)

المصدر: ISSN: 2218-273X ; Biomolecules ; https://hal.science/hal-04520239Test ; Biomolecules, 2022, 12 (12), pp.1878. ⟨10.3390/biom12121878⟩.

مصطلحات موضوعية: PVOD, lysophosphatidylcholine, phospholipids, MESH: Humans, MESH: Lipidomics, MESH: Lung / pathology, MESH: Protein Serine-Threonine Kinases / genetics, MESH: Pulmonary Arterial Hypertension* / pathology, MESH: Pulmonary Veins, MESH: Pulmonary Veno-Occlusive Disease* / genetics, MESH: Pulmonary Veno-Occlusive Disease* / pathology, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36551306; hal-04520239; https://hal.science/hal-04520239Test; https://hal.science/hal-04520239/documentTest; https://hal.science/hal-04520239/file/biomolecules-12-01878-v2.pdfTest; PUBMED: 36551306; PUBMEDCENTRAL: PMC9775349

الإتاحة: https://doi.org/10.3390/biom12121878Test
https://hal.science/hal-04520239Test
https://hal.science/hal-04520239/documentTest
https://hal.science/hal-04520239/file/biomolecules-12-01878-v2.pdfTest

المؤلفون: Hernandez, Humberto, Medina-Ortiz, Wanda E., Luan, Tomi, Clark, Abbot F., McDowell, Colleen M.

المصدر: Investigative Ophthalmology & Visual Science

مصطلحات موضوعية: Animals, Aqueous Humor / metabolism, Blotting, Western, Cells, Cultured, Gene Expression Regulation, Humans, Immunohistochemistry, Intraocular Pressure, Mice, Inbred AKR, Inbred C3H, Ocular Hypertension / genetics, Ocular Hypertension / metabolism, Ocular Hypertension / pathology, RNA / genetics, Real-Time Polymerase Chain Reaction, Signal Transduction, Toll-Like Receptor 4 / biosynthesis, Toll-Like Receptor 4 / genetics, Trabecular Meshwork / metabolism, Trabecular Meshwork / pathology, Transforming Growth Factor beta2 / biosynthesis, Transforming Growth Factor beta2 / genetics

وصف الملف: application/pdf

العلاقة: https://doi.org/10.1167/iovs.16-21331Test; Hernandez, H., Medina-Ortiz, W. E., Luan, T., Clark, A. F., & McDowell, C. M. (2017). Crosstalk Between Transforming Growth Factor Beta-2 and Toll-Like Receptor 4 in the Trabecular Meshwork. Investigative ophthalmology & visual science, 58(3), 1811-1823. https://doi.org/10.1167/iovs.16-21331Test; https://hdl.handle.net/20.500.12503/31725Test; 58

الإتاحة: https://doi.org/20.500.12503/31725Test
https://doi.org/10.1167/iovs.16-21331Test
https://hdl.handle.net/20.500.12503/31725Test

المؤلفون: Patel, Gaurang C., Liu, Yang, Millar, J. Cameron, Clark, Abbot F.

المصدر: Scientific Reports

مصطلحات موضوعية: Animals, Collagen Type I / metabolism, Cytoskeletal Proteins / metabolism, Dexamethasone / pharmacology, Eye Proteins / metabolism, Female, Fibronectins / metabolism, Genetic Vectors / metabolism, Glucocorticoids / pharmacology, Glycoproteins / metabolism, Intraocular Pressure / drug effects, Male, Mice, Inbred C57BL, Ocular Hypertension / etiology, Ocular Hypertension / metabolism, Ocular Hypertension / pathology, Receptors, Glucocorticoid / genetics, Glucocorticoid / metabolism, Trabecular Meshwork / cytology, Trabecular Meshwork / drug effects, Trabecular Meshwork / metabolism

وصف الملف: application/pdf

العلاقة: https://doi.org/10.1038/s41598-018-19262-9Test; Patel, G. C., Liu, Y., Millar, J. C., & Clark, A. F. (2018). Glucocorticoid receptor GRβ regulates glucocorticoid-induced ocular hypertension in mice. Scientific reports, 8(1), 862. https://doi.org/10.1038/s41598-018-19262-9Test; https://hdl.handle.net/20.500.12503/31726Test

الإتاحة: https://doi.org/20.500.12503/31726Test
https://doi.org/10.1038/s41598-018-19262-9Test
https://hdl.handle.net/20.500.12503/31726Test

المؤلفون: Kasetti, Ramesh B., Patel, Pinkal D., Maddineni, Prabhavathi, Patil, Shruti, Kiehlbauch, Charles, Millar, J. Cameron, Searby, Charles C., Raghunathan, Vijaykrishna, Sheffield, Val C., Zode, Gulab S.

المصدر: Nature Communications

مصطلحات موضوعية: Activating Transcription Factor 4 / antagonists & inhibitors, Activating Transcription Factor 4 /genetics, Activating Transcription Factor 4 /metabolism, Animals, Aqueous Humor / metabolism, Cell Death, Cells, Cultured, Endoplasmic Reticulum Stress / drug effects, Endoplasmic Reticulum Stress / genetics, Glaucoma, Open-Angle / drug therapy, Open-Angle / metabolism, Open-Angle / pathology, Humans, Mice, Ocular Hypertension / drug therapy, Ocular Hypertension / metabolism, Ocular Hypertension / pathology, Optic Nerve / metabolism, Optic Nerve / pathology, Protein Biosynthesis / drug effects, Protein Phosphatase 1 / genetics, Protein Phosphatase 1 / metabolism, Retinal Ganglion Cells / metabolism, Retinal Ganglion Cells / pathology, Signal Transduction, Trabecular Meshwork / drug effects, Trabecular Meshwork / metabolism, Trabecular Meshwork / pathology

وصف الملف: application/pdf

العلاقة: https://doi.org/10.1038/s41467-020-19352-1Test; Kasetti, R. B., Patel, P. D., Maddineni, P., Patil, S., Kiehlbauch, C., Millar, J. C., Searby, C. C., Raghunathan, V., Sheffield, V. C., & Zode, G. S. (2020). ATF4 leads to glaucoma by promoting protein synthesis and ER client protein load. Nature communications, 11(1), 5594. https://doi.org/10.1038/s41467-020-19352-1Test; https://hdl.handle.net/20.500.12503/31990Test; 11

الإتاحة: https://doi.org/20.500.12503/31990Test
https://doi.org/10.1038/s41467-020-19352-1Test
https://hdl.handle.net/20.500.12503/31990Test

المؤلفون: Wild, Johannes, Wenzel, Philip

المصدر: http://lobid.org/resources/99370678534106441Test#!, 99(3):315-326.

مصطلحات موضوعية: Antimicrobial Cationic Peptides/immunology [MeSH], Essential hypertension, Gastrointestinal Microbiome/immunology [MeSH], NLR Family, Pyrin Domain-Containing 3 Protein/physiology [MeSH], Hypertension/immunology [MeSH], Models, Animal [MeSH], Toll-Like Receptors/immunology [MeSH], Immune system, Sodium/metabolism [MeSH], Dysbiosis/immunology [MeSH], Immunity, Innate [MeSH], Water-Electrolyte Balance/physiology [MeSH], Arterial hypertension, Hypertension/chemically induced [MeSH], Skin/immunology [MeSH], Humans [MeSH], Inflammasomes/physiology [MeSH], Sodium Chloride, Dietary/toxicity [MeSH], Rats [MeSH], Hypertension/pathology [MeSH], Innate immune system, Myeloid Cells/immunology [MeSH], Animals [MeSH], Intestinal Mucosa/immunology [MeSH], Desoxycorticosterone Acetate/toxicity [MeSH], Complement Activation [MeSH]

العلاقة: https://repository.publisso.de/resource/frl:6448307Test; https://doi.org/10.1007/s00109-020-02019-1Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899956Test/

الإتاحة: https://doi.org/10.1007/s00109-020-02019-1Test
https://repository.publisso.de/resource/frl:6448307Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899956Test/

المساهمون: Si Hyung Lee, Kyung Sun Shim, Chan Yun Kim, Tae Kwann Park, Kim, Chan Yun

مصطلحات موضوعية: Adenylate Kinase / metabolism, Animals, Autophagy, Biomarkers / metabolism, Cell Survival, Chronic Disease, Disease Models, Animal, Intravitreal Injections, Male, Microtubule-Associated Proteins / metabolism, Ocular Hypertension / pathology, Phosphorylation, Rats, Sprague-Dawley, Retinal Ganglion Cells / drug effects, Retinal Ganglion Cells / pathology, Retinal Ganglion Cells / ultrastructure, Signal Transduction, Sirolimus / administration & dosage, Sirolimus / pharmacology, Sutures, TOR Serine-Threonine Kinases / metabolism, Time Factors

العلاقة: SCIENTIFIC REPORTS; J02646; OAK-2022-04225; https://ir.ymlib.yonsei.ac.kr/handle/22282913/190374Test; T202126048; SCIENTIFIC REPORTS, Vol.11(1) : 5767, 2021-03

الإتاحة: https://doi.org/10.1038/s41598-021-85181-xTest
https://ir.ymlib.yonsei.ac.kr/handle/22282913/190374Test

المؤلفون: Baron, Morgane, Maillet, Julie, Huyvaert, Marlène, Dechaume, Aurélie, Boutry, Raphael, Loiselle, Hélène, Durand, Emmanuelle, Toussaint, Bénédicte, Vaillant, Emmanuel, Philippe, Julien, Thomas, Jérémy, Ghulam, Amjad, Franc, Sylvia, Charpentier, Guillaume, Borys, Jean-Michel, Lévy-Marchal, Claire, Tauber, Maïthé, Scharfmann, Raphaël, Weill, Jacques, Aubert, Cécile, Kerr-Conte, Julie, Pattou, François, Roussel, Ronan, Balkau, Beverley, Marre, Michel, M., Boissel, Mathilde, Derhourhi, Mehdi, Gaget, Stefan, Canouil, Mickael, Froguel, Philippe, Bonnefond, Amélie

المساهمون: Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283 (EGENODIA (GI3M)), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Centre d'études et de recherches pour l'intensification du traitement du diabète (CERITD), Centre Hospitalier Sud Francilien, Association Fleurbaix Laventie Ville Santé (FLVS), Centre d'Investigation Clinique - Epidemiologie Clinique/essais Cliniques Hopital Robert Debre, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Service d'endocrinologie pédiatrique CHU Lille, Hôpital Jeanne de Flandre Lille -Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Fondation ILDYS (ILDYS), Recherche translationnelle sur le diabète - U 1190 (RTD), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), AP-HP - Hôpital Bichat - Claude Bernard Paris, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Diderot, Sorbonne Paris Cité, Paris, France, Université Paris Diderot - Paris 7 (UPD7), Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), AP-HP. Université Paris Saclay, Clinique Ambroise Paré Centres Médico-Chirurgicaux Ambroise Pré, Pierre Cherest, Hartmann, Imperial College London, This work was supported by grants from the French-speaking Society of Diabetes (Société Française du Diabète) to A.B., from the European Foundation for the Study of Diabetes/Lilly (to A.B.), from the French National Research Agency (ANR-10-LABX-46 (European Genomics Institute for Diabetes) and ANR-10-EQPX-07-01 (LIGAN-PM) to P.F.), from the European Research Council (ERC GEPIDIAB-294785 to P.F. and ERC Reg-Seq-715575 to A.B.), from FEDER (to P.F.) and from the ‘Région Nord Pas-de-Calais’ (to P.F.). A.B. was supported by Inserm., ANR-10-EQPX-0007,LIGAN PM,Plate forme Lilloise de séquençage du génome humain pour une médecine personnalisée(2010), European Project: 294785,EC:FP7:ERC,ERC-2011-ADG_20110310,GEPIDIAB(2012)

المصدر: ISSN: 1078-8956.

مصطلحات موضوعية: MESH: Adaptor Proteins, Signal Transducing / genetics, MESH: Energy Metabolism / genetics, MESH: Obesity / complications, MESH: Obesity / metabolism, MESH: Obesity / pathology, MESH: Receptor, Melanocortin, Type 4 / genetics, MESH: Genetic Predisposition to Disease, MESH: Humans, MESH: Hyperglycemia / pathology, MESH: Hyperphagia / complications, MESH: Hyperphagia / pathology, MESH: Hypertension / complications, MESH: Hypertension / pathology, MESH: Loss of Function Mutation / genetics, [SDV.GEN]Life Sciences [q-bio]/Genetics, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/31700171; info:eu-repo/grantAgreement/EC/FP7/294785/EU/Genetics and epigenetics of Type 2 Diabetes physiology/GEPIDIAB; inserm-02439220; https://inserm.hal.science/inserm-02439220Test; https://inserm.hal.science/inserm-02439220/documentTest; https://inserm.hal.science/inserm-02439220/file/nat-med-Baron-et-al.pdfTest; PUBMED: 31700171; PUBMEDCENTRAL: PMC6858878

الإتاحة: https://doi.org/10.1038/s41591-019-0622-0Test
https://inserm.hal.science/inserm-02439220Test
https://inserm.hal.science/inserm-02439220/documentTest
https://inserm.hal.science/inserm-02439220/file/nat-med-Baron-et-al.pdfTest

المؤلفون: Rossi, Stefano, Savi, Monia, Mazzola, Marta, Pinelli, Silvana, Alinovi, Rossella, Gennaccaro, Laura, Pagliaro, Alessandra, Meraviglia, Viviana, Galetti, Maricla, Lozano-Garcia, Omar, Rossini, Alessandra, Frati, Caterina, Falco, Angela, Quaini, Federico, Bocchi, Leonardo, Stilli, Donatella, Lucas, Stéphane, Goldoni, Matteo, Macchi, Emilio, Mutti, Antonio, Miragoli, Michele

المصدر: Rossi , S , Savi , M , Mazzola , M , Pinelli , S , Alinovi , R , Gennaccaro , L , Pagliaro , A , Meraviglia , V , Galetti , M , Lozano-Garcia , O , Rossini , A , Frati , C , Falco , A , Quaini , F , Bocchi , L , Stilli , D , Lucas , S , Goldoni , M , Macchi , E , Mutti , A & Miragoli , M 2019 , ' Subchronic exposure to titanium dioxide nanoparticles modifies cardiac structure and performance in spontaneously ....

مصطلحات موضوعية: Arrhythmias, Cardiac electrophysiology, Cardiac fibrosis, Nanotoxicology, Titanium dioxide nanoparticles, Rats, Inbred SHR, Hypertension/pathology, Ventricular Function, Left, Nanoparticles/toxicity, Telemetry, Dose-Response Relationship, Drug, Titanium/toxicity, Animals, Heart/drug effects, Blood Pressure/drug effects, Myocardium/pathology, Heart Rate/drug effects, Fibrosis, Electrocardiography

وصف الملف: application/pdf

العلاقة: https://researchportal.unamur.be/en/publications/1ffe691f-076f-483c-9561-3b36223dd155Test

الإتاحة: https://doi.org/10.1186/s12989-019-0311-7Test
https://researchportal.unamur.be/en/publications/1ffe691f-076f-483c-9561-3b36223dd155Test
https://pure.unamur.be/ws/files/41188878/s12989_019_0311_7.pdfTest
http://www.scopus.com/inward/record.url?scp=85068164872&partnerID=8YFLogxKTest