المؤلفون: Rovida, Costanza, Barton-Maclaren, Tara, Benfenati, Emilio, Caloni, Francesca, Chandrasekera, P. Charukeshi, Chesne, Christophe, Cronin, Mark T D, De Knecht, Joop, Dietrich, Daniel R, Escher, Sylvia E, Fitzpatrick, Suzanne, Flannery, Brenna, Herzler, Matthias, Hougaard Bennekou, Susanne, Hubesch, Bruno, Kamp, Hennicke, Kisitu, Jaffar, Kleinstreuer, Nicole, Kovarich, Simona, Leist, Marcel, Maertens, Alexandra, Nugent, Kerry, Pallocca, Giorgia, Pastor, Manuel, Patlewicz, Grace, Pavan, Manuela, Presgrave, Octavio, Smirnova, Lena, Schwarz, Michael, Yamada, Takashi, Hartung, Thomas

المساهمون: C. Rovida, T. Barton-Maclaren, E. Benfenati, F. Caloni, P.C. Chandrasekera, C. Chesne, M.T.D. Cronin, J. De Knecht, D.R. Dietrich, S.E. Escher, S. Fitzpatrick, B. Flannery, M. Herzler, S. Hougaard Bennekou, B. Hubesch, H. Kamp, J. Kisitu, N. Kleinstreuer, S. Kovarich, M. Leist, A. Maerten, K. Nugent, G. Pallocca, M. Pastor, G. Patlewicz, M. Pavan, O. Presgrave, L. Smirnova, M. Schwarz, T. Yamada, T. Hartung

مصطلحات موضوعية: new approach method, read-acro, regulatory toxicology, validation, Settore VET/07 - Farmacologia e Tossicologia Veterinaria

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32369604; info:eu-repo/semantics/altIdentifier/wos/WOS:000609370500005; volume:37; issue:4; firstpage:579; lastpage:606; numberofpages:28; journal:ALTERNATIVES TO ANIMAL EXPERIMENTATION; http://hdl.handle.net/2434/752498Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85090233549

الإتاحة: https://doi.org/10.14573/altex.1912181Test
http://hdl.handle.net/2434/752498Test

المؤلفون: Sauer, Ursula G., Barter, Robert A., Becker, Richard A., Benfenati, Emilio, Berggren, Elisabet, Hubesch, Bruno, Hollnagel, Heli M., Inawaka, Kunifumi, Keene, Athena M., Mayer, Philipp, Plotzke, Kathleen, Skoglund, Robert, Albert, Océane

المصدر: Sauer , U G , Barter , R A , Becker , R A , Benfenati , E , Berggren , E , Hubesch , B , Hollnagel , H M , Inawaka , K , Keene , A M , Mayer , P , Plotzke , K , Skoglund , R & Albert , O 2020 , ' 21 st Century Approaches for Evaluating Exposures, Biological Activity, and Risks of Complex Substances : Workshop highlights ' , Regulatory Toxicology and Pharmacology , vol. 111 , 104583 . https://doi.org/10.1016/j.yrtph.2020.104583Test

مصطلحات موضوعية: Adverse outcome pathway (AOP), Combined exposure, Exposure assessment, Integrated approach to testing and assessment (IATA), Mode-of-action (MoA), Multi-constituent substances, New approach methodologies (NAMs), UVCBs (substances of unknown or variable compositions, complex reaction products and biological substances)

وصف الملف: application/pdf

العلاقة: https://orbit.dtu.dk/en/publications/e7fb96f5-968d-4d29-a7af-200847cff86bTest

الإتاحة: https://doi.org/10.1016/j.yrtph.2020.104583Test
https://orbit.dtu.dk/en/publications/e7fb96f5-968d-4d29-a7af-200847cff86bTest
https://backend.orbit.dtu.dk/ws/files/205725608/1_s2.0_S027323002030009X_main_1_.pdfTest

المؤلفون: Desprez, Bertrand, Birk, Barbara, Blaauboer, Bas, Boobis, Alan, Carmichael, Paul, Cronin, Mark T.D., Curie, Richard, Daston, George, Hubesch, Bruno, Jennings, Paul, Klaric, Martina, Kroese, Dinant, Mahony, Catherine, Ouédraogo, Gladys, Piersma, Aldert, Richarz, Andrea Nicole, Schwarz, Michael, van Benthem, Jan, van de Water, Bob, Vinken, Mathieu

المصدر: Desprez , B , Birk , B , Blaauboer , B , Boobis , A , Carmichael , P , Cronin , M T D , Curie , R , Daston , G , Hubesch , B , Jennings , P , Klaric , M , Kroese , D , Mahony , C , Ouédraogo , G , Piersma , A , Richarz , A N , Schwarz , M , van Benthem , J , van de Water , B & Vinken , M 2019 , ' A mode-of-action ontology model for safety evaluation of chemicals : Outcome ....

مصطلحات موضوعية: Adverse outcome pathway, Mode-of-action, Ontology model, Repeated dose toxicity

وصف الملف: application/pdf

العلاقة: https://research.vu.nl/en/publications/01a954c0-c68f-4d42-8baf-6a2d630f7c10Test

الإتاحة: https://doi.org/10.1016/j.tiv.2019.04.005Test
https://research.vu.nl/en/publications/01a954c0-c68f-4d42-8baf-6a2d630f7c10Test
https://hdl.handle.net/1871.1/01a954c0-c68f-4d42-8baf-6a2d630f7c10Test
https://research.vu.nl/ws/files/122157950/A_modeofaction_ontology_model_for_safety_evaluation_of_chemicals.pdfTest
http://www.scopus.com/inward/record.url?scp=85064089407&partnerID=8YFLogxKTest
http://www.scopus.com/inward/citedby.url?scp=85064089407&partnerID=8YFLogxKTest

المؤلفون: Basketter, David, Azam, Philippe, Casati, Silvia, Corvaro, Marco, Ezendam, Janine, Griem, Peter, Hubesch, Bruno, Irizar, Amaia, Kern, Petra, Manou, Irene, Mehling, Annette, Rossi, Laura H.

المصدر: Regulatory Toxicology and Pharmacology ; volume 109, page 104477 ; ISSN 0273-2300

مصطلحات موضوعية: Toxicology, General Medicine

الإتاحة: https://doi.org/10.1016/j.yrtph.2019.104477Test
https://api.elsevier.com/content/article/PII:S0273230019302417?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0273230019302417?httpAccept=text/plainTest

المؤلفون: Laroche, Charles, Annys, Erwin, Bender, Hans, Botelho, Danielle, Botham, Phil, Brendler-Schwaab, Susanne, Clayton, Rick, Corvaro, Marco, Dal Negro, Gianni, Delannois, Frédérique, Dent, Matt, Desaintes, Christian, Desprez, Bertrand, Dhalluin, Stephane, Hartmann, Andreas, Hoffmann-Doerr, Simone, Hubesch, Bruno, Irizar, Amaia, Manou, Irene, Müller, Boris P., Nadzialek, Stephanie, Prieto, Pilar, Rasenberg, Mike, Roggeband, Rob, Rowan, Tim G., Schutte, Katrin, van de Water, Bob, Westmoreland, Carl, Whelan, Maurice, Wilschut, Annette, Zvonimir, Zvonar, Cronin, Mark T.D.

المساهمون: IMI, European Parliament, EU EU-ToxRisk Project, EU's Horizon 2020 research and innovation programme, European Crop Protection Association, Syngenta, Symrise AG

المصدر: Regulatory Toxicology and Pharmacology ; volume 108, page 104470 ; ISSN 0273-2300

مصطلحات موضوعية: Toxicology, General Medicine

الإتاحة: https://doi.org/10.1016/j.yrtph.2019.104470Test
https://api.elsevier.com/content/article/PII:S027323001930234X?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S027323001930234X?httpAccept=text/plainTest

المؤلفون: Laroche, Charles, Aggarwal, Manoj, Bender, Hans, Benndorf, Paul, Birk, Barbara, Crozier, Jonathan, Dal Negro, Gianni, De Gaetano, Federica, Desaintes, Christian, Gardner, Iain, Hubesch, Bruno, Irizar, Amaia, John, David, Kumar, Vikas, Lostia, Alfonso, Manou, Irene, Monshouwer, Mario, Müller, Boris P., Paini, Alicia, Reid, Kirsty, Rowan, Timothy, Sachana, Magdalini, Schutte, Katrin, Stirling, Catrina, Taalman, Rob, van Aerts, Leon, Weissenhorn, Renate, Sauer, Ursula G.

المصدر: Regulatory Toxicology and Pharmacology ; volume 99, page 5-21 ; ISSN 0273-2300

مصطلحات موضوعية: Toxicology, General Medicine

الإتاحة: https://doi.org/10.1016/j.yrtph.2018.08.006Test
https://api.elsevier.com/content/article/PII:S0273230018302186?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0273230018302186?httpAccept=text/plainTest

المؤلفون: Buesen, Roland, Chorley, Brian N, da Silva Lima, Beatriz, Daston, George P., Deferme, Lize, Ebbels, Timothy, Gant, Timothy W, Goetz, Amber, Greally, John, Gribaldo, Laura, Hackermüller, Jörg, Hubesch, Bruno, Jennen, Danyel G J, Johnson, Kamin, Kanno, Jun, Kauffmann, Hans-Martin, Laffont, Madeleine, McMullen, Patrick, Meehan, Richard, Pemberton, Mark, Perdichizzi, Stefania, Piersma, Aldert H, Sauer, Ursula G, Schmidt, Kerstin, Seitz, Hervé, Sumida, Kayo, Tollefsen, Knut Erik, Tong, Weida, Tralau, Tewes, van Ravenzwaay, Ben, Weber, Ralf J M, Worth, Andrew, Yauk, Carole, Poole, Alan

المساهمون: LS IRAS Tox RTX (Reprod.en ontw.toxic.), dIRAS RA-1

مصطلحات موضوعية: Regulatory toxicology, Transcriptomics, Metabolomics, Good laboratory practice (GLP), Weight-of-evidence (WoE), Adverse outcome pathway (AOP), Mode-of-action (MoA), Gene expression, Differentially expressed genes

وصف الملف: image/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/361049Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/361049Test

المؤلفون: Buesen, Roland, Chorley, Brian N., Lima, Beatriz da Silva, Daston, George, Deferme, Lize, Ebbels, Timothy, Gant, Timothy W., Goetz, Amber, Greally, John, Gribaldo, Laura, Hackermueller, Joerg, Hubesch, Bruno, Jennen, Danyel, Johnson, Kamin, Kanno, Jun, Kauffmann, Hans-Martin, Laffont, Madeleine, McMullen, Patrick, Meehan, Richard, Pemberton, Mark, Perdichizzi, Stefania, Piersma, Aldert H., Sauer, Ursula G., Schmidt, Kerstin, Seitz, Herve, Sumida, Kayo, Tollefsen, Knut E., Tong, Weida, Tralau, Tewes, van Ravenzwaay, Ben, Weber, Ralf J. M., Worth, Andrew, Yauk, Carole, Poole, Alan

المصدر: Buesen , R , Chorley , B N , Lima , B D S , Daston , G , Deferme , L , Ebbels , T , Gant , T W , Goetz , A , Greally , J , Gribaldo , L , Hackermueller , J , Hubesch , B , Jennen , D , Johnson , K , Kanno , J , Kauffmann , H-M , Laffont , M , McMullen , P , Meehan , R , Pemberton , M , Perdichizzi , S , Piersma , A H , Sauer , U G , Schmidt ....

مصطلحات موضوعية: Regulatory toxicology, Transcriptomics, Metabolomics, Good laboratory practice (GLP), Weight-of-evidence (WoE), Adverse outcome pathway (ADP), Mode-of-action (MoA), Gene expression, Differentially expressed genes, ADVERSE OUTCOME PATHWAYS, CONCEPTUAL-FRAMEWORK, KEY EVENTS, TOXICOGENOMICS, PERSPECTIVES, CONCORDANCE, CARCINOGENS, DEPARTURE, EXPOSURE

الإتاحة: https://doi.org/10.1016/j.yrtph.2017.09.002Test
https://cris.maastrichtuniversity.nl/en/publications/f2c16f03-c544-43b2-87aa-c56218d16778Test

المؤلفون: Maertens, Alexandra, Hubesch, Bruno, Rovida, Costanza

المصدر: ALTEX. 2016, 33(3), pp. 324-326. ISSN 1868-596X. eISSN 1868-8551. Available under: doi:10.14573/altex.1605301

مصطلحات موضوعية: ddc:570

وصف الملف: application/pdf

العلاقة: http://nbn-resolving.de/urn:nbn:de:bsz:352-0-417667Test; http://dx.doi.org/10.14573/altex.1605301Test; 493331042

الإتاحة: https://doi.org/10.14573/altex.1605301Test
http://nbn-resolving.de/urn:nbn:de:bsz:352-0-417667Test

المؤلفون: Aigner, Achim, Buesen, Roland, Gant, Tim, Gooderham, Nigel, Greim, Helmut, Hackermüller, Jörg, Hubesch, Bruno, Laffont, Madeleine, Marczylo, Emma, Meister, Gunter, Petrick, Jay S., Rasoulpour, Reza J., Sauer, Ursula G., Schmidt, Kerstin, Seitz, Hervé, Slack, Frank, Sukata, Tokuo, van der Vies, Saskia M., Verhaert, Jan, Witwer, Kenneth W., Poole, Alan

المساهمون: European Centre for Ecotoxicology and Toxicology of Chemicals, Long-range Research Initiative of the European Chemical Industry Council

المصدر: Regulatory Toxicology and Pharmacology ; volume 82, page 127-139 ; ISSN 0273-2300

مصطلحات موضوعية: Toxicology, General Medicine

الإتاحة: https://doi.org/10.1016/j.yrtph.2016.09.018Test
https://api.elsevier.com/content/article/PII:S0273230016302665?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0273230016302665?httpAccept=text/plainTest