نتائج البحث - "Host cell cytosol"

المساهمون: Biologie de Plasmodium et Vaccins - Malaria Parasite Biology and Vaccines, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Infection et Immunité paludéennes - Malaria Infection and Immunity, Plateforme BioImagerie Ultrastructurale – Ultrastructural BioImaging Platform (UTechS UBI), Institut Pasteur Paris (IP), Nanyang Technological University Singapour, Justus-Liebig-Universität Gießen = Justus Liebig University (JLU), Microbiologie structurale - Structural Microbiology (Microb. Struc. (UMR_3528 / U-Pasteur_5)), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Malaria Translational Research Unit (MTRU), Institut Pasteur du Cambodge, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut Pasteur Paris (IP), Perelman School of Medicine, University of Pennsylvania, Génétique du paludisme et résistance - Malaria Genetics and Resistance, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Dynamique des interactions Hôte pathogène, Université de Strasbourg (UNISTRA), Institut de Parasitologie et de Pathologie Tropicale (IPPTS), Mucoviscidose et bronchopathies chroniques : biopathologie et phénotype cliniques - Cystic Fibrosis and Bronchial Diseases, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Saint-Antoine AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Université Paris Cité (UPCité), This work was funded by the following grants: Fondation pour la Recherche Médicale grant (FDT202001010791) to M.P.W., Agence Nationale de la Recherche grant (ANR-17-CE15-0010) to C.E.C., Pasteur Innov grant from Institut Pasteur to C.E.C., Laboratoire d’Excellence (LabEx) “French Parasitology Alliance For Health Care” (ANR-11-LABX-0024-PARAFRAP) to C.E.C. and D.M., Laboratoire d’Excellence “Integrative Biology of Emerging Infectious Diseases” (grant no. ANR-10-LABX-62-IBEID) to P.F., NTU Presidential Postdoctoral Fellowship grant (NTU/PPF/2019) to J.M.D., Singaporean Ministry of Education grant (MOE-T2EP30120-0015) to J.M.D. and Z.B., and LOEWE Center DRUID (Projects B3) within the Hessian Excellence Program to I.B., We thank Gordon Langsley for fruitful discussions and critical inputs. We also thank the electron microscopy Ultrastructural BioImaging (UBI) platform, Institut Pasteur, Paris, for providing ready access to the electron microscopy facility. The authors are grateful to the Central Animal Facility of Institut Pasteur for providing support with animal importation, care, housing, and breeding. We thank the Image Analysis Hub (IAH), Institut Pasteur, Paris, for their help with image analysis. M.P.W. was part of the Pasteur - Paris University (PPU) International PhD Program and European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement no. 665807., ANR-17-CE15-0010,MolSigMal,Evènements moléculaires de la signalisation induite par l'invasion des globules rouges par les parasites paludéens(2017), ANR-11-LABX-0024,ParaFrap,Alliance française contre les maladies parasitaires(2011), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), European Project: 665807,H2020,H2020-MSCA-COFUND-2014,PASTEURDOC(2015)

المصدر: ISSN: 2211-1247.

مصطلحات موضوعية: CP: Metabolism, CP: Microbiology, PRDX6, Plasmodium falciparum, artemisinin, endocytosis, hemoglobin, host cell cytosol uptake, lipid peroxidation, malaria, molecular parasitology, oxidative stress, [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology