المؤلفون: Paulus, Felix, Holm, René, Stappaerts, Jef, Bauer-Brandl, Annette

المصدر: Paulus , F , Holm , R , Stappaerts , J & Bauer-Brandl , A 2024 , ' Absorption of cinnarizine from type II lipid-based formulations : Impact of lipid chain length, supersaturation, digestion, and precipitation inhibition ' , European Journal of Pharmaceutical Sciences , vol. 197 , 106765 . https://doi.org/10.1016/j.ejps.2024.106765Test

مصطلحات موضوعية: Drug solubility, Lipase inhibition, Lipid chain length, Lipid-based drug delivery systems, Pharmacokinetic study, Supersaturated lipid-based formulations

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/586c554b-69ed-4396-9283-39b867861958Test

الإتاحة: https://doi.org/10.1016/j.ejps.2024.106765Test
https://portal.findresearcher.sdu.dk/da/publications/586c554b-69ed-4396-9283-39b867861958Test
https://findresearcher.sdu.dk/ws/files/259936926/1-s2.0-S0928098724000769-main.pdfTest

المؤلفون: Zulbeari, Nadina, Hansen, Mads, Morgen, Per, Holm, René

المصدر: Zulbeari , N , Hansen , M , Morgen , P & Holm , R 2024 , ' Impact of drug compounds mechanical/deformation properties on the preparation of nano- and microsuspensions ' , Journal of Drug Delivery Science and Technology , vol. 95 , 105605 . https://doi.org/10.1016/j.jddst.2024.105605Test

مصطلحات موضوعية: Deformation properties, Dual centrifugation, Media milling, Nano- and microsuspensions, Physical stability

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/f5e07cf8-33c0-4649-92fb-3598102cecf9Test

الإتاحة: https://doi.org/10.1016/j.jddst.2024.105605Test
https://portal.findresearcher.sdu.dk/da/publications/f5e07cf8-33c0-4649-92fb-3598102cecf9Test
https://findresearcher.sdu.dk/ws/files/259248626/1-s2.0-S1773224724002740-main.pdfTest

المؤلفون: Paulus, Felix, Bauer-Brandl, Annette, Stappaerts, Jef, Holm, René

المصدر: Paulus , F , Bauer-Brandl , A , Stappaerts , J & Holm , R 2024 , ' Digestion is a critical element for absorption of cinnarizine from supersaturated lipid-based type I formulations ' , European Journal of Pharmaceutical Sciences , vol. 192 , 106634 . https://doi.org/10.1016/j.ejps.2023.106634Test

مصطلحات موضوعية: Drug solubility, Lipase inhibition, Lipid chain length, Lipid-based drug delivery systems, Pharmacokinetic study, Supersaturated lipid-based formulations

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/406f4fbf-a5cf-4b80-875d-39b75b6a905cTest

الإتاحة: https://doi.org/10.1016/j.ejps.2023.106634Test
https://portal.findresearcher.sdu.dk/da/publications/406f4fbf-a5cf-4b80-875d-39b75b6a905cTest
https://findresearcher.sdu.dk/ws/files/246044911/1_s2.0_S0928098723002646_main.pdfTest

المؤلفون: Rasmussen, Asbjørn Jaensch, Pedersen, Maria, Griffin, Brendan T, Holm, René, Nielsen, Carsten Uhd

المصدر: Rasmussen , A J , Pedersen , M , Griffin , B T , Holm , R & Nielsen , C U 2024 , ' Digestion of surfactants does not affect their ability to inhibit P-gp-mediated transport in vitro ' , International Journal of Pharmaceutics , vol. 656 , pp. 124120 . https://doi.org/10.1016/j.ijpharm.2024.124120Test

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/f7bc8298-0ca7-453f-9c78-2bf566f916c6Test

الإتاحة: https://doi.org/10.1016/j.ijpharm.2024.124120Test
https://portal.findresearcher.sdu.dk/da/publications/f7bc8298-0ca7-453f-9c78-2bf566f916c6Test
https://findresearcher.sdu.dk/ws/files/259246686/1-s2.0-S0378517324003545-main.pdfTest

المؤلفون: Petersen, Emilie Fynbo, Larsen, Bjarke Strøm, Nielsen, Rasmus Blaaholm, Pijpers, Ils, Versweyveld, Dries, Holm, René, Tho, Ingunn, Snoeys, Jan, Nielsen, Carsten Uhd

المصدر: Petersen , E F , Larsen , B S , Nielsen , R B , Pijpers , I , Versweyveld , D , Holm , R , Tho , I , Snoeys , J & Nielsen , C U 2024 , ' Co-release of paclitaxel and encequidar from amorphous solid dispersions increase oral paclitaxel bioavailability in rats ' , International Journal of Pharmaceutics , vol. 654 , pp. 123965 . https://doi.org/10.1016/j.ijpharm.2024.123965Test

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/e96656f0-9167-449c-af5f-a828833a57aaTest

الإتاحة: https://doi.org/10.1016/j.ijpharm.2024.123965Test
https://portal.findresearcher.sdu.dk/da/publications/e96656f0-9167-449c-af5f-a828833a57aaTest
https://findresearcher.sdu.dk/ws/files/259085261/1-s2.0-S0378517324001996-main.pdfTest

المؤلفون: Ejskjær, Lotte, O'Dwyer, Patrick J., Ryan, Callum D., Holm, René, Kuentz, Martin, Box, Karl J., Griffin, Brendan T.

المصدر: Ejskjær , L , O'Dwyer , P J , Ryan , C D , Holm , R , Kuentz , M , Box , K J & Griffin , B T 2024 , ' Developing an in vitro lipolysis model for real-time analysis of drug concentrations during digestion of lipid-based formulations ' , European Journal of Pharmaceutical Sciences , vol. 194 , 106681 . https://doi.org/10.1016/j.ejps.2023.106681Test

مصطلحات موضوعية: Fenofibrate, In vitro lipolysis, Lipid digestion, Lipid-based formulations

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/3ffcb1a5-c401-4e7b-a002-d36e3a27c325Test

الإتاحة: https://doi.org/10.1016/j.ejps.2023.106681Test
https://portal.findresearcher.sdu.dk/da/publications/3ffcb1a5-c401-4e7b-a002-d36e3a27c325Test
https://findresearcher.sdu.dk/ws/files/253604380/1-s2.0-S0928098723003093-main.pdfTest

المؤلفون: Zulbeari, Nadina, Holm, René

المصدر: Zulbeari , N & Holm , R 2024 , ' Is roller milling – the low energy wet bead media milling – a reproducible and robust milling method for formulation investigation of aqueous suspensions? ' , International Journal of Pharmaceutics , vol. 651 , 123733 . https://doi.org/10.1016/j.ijpharm.2023.123733Test

مصطلحات موضوعية: Formulation screening, Long-acting injectables, Nano- and microsuspensions, Physical stability, Reproducibility, Roller milling

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/efc5d98c-dc88-44e5-a746-8c7d77ce0816Test

الإتاحة: https://doi.org/10.1016/j.ijpharm.2023.123733Test
https://portal.findresearcher.sdu.dk/da/publications/efc5d98c-dc88-44e5-a746-8c7d77ce0816Test
https://findresearcher.sdu.dk/ws/files/252955539/1-s2.0-S0378517323011559-main.pdfTest

المؤلفون: Zulbeari, Nadina, Holm, René

المصدر: Journal of Pharmaceutical Sciences ; ISSN 0022-3549

مصطلحات موضوعية: Pharmaceutical Science

الإتاحة: https://doi.org/10.1016/j.xphs.2024.04.015Test
https://api.elsevier.com/content/article/PII:S0022354924001400?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0022354924001400?httpAccept=text/plainTest

المؤلفون: Murray, Jack D., Lange, Justus J., Bennett-Lenane, Harriet, Holm, René, Kuentz, Martin, O'Dwyer, Patrick J., Griffin, Brendan T.

مصطلحات موضوعية: Machine learning, Artificial intelligence, Computational pharmaceutics, Drug formulation, Data-driven modelling, Property prediction

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

العلاقة: info:eu-repo/grantAgreement/EC/H2020::MSCA-ITN-EID/955756/EU/A fully integrated, animal-free, end-to-end modelling approach to oral drug product development/InPharma; 106562; Murray, J. D., Lange, J. J., Bennett-Lenane, H., Holm, R., Kuentz, M., O'Dwyer, P. J. and Griffin, B. T. (2023) 'Advancing algorithmic drug product development: Recommendations for machine learning approaches in drug formulation', European Journal of Pharmaceutical Sciences, 191, 106562 (13pp). doi:10.1016/j.ejps.2023.106562; 13; European Journal of Pharmaceutical Sciences; https://hdl.handle.net/10468/15055Test; 191

الإتاحة: https://doi.org/10.1016/j.ejps.2023.106562Test
https://hdl.handle.net/10468/15055Test

المؤلفون: Reppas, Christos, Kuentz, Martin, Bauer-Brandl, Annette, Carlert, Sara, Dallmann, André, Dietrich, Shirin, Dressman, Jennifer, Ejskjaer, Lotte, Frechen, Sebastian, Guidetti, Matteo, Holm, René, Holzem, Florentin Lukas, Karlsson, Εva, Kostewicz, Edmund, Panbachi, Shaida, Paulus, Felix, Senniksen, Malte Bøgh, Stillhart, Cordula, Turner, David B., Vertzoni, Maria, Vrenken, Paul, Zöller, Laurin, Griffin, Brendan T., O'Dwyer, Patrick J.

مصطلحات موضوعية: Enabling formulations In vitroIn silico, PBBMrDCS, Computational, Amorphous solid dispersions, Lipid-based formulations, Cyclodextrins, Co-crystals, Salts

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

العلاقة: info:eu-repo/grantAgreement/EC/H2020::MSCA-ITN-EID/955756/EU/A fully integrated, animal-free, end-to-end modelling approach to oral drug product development/InPharma; 106505; Reppas, C., Kuentz, M., Bauer-Brandl, A., Carlert, S., Dallmann, A., Dietrich, S., Dressman, J., Ejskjaer, L., Frechen, S., Guidetti, M., Holm, R., Holzem, F. L., Karlsson, E., Kostewicz, E., Panbachi, S., Paulus, F., Senniksen, M. B., Stillhart, C., Turner, D. B., Vertzoni, M., Vrenken, P., Zöller, L., Griffin, B. T. and O'Dwyer, P. J. (2023) 'Leveraging the use of in vitro and computational methods to support the development of enabling oral drug products: An InPharma commentary', European Journal of Pharmaceutical Sciences, 188, 106505 (22pp). doi:10.1016/j.ejps.2023.106505; 22; European Journal of Pharmaceutical Sciences; https://hdl.handle.net/10468/15056Test; 188

الإتاحة: https://doi.org/10.1016/j.ejps.2023.106505Test
https://hdl.handle.net/10468/15056Test