المؤلفون: Pathak, Pragya, Alexander, Krista K, Helton, Leah G, Kentros, Michalis, LeClair, Timothy J, Zhang, Xiaojuan, Ho, Franz Y, Moore, Timothy T, Hall, Scotty, Guaitoli, Giambattista, Gloeckner, Christian Johannes, Kortholt, Arjan, Rideout, Hardy, Kennedy, Eileen J

المصدر: Pathak , P , Alexander , K K , Helton , L G , Kentros , M , LeClair , T J , Zhang , X , Ho , F Y , Moore , T T , Hall , S , Guaitoli , G , Gloeckner , C J , Kortholt , A , Rideout , H & Kennedy , E J 2023 , ' Doubly Constrained C-terminal of Roc (COR) Domain-Derived Peptides Inhibit Leucine-Rich Repeat Kinase 2 (LRRK2) Dimerization ' , ACS chemical neuroscience , vol. 14 , no. 11 , 00259 , pp. 1971-1980 . https://doi.org/10.1021/acschemneuro.3c00259Test

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/8b0f169c-49a7-4d9a-a76d-669929bf4f40Test

الإتاحة: https://doi.org/10.1021/acschemneuro.3c00259Test
https://hdl.handle.net/11370/8b0f169c-49a7-4d9a-a76d-669929bf4f40Test
https://research.rug.nl/en/publications/8b0f169c-49a7-4d9a-a76d-669929bf4f40Test
https://pure.rug.nl/ws/files/689526179/acschemneuro.3c00259.pdfTest

المؤلفون: Marchand, Antoine, Sarchione, Alessia, Athanasopoulos, Panagiotis, Roy, Hélène Bauderlique-Le, Goveas, Liesel, Romain, MAGNEZ, Drouyer, Matthieu, Emanuele, Marco, Ho, Franz Y., Liberelle, Maxime, Melnyk, Patricia, Nicolas, LEBEGUE, Thuru, Xavier, Nichols, R. Jeremy, Greggio, Elisa, kortholt, arjan, Galli, Thierry, chartier-harlin, marie-christine, Taymans, Jean-Marc

المصدر: Marchand , A , Sarchione , A , Athanasopoulos , P , Roy , H B-L , Goveas , L , Romain , MAGNEZ , Drouyer , M , Emanuele , M , Ho , F Y , Liberelle , M , Melnyk , P , Nicolas , LEBEGUE , Thuru , X , Nichols , R J , Greggio , E , kortholt , A , Galli , T , chartier-harlin , M & Taymans , J-M 2022 , ' A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively ' , ....

مصطلحات موضوعية: LRRK2, phosphorylation, Parkinson's disease, RABs, lysosome

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/21822a2d-14e9-493b-878b-bdcb2b796498Test

الإتاحة: https://doi.org/10.3390/cells11061018Test
https://hdl.handle.net/11370/21822a2d-14e9-493b-878b-bdcb2b796498Test
https://research.rug.nl/en/publications/21822a2d-14e9-493b-878b-bdcb2b796498Test
https://pure.rug.nl/ws/files/209076372/cells_11_01018.pdfTest
https://www.mdpi.com/2073-4409/11/6/1018Test

المؤلفون: Cogo, Susanna, Ho, Franz Y, Tosoni, Elena, Tomkins, James E, Tessari, Isabella, Iannotta, Lucia, Montine, Thomas J, Manzoni, Claudia, Lewis, Patrick A, Bubacco, Luigi, Chartier Harlin, Marie-Christine, Taymans, Jean-Marc, Kortholt, Arjan, Nichols, Jeremy, Cendron, Laura, Civiero, Laura, Greggio, Elisa

المصدر: Cogo , S , Ho , F Y , Tosoni , E , Tomkins , J E , Tessari , I , Iannotta , L , Montine , T J , Manzoni , C , Lewis , P A , Bubacco , L , Chartier Harlin , M-C , Taymans , J-M , Kortholt , A , Nichols , J , Cendron , L , Civiero , L & Greggio , E 2022 , ' The Roc domain of LRRK2 as a hub for protein-protein interactions : a focus on PAK6 and its impact on RAB phosphorylation ' , ....

مصطلحات موضوعية: Parkinson's disease, LRKK2, GTPase, protein-protein interactions, PAK6, 14-3-3 proteins

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/d8970e59-0dd3-4ad8-93ba-e327d13e9d13Test

الإتاحة: https://doi.org/10.1016/j.brainres.2022.147781Test
https://hdl.handle.net/11370/d8970e59-0dd3-4ad8-93ba-e327d13e9d13Test
https://research.rug.nl/en/publications/d8970e59-0dd3-4ad8-93ba-e327d13e9d13Test
https://pure.rug.nl/ws/files/856546636/1-s2.0-S0006899322000051-main.pdfTest

المؤلفون: Cogo, Susanna, Ho, Franz Y, Tosoni, Elena, Tomkins, James E, Tessari, Isabella, Iannotta, Lucia, Montine, Thomas J, Manzoni, Claudia, Lewis, Patrick A, Bubacco, Luigi, Chartier Harlin, Marie-Christine, Taymans, Jean-Marc, Kortholt, Arjan, Nichols, Jeremy, Cendron, Laura, Civiero, Laura, Greggio, Elisa

المصدر: Brain Research , 1778 , Article 147781. (2022)

مصطلحات موضوعية: 14-3-3 proteins, GTPase, LRRK2, PAK6, Parkinson’s disease, Protein-protein interactions, GTP Phosphohydrolases, Humans, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Parkinson Disease, Phosphorylation, Protein Interaction Domains and Motifs, p21-Activated Kinases

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/10153665/1/Lewis_Lewis_1_s2.0_S0006899322000051_main.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10153665Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/10153665/1/Lewis_Lewis_1_s2.0_S0006899322000051_main.pdfTest
https://discovery.ucl.ac.uk/id/eprint/10153665Test/

المؤلفون: Gilsbach, Bernd K., Ho, Franz Y., Riebenbauer, Benjamin, Zhang, Xiaojuan, Guaitoli, Giambattista, Kortholt, Arjan, Gloeckner, Christian Johannes

الإتاحة: https://doi.org/10.7554/elife.91083.2.sa3Test

المؤلفون: Gilsbach, Bernd K., Ho, Franz Y., Riebenbauer, Benjamin, Zhang, Xiaojuan, Guaitoli, Giambattista, Kortholt, Arjan, Gloeckner, Christian Johannes

الإتاحة: https://doi.org/10.7554/elife.91083Test
https://elifesciences.org/reviewed-preprints/91083v2/pdfTest

المؤلفون: Helton, Leah G., Soliman, Ahmed, von Zweydorf, Felix, Kentros, Michalis, Manschwetus, Jascha T., Hall, Scotty, Gilsbach, Bernd, Ho, Franz Y., Athanasopoulos, Panagiotis S., Singh, Ranjan K., LeClair, Timothy J., Versées, Wim, Raimondi, Francesco, Herberg, Friedrich W., Gloeckner, Christian Johannes, Rideout, Hardy, Kortholt, Arjan, Kennedy, Eileen J.

المساهمون: Helton, Leah G., Soliman, Ahmed, von Zweydorf, Felix, Kentros, Michali, Manschwetus, Jascha T., Hall, Scotty, Gilsbach, Bernd, Ho, Franz Y., Athanasopoulos, Panagiotis S., Singh, Ranjan K., Leclair, Timothy J., Versées, Wim, Raimondi, Francesco, Herberg, Friedrich W., Gloeckner, Christian Johanne, Rideout, Hardy, Kortholt, Arjan, Kennedy, Eileen J.

مصطلحات موضوعية: Allosteric Regulation, Amino Acid Sequence, Apoptosi, Dimerization, Enzyme Activation, Enzyme Inhibitor, Human, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Neuron, Parkinson Disease, Peptide, Protein Binding, Reactive Oxygen Specie, Signal Transduction, Settore BIO/11 - Biologia Molecolare

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34496561; info:eu-repo/semantics/altIdentifier/wos/WOS:000726639500003; volume:16; issue:11; firstpage:2326; lastpage:2338; numberofpages:13; journal:ACS CHEMICAL BIOLOGY; http://hdl.handle.net/11384/113486Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85115614562

الإتاحة: https://doi.org/10.1021/acschembio.1c00487Test
http://hdl.handle.net/11384/113486Test

المؤلفون: Helton, Leah G, Soliman, Ahmed, LeClair, Timothy J, Versées, Wim, Raimondi, Francesco, Herberg, Friedrich W, Gloeckner, Christian Johannes, Rideout, Hardy, Kortholt, Arjan, Kennedy, Eileen J, von Zweydorf, Felix, Kentros, Michalis, Manschwetus, Jascha T, Hall, Scotty, Gilsbach, Bernd, Ho, Franz Y, Athanasopoulos, Panagiotis S, Singh, Ranjan K

المصدر: ACS chemical biology 16(11), 2326 - 2338 (2021). doi:10.1021/acschembio.1c00487

مصطلحات موضوعية: info:eu-repo/classification/ddc/540, Allosteric Regulation, Amino Acid Sequence, Apoptosis: drug effects, Dimerization, Enzyme Activation, Enzyme Inhibitors: pharmacology, Humans, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2: antagonists & inhibitors, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2: metabolism, Neurons: drug effects, Parkinson Disease: enzymology, Parkinson Disease: pathology, Peptides: chemistry, Peptides: pharmacology, Protein Binding, Reactive Oxygen Species: metabolism, Signal Transduction: drug effects

جغرافية الموضوع: DE

العلاقة: info:eu-repo/semantics/altIdentifier/issn/1554-8929; info:eu-repo/semantics/altIdentifier/issn/1554-8937; info:eu-repo/semantics/altIdentifier/pmid/pmid:34496561; https://pub.dzne.de/record/162930Test; https://pub.dzne.de/search?p=id:%22DZNE-2021-01582%22Test

الإتاحة: https://doi.org/10.1021/acschembio.1c00487Test
https://pub.dzne.de/record/162930Test
https://pub.dzne.de/search?p=id:%22DZNE-2021-01582%22Test

المؤلفون: Gilsbach, Bernd K., Ho, Franz Y., Riebenbauer, Benjamin, Zhang, Xiaojuan, Guaitoli, Giambattista, Kortholt, Arjan, Gloeckner, Christian Johannes

الإتاحة: https://doi.org/10.7554/elife.91083.1.sa3Test

المؤلفون: Gilsbach, Bernd K., Ho, Franz Y., Riebenbauer, Benjamin, Zhang, Xiaojuan, Guaitoli, Giambattista, Kortholt, Arjan, Gloeckner, Christian Johannes

الإتاحة: https://doi.org/10.7554/elife.91083.1Test
https://elifesciences.org/reviewed-preprints/91083v1/pdfTest