المؤلفون: Kishimoto, Shinji, Hara, Kodai, Hashimoto, Hiroshi, Hirayama, Yuichiro, Champagne, Pier Alexandre, Houk, Kendall N, Tang, Yi, Watanabe, Kenji

المصدر: Nature communications. 9(1)

مصطلحات موضوعية: Escherichia coli, Aspergillus nidulans, Carbon Dioxide, Zinc, Methylamines, Isocyanates, Alkaloids, Hydroxyquinolines, Quinolones, Fungal Proteins, Recombinant Proteins, Crystallography, X-Ray, Cloning, Molecular, Gene Expression, Binding Sites, Protein Binding, Substrate Specificity, Cyclization, Kinetics, Genetic Vectors, Models, Molecular, Biosynthetic Pathways, Protein Interaction Domains and Motifs, Protein Conformation, alpha-Helical, Hemocyanins, Cloning, Molecular, Crystallography, X-Ray, Models, Protein Conformation, alpha-Helical

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/31b4n6wwTest

المؤلفون: Zou, Yi, Garcia-Borràs, Marc, Tang, Mancheng C, Hirayama, Yuichiro, Li, Dehai H, Li, Li, Watanabe, Kenji, Houk, KN, Tang, Yi

المصدر: Nature Chemical Biology. 13(3)

مصطلحات موضوعية: Biological Sciences, Organic Chemistry, Chemical Sciences, Rare Diseases, Orphan Drug, Alkaloids, Aspergillus nidulans, Biocatalysis, Cations, Epoxy Compounds, Hydro-Lyases, Molecular Structure, Penicillium, Quantum Theory, Quinolones, Medicinal and Biomolecular Chemistry, Biochemistry and Cell Biology, Biochemistry & Molecular Biology, Biochemistry and cell biology, Medicinal and biomolecular chemistry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8m39m4tbTest

المؤلفون: Kawanishi Masanobu, Shimohara Chiaki, Oda Yoshimitsu, Hisatomi Yuuta, Tsunematsu Yuta, Sato Michio, Hirayama Yuichiro, Miyoshi Noriyuki, Iwashita Yuji, Yoshikawa Yuko, Sugimura Haruhiko, Mutoh Michihiro, Ishikawa Hideki, Wakabayashi Keiji, Yagi Takashi, Watanabe Kenji

مصطلحات موضوعية: Colibactin, Genotyping, Genotoxicity

وصف الملف: application/pdf

العلاقة: https://doi.org/10.1186/s41021-020-00149-zTest; https://genesenvironment.biomedcentral.com/articles/10.1186/s41021-020-00149-zTest; https://omu.repo.nii.ac.jp/?action=repository_uri&item_id=11770Test; http://hdl.handle.net/10466/00016880Test; Genes and Environment. 2020, 42,(Article number: 12), P.1-6; Genes and Environment, 42(Article number: 12), 1-6(2020-03-11); https://omu.repo.nii.ac.jp/?action=repository_action_common_download&item_id=11770&item_no=1&attribute_id=19&file_no=1Test

الإتاحة: https://doi.org/10.1186/s41021-020-00149-zTest
http://hdl.handle.net/10466/00016880Test
https://omu.repo.nii.ac.jp/?action=repository_uri&item_id=11770Test
https://omu.repo.nii.ac.jp/?action=repository_action_common_download&item_id=11770&item_no=1&attribute_id=19&file_no=1Test

المؤلفون: Kawanishi, Masanobu, Shimohara, Chiaki, Oda, Yoshimitsu, Hisatomi, Yuuta, Tsunematsu, Yuta, Sato, Michio, Hirayama, Yuichiro, Miyoshi, Noriyuki, Iwashita, Yuji, Yoshikawa, Yuko, Sugimura, Haruhiko, Mutoh, Michihiro, Ishikawa, Hideki, Wakabayashi, Keiji, Yagi, Takashi, Watanabe, Kenji

المساهمون: Japan Society for the Promotion of Science, Japan Agency for Medical Research and Development, Ministry of Education, Culture, Sports, Science and Technology, Takeda Pharmaceutical Company, Institution of Fermentation at Osaka, Princess Takamatsu Cancer Research Fund, Yakult Bio-Science Foundation

المصدر: Genes and Environment ; volume 42, issue 1 ; ISSN 1880-7062

مصطلحات موضوعية: Environmental Science (miscellaneous), Genetics, Social Psychology

الإتاحة: https://doi.org/10.1186/s41021-020-00149-zTest

المؤلفون: Tajima, Yuya, Toyoda, Takeshi, Hirayama, Yuichiro, Matsushita, Kohei, Yamada, Takanori, Ogawa, Kumiko, Watanabe, Kenji, Takamura-Enya, Takeji, Totsuka, Yukari, Wakabayashi, Keiji, Miyoshi, Noriyuki

المصدر: Chemical Research in Toxicology ; volume 33, issue 12, page 3065-3065 ; ISSN 0893-228X 1520-5010

مصطلحات موضوعية: Toxicology, General Medicine

الإتاحة: https://doi.org/10.1021/acs.chemrestox.0c00469Test

المؤلفون: Khojasteh, S Cyrus, Argikar, Upendra A, Driscoll, James P, Heck, Carley JS, King, Lloyd, Jackson, Klarissa D, Jian, Wenying, Kalgutkar, Amit S, Miller, Grover P, Kramlinger, Valerie, Rietjens, Ivonne MCM, Teitelbaum, Aaron M, Wang, Kai, Wei, Cong, Johnson, Benjamin M, Shu, Yue-Zhong, Zhuo, Xiaoliang, Meanwell, Nicholas A, Cerny, Matthew A, Obach, R Scott, Sharma, Raman, Spracklin, Douglas K, Walker, Gregory S, Goracci, Laura, Desantis, Jenny, Valeri, Aurora, Castellani, Beatrice, Eleuteri, Michela, Cruciani, Gabriele, Lall, Manjinder S, Bassyouni, Asser, Bradow, James, Brown, Maria, Bundesmann, Mark, Chen, Jinshan, Ciszewski, Gregory, Hagen, Anne E, Hyek, Dennis, Jenkinson, Stephen, Liu, Bo, Pan, Senliang, Reilly, Usa, Sach, Neal, Smaltz, Daniel J, Starr, Jeremy, Wagenaar, Melissa, de Bruyn Kops, Christina, Sicho, Martin, Mazzolari, Angelica, Kirchmair, Johannes, Korprasertthaworn, Porntipa, Chau, Nuy, Nair, Pramod C, Rowland, Andrew, Miners, John O, Wrobleski, Stephen T, Moslin, Ryan, Lin, Shuqun, Zhang, Yanlei, Spergel, Steven, Kempson, James, Tokarski, John S, Strnad, Joann, Zupa-Fernandez, Adriana, Cheng, Lihong, Shuster, David, Gillooly, Kathleen, Yang, Xiaoxia, Heimrich, Elizabeth, McIntyre, Kim W, Chaudhry, Charu, Khan, Javed, Ruzanov, Max, Tredup, Jeffrey, Mulligan, Dawn, Xie, Dianlin, Sun, Huadong, Huang, Christine, D'Arienzo, Celia, Aranibar, Nelly, Chiney, Manoj, Chimalakonda, Anjaneya, Pitts, William J, Lombardo, Louis, Carter, Percy H, Burke, James R, Weinstein, David S, Li, Jing, Liu, Ju, Enders, Jennifer, Arciprete, Michael, Tran, Chris, Aluri, Krishna, Guan, Li-Hua, O'Shea, Jonathan, Bisbe, Anna, Charisse, Klaus, Zlatev, Ivan, Najarian, Diana, Xu, Yuanxin, Kim, Jaeah, El Zahar, Noha M, Bartlett, Michael G, Katyayan, Kishore, Yi, Ping, Monk, Scott, Cassidy, Kenneth, Takahashi, Ryan H, Grandner, Jessica M, Bobba, Sudheer, Liu, Yanzhou, Beroza, Paul, Zhang, Donglu, Ma, Shuguang, Post, Noah, Yu, Rosie, Greenlee, Sarah, Gaus, Hans, Hurh, Eunju, Matson, John, Wang, Yanfeng, Tajima, Yuya, Toyoda, Takeshi, Hirayama, Yuichiro, Matsushita, Kohei, Yamada, Takanori, Ogawa, Kumiko, Watanabe, Kenji, Takamura-Enya, Takeji, Totsuka, Yukari, Wakabayashi, Keiji, Miyoshi, Noriyuki, Zhang, Jiayin, Chan, Chi-Kong, Ham, Yat-Hing, Chan, Wan, Schleiff, Mary Alexandra, Flynn, Noah R, Payakachat, Sasin, Schleiff, Benjamin Mark, Pinson, Anna O, Province, Dennis W, Swamidass, S Joshua, Boysen, Gunnar, Nardone-White, Dasean T, Bissada, Jennifer E, Abouda, Arsany A, Zhang, Zhuming, Connolly, Peter J, Lim, Heng Keang, Pande, Vineet, Meerpoel, Lieven, Teleha, Christopher, Branch, Jonathan R, Ondrus, Janine, Hickson, Ian, Bush, Tammy, Luistro, Leopoldo, Packman, Kathryn, Bischoff, James R, Ibrahim, Salam, Parrett, Christopher, Chong, Yolanda, Gottardis, Marco M, Bignan, Gilles, Mulder, Teresa, Bobba, Sudder, Johnson, Kevin M, Wang, Wei, Zhang, Chenghong, Cai, Jingwei, Choo, Edna F, Crawford, James J, Landry, Matthew L, Chen, Huifen, Kenny, Jane R, Lee, Wendy, Young, Wendy B, Geib, Timon, Thulasingam, Madhuranayaki, Haeggstrom, Jesper Z, Sleno, Lekha, Monroe, James J, Tanis, Keith Q, Podtelezhnikov, Alexei A, Nguyen, Truyen, Machotka, Sam V, Lynch, Donna, Evers, Raymond, Palamanda, Jairam, Miller, Randy R, Pippert, Todd, Cabalu, Tamara D, Johnson, Timothy E, Aslamkhan, Amy G, Kang, Wen, Tamburino, Alex M, Mitra, Kaushik, Agrawal, Nancy GB, Sistare, Frank D

المصدر: Drug Metabolism Reviews 53 (2021) 3
Drug Metabolism Reviews, 53(3), 384-433

مصطلحات موضوعية: METABOLISM, Toxicology, 030226 pharmacology & pharmacy, 03 medical and health sciences, nonp450 enzymes, 0302 clinical medicine, p450 enzymes, Biotransformation, INTRINSIC CLEARANCE, Political science, MASS-BALANCE, Humans, Pharmacology (medical), Pharmacology & Pharmacy, P450 Enzymes, General Pharmacology, Toxicology and Pharmaceutics, ANTISENSE OLIGONUCLEOTIDE, Toxicologie, VLAG, ARISTOLOCHIC ACID, Drug metabolism, Science & Technology, WIMEK, bioactivation, IDENTIFICATION, Year in review, IN-VITRO, NONHEPATOTOXIC DRUGS, Drug metabolizing enzymes, Drug development, 030220 oncology & carcinogenesis, COVALENT BINDING DATA, Engineering ethics, biotransformation, LIVER-MICROSOMES, Life Sciences & Biomedicine

وصف الملف: application/pdf; Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a22a3073b1b8be7c5621703d8a65f67Test
https://doi.org/10.1080/03602532.2021.1916028Test

المؤلفون: Hirayama, Yuichiro, Sato, Michio, Watanabe, Kenji

المساهمون: Takeda Science Foundation, Ministry of Education, Culture, Sports, Science and Technology, Yasuda Memorial Medical Foundation, Japan Agency for Medical Research and Development, Kobayashi Foundation for Cancer Research, Princess Takamatsu Cancer Research Fund, Japan Society for the Promotion of Science, Yakult Bio-Science Foundation, Institution of Fermentation, Osaka, SECOM Science and Technology

المصدر: Biochemistry ; volume 61, issue 24, page 2782-2790 ; ISSN 0006-2960 1520-4995

مصطلحات موضوعية: Biochemistry

الإتاحة: https://doi.org/10.1021/acs.biochem.2c00229Test

المؤلفون: Hirayama, Yuichiro, Yamagishi, Kota, Suzuki, Tomohiro, Kawagishi, Hirokazu, Kita, Masaki, Kigoshi, Hideo

المساهمون: JSPS, MEXT, PRESTO, JST, Naito Foundation

المصدر: Bioorganic & Medicinal Chemistry ; volume 24, issue 12, page 2809-2814 ; ISSN 0968-0896

مصطلحات موضوعية: Organic Chemistry, Clinical Biochemistry, Drug Discovery, Pharmaceutical Science, Molecular Biology, Molecular Medicine, Biochemistry

الإتاحة: https://doi.org/10.1016/j.bmc.2016.04.049Test
https://api.elsevier.com/content/article/PII:S0968089616302929?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0968089616302929?httpAccept=text/plainTest

المؤلفون: Tsunematsu, Yuta, Hirayama, Yuichiro, Masuya, Takahiro, Watanabe, Kenji

المصدر: Comprehensive Natural Products III ; page 479-505

الإتاحة: https://doi.org/10.1016/b978-0-12-409547-2.14637-2Test
https://api.elsevier.com/content/article/PII:B9780124095472146372?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:B9780124095472146372?httpAccept=text/plainTest

المؤلفون: 平山, 裕一郎, HIRAYAMA, Yuichiro

وصف الملف: application/pdf

الوصول الحر: https://ndlsearch.ndl.go.jp/books/R100000039-I8977299Test

Degree: 博士（理学）/ Doctor of Philosophy in Science -- 筑波大学 (University of Tsukuba)