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1دورية أكاديمية
المؤلفون: Miller, Duncan C, Reuillon, Tristan, Molyneux, Lauren, Blackburn, Timothy, Cook, Simon J, Edwards, Noel, Endicott, Jane A, Golding, Bernard T, Griffin, Roger J, Hardcastle, Ian, Harnor, Suzannah J, Heptinstall, Amy, Lochhead, Pamela, Martin, Mathew P, Martin, Nick C, Myers, Stephanie, Newell, David R, Noble, Richard A, Phillips, Nicole, Rigoreau, Laurent, Thomas, Huw, Tucker, Julie A, Wang, Lan-Zhen, Waring, Michael J, Wong, Ai-Ching, Wedge, Stephen R, Noble, Martin E, Cano, Celine
مصطلحات موضوعية: Chemistry
وصف الملف: application/pdf
العلاقة: http://sure.sunderland.ac.uk/id/eprint/14709/8/acs.jmedchem.1c01756.pdfTest; Miller, Duncan C , Reuillon, Tristan , Molyneux, Lauren , Blackburn, Timothy , Cook, Simon J , Edwards, Noel , Endicott, Jane A , Golding, Bernard T , Griffin, Roger J , Hardcastle, Ian , Harnor, Suzannah J , Heptinstall, Amy , Lochhead, Pamela , Martin, Mathew P , Martin, Nick C , Myers, Stephanie , Newell, David R , Noble, Richard A , Phillips, Nicole , Rigoreau, Laurent , Thomas, Huw , Tucker, Julie A , Wang, Lan-Zhen , Waring, Michael J , Wong, Ai-Ching , Wedge, Stephen R , Noble, Martin E and Cano, Celine (2022) Parallel Optimisation of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain Inhibitor. Journal of Medicinal Chemistry, 65 (9). pp. 6513-6540. ISSN 0022-2623
الإتاحة: http://sure.sunderland.ac.uk/id/eprint/14709Test/
http://sure.sunderland.ac.uk/id/eprint/14709/8/acs.jmedchem.1c01756.pdfTest -
2دورية أكاديمية
المؤلفون: Davison, Gemma, Martin, Mathew P., Turberville, Shannon, Dormen, Selma, Heath, Richard, Heptinstall, Amy B., Lawson, Marie, Miller, Duncan C., Ng, Yi Min, Sanderson, James N., Hope, Ian, Wood, Daniel J., Cano, Céline, Endicott, Jane A., Hardcastle, Ian R., Noble, Martin E. M., Waring, Michael J.
المساهمون: Medical Research Council, Newcastle University, Cancer Research UK
المصدر: Journal of Medicinal Chemistry ; volume 65, issue 22, page 15416-15432 ; ISSN 0022-2623 1520-4804
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3دورية أكاديمية
المؤلفون: Picazo, Edwige M. H., Heptinstall, Amy B., Wilson, David M., Cano, Céline, Golding, Bernard T., Waring, Michael J.
المساهمون: AstraZeneca, Cancer Research UK
المصدر: Journal of Heterocyclic Chemistry ; volume 58, issue 4, page 947-951 ; ISSN 0022-152X 1943-5193
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4دورية أكاديمية
المؤلفون: Tucker, Julie Ann, Myers, Stephanie M., Miller, Duncan C., Molyneux, Lauren, Arasta, Mercedes, Bawn, Ruth H., Blackburn, Timothy J., Cook, Simon J., Edwards, Noel, Endicott, Jane A., Golding, Bernard T., Griffin, Roger J., Hammonds, Tim, Hardcastle, Ian R., Harnor, Suzannah J., Heptinstall, Amy B., Lochhead, Pamela A., Martin, Mathew P., Martin, Nick C., Newell, David R., Owen, Paul J., Pang, Leon C., Reuillon, Tristan, Rigoreau, Laurent J.M., Thomas, Huw D., Wang, Lan-Zhen, Wong, Ai-Ching, Noble, Martin E.M., Wedge, Stephen R., Cano, Celine
وصف الملف: text
العلاقة: https://eprints.whiterose.ac.uk/148098/1/ERK5LeadIDPaper_EurJMedChem_2019_04_29.docxTest; Tucker, Julie Ann orcid.org/0000-0002-6119-676X , Myers, Stephanie M., Miller, Duncan C. et al. (27 more authors) (2019) Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4. European Journal of Medicinal Chemistry. pp. 530-543. ISSN 0223-5234
الإتاحة: https://doi.org/10.1016/j.ejmech.2019.05.057Test
https://eprints.whiterose.ac.uk/148098Test/
https://eprints.whiterose.ac.uk/148098/1/ERK5LeadIDPaper_EurJMedChem_2019_04_29.docxTest -
5دورية أكاديمية
المؤلفون: Miller, Duncan C., Martin, Mathew P., Adhikari, Santosh, Brennan, Alfie, Endicott, Jane A., Golding, Bernard T., Hardcastle, Ian R., Heptinstall, Amy, Hobson, Stephen, Jennings, Claire, Molyneux, Lauren, Ng, Yvonne, Wedge, Stephen R., Noble, Martin E. M., Cano, Celine
المساهمون: Cancer Research UK
المصدر: Organic & Biomolecular Chemistry ; volume 16, issue 11, page 1843-1850 ; ISSN 1477-0520 1477-0539
الإتاحة: https://doi.org/10.1039/c8ob00099aTest
http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB00099ATest -
6
المؤلفون: Miller, Duncan C., Reuillon, Tristan, Molyneux, Lauren, Blackburn, Timothy J., Cook, Simon, Edwards, Noel, Endicott, Jane A., Golding, Bernard T., Griffin, Roger J., Hardcastle, Ian R., Heptinstall, Amy B., Lochhead, Pamela, Martin, Mathew P., Martin, Nick, Myers, Stephanie M., Newell, David R., Noble, Richard, Rigoreau, Laurent J.M., Thomas, Huw, Tucker, Julie Ann, Wang, Lan-Zhen, Waring, Michael J., Wong, Ai-Ching, Wedge, Stephen, Noble, Martin, Cano, Celine
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::643876374a98b92971005d5d769a4162Test
https://eprints.whiterose.ac.uk/185363/3/acs.jmedchem.1c01756.pdfTest -
7دورية أكاديمية
المؤلفون: Moschen, Alexander R., Sammy, Yossi, Marjenberg, Zoe, Heptinstall, Amy B., Pooley, Nick, Marczewska, Agnieszka M.
المصدر: Current Oncology Reports ; volume 24, issue 7, page 861-874 ; ISSN 1523-3790 1534-6269
مصطلحات موضوعية: Oncology
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8
المؤلفون: Al-Khawaldeh, Islam, Alyassiri, Mohammed, Aldred, Greg, Basmadjian, Christine, Bordoni, Cinzia, Harnor, Suzannah J., Heptinstall, Amy B., Hobson, Stephen, Jennings, Claire, Khalifa, Shaimaa, Lebraud, Honorine, Martin, Mathew P., Miller, Duncan C, Shrives, Harry, De Souza, Joao, Stewart, Hannah, Temple, Max J, Thomas, Huw, Totobenazara, Jane, Tucker, Julie Ann, Tudhope, Susan, Wang, Lan-Zhen, Bronowska, Agnieszka, Cano, Celine, Endicott, Jane A., Golding, Bernard, Hardcastle, Ian R., Hickson, Ian, Wedge, Stephen, Willmore, Elaine, Noble, Martin E. M., Waring, Michael J.
وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::0d0425a07b4fd1c06ab32621f25fa4abTest
https://eprints.whiterose.ac.uk/175696/1/Revised_Manuscript_2_.docxTest -
9دورية أكاديمية
المؤلفون: Al-Khawaldeh, Islam, Jennings, Claire, Al Yasiri, Mohammed J., Aldred, Gregory G, Basmadjian, Christine, Bordoni, Cinzia, Harnor, Suzannah J, Heptinstall, Amy B., Hobson, Stephen J, Khalifa, Shaimaa, Lebraud, Honorine, Martin, Mathew P., Miller, Duncan C., Shrives, Harry J, de Souza, Joao V., Stewart, Hannah L, Temple, Max, Thomas, Huw D, Totobenazara, Jane, Tucker, Julie A, Tudhope, Susan J, Wang, Lan Z, Bronowska, Agnieszka K, Cano, Celine, Endicott, Jane A, Golding, Bernard T., Hardcastle, Ian R., Hickson, Ian, Wedge, Stephen R, Willmore, Elaine, Noble, Martin E. M, Waring, Michael J
المصدر: Al-Khawaldeh , I , Jennings , C , Al Yasiri , M J , Aldred , G G , Basmadjian , C , Bordoni , C , Harnor , S J , Heptinstall , A B , Hobson , S J , Khalifa , S , Lebraud , H , Martin , M P , Miller , D C , Shrives , H J , de Souza , J V , Stewart , H L , Temple , M , Thomas , H D , Totobenazara , J , Tucker , J A , Tudhope , S J , ....
الإتاحة: https://doi.org/10.1021/acs.jmedchem.0c01249Test
https://research.tees.ac.uk/en/publications/118fc0ec-89ff-480f-a90c-13b4ade60717Test -
10دورية أكاديمية
المؤلفون: Miller, Duncan C., Reuillon, Tristan, Molyneux, Lauren, Blackburn, Timothy, Cook, Simon J., Edwards, Noel, Endicott, Jane A., Golding, Bernard T., Griffin, Roger J., Hardcastle, Ian, Harnor, Suzannah J., Heptinstall, Amy, Lochhead, Pamela, Martin, Mathew P., Martin, Nick C., Myers, Stephanie, Newell, David R., Noble, Richard A., Phillips, Nicole, Rigoreau, Laurent
المصدر: Journal of Medicinal Chemistry; 5/12/2022, Vol. 65 Issue 9, p6513-6540, 28p