دورية أكاديمية
Care after pancreatic resection according to an algorithm for early detection and minimally invasive management of pancreatic fistula versus current practice (PORSCH-trial): design and rationale of a nationwide stepped-wedge cluster-randomized trial
| العنوان: | Care after pancreatic resection according to an algorithm for early detection and minimally invasive management of pancreatic fistula versus current practice (PORSCH-trial): design and rationale of a nationwide stepped-wedge cluster-randomized trial |
|---|---|
| المؤلفون: | Smits, F.J. (F Jasmijn), Henry, A.C. (Anne Claire), Eijck, C.H.J. (Casper) van, Besselink, M.G. (Marc), Busch, O.R.C. (Olivier), Arntz, M. (Mark), Bollen, T.L. (Thomas), Delden, O.M. (Otto) van, Van Den Heuvel, D.A.F., Leij, C. (Christiaan) van der, van Lienden, K.P. (Krijn P.), Moelker, A. (Adriaan), Bonsing, B.A. (Bert), Borel Rinkes, I.H.M. (Inne), Bosscha, K. (Koop), Dam, R. (Ronald) van, Festen, S. (Sebastiaan), Groot Koerkamp, B. (Bas), Harst, E. (Erwin) van der, Hingh, I.H.J.T. (Ignace) de, Kazemier, G. (Geert), Liem, M. (Mike), van der Kolk, B.M. (B Marion), Meijer, V.E. (Vincent) de, Patijn, G.A. (Gijs A.), Roos, D. (Daphne), Schreinemakers, J.M.J. (Jennifer), Wit, F. (Fennie), van Werkhoven, C.H. (C Henri), Molenaar, I.Q. (I. Quintus), Santvoort, H.C. (Hjalmar) van |
| المصدر: | Trials vol. 21 no. 1 |
| سنة النشر: | 2020 |
| المجموعة: | RePub - Publications from Erasmus University, Rotterdam |
| الوصف: | BACKGROUND: Pancreatic resection is a major abdominal operation with 50% risk of postoperative complications. A common complication is pancreatic fistula, which may have severe clinical consequences such as postoperative bleeding, organ failure and death. The objective of this study is to investigate whether implementation of an algorithm for early detection and minimally invasive management of pancreatic fistula may improve outcomes after pancreatic resection. METHODS: This is a nationwide stepped-wedge, cluster-randomized, superiority trial, designed in adherence to the Consolidated Standards of Reporting Trials (CONSORT) guidelines. During a period of 22 months, all Dutch centers performing pancreatic surgery will cross over in a randomized order from current practice to best practice according to the algorithm. This evidence-based and consensus-based algorithm will provide dai |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | http://repub.eur.nl/pub/126954Test; urn:hdl:1765/126954 |
| DOI: | 10.1186/s13063-020-4167-9 |
| الإتاحة: | https://doi.org/10.1186/s13063-020-4167-9Test http://repub.eur.nl/pub/126954Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.720BAC6A |
| قاعدة البيانات: | BASE |
| DOI: | 10.1186/s13063-020-4167-9 |
|---|