نتائج البحث - "Henri, Xhaard"

المساهمون: Divisions of Faculty of Pharmacy, Division of Pharmaceutical Chemistry and Technology, Drug Research Program, Pharmaceutical Design and Discovery group, Veterinary Biosciences, Faculty of Veterinary Medicine, Faculty of Pharmacy, Department of Pharmacology, Jari Yli-Kauhaluoma / Principal Investigator, Computational Adme, Henri Xhaard / Principal Investigator, Division of Pharmaceutical Biosciences, Erik Wallen / Principal Investigator

وصف الملف: application/pdf; fulltext

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7df09711b7611d8344b9ac76de0bc4cTest
http://hdl.handle.net/10138/359559Test

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Expanding the Paradigm of Structure-Based Drug Design: Molecular Dynamics Simulations Support the Development of New Pyridine-Based Protein Kinase C-Targeted Agonists

المؤلفون: Saara Lautala, Riccardo Provenzani, Ilari Tarvainen, Katia Sirna, S. Tuuli Karhu, Evgeni Grazhdankin, Antti K. Lehtinen, Hanan Sa’d, Artturi Koivuniemi, Henri Xhaard, Raimo K. Tuominen, Virpi Talman, Alex Bunker, Jari Yli-Kauhaluoma

المصدر: Journal of Medicinal Chemistry. 66:4588-4602

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b5245c1c32703c57ea1735d9e5ee0a4bTest
https://doi.org/10.1021/acs.jmedchem.2c01448Test

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دورية أكاديمية

Predictive classification models and targets identification for betulin derivatives as Leishmania donovani inhibitors

المؤلفون: Yuezhou Zhang, Henri Xhaard, Leo Ghemtio

المصدر: Journal of Cheminformatics, Vol 10, Iss 1, Pp 1-16 (2018)

مصطلحات موضوعية: Leishmania donovani inhibitors, Betulin derivatives, Predictive modeling, Classification models, Recursive partitioning, In silico target prediction, Information technology, T58.5-58.64, Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: http://link.springer.com/article/10.1186/s13321-018-0291-xTest; https://doaj.org/toc/1758-2946Test

الوصول الحر: https://doaj.org/article/21c7480e649348d38af3c4d5992e678fTest

View record in DOAJ

النص الكامل

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KNeMAP: A Network Mapping Approach for Knowledge-driven Comparison of Transcriptomic Profiles

المؤلفون: Alisa Pavel, Giusy del Giudice, Michele Fratello, Leo Ghemtio, Antonio Di Lieto, Jari Yli-Kauhaluoma, Henri Xhaard, Antonio Federico, Angela Serra, Dario Greco

المصدر: Bioinformatics.

مصطلحات موضوعية: Statistics and Probability, Computational Mathematics, Computational Theory and Mathematics, Molecular Biology, Biochemistry, Computer Science Applications

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::78e758eccb32b7f11fd45cab00f1b34eTest
https://doi.org/10.1093/bioinformatics/btad341Test

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دورية أكاديمية

Characterization of Ionizable Groups’ Environments in Proteins and Protein–Ligand Complexes through a Statistical Analysis of the Protein Data Bank

المؤلفون: Alexandre Borrel, Anne-Claude Camproux, Henri Xhaard

المصدر: ACS Omega, Vol 2, Iss 10, Pp 7359-7374 (2017)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2470-1343Test

الوصول الحر: https://doaj.org/article/aaffd7c449d74ddaa17b59908c42a3f1Test

View record in DOAJ

النص الكامل

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Exploring cooperative molecular contacts using a PostgreSQL database system

المؤلفون: Mael A. Briand, Loïc Dreano, Ashenafi Legehar, Evgeni Grazhdankin, Léo Ghemtio, Henri Xhaard

المصدر: Molecular Informatics. 42

مصطلحات موضوعية: Structural Biology, Organic Chemistry, Drug Discovery, Molecular Medicine, Computer Science Applications

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e83ebcea8bd8f71e5f0d07c29cee33c8Test
https://doi.org/10.1002/minf.202200235Test

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Exploration of Pyrazolo[1,5‐ a ]pyrimidines as Membrane‐Bound Pyrophosphatase Inhibitors

المؤلفون: Jianing Liu, Loic Dreano, Keni Vidilaseris, Gustav Boije af Gennäs, Jari Yli-Kauhaluoma, Arthur Lasbleiz, Henri Xhaard, Niklas G. Johansson, Alexandros Kiriazis, Orquidea Marilia de Castro Ribeiro, Adrian Goldman, Ayman Khattab, Seppo Meri

المساهمون: Division of Pharmacology and Pharmacotherapy, Divisions of Faculty of Pharmacy, Pharmaceutical Design and Discovery group, Division of Pharmaceutical Chemistry and Technology, Molecular and Integrative Biosciences Research Programme, Immunobiology Research Program, Drug Research Program, HUSLAB, Seppo Meri / Principal Investigator, Department of Bacteriology and Immunology, Biochemistry and Biotechnology, Jari Yli-Kauhaluoma / Principal Investigator, Computational Adme, Henri Xhaard / Principal Investigator, Division of Pharmaceutical Biosciences

المصدر: Chemmedchem

مصطلحات موضوعية: Pyrimidine, ANTIMALARIAL, Biochemistry, Pyrophosphate, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, parasitic diseases, Drug Discovery, Humans, ACIDOCALCISOMES, pyrazolo[1, Pyrophosphatases, 5-a]pyrimidine, General Pharmacology, Toxicology and Pharmaceutics, 030304 developmental biology, Pharmacology, 0303 health sciences, Pyrophosphatase, Inorganic pyrophosphatase, Dose-Response Relationship, Drug, Molecular Structure, Full Paper, PLASMODIUM-FALCIPARUM, biology, 030306 microbiology, Drug discovery, Organic Chemistry, LOCALIZATION, Plasmodium falciparum, Full Papers, biology.organism_classification, 3. Good health, inhibitor, Pyrimidines, TARGET, Membrane, chemistry, 317 Pharmacy, Thermotoga maritima, Pyrazoles, Molecular Medicine, H+-PPASE, pyrazolo[1,5-a]pyrimidine, membrane-bound pyrophosphatase, antiprotozoal agents, INORGANIC PYROPHOSPHATASE

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e278a2a6f27c85d051eefc4ff4c9fadTest
https://doi.org/10.1002/cmdc.202100392Test

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