المؤلفون: Schröder, Martin, Renatus, Martin, Liang, Xiaoyou, Meili, Fabian, Zoller, Thomas, Ferrand, Sandrine, Gauter, Francois, Li, Xiaoyan, Sigoillot, Frederic, Gleim, Scott, Stachyra, Therese-Marie, Thomas, Jason R., Begue, Damien, Khoshouei, Maryam, Lefeuvre, Peggy, Andraos-Rey, Rita, Chung, BoYee, Ma, Renate, Pinch, Benika, Hofmann, Andreas, Schirle, Markus, Schmiedeberg, Niko, Imbach, Patricia, Gorses, Delphine, Calkins, Keith, Bauer-Probst, Beatrice, Maschlej, Magdalena, Niederst, Matt, Maher, Rob, Henault, Martin, Alford, John, Ahrne, Erik, Tordella, Luca, Hollingworth, Greg, Thomä, Nicolas H., Vulpetti, Anna, Radimerski, Thomas, Holzer, Philipp, Carbonneau, Seth, Thoma, Claudio R.

المساهمون: EC | Horizon 2020 Framework Programme, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Verein fur Krebsforschung

المصدر: Nature Communications ; volume 15, issue 1 ; ISSN 2041-1723

مصطلحات موضوعية: General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Multidisciplinary

الإتاحة: https://doi.org/10.1038/s41467-023-44237-4Test
https://www.nature.com/articles/s41467-023-44237-4.pdfTest
https://www.nature.com/articles/s41467-023-44237-4Test

المؤلفون: Thomas, Jason R., Shelton, Claude, Murphy, Jason, Brittain, Scott, Bray, Mark-Anthony, Aspesi, Peter, Concannon, John, King, Frederick J., Ihry, Robert J., Ho, Daniel J., Henault, Martin, Hadjikyriacou, Andrea, Neri, Marilisa, Sigoillot, Frederic D., Pham, Helen T., Shum, Matthew, Barys, Louise, Jones, Michael D., Martin, Eric J., Blechschmidt, Anke, Rieffel, Sébastien, Troxler, Thomas J., Mapa, Felipa A., Jenkins, Jeremy L., Jain, Rishi K., Kutchukian, Peter S., Schirle, Markus, Renner, Steffen

المصدر: ACS Chemical Biology ; volume 19, issue 4, page 938-952 ; ISSN 1554-8929 1554-8937

الإتاحة: https://doi.org/10.1021/acschembio.3c00737Test

المؤلفون: Li, Jie, Canham, Stephen M., Wu, Hua, Henault, Martin, Chen, Lihao, Liu, Guoxun, Chen, Yu, Yu, Gary, Miller, Howard R., Hornak, Viktor, Brittain, Scott M., Michaud, Gregory A., Tutter, Antonin, Broom, Wendy, Digan, Mary Ellen, McWhirter, Sarah M., Sivick, Kelsey E., Pham, Helen T., Chen, Christine H., Tria, George S., McKenna, Jeffery M., Schirle, Markus, Mao, Xiaohong, Nicholson, Thomas B., Wang, Yuan, Jenkins, Jeremy L., Jain, Rishi K., Tallarico, John A., Patel, Sejal J., Zheng, Lianxing, Ross, Nathan T., Cho, Charles Y., Zhang, Xuewu, Bai, Xiao-Chen, Feng, Yan

المساهمون: U.S. Department of Health & Human Services | NIH | National Cancer Institute, Welch Foundation, Cancer Prevention and Research Institute of Texas

المصدر: Nature Chemical Biology ; ISSN 1552-4450 1552-4469

مصطلحات موضوعية: Cell Biology, Molecular Biology

الإتاحة: https://doi.org/10.1038/s41589-023-01434-yTest
https://www.nature.com/articles/s41589-023-01434-y.pdfTest
https://www.nature.com/articles/s41589-023-01434-yTest

المؤلفون: Schroeder, Martin, Liang, Xiaoyou, Meili, Fabian, Zoller, Thomas, Ferrand, Sandrine, Gauter, Francois, Li, Xiaoyan, Sigoillot, Frederic, Gleim, Scott, Stachyra, Therese-Marie, Thomas, Jason, Begue, Damien, Khoshouei, Maryam, Lefeuvre, Peggy, Andraos-Rey, Rita, Chung, BoYee, Pinch, Benika, Hofmann, Andreas, Schirle, Markus, Schmiedeberg, Niko, Gorses, Delphine, Calkins, Keith, Bauer-Probst, Beatrice, Maschlej, Magdalena, Niederst, Matt, Maher, Rob, Henault, Martin, Alford, John, Ahrne, Erik, Tordella, Luca, Hollingworth, Greg, Vulpetti, Anna, Holzer, Philipp, Carbonneau, Seth

العلاقة: Schroeder, Martin, Liang, Xiaoyou, Meili, Fabian, Zoller, Thomas, Ferrand, Sandrine, Gauter, Francois, Li, Xiaoyan, Sigoillot, Frederic, Gleim, Scott, Stachyra, Therese-Marie, Thomas, Jason, Begue, Damien, Khoshouei, Maryam, Lefeuvre, Peggy, Andraos-Rey, Rita, Chung, BoYee, Pinch, Benika, Hofmann, Andreas, Schirle, Markus, Schmiedeberg, Niko, Gorses, Delphine, Calkins, Keith, Bauer-Probst, Beatrice, Maschlej, Magdalena, Niederst, Matt, Maher, Rob, Henault, Martin, Alford, John, Ahrne, Erik, Tordella, Luca, Hollingworth, Greg, Vulpetti, Anna, Holzer, Philipp and Carbonneau, Seth (2024) DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nature communications, 15 (1). p. 275. ISSN 2041-1723

الإتاحة: https://doi.org/10.1038/s41467-023-44237-4Test
https://oak.novartis.com/52155Test/
https://www.nature.com/articles/s41467-023-44237-4?nstoken=7SOY%2FFbMog3%2FTQb%2FKItK4%2FIOd8jf7hd5HlW8itDchbgHkThOMV%2F%2Bf9OfldJ1%2F3qChVip%2FNr7MfoapPc5PBnEyfOUTpAAqj7lYpcCZb2YU0hS3JfxaKXrMxmrKhllJFOkEbCjmR5471EKCEn67CNVBSQGTZBaAOW0DikLuX3h5ogc6ZYuKJkbxtd6h95zGJGVhhowx3oScUfluAcC4VwjKbD0Tfc2%2BzB8Y0FKoVZLGHGzRSGU20ZJ3uDJ6xz0lnBxSq%2BpVxtQMC8qpW3anJr8K%2Bqg8%2BEYJfDuS4OrzPBJeyiwF72%2BuvACLKIwMFM%2F%2BcOboim228USjgKuMM2b3OYeaSBBucAg%2B9KQ8BUAI%2Bb7xWx4S9%2FYoy6AXSm4zafZau%2BClb%2FBTd8aSAD5QS6%2F7Pc5S0dpgdvNiJe9lxWjJ5UJ&nscheck=uiQdcCNKAFJM%2FvfgTjfo7w%3D%3DTest

المؤلفون: Li, Jingyao, Ho, Daniel J., Henault, Martin, Yang, Chian, Neri, Marilisa, Ge, Robin, Renner, Steffen, Mansur, Leandra, Lindeman, Alicia, Kelly, Brian, Tumkaya, Tayfun, Ke, Xiaoling, Soler-Llavina, Gilberto, Shanker, Gopi, Russ, Carsten, Hild, Marc, Gubser Keller, Caroline, Jenkins, Jeremy L., Worringer, Kathleen A., Sigoillot, Frederic D., Ihry, Robert J.

المصدر: ACS Chemical Biology ; volume 17, issue 6, page 1401-1414 ; ISSN 1554-8929 1554-8937

الإتاحة: https://doi.org/10.1021/acschembio.1c00920Test

المؤلفون: Li, Jie, Canham, Stephen M., Wu, Hua, Henault, Martin, Chen, Lihao, Liu, Guoxun, Chen, Yu, Yu, Gary, Miller, Howard R., Hornak, Viktor, Brittain, Scott M., Michaud, Gregory A., Tutter, Antonin, Broom, Wendy, Digan, Mary Ellen, McWhirter, Sarah M., Sivick, Kelsey E., Pham, Helen T., Chen, Christine H., Tria, George S., McKenna, Jeffery M., Schirle, Markus, Mao, Xiaohong, Nicholson, Thomas B., Wang, Yuan, Jenkins, Jeremy L., Jain, Rishi K., Tallarico, John A., Patel, Sejal J., Zheng, Lianxing, Ross, Nathan T., Cho, Charles Y., Zhang, Xuewu, Bai, Xiao-Chen, Feng, Yan

المصدر: Nature Chemical Biology; March 2024, Vol. 20 Issue: 3 p365-372, 8p

المؤلفون: Carbonneau, Seth, Sharma, Sujata, Peng, Liaomin, Rajan, Vaisakh, Hainzl, Dominik, Henault, Martin, Yang, Chian, Hale, Jacob, Shulok, Janine, Tallarico, John, Porter, Jeff, Brogdon, Jennifer L., Dranoff, Glenn, Bradner, James E., Hild, Marc, Guimaraes, Carla P.

المصدر: Cell Chemical Biology ; volume 28, issue 4, page 583 ; ISSN 2451-9456

مصطلحات موضوعية: Clinical Biochemistry, Drug Discovery, Pharmacology, Molecular Biology, Molecular Medicine, Biochemistry

الإتاحة: https://doi.org/10.1016/j.chembiol.2021.02.003Test
https://api.elsevier.com/content/article/PII:S2451945621000556?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2451945621000556?httpAccept=text/plainTest

المؤلفون: Ross, Nathan T., Lohmann, Felix, Carbonneau, Seth, Fazal, Aleem, Weihofen, Wilhelm A., Gleim, Scott, Salcius, Michael, Sigoillot, Frederic, Henault, Martin, Carl, Sarah H., Rodríguez-Molina, Juan B., Miller, Howard R., Brittain, Scott M., Murphy, Jason, Zambrowski, Mark, Boynton, Geoffrey, Wang, Yuan, Chen, Aye, Molind, Gregory J., Wilbertz, Johannes H., Artus-Revel, Caroline G., Jia, Min, Akinjiyan, Favour A., Turner, Jonathan, Knehr, Judith, Carbone, Walter, Schuierer, Sven, Reece-Hoyes, John S., Xie, Kevin, Saran, Chitra, Williams, Eric T., Roma, Guglielmo, Spencer, Matt, Jenkins, Jeremy, George, Elizabeth L., Thomas, Jason R., Michaud, Gregory, Schirle, Markus, Tallarico, John, Passmore, Lori A., Chao, Jeffrey A., Beckwith, Rohan E. J.

المساهمون: RCUK | Medical Research Council, Novartis Research Foundation, SNF-NCCR RNA & Disease network

المصدر: Nature Chemical Biology ; volume 16, issue 4, page 479-479 ; ISSN 1552-4450 1552-4469

مصطلحات موضوعية: Cell Biology, Molecular Biology

الإتاحة: https://doi.org/10.1038/s41589-020-0508-yTest
http://www.nature.com/articles/s41589-020-0508-y.pdfTest
http://www.nature.com/articles/s41589-020-0508-yTest

المؤلفون: Thomas, Jason R, Shelton IV, Claude, Murphy, Jason, Brittain, Scott, Bray, Mark-Anthony, Aspesi, Peter, Concannon, John, King, Frederick J, Ihry, Robert J, Ho, Daniel J, Henault, Martin, Hadjikyriacou, Andrea, Neri, Marilisa, Sigoillot, Frederic D, Pham, Helen T, Shum, Matthew, Barys, Louise, Jones, Michael D, Martin, Eric J, Blechschmidt, Anke, Rieffel, Sébastien, Troxler, Thomas J, Mapa, Felipa A, Jenkins, Jeremy L, Jain, Rishi K, Kutchukian, Peter S, Schirle, Markus, Renner, Steffen

الإتاحة: https://doi.org/10.26434/chemrxiv-2023-tlj9zTest
https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/64e85ef279853bbd78613583/original/new-insights-from-old-data-hunting-for-compounds-with-novel-mechanisms-using-cellular-high-throughput-screening-profiles-with-grey-chemical-matter.pdfTest

المؤلفون: Ye, Chaoyang, Ho, Daniel J., Neri, Marilisa, Yang, Chian, Kulkarni, Tripti, Randhawa, Ranjit, Henault, Martin, Mostacci, Nadezda, Farmer, Pierre, Renner, Steffen, Ihry, Robert, Mansur, Leandra, Keller, Caroline Gubser, McAllister, Gregory, Hild, Marc, Jenkins, Jeremy, Kaykas, Ajamete

المصدر: Nature Communications ; volume 9, issue 1 ; ISSN 2041-1723

مصطلحات موضوعية: General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Multidisciplinary

الإتاحة: https://doi.org/10.1038/s41467-018-06500-xTest
https://www.nature.com/articles/s41467-018-06500-x.pdfTest
https://www.nature.com/articles/s41467-018-06500-xTest