المؤلفون: Goepfert, Arnaud, Barske, Carmen, Lehmann, Sylvie, Wirth, Emmanuelle, Willemsen, Joschka, Gudjonsson, Johann E., Ward, Nicole L., Sarkar, Mrinal K., Hemmig, René, Kolbinger, Frank, Rondeau, Jean-Michel

المصدر: Cell Reports ; volume 41, issue 3, page 111489 ; ISSN 2211-1247

مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology

الإتاحة: https://doi.org/10.1016/j.celrep.2022.111489Test
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المؤلفون: Alper, Phil, Betschart, Claudia, André, Cédric, Boulay, Thomas, Cheng, Dai, Deane, Jonathan, Faller, Michael, Feifel, Roland, Glatthar, Ralf, Han, Dong, Hemmig, Rene, Jiang, Tao, Knoepfel, Thomas, Maginnis, Jillian, Mutnick, Daniel, Pei, Wei, Ruzzante, Giulia, Syka, Peter, Zhang, Guobao, Zhang, Yi

المصدر: ACS Medicinal Chemistry Letters; 8/10/2023, Vol. 14 Issue 8, p1054-1062, 9p

المؤلفون: Michellys, Pierre-Yves, Pei, Wei, Zhang, Yi, Jiang, Tao, Han, Dong, Zhang, Guobao, Chang, Dai, Alper, Phillip, Mutnick, Daniel, Deane, Jonathan, Syka, Peter, Maginnis, Jillian, Junt, Tobias, Knoepfel, Thomas, Betschart, Claudia, Glatthar, Ralf, Feifel, Roland, Faller, Michael, Hemmig, Rene, Zink, Florence

العلاقة: Michellys, Pierre-Yves, Pei, Wei, Zhang, Yi, Jiang, Tao, Han, Dong, Zhang, Guobao, Chang, Dai, Alper, Phillip, Mutnick, Daniel, Deane, Jonathan, Syka, Peter, Maginnis, Jillian, Junt, Tobias, Knoepfel, Thomas, Betschart, Claudia, Glatthar, Ralf, Feifel, Roland, Faller, Michael, Hemmig, Rene and Zink, Florence (2023) Discovery of the TLR7/8 Antagonist MHV370 for Treatment of Systemic Autoimmune Diseases. ACS medicinal chemistry letters, 14 (8). pp. 1054-1062. ISSN 1948-5875

الإتاحة: https://doi.org/10.1021/acsmedchemlett.3c00136Test
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المؤلفون: Betschart, Claudia, Faller, Michael, Zink, Florence, Hemmig, Rene, Blank, Jutta, Vangrevelinghe, Eric, Bourrel, Marjorie, Glatthar, Ralf, Behnke, Dirk, Barker, Kerstin, Heizmann, Andreas, Angst, Daniela, Nimsgern, Pierre, Jacquier, Sebastien, Junt, Tobias, Collignon Zipfel, Geraldine, Ruzzante, Giulia, Loetscher, Pius, Limonta, Sarah, Hawtin, Stuart, Andre, Cedric Bernard, Boulay, Thomas, Feifel, Roland, Knoepfel, Thomas

العلاقة: Betschart, Claudia, Faller, Michael, Zink, Florence, Hemmig, Rene, Blank, Jutta, Vangrevelinghe, Eric, Bourrel, Marjorie, Glatthar, Ralf, Behnke, Dirk, Barker, Kerstin, Heizmann, Andreas, Angst, Daniela, Nimsgern, Pierre, Jacquier, Sebastien, Junt, Tobias, Collignon Zipfel, Geraldine, Ruzzante, Giulia, Loetscher, Pius, Limonta, Sarah, Hawtin, Stuart, Andre, Cedric Bernard, Boulay, Thomas, Feifel, Roland and Knoepfel, Thomas (2022) Structure-based optimization of a fragment like TLR8 binding screening hit to an in vivo efficacious TLR7/8 antagonist. ACS Medicinal Chemistry Letters. ISSN 1948-58751948-5875

الإتاحة: https://doi.org/10.1021/acsmedchemlett.1c00696Test
https://oak.novartis.com/46530Test/

المؤلفون: Schutzius, Gabi, Hauer, Christian, Bergling, Sebastian, Tortelli, Federico, Fuchs, Florian, Renner, Steffen, Guagnano, Vito, Cotesta, Simona, Rueeger, Heinrich, Faller, Michael, Bouchez, Laure, Salathe, Adrian, Nigsch, Florian, Richards, Shola, Louis, Malvina Caroline, Gruber, Viktoria, Aebi, Alexandra, Turner, Jonathan, Grandjean, Frederic, Li, Jun, Dimitri, Christopher, Thomas, Jason, Schirle, Markus, Blank, Jutta, Drueckes, Peter, Vaupel, Andrea, Tiedt, Ralph, Manley, Paul, Klopp, Julia, Hemmig, Rene, Zink, Florence, Leroy, Nelly, Carbone, Walter, Roma, Guglielmo, Gubser Keller, Caroline, Dales, Natalie, Beyerbach, Armin, Zimmerlin, Alfred Gilbert, Bonenfant, Debora, Terranova, Remi, Berwick, Amy, Sahambi, Sukhdeep, Reynolds, Aimee, Jennings, Lori, Ruffner, Heinz, Tarsa, Peter, Bouwmeester, Antonius, Driver, Vickie, Frederiksen, Mathias, Lohmann, Felix, Kirkland, Susan

العلاقة: Schutzius, Gabi, Hauer, Christian, Bergling, Sebastian, Tortelli, Federico, Fuchs, Florian, Renner, Steffen, Guagnano, Vito, Cotesta, Simona, Rueeger, Heinrich, Faller, Michael, Bouchez, Laure, Salathe, Adrian, Nigsch, Florian, Richards, Shola, Louis, Malvina Caroline, Gruber, Viktoria, Aebi, Alexandra, Turner, Jonathan, Grandjean, Frederic, Li, Jun, Dimitri, Christopher, Thomas, Jason, Schirle, Markus, Blank, Jutta, Drueckes, Peter, Vaupel, Andrea, Tiedt, Ralph, Manley, Paul, Klopp, Julia, Hemmig, Rene, Zink, Florence, Leroy, Nelly, Carbone, Walter, Roma, Guglielmo, Gubser Keller, Caroline, Dales, Natalie, Beyerbach, Armin, Zimmerlin, Alfred Gilbert, Bonenfant, Debora, Terranova, Remi, Berwick, Amy, Sahambi, Sukhdeep, Reynolds, Aimee, Jennings, Lori, Ruffner, Heinz, Tarsa, Peter, Bouwmeester, Antonius, Driver, Vickie, Frederiksen, Mathias, Lohmann, Felix and Kirkland, Susan (2021) BET bromodomain inhibitors regulate keratinocyte plasticity. Nature Chemical Biology, 17 (3). pp. 280-290. ISSN 15524469

الإتاحة: https://doi.org/10.1038/s41589-020-00716-zTest
https://oak.novartis.com/38624Test/

المؤلفون: Thomson, Christopher G., Le Grand, Darren, Dowling, Mark, Beattie, David, Elphick, Lucy, Faller, Michael, Freeman, Mark, Hardaker, Elizabeth, Head, Victoria, Hemmig, Rene, Hill, Johan, Lister, Andrew, Pascoe, David, Rieffel, Sebastien, Shrestha, Binesh, Steward, Oliver, Zink, Florence

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 31, page 127663 ; ISSN 0960-894X

مصطلحات موضوعية: Organic Chemistry, Clinical Biochemistry, Drug Discovery, Pharmaceutical Science, Molecular Biology, Molecular Medicine, Biochemistry

الإتاحة: https://doi.org/10.1016/j.bmcl.2020.127663Test
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المؤلفون: Thomson, Christopher, Le Grand, Darren, Dowling, Mark, Beattie, David, Elphick, Lucy, Faller, Michael, Freeman, Mark, Hardaker, Elizabeth, Head, Victoria, Hemmig, Rene, Hill, Johan, Lister, Andrew, Pascoe, David, Rieffel, Sebastien, Shresta, Binesh, Steward, Oliver, Zink, Florence

العلاقة: Thomson, Christopher, Le Grand, Darren, Dowling, Mark, Beattie, David, Elphick, Lucy, Faller, Michael, Freeman, Mark, Hardaker, Elizabeth, Head, Victoria, Hemmig, Rene, Hill, Johan, Lister, Andrew, Pascoe, David, Rieffel, Sebastien, Shresta, Binesh, Steward, Oliver and Zink, Florence (2020) Development of autotaxin inhibitors: A series of tetrazole cinnamides. Bioorganic and medicinal chemistry letters. ISSN 0960894X

الإتاحة: https://doi.org/10.1016/j.bmcl.2020.127663Test
https://oak.novartis.com/41765Test/

المؤلفون: Rondeau, Jean‐Michel, Bitsch, Francis, Bourgier, Emmanuelle, Geiser, Martin, Hemmig, Rene, Kroemer, Markus, Lehmann, Sylvie, Ramage, Paul, Rieffel, Sebastien, Strauss, André, Green, Jonathan R., Jahnke, Wolfgang

المصدر: ChemMedChem ; volume 1, issue 2, page 165-165 ; ISSN 1860-7179 1860-7187

الإتاحة: https://doi.org/10.1002/cmdc.200690003Test

المؤلفون: Cheneval, Dominique, Ramage, Paul, Kastelic, Tania, Szelestenyi, Terez, Niggli, Heinz, Hemmig, René, Bachmann, Martin, MacKenzie, Andrew

المصدر: Journal of Biological Chemistry ; volume 273, issue 28, page 17846-17851 ; ISSN 0021-9258

مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry

الإتاحة: https://doi.org/10.1074/jbc.273.28.17846Test
https://api.elsevier.com/content/article/PII:S0021925818805646?httpAccept=text/xmlTest
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المؤلفون: Ramage, Paul, Cheneval, Dominique, Chvei, Maria, Graff, Patrick, Hemmig, Rene, Heng, Richard, Kocher, Hans Peter, Mackenzie, Andrew, Memmert, Klaus, Revesz, Laszlo, Wishart, William

المصدر: Journal of Biological Chemistry ; volume 270, issue 16, page 9378-9383 ; ISSN 0021-9258

مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry

الإتاحة: https://doi.org/10.1074/jbc.270.16.9378Test
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