المؤلفون: Skinder, Natalia, Sanz Fernández, Irene, Dethmers-Ausema, Albertina, Weersing, Ellen, de Haan, Gerald

المصدر: Skinder , N , Sanz Fernández , I , Dethmers-Ausema , A , Weersing , E & de Haan , G 2024 , ' CD61 identifies a superior population of aged murine HSCs and is required to preserve quiescence and self-renewal ' , Blood Advances , vol. 8 , no. 1 , pp. 99-111 . https://doi.org/10.1182/bloodadvances.2023011585Test

مصطلحات موضوعية: Animals, Mice, Aging, Bone Marrow, Hematopoietic Stem Cells/metabolism, Integrin beta3/metabolism

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/e9f7d0e1-d4a4-411a-8509-bc70b6cbc2b8Test

الإتاحة: https://doi.org/10.1182/bloodadvances.2023011585Test
https://hdl.handle.net/11370/e9f7d0e1-d4a4-411a-8509-bc70b6cbc2b8Test
https://research.rug.nl/en/publications/e9f7d0e1-d4a4-411a-8509-bc70b6cbc2b8Test
https://pure.rug.nl/ws/files/884396807/blooda_adv-2023-011585-main.pdfTest

المؤلفون: Buoninfante, Olimpia Alessandra, Pilzecker, Bas, Spanjaard, Aldo, de Groot, Daniël, Prekovic, Stefan, Song, Ji-Ying, Lieftink, Cor, Ayidah, Matilda, Pritchard, Colin E J, Vivié, Judith, Mcgrath, Kathleen E, Huijbers, Ivo J, Philipsen, Sjaak, von Lindern, Marieke, Zwart, Wilbert, Beijersbergen, Roderick L, Palis, James, van den Berk, Paul C M, Jacobs, Heinz

المساهمون: Cancer, CMM Groep Van Mil

مصطلحات موضوعية: Animals, DDT, DNA Damage, DNA Repair, DNA Replication, Hematopoietic Stem Cells/metabolism, Mammals/metabolism, Proliferating Cell Nuclear Antigen/metabolism, Ubiquitination, DNA damage tolerance (DDT), DNA damage response (DDR), embryonic lethality, erythropoiesis, hematopoietic stem cells, General, Journal Article

وصف الملف: application/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/449106Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/449106Test

المؤلفون: Stacey, Simon N., Zink, Florian, Halldórsson, Gísli Hreinn, Stefánsdóttir, Lilja, Guðjónsson, Sigurjón Axel, Einarsson, Gudmundur, Hjörleifsson, Grimur, Eiríksdóttir, Þjóðbjörg, Helgadottir, Anna, Björnsdottir, Gyda, Thorgeirsson, Thorgeir E., Ólafsdóttir, Þórunn Ásta, Jónsdóttir, Ingileif, Gretarsdottir, Solveig, Tragante, Vinicius, Magnússon, Magnús Karl, Jonsson, Hakon, Gudmundsson, Julius, Olafsson, Sigurgeir, Holm, Hilma, Gudbjartsson, Daniel F., Sulem, Patrick, Helgason, Agnar Sturla, Þorsteinsdóttir, Unnur, Tryggvadottir, Laufey, Rafnar, Thorunn, Melsted, Páll, Úlfarsson, Magnús Örn, Viðarsson, Brynjar, Thorleifsson, Gudmar, Stefánsson, Kári

المساهمون: Faculty of Industrial Engineering, Mechanical Engineering and Computer Science, Faculty of Medicine, Faculty of Sociology, Anthropology and Folkloristics, Faculty of Electrical and Computer Engineering, Health Sciences, Landspitali - The National University Hospital of Iceland

مصطلحات موضوعية: Náttúrufræðingar, Blóðlæknisfræði, Humans, Aged, Clonal Hematopoiesis/genetics, Genome-Wide Association Study, Hematopoiesis/genetics, Mutation/genetics, Hematopoietic Stem Cells/metabolism, Genetics

وصف الملف: 2149-2159

العلاقة: Nature Genetics; 55(12); http://www.scopus.com/inward/record.url?scp=85175838978&partnerID=8YFLogxKTest; Stacey , S N , Zink , F , Halldórsson , G H , Stefánsdóttir , L , Guðjónsson , S A , Einarsson , G , Hjörleifsson , G , Eiríksdóttir , Þ , Helgadottir , A , Björnsdottir , G , Thorgeirsson , T E , Ólafsdóttir , Þ Á , Jónsdóttir , I , Gretarsdottir , S , Tragante , V , Magnússon , M K , Jonsson , H , Gudmundsson , J , Olafsson , S , Holm , H , Gudbjartsson , D F , Sulem , P , Helgason , A S , Þorsteinsdóttir , U , Tryggvadottir , L , Rafnar , T , Melsted , P , Úlfarsson , M Ö , Viðarsson , B , Thorleifsson , G & Stefánsson , K 2023 , ' Genetics and epidemiology of mutational barcode-defined clonal hematopoiesis ' , Nature Genetics , vol. 55 , no. 12 , pp. 2149-2159 . https://doi.org/10.1038/s41588-023-01555-zTest; 212173543; c65bb732-b036-4b90-9c21-eb975cb3e579; 85175838978; https://hdl.handle.net/20.500.11815/4551Test

الإتاحة: https://doi.org/20.500.11815/4551Test
https://doi.org/10.1038/s41588-023-01555-zTest
https://hdl.handle.net/20.500.11815/4551Test

المؤلفون: Naveh, Claire A, Roberts, Kiran, Zakrzewski, Przemysław, Rice, Christopher M, Ponce-Garcia, Fernando M, Fleming, Kathryn, Thompson, Megan, Panyapiean, Nawamin, Jiang, Huan, Diezmann, Stephanie, Moura, Pedro L, Toye, Ashley M, Amulic, Borko

المصدر: Naveh , C A , Roberts , K , Zakrzewski , P , Rice , C M , Ponce-Garcia , F M , Fleming , K , Thompson , M , Panyapiean , N , Jiang , H , Diezmann , S , Moura , P L , Toye , A M & Amulic , B 2024 , ' Neutrophils cultured ex vivo from CD34+ stem cells are immature and genetically tractable ' , Journal of Translational Medicine , vol. 22 , no. 1 , 526 , pp. 526 . https://doi.org/10.1186/s12967-024-05337-xTest

مصطلحات موضوعية: Humans, Neutrophils/metabolism, Antigens, CD34/metabolism, Cells, Cultured, Reactive Oxygen Species/metabolism, Proteomics, Hematopoietic Stem Cells/metabolism, Gene Editing, Cell Degranulation, Stem Cells/metabolism, Cytokines/metabolism, Phenotype

العلاقة: https://research-information.bris.ac.uk/en/publications/e8c6d781-7140-4b1f-9639-7183c17b8d6aTest

الإتاحة: https://doi.org/10.1186/s12967-024-05337-xTest
https://hdl.handle.net/1983/e8c6d781-7140-4b1f-9639-7183c17b8d6aTest
https://research-information.bris.ac.uk/en/publications/e8c6d781-7140-4b1f-9639-7183c17b8d6aTest

المؤلفون: Thambyrajah, Roshana, Maqueda, Maria, Neo, Wen Hao, Imbach, Kathleen, Guillén, Yolanda, Grases, Daniela, Fadlullah, Zaki, Gambera, Stefano, Matteini, Francesca, Wang, Xiaonan, Calero-Nieto, Fernando J, Esteller, Manel, Florian, Maria Carolina, Porta, Eduard, Benedito, Rui, Göttgens, Berthold, Lacaud, Georges, Espinosa, Lluis, Bigas, Anna

المصدر: Thambyrajah , R , Maqueda , M , Neo , W H , Imbach , K , Guillén , Y , Grases , D , Fadlullah , Z , Gambera , S , Matteini , F , Wang , X , Calero-Nieto , F J , Esteller , M , Florian , M C , Porta , E , Benedito , R , Göttgens , B , Lacaud , G , Espinosa , L & Bigas , A 2024 , ' Cis inhibition of NOTCH1 through JAGGED1 sustains embryonic hematopoietic stem cell fate ' , Nature Communications , vol. ....

مصطلحات موضوعية: Receptor, Notch1/genetics, Hematopoietic Stem Cells/metabolism, Cell Differentiation/genetics, Aorta/metabolism, Arteries/metabolism, Mesonephros, Gonads/metabolism

العلاقة: https://research.manchester.ac.uk/en/publications/12952f6e-d73d-411e-afbe-402c4d9b0b52Test

الإتاحة: https://doi.org/10.1038/s41467-024-45716-yTest
https://research.manchester.ac.uk/en/publications/12952f6e-d73d-411e-afbe-402c4d9b0b52Test

المؤلفون: Fang, Z., Corbizi Fattori, G., McKerrell, T., Boucher, R. H., Jackson, A., Fletcher, R. S., Forte, D., Martin, J. E., Fox, S., Roberts, J., Glover, R., Harris, E., Bridges, H. R., Grassi, L., Rodriguez-Meira, A., Mead, A. J., Knapper, S., Ewing, J., Butt, N. M., Jain, M., Francis, S., Clark, F. J., Coppell, J., McMullin, M. F., Wadelin, F., Narayanan, S., Milojkovic, D., Drummond, M. W., Sekhar, M., ElDaly, H., Hirst, J., Paramor, M., Baxter, E. J., Godfrey, A. L., Harrison, C. N., Méndez-Ferrer, S.

مصطلحات موضوعية: Humans, Myeloproliferative Disorders/drug therapy/genetics/pathology, Janus Kinase 2/genetics/metabolism, Hematopoietic Stem Cells/metabolism, Signal Transduction, Neoplasms/metabolism, Tamoxifen/therapeutic use/metabolism, Mutation, Calreticulin/genetics/metabolism

العلاقة: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/38001082Test/; Fang Z, Corbizi Fattori G, McKerrell T, Boucher RH, Jackson A, Fletcher RS, et al. Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis. Nature communications. 2023;14(1):7725.; Nature communications; PMC10673935 Janssen, CTI, Celgene, and Medscape; and advisory board membership for Incyte, CTI, Sierra Oncology, Novartis, Celgene, Roche, AOP pharma, Geron, and AstraZeneca. A.J.M. reports funded research from Novartis, Celgene/BMS and consultancy for Abbvie, CTI, and Gilead. S.K. reports funded research and advisory board membership for Novartis. J.E. reports advisory board membership for Novartis, Incyte and Celgene/BMS. M.F.M. reports consultancies for Celgene and BMS; and advisory board membership for Novartis, Jazz, and Abbvie. S.N. reports speaker fees for Takeda, Celgene, Novartis, MSD and Alexion. D.M. reports consultancy for Incyte, Pfizer, Novartis, and Bristol-Myers Squibb. M.W.D. reports funded research from Blueprint Medicine Corporation and advisory board membership for Bristol-Myers Squibb, Novartis, Gilead, Pfizer, Jazz, Takeda, and Astellas. The remaining authors declare no competing financial interests. A.L.G. reports speaker fees from Novartis and advisory board membership AOP pharma and BMS.; https://hdl.handle.net/11287/623100Test

الإتاحة: https://doi.org/10.1038/s41467-023-43175-5Test
https://hdl.handle.net/11287/623100Test

المؤلفون: Poisa-Beiro, Laura, Landry, Jonathan J M, Raffel, Simon, Tanaka, Motomu, Zaugg, Judith, Gavin Perrin, Anne-Claude, Ho, Anthony D

المصدر: ISSN: 1422-0067 ; International journal of molecular sciences, vol. 23, no. 6 (2022) 3028.

مصطلحات موضوعية: info:eu-repo/classification/ddc/612, Aging, Central carbon metabolism, Glycolysis, Hematopoietic stem and progenitor cells, Senescence signature, Aging / genetics, Animals, Biomarkers / metabolism, Cell Differentiation, Glucose / metabolism, Hematopoietic Stem Cells / metabolism, Mice

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35328449; https://archive-ouverte.unige.ch/unige:160625Test; unige:160625

الإتاحة: https://doi.org/10.3390/ijms23063028Test
https://archive-ouverte.unige.ch/unige:160625Test

المؤلفون: Solman, Maja, Blokzijl-Franke, Sasja, Piques, Florian, Yan, Chuan, Yang, Qiqi, Strullu, Marion, Kamel, Sarah M, Ak, Pakize, Bakkers, Jeroen, Langenau, David M, Cavé, Hélène, den Hertog, Jeroen

المصدر: Solman , M , Blokzijl-Franke , S , Piques , F , Yan , C , Yang , Q , Strullu , M , Kamel , S M , Ak , P , Bakkers , J , Langenau , D M , Cavé , H & den Hertog , J 2022 , ' Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects ' , eLife , vol. 11 . https://doi.org/10.7554/eLife.73040Test

مصطلحات موضوعية: Animals, Hematopoietic Stem Cells/metabolism, Humans, Leukemia, Myelomonocytic, Juvenile/genetics, Mutation, Noonan Syndrome/genetics, Protein Tyrosine Phosphatase, Non-Receptor Type 11/genetics, Zebrafish

العلاقة: https://pure.knaw.nl/portal/en/publications/49ac1364-f68c-4d6e-8a97-fd371a0c2425Test

الإتاحة: https://doi.org/10.7554/eLife.73040Test
https://doi.org/20.500.11755/49ac1364-f68c-4d6e-8a97-fd371a0c2425Test
https://pure.knaw.nl/portal/en/publications/49ac1364-f68c-4d6e-8a97-fd371a0c2425Test
https://hdl.handle.net/20.500.11755/49ac1364-f68c-4d6e-8a97-fd371a0c2425Test

المؤلفون: Klaus, Anna, Clapes, Thomas, Yvernogeau, Laurent, Basu, Sreya, Weijts, Bart, Maas, Joris, Smal, Ihor, Galjart, Niels, Robin, Catherine

المصدر: Klaus , A , Clapes , T , Yvernogeau , L , Basu , S , Weijts , B , Maas , J , Smal , I , Galjart , N & Robin , C 2022 , ' CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development ' , Cell Reports , vol. 39 , no. 11 , pp. 110957 . https://doi.org/10.1016/j.celrep.2022.110957Test

مصطلحات موضوعية: Animals, Hematopoiesis/genetics, Hematopoietic Stem Cells/metabolism, Mice, Microtubule-Associated Proteins/metabolism, Proto-Oncogene Proteins c-kit/metabolism, Receptor Protein-Tyrosine Kinases/metabolism, Zebrafish

الإتاحة: https://doi.org/10.1016/j.celrep.2022.110957Test
https://doi.org/20.500.11755/d9d459f4-954e-4dd2-a1f2-100cf9951faaTest
https://pure.knaw.nl/portal/en/publications/d9d459f4-954e-4dd2-a1f2-100cf9951faaTest
https://hdl.handle.net/20.500.11755/d9d459f4-954e-4dd2-a1f2-100cf9951faaTest

المؤلفون: Wobus, Manja, Mies, Anna, Asokan, Nandini, Oelschlägel, Uta, Möbus, Kristin, Winter, Susann, Cross, Michael, Weidner, Heike, Rauner, Martina, Hofbauer, Lorenz C., Bornhäuser, Martin, Platzbecker, Uwe

المصدر: http://lobid.org/resources/99370672770606441Test#!, 35(10):2936-2947.

مصطلحات موضوعية: Hematopoietic Stem Cells/metabolism [MeSH], Immunoglobulin Fc Fragments/pharmacology [MeSH], Smad2 Protein/genetics [MeSH], Hematopoiesis [MeSH], Aged [MeSH], Mesenchymal Stem Cells/drug effects [MeSH], Translational research, Stem-cell research, Tumor Cells, Cultured [MeSH], Haematopoietic stem cells, Zebrafish [MeSH], Myelodysplastic Syndromes/drug therapy [MeSH], Activin Receptors, Type II/pharmacology [MeSH], Case-Control Studies [MeSH], Hematinics/pharmacology [MeSH], Chemokine CXCL12/metabolism [MeSH], Myelodysplastic Syndromes/pathology [MeSH], Recombinant Fusion Proteins/pharmacology [MeSH], Mesenchymal Stem Cells/pathology [MeSH], Adult [MeSH], Humans [MeSH], Chemokine CXCL12/genetics [MeSH], Middle Aged [MeSH], Animals [MeSH], Smad2 Protein/metabolism [MeSH], Hematopoietic Stem Cells/drug effects [MeSH], Myelodysplastic Syndromes/metabolism [MeSH], Mesenchymal Stem Cells/metabolism [MeSH]

العلاقة: https://repository.publisso.de/resource/frl:6443820Test; https://doi.org/10.1038/s41375-021-01275-5Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478655Test/

الإتاحة: https://doi.org/10.1038/s41375-021-01275-5Test
https://repository.publisso.de/resource/frl:6443820Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478655Test/