المؤلفون: Niko Hensel, Svetlana Baskal, Lisa Marie Walter, Hella Brinkmann, Manuela Gernert, Peter Claus

المصدر: Neurobiology of Disease, Vol 108, Iss , Pp 352-361 (2017)

مصطلحات موضوعية: Spinal Muscular Atrophy, Motoneuron disease, Signaling, Rho kinase, ERK, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S0969996117302152Test; https://doaj.org/toc/1095-953XTest

الوصول الحر: https://doaj.org/article/5753b7c189d14319b5f806d2343fe651Test

المؤلفون: Sebastian Rademacher, Nora T. Detering, Tobias Schüning, Robert Lindner, Pamela Santonicola, Inga-Maria Wefel, Janina Dehus, Lisa M. Walter, Hella Brinkmann, Agathe Niewienda, Katharina Janek, Miguel A. Varela, Melissa Bowerman, Elia Di Schiavi, Peter Claus

المصدر: Cells, Vol 9, Iss 11, p 2405 (2020)

مصطلحات موضوعية: mass spectrometry, phosphorylation, PTEN, SMN, spinal muscular atrophy, Cytology, QH573-671

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/2073-4409/9/11/2405Test; https://doaj.org/toc/2073-4409Test

الوصول الحر: https://doaj.org/article/7097473dd94a440e803af1b7c34e2a24Test

المؤلفون: Benjamin Förthmann, Jeroen van Bergeijk, Yu-Wei Lee, Verena Lübben, Yvonne Schill, Hella Brinkmann, Andreas Ratzka, Michal K Stachowiak, Michael Hebert, Claudia Grothe, Peter Claus

المصدر: PLoS ONE, Vol 8, Iss 12, p e82871 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: http://europepmc.org/articles/PMC3866168?pdf=renderTest; https://doaj.org/toc/1932-6203Test

الوصول الحر: https://doaj.org/article/ff076f29399142cb86fa9a882184af86Test

المؤلفون: Niko Hensel, Andreas Ratzka, Hella Brinkmann, Lars Klimaschewski, Claudia Grothe, Peter Claus

المصدر: PLoS ONE, Vol 7, Iss 2, p e31202 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: http://europepmc.org/articles/PMC3278439?pdf=renderTest; https://doaj.org/toc/1932-6203Test

الوصول الحر: https://doaj.org/article/9cb7fde236e0447e83c381a4b12515edTest

المؤلفون: Manuela F. Richter, Stefania Corti, Pamela Santonicola, Michela Taiana, Silke Fischer, Tobias Schüning, Natascha Heidrich, Elisa Pagliari, Sabrina Kubinski, Elia Di Schiavi, Klaus Jung, Peter Claus, Antonia Joseph, Anke K. Bergmann, Federica Cieri, Hella Brinkmann, Ines Tapken, Niko Hensel

المصدر: Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America (Online) (2021). doi:10.1073/pnas.2007785118
info:cnr-pdr/source/autori:Hensel N, Cieri F, Santonicola P, Tapken I, Schüning T, Taiana M, Pagliari E, Joseph A, Fischer S, Heidrich N, Brinkmann H, Kubinski S, Bergmann AK, Richter MF, Jung K, Corti S, Di Schiavi E, Claus P./titolo:Impairment of the neurotrophic signaling hub B-Raf contributes to motoneuron degeneration in spinal muscular atrophy/doi:10.1073%2Fpnas.2007785118/rivista:Proceedings of the National Academy of Sciences of the United States of America (Online)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume

مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, MAPK/ERK pathway, SMN1, Biology, Muscular Atrophy, Spinal, Mice, medicine, Animals, Humans, SMA, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Protein kinase B, 14-3-3, spinal muscular atrophy, Motor Neurons, Multidisciplinary, Raf, Spinal muscular atrophy, Biological Sciences, Fibroblasts, medicine.disease, biology.organism_classification, Survival of Motor Neuron 1 Protein, neurotrophic signaling, Cell biology, Disease Models, Animal, 14-3-3 Proteins, Gene Expression Regulation, Spinal Cord, nervous system, Nerve Degeneration, biology.protein, raf Kinases, Signal transduction, Signal Transduction, Neurotrophin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b651af1752779ced779f4a1559a729dTest
https://doi.org/10.1073/pnas.2007785118Test

المؤلفون: Katja Borns, Frauke von Versen-Höynck, Bianca Schröder-Heurich, Peter Claus, Constantin von Kaisenberg, Lars Brodowski, Berina Kipke, Hella Brinkmann, Sandra von Hardenberg, Nadia Meyer

المصدر: The FASEB Journal. 33:9142-9153

مصطلحات موضوعية: 0301 basic medicine, Angiogenesis, Cell, Inflammation, Biochemistry, Capillary Permeability, Colony-Forming Units Assay, 03 medical and health sciences, 0302 clinical medicine, Antigens, CD, Cell Movement, Cell Adhesion, Human Umbilical Vein Endothelial Cells, Genetics, medicine, Vitamin D and neurology, Humans, Vitamin D, Endothelial dysfunction, Progenitor cell, Molecular Biology, Cells, Cultured, Endothelial Progenitor Cells, Tumor Necrosis Factor-alpha, Chemistry, Adherens Junctions, Cofilin, Cadherins, medicine.disease, Coculture Techniques, Cell biology, 030104 developmental biology, medicine.anatomical_structure, medicine.symptom, VE-cadherin, 030217 neurology & neurosurgery, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c3897397583ebae43849cd6275d536Test
https://doi.org/10.1096/fj.201802750rrTest

المؤلفون: Lisa Marie Walter, Miguel A. Varela, Peter Claus, Sebastian Rademacher, Pamela Santonicola, Katharina Janek, Melissa Bowerman, Hella Brinkmann, Inga-Maria Wefel, Janina Dehus, Agathe Niewienda, Robert Lindner, Tobias Schüning, Elia Di Schiavi, Nora Tula Detering

المصدر: Cells, Vol 9, Iss 2405, p 2405 (2020)
Cells
Volume 9
Issue 11
Cells 9 (2020). doi:10.3390/cells9112405
info:cnr-pdr/source/autori:Rademacher, Sebastian; Detering, Nora T.; Schüning, Tobias; Lindner, Robert; Santonicola, Pamela; Wefel, Inga Maria; Dehus, Janina; Walter, Lisa M.; Brinkmann, Hella; Niewienda, Agathe; Janek, Katharina; Varela, Miguel A.; Bowerman, Melissa; Di Schiavi, Elia; Claus, Peter/titolo:A Single Amino Acid Residue Regulates PTEN-Binding and Stability of the Spinal Muscular Atrophy Protein SMN/doi:10.3390%2Fcells9112405/rivista:Cells/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:9

مصطلحات موضوعية: 0301 basic medicine, PTEN, animal diseases, Q1, Mice, Phosphoserine, 0302 clinical medicine, Tensin, Amino Acids, lcsh:QH301-705.5, mass spectrometry, spinal muscular atrophy, biology, Protein Stability, Chemistry, Kinase, phosphorylation, General Medicine, RC346, SMA, Cell biology, SMN, Gene Knockdown Techniques, Phosphorylation, Protein Binding, Proteasome Endopeptidase Complex, Phosphatase, Article, Structure-Activity Relationship, 03 medical and health sciences, Cell Line, Tumor, medicine, Animals, Humans, Amino Acid Sequence, Caenorhabditis elegans, Cell Nucleus, PTEN Phosphohydrolase, Spinal muscular atrophy, medicine.disease, Survival of Motor Neuron 1 Protein, R1, nervous system diseases, 030104 developmental biology, nervous system, lcsh:Biology (General), Proteolysis, biology.protein, Mutant Proteins, RA, 030217 neurology & neurosurgery, Nuclear localization sequence

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fe3b02a1b2aafd2063c58a772faba5Test
https://www.mdpi.com/2073-4409/9/11/2405Test

المؤلفون: Peter Claus, Niko Hensel, Hella Brinkmann, Manuela Gernert, Svetlana Baskal, Lisa Marie Walter

المصدر: Neurobiology of Disease, Vol 108, Iss, Pp 352-361 (2017)

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Cytoplasm, Mice, Transgenic, Biology, Severity of Illness Index, lcsh:RC321-571, Cell Line, Muscular Atrophy, Spinal, Random Allocation, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine, medicine, Animals, Rho kinase, Enzyme Inhibitors, RNA, Small Interfering, Extracellular Signal-Regulated MAP Kinases, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Rho-associated protein kinase, Motoneuron disease, Motor Neurons, rho-Associated Kinases, Cell Death, Kinase, Fasudil, Spinal muscular atrophy, SMA, medicine.disease, Signaling, Up-Regulation, ERK, Disease Models, Animal, Crosstalk (biology), 030104 developmental biology, Spinal Cord, nervous system, Neurology, Spinal Muscular Atrophy, Disease Progression, Benzimidazoles, Neuroscience, 030217 neurology & neurosurgery, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6c3c28def7f3d412db636da8a69670Test
https://doi.org/10.1016/j.nbd.2017.09.005Test

المؤلفون: Inga Stockbrügger, Sebastian Rademacher, Peter Claus, Hella Brinkmann, Natasha Broughton, Claudia Grothe, Niko Hensel

المصدر: Cellular Signalling. 26:540-548

مصطلحات موضوعية: MAPK/ERK pathway, Neurite, Pyridines, Motility, Biology, PC12 Cells, Cell Line, Muscular Atrophy, Spinal, Mice, Neurites, medicine, Animals, Enzyme Inhibitors, RNA, Small Interfering, Extracellular Signal-Regulated MAP Kinases, Rho-associated protein kinase, Actin, Cell Proliferation, rho-Associated Kinases, Receptor Protein-Tyrosine Kinases, SMN Complex Proteins, Cell Biology, Anatomy, Spinal muscular atrophy, SMA, medicine.disease, Amides, Receptors, Fibroblast Growth Factor, Rats, Cell biology, Pyridazines, Actin Cytoskeleton, Crosstalk (biology), Pyrimidines, Pyrazoles, RNA Interference

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f725739ca446b467a0526a02b2edc8Test
https://doi.org/10.1016/j.cellsig.2013.11.027Test

المؤلفون: Peter Claus, Michal K. Stachowiak, Hella Brinkmann, Benjamin Förthmann, Andreas Ratzka, Claudia Grothe

المصدر: Cellular and Molecular Life Sciences. 70:2555-2568

مصطلحات موضوعية: Gene isoform, congenital, hereditary, and neonatal diseases and abnormalities, Ribonucleoprotein, U4-U6 Small Nuclear, animal diseases, Population, Coiled Bodies, Biology, Cellular and Molecular Neuroscience, medicine, Humans, Protein Isoforms, snRNP, Protein Interaction Maps, Nuclear protein, education, Molecular Biology, Pharmacology, education.field_of_study, Nuclear Proteins, nutritional and metabolic diseases, Fluorescence recovery after photobleaching, SMN Complex Proteins, Cell Biology, Spinal muscular atrophy, medicine.disease, nervous system diseases, Cell biology, Muscular Atrophy, HEK293 Cells, medicine.anatomical_structure, nervous system, Cajal body, Biochemistry, Molecular Medicine, Fibroblast Growth Factor 2, Nucleus, Fluorescence Recovery After Photobleaching, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d74115274b66c730b161946db77c04Test
https://doi.org/10.1007/s00018-012-1242-8Test