نتائج البحث - "Helena Perez Pena"

1

دورية أكاديمية

Computational Approaches to the Rational Design of Tubulin-Targeting Agents

المؤلفون: Helena Pérez-Peña, Anne-Catherine Abel, Maxim Shevelev, Andrea E. Prota, Stefano Pieraccini, Dragos Horvath

المساهمون: H. Pérez-Peña, A. Abel, M. Shevelev, A.E. Prota, S. Pieraccini, D. Horvath

مصطلحات موضوعية: QSAR, computer-aided drug design, microtubule targeting agent, microtubule, molecular docking, molecular dynamics simulation, pharmacophore screening, virtual screening, Settore CHIM/02 - Chimica Fisica

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36830654; info:eu-repo/semantics/altIdentifier/wos/WOS:000938949400001; volume:13; issue:2; firstpage:1; lastpage:35; numberofpages:35; journal:BIOMOLECULES; https://hdl.handle.net/2434/956858Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85148965964

الإتاحة: https://doi.org/10.3390/biom13020285Test
https://hdl.handle.net/2434/956858Test

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2

دورية أكاديمية

Discovery of a Novel Trifluoromethyl Diazirine Inhibitor of SARS-CoV-2 Mpro

المؤلفون: Andrea Citarella, Davide Moi, Martina Pedrini, Helena Pérez-Peña, Stefano Pieraccini, Claudio Stagno, Nicola Micale, Tanja Schirmeister, Giulia Sibille, Giorgio Gribaudo, Alessandra Silvani, Daniele Passarella, Clelia Giannini

المصدر: Molecules; Volume 28; Issue 2; Pages: 514

مصطلحات موضوعية: SARS-CoV-2 M pro, diazirines, coronavirus, SARS-CoV-2, COVID-19, cysteine proteases, enzymatic inhibitors

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules28020514Test

الإتاحة: https://doi.org/10.3390/molecules28020514Test

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3

دورية أكاديمية

α-Synuclein: An All-Inclusive Trip Around its Structure, Influencing Factors and Applied Techniques

المؤلفون: Nicolò Bisi, Lucia Feni, Kaliroi Peqini, Helena Pérez-Peña, Sandrine Ongeri, Stefano Pieraccini, Sara Pellegrino

المصدر: Frontiers in Chemistry, Vol 9 (2021)

مصطلحات موضوعية: intrinsically disordered protein, synucleinopathy, secondary and tertiary structure, protein interaction, in silico studies, Chemistry, QD1-999

العلاقة: https://www.frontiersin.org/articles/10.3389/fchem.2021.666585/fullTest; https://doaj.org/toc/2296-2646Test; https://doaj.org/article/e04e2c7331384a49928be9456838938cTest

الإتاحة: https://doi.org/10.3389/fchem.2021.666585Test
https://doaj.org/article/e04e2c7331384a49928be9456838938cTest

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النص الكامل

4

دورية أكاديمية

Genomic analysis of Spanish wheat landraces reveals their variability and potential for breeding

المؤلفون: Laura Pascual, Magdalena Ruiz, Matilde López-Fernández, Helena Pérez-Peña, Elena Benavente, José Francisco Vázquez, Carolina Sansaloni, Patricia Giraldo

المصدر: BMC Genomics, Vol 21, Iss 1, Pp 1-17 (2020)

مصطلحات موضوعية: Wheat improvement, Local germplasm, GBS, DArTseq markers, SNP, Genetic diversity, Biotechnology, TP248.13-248.65, Genetics, QH426-470

العلاقة: https://doi.org/10.1186/s12864-020-6536-xTest; https://doaj.org/toc/1471-2164Test; https://doaj.org/article/1a7bcaf82b384257945f77eb0c5aaa77Test

الإتاحة: https://doi.org/10.1186/s12864-020-6536-xTest
https://doaj.org/article/1a7bcaf82b384257945f77eb0c5aaa77Test

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النص الكامل

5

دورية أكاديمية

Novel Cinnamic Esters as SARS-CoV-2 Mpro Inhibitors with In Vitro Activity against Human Coronaviruses

المؤلفون: Andrea Citarella, Davide Moi, Martina Pedrini, Helena Pérez-Peña, Stefano Pieraccini, Alessandro Dimasi, Claudio Stagno, Nicola Micale, Tanja Schirmeister, Giulia Sibille, Giorgio Gribaudo, Ales-sandra Silvani, Clelia Giannini, Daniele Passarella

المساهمون: Citarella, Andrea, Moi, Davide, Pedrini, Martina, Pérez-Peña, Helena, Pieraccini, Stefano, Dimasi, Alessandro, Stagno, Claudio, Micale, Nicola, Schirmeister, Tanja, Sibille, Giulia, Gribaudo, Giorgio, Silvani, Ales-sandra, Giannini, Clelia, Passarella, Daniele

مصطلحات موضوعية: SARS-CoV-2 Mpro, COVID-19, cysteine protease inhibitor, cinnamic ester, antiviral activity

وصف الملف: ELETTRONICO

العلاقة: volume:21; firstpage:3811; lastpage:3824; numberofpages:14; journal:ORGANIC & BIOMOLECULAR CHEMISTRY; https://hdl.handle.net/11570/3261910Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85153536760; https://www.scopus.com/record/display.uri?eid=2-s2.0-85153536760&origin=resultslist&sort=plf-f&src=s&st1=Micale&st2=Nicola&nlo=1&nlr=20&nls=afprfnm-t&affilName=University+of+Messina&sid=bca43e924985f31e21fe3c8c11fcdfde&sot=anl&sdt=aut&sl=34&s=AU-IDTest("Micale,+Nicola"+6602672514)&relpos=0&citeCnt=0&searchTerm=

الإتاحة: https://doi.org/10.1039/d3ob00381gTest
https://hdl.handle.net/11570/3261910Test
https://www.scopus.com/record/display.uri?eid=2-s2.0-85153536760&origin=resultslist&sort=plf-f&src=s&st1=Micale&st2=Nicola&nlo=1&nlr=20&nls=afprfnm-t&affilName=University+of+Messina&sid=bca43e924985f31e21fe3c8c11fcdfde&sot=anl&sdt=aut&sl=34&s=AU-IDTest("Micale,+Nicola"+6602672514)&relpos=0&citeCnt=0&searchTerm=

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6

Considerations around the SARS-CoV-2 Spike Protein with Particular Attention to COVID-19 Brain Infection and Neurological Symptoms

المؤلفون: Helena Perez Pena, Giulio Sancini, Stefano Pieraccini, Jessica Dragotto, Federico Iorio, Kambiz Hassanzadeh, Marco Feligioni, Lucia Buccarello

المساهمون: Hassanzadeh, K, Perez Pena, H, Dragotto, J, Buccarello, L, Iorio, F, Pieraccini, S, Sancini, G, Feligioni, M

المصدر: ACS Chemical Neuroscience

مصطلحات موضوعية: Physiology, viruses, Cognitive Neuroscience, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Pneumonia, Viral, Central nervous system, Cell, ACE2, Plasma protein binding, Biology, Biochemistry, Protein Structure, Secondary, Virus, Betacoronavirus, 03 medical and health sciences, 0302 clinical medicine, BIO/09 - FISIOLOGIA, medicine, Humans, Amino Acid Sequence, skin and connective tissue diseases, Receptor, Pandemics, 030304 developmental biology, Sequence (medicine), 0303 health sciences, SARS-CoV-2, Spike Protein, fungi, Brain, COVID-19, Cell Biology, General Medicine, Protein Structure, Tertiary, respiratory tract diseases, Cell biology, body regions, ACE2, Brain, COVID-19, Spike Protein, medicine.anatomical_structure, Spike Glycoprotein, Coronavirus, Nervous System Diseases, Coronavirus Infections, 030217 neurology & neurosurgery, Research Article

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537171bf97505487f10da9b379464b75Test
https://doi.org/10.1021/acschemneuro.0c00373Test

7

Conformational Flexibility of A Highly Conserved Helix Controls Cryptic Pocket Formation in FtsZ

المؤلفون: Raymond S. Norton, Helena Perez Pena, Aisha Alnami, Frank Kozielski, Shozeb Haider

المصدر: Journal of molecular biology. 433(15)

مصطلحات موضوعية: Models, Molecular, Protein Conformation, alpha-Helical, Cell division, macromolecular substances, Crystallography, X-Ray, physiological processes, Guanosine Diphosphate, Bacterial cell structure, Mycobacterium tuberculosis, 03 medical and health sciences, 0302 clinical medicine, Bacterial Proteins, Structural Biology, FtsZ, Molecular Biology, 030304 developmental biology, 0303 health sciences, Binding Sites, biology, Chemistry, 4-Hydroxycoumarins, biology.organism_classification, Cell biology, Cytoskeletal Proteins, Tubulin, Helix, biology.protein, bacteria, Guanosine Triphosphate, biological phenomena, cell phenomena, and immunity, Antibacterial activity, 030217 neurology & neurosurgery, Function (biology), Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9ec6a99a8fc979c182d5af04026ef4Test
https://pubmed.ncbi.nlm.nih.gov/34023403Test

8

Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus

المؤلفون: William J. Sullivan, Bermans J. Iskandar, Yasar Bayri, James R. Knight, James M. Johnston, Michael L.J. Apuzzo, Kristopher T. Kahle, Boyang Li, Andrew T. Timberlake, Sheng Chih Jin, Steven J. Schiff, Shreyas Panchagnula, Rebecca L. Walker, Shozeb Haider, Li Ge, Daniel H. Geschwind, Hannah Smith, Richard P. Lifton, Seth L. Alper, Carol Nelson-Williams, Boris Keren, Christine Hehnly, Arnaud Marlier, Bulent Guclu, Laura R. Ment, Ellen J. Hoffman, Francesco T. Mangano, Xue Zeng, Edith Mbabazi Kabachelor, Kaya Bilguvar, August A Allocco, Ashley Dunbar, James R. Broach, Benjamin C. Warf, William E. Butler, Helena Perez Pena, Sierra B Conine, David D. Limbrick, Qiongshi Lu, Edward R. Smith, Jason K. Karimy, Christopher Castaldi, Eric M. Jackson, Yener Sahin, Murat Gunel, Adam J. Kundishora, Charles C. Duncan, Michael L. DiLuna, Shrikant Mane, Michael C. Sierant, Gregory G. Heuer, June Goto, Charuta G. Furey, Andres Moreno-De-Luca, Peter Ssenyonga, Weilai Dong, Nenad Sestan, Phan Q. Duy, Benjamin C. Reeves, Tyrone DeSpenza, Irina Tikhonova

المساهمون: Jin, Sheng Chih, Dong, Weilai, Kundishora, Adam J., Panchagnula, Shreyas, Moreno-De-Luca, Andres, Furey, Charuta G., Allocco, August A., Walker, Rebecca L., Nelson-Williams, Carol, Smith, Hannah, Dunbar, Ashley, Conine, Sierra, Lu, Qiongshi, Zeng, Xue, Sierant, Michael C., Knight, James R., Sullivan, William, Duy, Phan Q., DeSpenza, Tyrone, Reeves, Benjamin C., Karimy, Jason K., Marlier, Arnaud, Castaldi, Christopher, Tikhonova, Irina R., Li, Boyang, Pena, Helena Perez, Broach, James R., Kabachelor, Edith M., Ssenyonga, Peter, Hehnly, Christine, Ge, Li, Keren, Boris, Timberlake, Andrew T., Goto, June, Mangano, Francesco T., Johnston, James M., Butler, William E., Warf, Benjamin C., Smith, Edward R., Schiff, Steven J., Limbrick, David D., Jr., Heuer, Gregory, Jackson, Eric M., Iskandar, Bermans J., Mane, Shrikant, Haider, Shozeb, Guclu, Bulent, Bayri, Yasar, Sahin, Yener, Duncan, Charles C., Apuzzo, Michael L. J., DiLuna, Michael L., Hoffman, Ellen J., Sestan, Nenad, Ment, Laura R., Alper, Seth L., Bilguvar, Kaya, Geschwind, Daniel H., Gunel, Murat, Lifton, Richard P., Kahle, Kristopher T.

المصدر: Nat Med

مصطلحات موضوعية: EXPRESSION, 0301 basic medicine, Male, PTEN, Cell type, Neurogenesis, Ubiquitin-Protein Ligases, CHILDREN, Disease, VENTRICULAR ZONE DISRUPTION, Bioinformatics, General Biochemistry, Genetics and Molecular Biology, Article, COWDEN-SYNDROME, Cerebral Ventricles, PATHWAY, Tripartite Motif Proteins, 03 medical and health sciences, 0302 clinical medicine, Cerebrospinal fluid, RARE, Neural Stem Cells, Pregnancy, Exome Sequencing, Medicine, Humans, Genetic Predisposition to Disease, Exome, AUTISM, Exome sequencing, Gliogenesis, SPECTRUM, Fetus, business.industry, Brain, General Medicine, medicine.disease, Neural stem cell, DE-NOVO MUTATION, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation, Female, business, Neuroglia, Ventriculomegaly, Transcription Factors, Hydrocephalus

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa5ffd2d8f3b89a9eace21cef26b4737Test
https://europepmc.org/articles/PMC7871900Test/

9

Repurposing erectile dysfunction drugs tadalafil and vardenafil to increase bone mass

المصدر: Proc Natl Acad Sci U S A

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a717792c82ab21401dc1124c66bdd462Test
https://pubmed.ncbi.nlm.nih.gov/32513693Test

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