المؤلفون: Linda Lowes, Navid Khan, Lindsay N. Alfano, Helen Eliopoulos, Nathalie Goemans, Eugenio Mercuri, Craig M. McDonald, Jerry R. Mendell, Nanshi Sha

المصدر: Journal of Neuromuscular Diseases

مصطلحات موضوعية: Research Report, Duchenne muscular dystrophy, Male, medicine.medical_specialty, BOYS, Neuromuscular disease, Adolescent, Clinical Neurology, Walk Test, Walking, Eteplirsen, dystrophin, Morpholinos, Internal medicine, loss of ambulation, END-POINTS, medicine, Humans, In patient, eteplirsen, Child, POPULATION, Retrospective Studies, Science & Technology, 6-minute walk test, biology, business.industry, Neurosciences, Exons, medicine.disease, Duchenne, Exon skipping, PREVALENCE, Natural history, Muscular Dystrophy, Duchenne, Neurology, Case-Control Studies, Ambulatory, Mutation, biology.protein, Neurology (clinical), Neurosciences & Neurology, MUSCLE DISEASE, Dystrophin, business, Life Sciences & Biomedicine, EXONDYS 51

وصف الملف: Print

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a2b68443493fe625b361d1d42ed491Test
http://europepmc.org/articles/PMC8385516Test

المؤلفون: Frederick J. Schnell, Amy Flynt, Jessie Lynch, Helen Eliopoulos, Cas Donoghue, Linda Lowes, Jerry R. Mendell, Anthony J. Milici, Emily Naughton, D. Frank, Sarah Lewis, Johannes Dworzak, Karin Lucas, Zarife Sahenk, Robert Dracker, Linda H. Cripe, Jay S. Charleston, G. David Young, Anne M. Connolly, Lindsay N. Alfano, Louise R. Rodino-Klapac

المصدر: Medicine

مصطلحات موضوعية: musculoskeletal diseases, Male, congenital, hereditary, and neonatal diseases and abnormalities, Pediatrics, medicine.medical_specialty, Long term treatment, Duchenne muscular dystrophy, MEDLINE, Observational Study, Walk Test, Walking, Eteplirsen, Severity of Illness Index, dystrophin, law.invention, Morpholinos, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, Double-Blind Method, law, Severity of illness, Diseases in Twins, upper extremity, Medicine, Humans, echocardiography, In patient, 030212 general & internal medicine, Muscular dystrophy, RNA Processing, Post-Transcriptional, Child, business.industry, vital capacity, left ventricular ejection fraction, ventricular dysfunction, General Medicine, medicine.disease, 3. Good health, Muscular Dystrophy, Duchenne, Treatment Outcome, 030220 oncology & carcinogenesis, Disease Progression, business, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a723d5cf41ea1e9e860c4bea7d51813aTest
https://pubmed.ncbi.nlm.nih.gov/31261494Test

المؤلفون: Erik K Henricson, Navid Khan, Linda Lowes, Helen Eliopoulos, Heather Gordish-Dressman, Craig M. McDonald, Lixin Han, T. Bernard Kinane, Jerry R. Mendell

المصدر: Journal of Neuromuscular Diseases

مصطلحات موضوعية: 0301 basic medicine, Male, Research Report, medicine.medical_specialty, Adolescent, Duchenne muscular dystrophy, Vital Capacity, Eteplirsen, Morpholinos, Dystrophin, 03 medical and health sciences, FEV1/FVC ratio, 0302 clinical medicine, Exondys 51, Internal medicine, Medicine, Humans, Respiratory system, Child, Clinical Trials as Topic, business.industry, Respiration, medicine.disease, Interim analysis, forced expiratory volume, 3. Good health, Muscular Dystrophy, Duchenne, 030104 developmental biology, Neurology, Ambulatory, Neurology (clinical), Non ambulatory, business, 030217 neurology & neurosurgery, Natural history study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54e4ca6959653916d9f5cd06ef53f63Test
https://pubmed.ncbi.nlm.nih.gov/30856119Test

المؤلفون: Rita Tiehen, Terri L. Leahy, Vincent L. Giranda, Gary Gordon, Helen Eliopoulos, Robert A. Carr

المصدر: Clinical Cancer Research. 14:3683-3688

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Time Factors, Drug Industry, Disease, Poly(ADP-ribose) Polymerase Inhibitors, Models, Biological, Phase (combat), Humans, Medicine, Enzyme Inhibitors, Intensive care medicine, Clinical Trials as Topic, Clinical Trials, Phase I as Topic, business.industry, Mechanism (biology), Drug discovery, Clinical study design, Perspective (graphical), Clinical trial, Oncology, Drug development, Drug Design, Benzimidazoles, business, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d697f271c075f906a0e2d9992e7abdTest
https://doi.org/10.1158/1078-0432.ccr-07-4586Test

المؤلفون: Lee J. Helman, Gary B. Gordon, Seth M. Steinberg, James H. Doroshow, Shivaani Kummar, Jerry M. Collins, Larry Rubinstein, Anne Monks, Robert J. Kinders, Helen Eliopoulos, Robert H. Wiltrout, Jennifer A. Low, Anthony J. Murgo, Lawrence R. Phillips, Martin Gutierrez, Joseph E. Tomaszewski, Ralph E. Parchment, Vincent L. Giranda, Jiuping Ji, Alice P. Chen

المصدر: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 27(16)

مصطلحات موضوعية: Oncology, Male, Cancer Research, medicine.medical_specialty, Pathology, Veliparib, Biopsy, Administration, Oral, Biological Availability, Antineoplastic Agents, Poly(ADP-ribose) Polymerase Inhibitors, Peripheral blood mononuclear cell, Poly (ADP-Ribose) Polymerase Inhibitor, chemistry.chemical_compound, Pharmacokinetics, Internal medicine, Neoplasms, Original Reports, Clinical endpoint, medicine, Humans, Enzyme Inhibitors, Aged, Clinical Trials, Phase I as Topic, Dose-Response Relationship, Drug, business.industry, Investigational New Drug, Middle Aged, Clinical trial, Treatment Outcome, chemistry, Research Design, Pharmacodynamics, Leukocytes, Mononuclear, Feasibility Studies, Benzimidazoles, Female, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeef62c0315c626883152427d77f41beTest
https://pubmed.ncbi.nlm.nih.gov/19364952Test

المؤلفون: Anne E. Hagey, Ann M. Mauer, Moacyr Ribeiro de Oliveira, Andrew Coates, Xiangdong Zhou, Charles M. Rudin, Helen Eliopoulos, Hao Xiong

المصدر: Journal of Thoracic Oncology. 2(8)

مصطلحات موضوعية: Oncology, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Pemetrexed, business.industry, Internal medicine, Medicine, non-small cell lung cancer (NSCLC), business, medicine.disease, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888fac75575c1fd95b07336fca3e147aTest

المؤلفون: Hao Xiong, Nashat Gabrail, Xiangdong Zhou, Helen Eliopoulos, Andrew Coates, Anne E. Hagey

المصدر: Journal of Thoracic Oncology. 2:S672

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Oncology, medicine.medical_specialty, Docetaxel, business.industry, Internal medicine, medicine, Non small cell, business, Lung cancer, medicine.disease, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c383de7144783ddcbd6dd07a8e135d15Test
https://doi.org/10.1097/01.jto.0000283959.90967.3bTest

المساهمون: Helen Eliopoulos, MD, Global Project Head

المصدر: A Phase 1/2 Study Evaluating the Safety and Efficacy of ABT-751 in Combination With Docetaxel Versus Docetaxel Alone in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT00354562Test