المؤلفون: Haritha L. Desu, Katherine M. Sawicka, Emily Wuerch, Vanessa Kitchin, Jacqueline A. Quandt

المصدر: Frontiers in Neurology, Vol 15 (2024)

مصطلحات موضوعية: multiple sclerosis, biomarkers, progression, neurofilament light, neurodegeneration, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fneur.2024.1382468/fullTest; https://doaj.org/toc/1664-2295Test

الوصول الحر: https://doaj.org/article/773a1ef78dab466bb65a4bb84721281bTest

المؤلفون: Melanie J. Plastini, Haritha L. Desu, Maureen C. Ascona, Anna L. Lang, Mario A. Saporta, Roberta Brambilla

المصدر: Frontiers in Cellular Neuroscience, Vol 16 (2022)

مصطلحات موضوعية: oligodendrocytes, human induced pluripotent stem cells, primary progressive multiple sclerosis, RNA-sequencing, inflammasome, NLRP2, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fncel.2022.972144/fullTest; https://doaj.org/toc/1662-5102Test

الوصول الحر: https://doaj.org/article/ddd1152b94984375b60a9db4320d69f4Test

المؤلفون: Hélène Jamann, Qiao-Ling Cui, Haritha L. Desu, Florian Pernin, Olivier Tastet, Alexandre Halaweh, Negar Farzam-kia, Victoria Hannah Mamane, Oumarou Ouédraogo, Aurélie Cleret-Buhot, Audrey Daigneault, Renaud Balthazard, Wendy Klement, Florent Lemaître, Nathalie Arbour, Jack Antel, Jo Anne Stratton, Catherine Larochelle

المصدر: Frontiers in Immunology, Vol 13 (2022)

مصطلحات موضوعية: human oligodendrocytes, neuroinflammation, multiple sclerosis, Th17 cells, granzyme B, CD4 T lymphocytes, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fimmu.2022.850616/fullTest; https://doaj.org/toc/1664-3224Test

الوصول الحر: https://doaj.org/article/53dccdeea5ea49b3b922cab52828fef2Test

المؤلفون: Haritha L. Desu, Melanie Plastini, Placido Illiano, Helen M. Bramlett, W. Dalton Dietrich, Juan Pablo de Rivero Vaccari, Roberta Brambilla, Robert W. Keane

المصدر: Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-10 (2020)

مصطلحات موضوعية: IC100, Inflammasome, Neuroinflammation, Multiple sclerosis, Experimental autoimmune encephalomyelitis, Caspase-1, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

العلاقة: http://link.springer.com/article/10.1186/s12974-020-01826-0Test; https://doaj.org/toc/1742-2094Test

الوصول الحر: https://doaj.org/article/a2ae2648a12f473282b2b1f1e7ecdb86Test

المؤلفون: Melanie J. Plastini, Haritha L. Desu, Roberta Brambilla

المصدر: Frontiers in Cellular Neuroscience, Vol 14 (2020)

مصطلحات موضوعية: microglia, neuroinflammation, neurorepair, multiple sclerosis, neurological disease, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/article/10.3389/fncel.2020.00269/fullTest; https://doaj.org/toc/1662-5102Test

الوصول الحر: https://doaj.org/article/30103bbb6378495b82d02bcc6ca91709Test

المؤلفون: Haritha L. Desu, Placido Illiano, James S. Choi, Maureen C. Ascona, Han Gao, Jae K. Lee, Roberta Brambilla

المصدر: Cells, Vol 10, Iss 7, p 1785 (2021)

مصطلحات موضوعية: oligodendrocytes, neuroinflammation, remyelination, cytokines, TNF, multiple sclerosis, Cytology, QH573-671

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/2073-4409/10/7/1785Test; https://doaj.org/toc/2073-4409Test

الوصول الحر: https://doaj.org/article/c82a87df9beb4f83949427dacf3e0f79Test

المؤلفون: Haritha L. Desu, Katherine M. Sawicka, Emily Wuerch, Vanessa Kitchin, Jacqueline A. Quandt

مصطلحات موضوعية: Neurology and Neuromuscular Diseases, Neurogenetics, multiple sclerosis, biomarkers, progression, neurofilament light, neurodegeneration

العلاقة: https://figshare.com/articles/dataset/Data_Sheet_1_A_rapid_review_of_differences_in_cerebrospinal_neurofilament_light_levels_in_clinical_subtypes_of_progressive_multiple_sclerosis_DOCX/25566609Test

الإتاحة: https://doi.org/10.3389/fneur.2024.1382468.s001Test
https://figshare.com/articles/dataset/Data_Sheet_1_A_rapid_review_of_differences_in_cerebrospinal_neurofilament_light_levels_in_clinical_subtypes_of_progressive_multiple_sclerosis_DOCX/25566609Test

المؤلفون: Jakob S. Pallesen (10525673), Dilip Narayanan (4223695), Kim T. Tran (7313468), Sara M. Ø. Solbak (7313474), Giuseppe Marseglia (6505253), Louis M. E. Sørensen (10525676), Lars J. Høj (10525679), Federico Munafò (10525682), Rosa M. C. Carmona (7313480), Anthony D. Garcia (6611543), Haritha L. Desu (8798495), Roberta Brambilla (3429644), Tommy N. Johansen (1435300), Grzegorz M. Popowicz (179378), Michael Sattler (17373), Michael Gajhede (73263), Anders Bach (412488)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Mental Health, Chemical Sciences not elsewhere classified, 17 fragment hits, factor erythroid 2-, Kelch-like ECH-associated protein 1, interaction, FBDR, Deconstructing Noncovalent Kelch-li., K i values, Keap 1 Kelch binding pocket, X-ray crystallography, inhibitor, PPI, fragment-based deconstruction recon., Reconstruct New Potent Compounds Ta., 16 μ M

العلاقة: https://figshare.com/articles/journal_contribution/Deconstructing_Noncovalent_Kelch-like_ECH-Associated_Protein_1_Keap1_Inhibitors_into_Fragments_to_Reconstruct_New_Potent_Compounds/14371859Test

الإتاحة: https://doi.org/10.1021/acs.jmedchem.0c02094.s001Test

المؤلفون: Roberta Brambilla, Melanie J. Plastini, Robert W. Keane, Placido Illiano, W. Dalton Dietrich, Haritha L. Desu, Juan Pablo de Rivero Vaccari, Helen M. Bramlett

المصدر: Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-10 (2020)
Desu, H L, Plastini, M, Illiano, P, Bramlett, H M, Dietrich, W D, De Rivero Vaccari, J P, Brambilla, R & Keane, R W 2020, ' IC100 : A novel anti-ASC monoclonal antibody improves functional outcomes in an animal model of multiple sclerosis ', Journal of Neuroinflammation, vol. 17, 143 . https://doi.org/10.1186/s12974-020-01826-0Test
Journal of Neuroinflammation

مصطلحات موضوعية: Encephalomyelitis, Autoimmune, Experimental, Immunology, Caspase 1, Antibodies, Monoclonal, Humanized, ASC, lcsh:RC346-429, Myelin oligodendrocyte glycoprotein, Inflammasome, Multiple sclerosis, Cellular and Molecular Neuroscience, Mice, Neuroinflammation, medicine, Animals, Humans, lcsh:Neurology. Diseases of the nervous system, Experimental autoimmune encephalomyelitis, biology, Microglia, business.industry, IL-1, General Neuroscience, Research, Antibodies, Monoclonal, PYCARD, Recovery of Function, medicine.disease, CARD Signaling Adaptor Proteins, Mice, Inbred C57BL, Pycard, medicine.anatomical_structure, Neurology, Spinal Cord, Caspase-1, biology.protein, Female, business, IC100, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8deda68dbd535dc8da7d57e55475456aTest
http://link.springer.com/article/10.1186/s12974-020-01826-0Test

المؤلفون: Hélène Jamann, Qiao-Ling Cui, Haritha L. Desu, Florian Pernin, Olivier Tastet, Alexandre Halaweh, Negar Farzam-kia, Victoria Hannah Mamane, Oumarou Ouédraogo, Aurélie Cleret-Buhot, Audrey Daigneault, Renaud Balthazard, Wendy Klement, Florent Lemaître, Nathalie Arbour, Jack Antel, Jo Anne Stratton, Catherine Larochelle

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, human oligodendrocytes, neuroinflammation, multiple sclerosis, Th17 cells, granzyme B, CD4 T lymphocytes

العلاقة: https://figshare.com/articles/dataset/DataSheet_1_Contact-Dependent_Granzyme_B-Mediated_Cytotoxicity_of_Th17-Polarized_Cells_Toward_Human_Oligodendrocytes_docx/19569844Test

الإتاحة: https://doi.org/10.3389/fimmu.2022.850616.s001Test
https://figshare.com/articles/dataset/DataSheet_1_Contact-Dependent_Granzyme_B-Mediated_Cytotoxicity_of_Th17-Polarized_Cells_Toward_Human_Oligodendrocytes_docx/19569844Test