المؤلفون: Melanie Hüttenrauch, Isabella Ogorek, Hans Klafki, Markus Otto, Christine Stadelmann, Sascha Weggen, Jens Wiltfang, Oliver Wirths

المصدر: Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-14 (2018)

مصطلحات موضوعية: Alzheimer’s disease (AD), Glycoprotein nonmetastatic melanoma protein B (GPNMB), Neuroinflammation, Activated microglia, Sporadic AD patients, Transgenic mice, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

العلاقة: http://link.springer.com/article/10.1186/s40478-018-0612-3Test; https://doaj.org/toc/2051-5960Test

الوصول الحر: https://doaj.org/article/f5c9a902a8144fa4878aa4d1c4c44cdbTest

المؤلفون: Johanna Giuranna, Anna-Lena Volckmar, Anna Heinen, Triinu Peters, Börge Schmidt, Anne Spieker, Helena Straub, Harald Grallert, Timo D. Müller, Jochen Antel, Ute Haußmann, Hans Klafki, Rui Liangyou, Johannes Hebebrand, Anke Hinney

المصدر: Obesity Facts, Vol 11, Iss 2, Pp 93-108 (2018)

مصطلحات موضوعية: GWAS, SH2B1, JAK, STAT, IRS, Expression genome-wide, Locus, Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627

وصف الملف: electronic resource

العلاقة: https://www.karger.com/Article/FullText/486962Test; https://doaj.org/toc/1662-4025Test; https://doaj.org/toc/1662-4033Test

الوصول الحر: https://doaj.org/article/46de7f0510914b3f8e715b0c94aa8102Test

المؤلفون: Jonathan Vogelgsang, Hans Klafki, Barbara Morgado, Anke Jahn‐Brodmann, Hermann Esselmann, Chris Bauer, Johannes Schuchhardt, Oliver Peters, Josef Priller, Anja Schneider, Klaus Fliessbach, Frank Jessen, Emrah Duzel, Katharina Buerger, Robert Perneczky, Stefan Teipel, Christoph Laske, Annika Spottke, Michael T. Heneka, Alfredo Ramirez, Jens Wiltfang

المصدر: Alzheimer's & Dementia. 18

مصطلحات موضوعية: Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b0ad1520833e934f7d07f85f4a976acfTest
https://doi.org/10.1002/alz.063242Test

المؤلفون: Krishyanthy Sritharen, Hans Klafki, Thomas A. Bayer, Oliver Wirths, Luke A. Miles, Jorge Ghiso, Silvia Zampar, Jens Wiltfang, Agueda Rostagno

المصدر: Neuropathology & applied neurobiology 46(7), 673-685 (2020). doi:10.1111/nan.12637
Neuropathology and applied neurobiology

مصطلحات موضوعية: 0301 basic medicine, N-terminal truncation, Plaque, Amyloid, pharmacology [Antibodies, Monoclonal, Humanized], 0302 clinical medicine, antibody, metabolism [Peptide Fragments], Aged, 80 and over, biology, Chemistry, Brain, amyloid, Human brain, 3. Good health, medicine.anatomical_structure, capillary isoelectric focusing immunoassay, Neurology, Immunohistochemistry, Alzheimer disease, Alzheimer's disease, Antibody, metabolism [Alzheimer Disease], medicine.drug, Histology, Amyloid, metabolism [Amyloid beta-Peptides], Antibodies, Monoclonal, Humanized, Article, Pathology and Forensic Medicine, 03 medical and health sciences, Alzheimer Disease, Physiology (medical), medicine, Extracellular, Animals, Humans, Bapineuzumab, ddc:610, Aged, Amyloid beta-Peptides, medicine.disease, Molecular biology, Peptide Fragments, metabolism [Plaque, Amyloid], Disease Models, Animal, 030104 developmental biology, metabolism [Brain], Crenezumab, biology.protein, Abeta, Neurology (clinical), 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3713b3f530ca4d6db198df18f5107c49Test
https://doi.org/10.1111/nan.12637Test

المؤلفون: Louise L. Busk, Martin Dufva, Hans Klafki, Helen Webb, Markus Otto, Andreas H. Kunding, Jörg Peter Kutter

المصدر: Lab on a Chip. 18:2797-2805

مصطلحات موضوعية: 0301 basic medicine, Materials science, Transcription, Genetic, Air water interface, Two step, Biomedical Engineering, Bioengineering, 02 engineering and technology, Polymerase Chain Reaction, Biochemistry, law.invention, 03 medical and health sciences, law, Lab-On-A-Chip Devices, Spark plug, Aqueous solution, Air, technology, industry, and agriculture, Water, Femtoliter, General Chemistry, 021001 nanoscience & nanotechnology, Fluorescence, eye diseases, Superhydrophobic coating, 030104 developmental biology, Chemical engineering, Protein Biosynthesis, Water chemistry, 0210 nano-technology, Hydrophobic and Hydrophilic Interactions

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2000887c82d3a4ed50191656fa51a7Test
https://doi.org/10.1039/c8lc00608cTest

المؤلفون: Silvia Zampar, Karen Hornung, Thomas Liepold, Hans Klafki, Olaf Jahn, Jens Wiltfang, Nadine Engel, Oliver Wirths, Thomas A. Bayer

المصدر: Journal of Alzheimer's disease 67(3), 849-858 (2019). doi:10.3233/JAD-181134

مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Male, metabolism [Amyloid beta-Peptides], Mice, Transgenic, Hippocampal formation, Mass Spectrometry, 03 medical and health sciences, Mice, 0302 clinical medicine, In vivo, Animals, Humans, ddc:610, Neprilysin, chemistry.chemical_classification, Neurons, Metalloproteinase, Amyloid beta-Peptides, General Neuroscience, fungi, Substrate (chemistry), metabolism [Neprilysin], General Medicine, In vitro, Cell biology, Psychiatry and Mental health, Clinical Psychology, 030104 developmental biology, Enzyme, chemistry, metabolism [Neurons], Female, Geriatrics and Gerontology, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d650049911a1a5828ae18c70084ba2e3Test
https://pubmed.ncbi.nlm.nih.gov/30664509Test

المؤلفون: Hans Klafki, Jonas Schartner, Carsten Kötting, Just Genius, Andreas Nabers, Klaus Gerwert, Henning Hafermann, Julian Ollesch, Jens Wiltfang

المصدر: Analytical chemistry 88(5), 2755-2762 (2016). doi:10.1021/acs.analchem.5b04286

مصطلحات موضوعية: Male, 0301 basic medicine, Medizin, Peptide, cerebrospinal fluid [Amyloid beta-Peptides], Protein Structure, Secondary, Analytical Chemistry, 03 medical and health sciences, blood [Alzheimer Disease], 0302 clinical medicine, Protein structure, Cerebrospinal fluid, Alzheimer Disease, blood [Amyloid beta-Peptides], Blood plasma, medicine, Humans, Prospective Studies, Protein secondary structure, Aged, Body fluid, chemistry.chemical_classification, blood [Biomarkers], Amyloid beta-Peptides, Chemistry, Middle Aged, medicine.disease, Molecular biology, cerebrospinal fluid [Alzheimer Disease], 030104 developmental biology, cerebrospinal fluid [Biomarkers], Biochemistry, ddc:540, Biomarker (medicine), Female, chemistry [Amyloid beta-Peptides], Alzheimer's disease, Biomarkers, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::080b066b72e021b2a0e329d7ba8ad280Test
https://doi.org/10.1021/acs.analchem.5b04286Test

المؤلفون: Jens Wiltfang, Jonathan Vogelgsang, Hans Klafki

المصدر: Biomarkers for Alzheimer’s Disease Drug Development ISBN: 9781493977031
New York, NY : Springer New York, Methods in Molecular Biology 1750, 111-124 (2018). doi:10.1007/978-1-4939-7704-8_7
Biomarkers for Alzheimer’s Disease Drug Development / Perneczky, Robert (Editor) ; New York, NY : Springer New York, 2018, Chapter 7 ; ISSN: 1064-3745=1940-6029 ; ISBN: 978-1-4939-7703-1=978-1-4939-7704-8 ; doi:10.1007/978-1-4939-7704-8

مصطلحات موضوعية: 0301 basic medicine, Detection limit, blood [Biomarkers], Chromatography, Amyloid β, medicine.diagnostic_test, Human blood, Chemiluminescence immunoassay, Chemistry, methods [Immunoassay], diagnosis [Alzheimer Disease], methods [Luminescent Measurements], 03 medical and health sciences, Technical performance, blood [Alzheimer Disease], 030104 developmental biology, 0302 clinical medicine, ddc:570, Immunoassay, blood [Amyloid beta-Peptides], medicine, Humans, Electrochemiluminescence, Sample dilution, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1382df8a1f95b7a8fd65745db880e32Test
https://doi.org/10.1007/978-1-4939-7704-8_7Test

المؤلفون: Jens Wiltfang, Steffen Halbgebauer, Ute Haußmann, Markus Otto, Hayrettin Tumani, Hans Klafki

المصدر: ELECTROPHORESIS. 36:355-362

مصطلحات موضوعية: Adult, Male, Multiple Sclerosis, Immunoblotting, Clinical Biochemistry, Medizin, Intrathecal, Sensitivity and Specificity, Biochemistry, Analytical Chemistry, Silver stain, chemistry.chemical_compound, Cerebrospinal fluid, Limit of Detection, medicine, Humans, Nanotechnology, In patient, Immunoassay, Inflammation, Chromatography, medicine.diagnostic_test, Isoelectric focusing, Multiple sclerosis, Oligoclonal Bands, Electrophoresis, Capillary, Reproducibility of Results, Middle Aged, medicine.disease, Molecular biology, 3. Good health, chemistry, Case-Control Studies, Immunoglobulin G, Agarose, Electrophoresis, Polyacrylamide Gel, Female, Isoelectric Focusing

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbbdcee979839943e5d34d99571e21edTest
https://doi.org/10.1002/elps.201400339Test

المؤلفون: Steffen Halbgebauer, Magdalena Nagl, Hans Klafki, Ute Haußmann, Petra Steinacker, Patrick Oeckl, Jan Kassubek, Elmar Pinkhardt, Albert C. Ludolph, Hilkka Soininen, Sanna-Kaisa Herukka, Jens Wiltfang, Markus Otto

المصدر: Scientific Reports

مصطلحات موضوعية: Aged, 80 and over, Male, Parkinson Disease, Middle Aged, Prognosis, Risk Assessment, Article, alpha 1-Antitrypsin, Humans, Dementia, Female, Isoelectric Focusing, Biomarkers, Aged

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cf0d24d260fdcddf45e3fc5c7861ab71Test
http://europepmc.org/articles/PMC4868992Test