المؤلفون: Luo, Huacheng, Zhu, Ganqian, Eshelman, Melanie A., Fung, Tsz Kan, Lai, Qian, Wang, Fei, Zeisig, Bernd B., Lesperance, Julia, Ma, Xiaoyan, Chen, Shi, Cesari, Nicholas, Cogle, Christopher, Chen, Baoan, Xu, Bing, Yang, Feng Chun, So, Chi Wai Eric, Qiu, Yi, Xu, Mingjiang, Huang, Suming

المصدر: Luo , H , Zhu , G , Eshelman , M A , Fung , T K , Lai , Q , Wang , F , Zeisig , B B , Lesperance , J , Ma , X , Chen , S , Cesari , N , Cogle , C , Chen , B , Xu , B , Yang , F C , So , C W E , Qiu , Y , Xu , M & Huang , S 2022 , ' HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia ' , MOLECULAR ....

مصطلحات موضوعية: AML leukemogenesis, canonical Wnt transcription, cohesin complex, CTCF chromatin boundary, enhancer/promoter interactions, HOTTIP lncRNA, R-loops, TAD formation

الإتاحة: https://doi.org/10.1016/j.molcel.2022.01.014Test
https://kclpure.kcl.ac.uk/portal/en/publications/b2f00eef-58d1-4ecd-a319-171189634bc9Test
http://www.scopus.com/inward/record.url?scp=85124504701&partnerID=8YFLogxKTest

المؤلفون: Luo, Huacheng, Zhu, Ganqian, Xu, Jianfeng, Lai, Qian, Yan, Bowen, Guo, Ying, Fung, Tsz Kan, Zeisig, Bernd B., Cui, Ya, Zha, Jie, Cogle, Christopher, Wang, Fei, Xu, Bing, Yang, Feng Chun, Li, Wei, So, Chi Wai Eric, Qiu, Yi, Xu, Mingjiang, Huang, Suming

المصدر: Luo , H , Zhu , G , Xu , J , Lai , Q , Yan , B , Guo , Y , Fung , T K , Zeisig , B B , Cui , Y , Zha , J , Cogle , C , Wang , F , Xu , B , Yang , F C , Li , W , So , C W E , Qiu , Y , Xu , M & Huang , S 2019 , ' HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice ' , CANCER ....

مصطلحات موضوعية: chromatin domain, CTCF boundary, enhancer/promoter accessibility, HOTTIP lncRNA, HOTTIP transgenic mice, HOX and hematopoietic gene regulation, HSC self-renewal, leukemia, WNT signaling targets

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1016/j.ccell.2019.10.011Test
https://kclpure.kcl.ac.uk/portal/en/publications/70ccd371-65ad-48dd-9dd4-e10978ed39c1Test
https://kclpure.kcl.ac.uk/ws/files/122190815/final_hottip_submitted_version_ES.pdfTest
http://www.scopus.com/inward/record.url?scp=85075878690&partnerID=8YFLogxKTest

المؤلفون: Feng Chun Yang, Fei Wang, Bing Xu, Bernd B. Zeisig, Suming Huang, Ganqian Zhu, Chi Wai Eric So, Ya Cui, Bowen Yan, Yi Qiu, Qian Lai, Huacheng Luo, Tsz Kan Fung, Ying Guo, Christopher R. Cogle, Jie Zha, Wei Li, Mingjiang Xu, Jianfeng Xu

المصدر: Luo, H, Zhu, G, Xu, J, Lai, Q, Yan, B, Guo, Y, Fung, T K, Zeisig, B B, Cui, Y, Zha, J, Cogle, C, Wang, F, Xu, B, Yang, F C, Li, W, So, C W E, Qiu, Y, Xu, M & Huang, S 2019, ' HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice ', CANCER CELL, vol. 36, no. 6, pp. 645-659.E8 . https://doi.org/10.1016/j.ccell.2019.10.011Test
Cancer cell

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, HOX and hematopoietic gene regulation, Biology, WNT signaling targets, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, Transcription (biology), enhancer/promoter accessibility, medicine, Animals, Cell Self Renewal, Hox gene, Cell Proliferation, Homeodomain Proteins, Gene Expression Regulation, Leukemic, leukemia, HOTTIP transgenic mice, Myeloid leukemia, Hematopoietic stem cell, Cell Biology, Hematopoietic Stem Cells, Chromatin, HSC self-renewal, Cell biology, Leukemia, Myeloid, Acute, Haematopoiesis, 030104 developmental biology, medicine.anatomical_structure, HOTTIP lncRNA, Oncology, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, CTCF boundary, RNA, Long Noncoding, chromatin domain, Homeotic gene, Reprogramming

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9f7f066edb92a8633d26640a10c078Test
https://doi.org/10.1016/j.ccell.2019.10.011Test