المؤلفون: Liming Chen, Junjie Zhu, Lirong Zhang, Xiaochao Ma, Xueyan Shao, Pei Wang, Xiao-bo Zhong, Yifan Bao

المصدر: Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 171-185 (2020)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: HFD, high-fat diet, HNF4α, hepatocyte nuclear factor 4 alpha, O-18-LA, offspring from parental mice fed with 18 weeks LFD, BMI, body mass index, Overweight, O-18-HA, offspring from parental mice fed with 18 weeks HFD, 0302 clinical medicine, 4-HA, adult mice fed with 4 weeks HFD, Nuclear receptors, EFV, efavirenz, O-8-LA, offspring from parental mice fed with 8 weeks LFD, SULT1A1, sulfotransferase 1A1, General Pharmacology, Toxicology and Pharmaceutics, 2. Zero hunger, 0303 health sciences, MPA, mobile phase A, PXR, pregnane X receptor, Diet-induced obesity, CYP2E1, cytochrome P450 2E1, 18-HA, adult mice fed with 18 weeks HFD, 7-ER, 7-ethoxyresorufin, 3. Good health, Drug metabolizing enzymes, High-fat diet, 18-LA, adult mice fed with 18 weeks LFD, AhR, aryl hydrocarbon receptor, 030220 oncology & carcinogenesis, 4-LA, adult mice fed with 4 weeks LFD, MDZ, midazolam, DMEs, drug-metabolizing enzymes, medicine.symptom, Drug-metabolizing enzymes, CAR, constitutive androstane receptor, Original article, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, RSF, resorufin, Ontogenic expression, MPB, mobile phase B, O-4-LA, offspring from parental mice fed with 4 weeks LFD, Offspring, PBS, phosphate-buffered saline, 8-HA, adult mice fed with 8 weeks HFD, Gapdh, glyceraldehyde-3-phosphate dehydrogenase, O-8-HA, offspring from parental mice fed with 8 weeks HFD, 03 medical and health sciences, Internal medicine, medicine, 030304 developmental biology, PPARα, peroxisome proliferator-activated receptor alpha, business.industry, lcsh:RM1-950, DIO, diet-induced obesity, RT-qPCR, real-time quantitative PCR, NADPH, nicotinamide adenine dinucleotide phosphate, Severe obesity, medicine.disease, Differential effects, Obesity, LFD, low-fat diet, Endocrinology, lcsh:Therapeutics. Pharmacology, Nuclear receptor, CHZ, chlorzoxazone, UGT1A1, uridine diphosphate glucuronosyltransferase 1A1, O-4-HA, offspring from parental mice fed with 4 weeks HFD, NRs, nuclear receptors, SD, standard deviation, business, 8-LA, adult mice fed with 8 weeks LFD, Ahr aryl hydrocarbon receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94cf0a5fdc606267df866d8be623f019Test
http://www.sciencedirect.com/science/article/pii/S2211383519308585Test

المؤلفون: Michelangelo Foti, Olivia Bejuy, Christine Maeder, Marta Correia de Sousa, Monika Gjorgjieva, Claudio De Vito, Laura Rubbia-Brandt, Dobrochna Dolicka, Margot Fournier, Cyril Sobolewski, Didier J. Colin, Flavien Berthou, Perry J. Blackshear

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology (2020)

مصطلحات موضوعية: 0301 basic medicine, Liver Cirrhosis, Male, HNF4α, hepatocyte nuclear factor 4 alpha, Carcinogenesis, Tristetraprolin, Datasets as Topic, GEPIA, Gene Expression Profiling Interactive Analysis, Tumor initiation, ddc:616.07, DMSO, dimethyl sulfoxide, LTTPKO, liver-specific tristetraprolin knockout mice, Mice, 0302 clinical medicine, Liver Neoplasms, Experimental, GSEA, gene set enrichment analysis, Fibrosis, Non-alcoholic Fatty Liver Disease, hemic and lymphatic diseases, 5-AZA, 5-aza-2'deoxycytidine, EGR1, early growth response 1, TSA, trichostatin A, heterocyclic compounds, Diethylnitrosamine, TGFβ, transforming growth factor beta, RNA-Seq, Original Research, TCGA, the cancer genome atlas, ICC, intrahepatic cholangiocarcinoma, MCD, methionine and choline-deficient, GEO, gene expression omnibus, TTP, tristetraprolin, Liver Neoplasms, Gastroenterology, NASH, respiratory system, Prognosis, HNF4A, Gene Expression Regulation, Neoplastic, UTR, untranslated region, Liver, FLX, floxed allele, 030211 gastroenterology & hepatology, Female, medicine.symptom, Hepatocyte dedifferentiation, EMT, epithelial-mesenchymal transition, therapeutics, NASH, nonalcoholic steatohepatitis, Liver Cancer, Carcinoma, Hepatocellular, IL6, interleukin 6, Primary Cell Culture, ARE, adenylate-uridylate-rich element, Down-Regulation, Inflammation, TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling, 03 medical and health sciences, VLDL, very low density lipoprotein, Cell Line, Tumor, MPH, mouse primary hepatocyte, medicine, TMA, tissue microarray, Animals, Humans, ddc:612, neoplasms, AUBPs, AUBP, adenylate-uridylate-rich element binding protein, EV, empty vector, Hepatology, business.industry, Cancer, DMEM, Dulbecco modified Eagle medium, Oncogenes, medicine.disease, Survival Analysis, 030104 developmental biology, Hepatocyte nuclear factor 4 alpha, siRNA, small interfering RNA, Cancer cell, Cancer research, Hepatocytes, FCS, fetal calf serum, NAFLD, nonalcoholic fatty liver disease, business, HCC, hepatocellular carcinoma, SD, standard deviation, DEN, diethylnitrosamine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e04acdfadc7dd7cf24b47a30be60cc1aTest
https://pubmed.ncbi.nlm.nih.gov/32987153Test

المؤلفون: Paul A. Dawson, Courtney B. Ferrebee

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 5, Iss 2, Pp 129-134 (2015)

مصطلحات موضوعية: HNF4α, hepatocyte nuclear factor 4 alpha, OATP, organic anion transporting polypeptide, PPAR, peroxisome proliferator-activated receptor, Review, Intestinal absorption, G6Pase, glucose-6-phosphatase, LDL, low density lipoprotein, SREBP1c, sterol regulatory element binding protein-1c, DIO2, deiodinase 2, SHP, small heterodimer partner, NTCP, Na+-taurocholate transporting polypeptide, OST, organic solute transporter, Glucose homeostasis, General Pharmacology, Toxicology and Pharmaceutics, Enterohepatic circulation, FGFR4, fibroblast growth factor receptor 4, Bile acid, ACCII, acetyl-CoA carboxylase 2, G protein-coupled bile acid receptor, FAS, fatty acid synthase, Intestine, Transporters, GLP-1, glucagon-like polypeptide-1, Biochemistry, Liver, Cell signaling, medicine.drug_class, FXR, farnesoid X-receptor, TGR5, G-protein-coupled bile acid receptor, Biology, Cholesterol 7 alpha-hydroxylase, FOXO1, forkhead box protein O1, digestive system, PGC1α, peroxisome proliferator-activated receptor gamma coactivator 1 alpha, VLDL, very low density lipoprotein, IBABP, ileal bile acid binding protein, medicine, T4, thyroid hormone, BSEP, bile salt export pump, lcsh:RM1-950, Lipid metabolism, CYP7A1, cholesterol 7α-hydroxylase, Bile acids, FGF, fibroblast growth factor, lcsh:Therapeutics. Pharmacology, APO, apolipoproteins, PEPCK, phosphoenolpyruvate carboxykinase, Energy homeostasis, ASBT, apical sodium-dependent bile acid transporter

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30b1cfbf65891d85d42c0256c8af457Test

المؤلفون: Yoshinori, Arisaka, Jun, Kobayashi, Kazuo, Ohashi, Kohei, Tatsumi, Kyungsook, Kim, Yoshikatsu, Akiyama, Masayuki, Yamato, Teruo, Okano

المصدر: Regenerative Therapy

مصطلحات موضوعية: Alb, albumin, IPAAm, N-isopropylacrylamide, F7, coagulation factor VII, CIPAAm, 2-carboxyisopropylacrylamide, TCPS, tissue culture polystyrene dishe, PBS, Dulbecco's phosphate buffered saline, bFGF, basic fibroblast growth factor, RT-PCR, reverse transcription polymerase chain reaction, FBS, fetal bovine serum, IC, poly(N-isopropylacrylamide-co-2-carboxyisopropylacrylamide) on TCPS, Poly(N-isopropylacrylamide), EDC, 1-ethyl-3-(3-dimetylaminopropyl)-carbodiimide hydrochloride, EGF, epidermal growth factor, DMEM, Dulbecco's modified Eagle's medium, EDTA, trypsin/ethylenediaminetetraacetic acid, HB-EGFX/heparin-IC, HB-EGF-bound heparin-IC, Heparin, MES, morpholinoethanesulfonic acid monohydrate, ELISA, enzyme-linked immunosorbent assay, NHS, N-hydroxysuccinimide, heparin-IC, heparin-modified IC, ECM, extracellular matrix, Hnf4α, hepatocyte nuclear factor 4 alpha, F9, coagulation factor IX, Thermoresponsive cell culture surface, HB-EGF, heparin-binding EGF-like growth factor, Hepatocyte sheet, PIPAAm + HB-EGFY, PIPAAm with soluble HB-EGF, Original Article, Heparin-binding EGF-like growth factor, PIPAAm, poly(N-isopropylacrylamide) on TCPS, hormones, hormone substitutes, and hormone antagonists

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::1d671892cbea01dc8627499e3a8e21d0Test
https://pubmed.ncbi.nlm.nih.gov/31245479Test

المؤلفون: Anna, Baghdasaryan, Peter, Chiba, Michael, Trauner

المصدر: Molecular Aspects of Medicine

مصطلحات موضوعية: PGC-1α, peroxisome proliferator-activated receptor gamma coactivator-1 alpha, FXR, farnesoid X receptor (NR1H4), HNF4α, hepatocyte nuclear factor 4 alpha, CARM1, co-activator-associated arginine methyltransferase 1, OATP, organic anion transporting polypeptide, VDR (NR1I1), vitamin D receptor, Review, BCRP (ABCG2), breast cancer resistance protein, NDRG2, NMYC downstrean-regulated gene 2, MRP4 (ABCC4), multidrug resistance-associated protein 4, SRC2, steroid receptor co-activator 2, GGT, gamma-glutamyl transpeptidase, MDR1 (ABCB1), multidrug resistance protein 1, Nuclear receptors, GRE, glucocorticoid response element, CtBP, C-terminal binding protein, GCA, glycocholic acid, TβMCA, β-tauromuricholic acid, TNF-α, tumor necrosis factor alpha, ATB-binding cassette transporters, FGF19/FGF15, fibroblast growth factor 19/15, MARE, MAF recognition element, ATP Binding Cassette Transporter, Subfamily B, Member 11, TCDCA, taurochenodeoxycholic acid, CA, cholic acid, Cholestasis, ASBT (SLC10A2), apical sodium-dependent bile acid transporter, Symporters, AE2 (SLC4A2), anion exchanger 2, ABC, ATP-binding cassette, FXRE, FXR response element, cAMP, cyclic adenosine monophosphate, DILI, drug-induced liver injury, IL-6, interleukin 6, PL, phospholipid, TGR5, G protein coupled bile acid receptor, OCA, obeticholic acid, OSTα/OSTβ (SLC51A/SLC51B), organic solute transporter alpha/beta, LRH1 (NR5A2), liver receptor homologue 1, JNK, c-Jun N-terminal kinase, NRF2, nuclear factor erythroid 2-related factor 2, LPS, lipopolysaccharide, BRIC2, benign recurrent intrahepatic cholestasis type 2, LXR (NR1H3), liver X receptor, Transcriptional Activation, PFIC2, progressive familial intrahepatic cholestasis type 2, PXR (NR1I2), pregnane X receptor, TCA, taurocholic acid, RXRα (NR2B1), retinoid X receptor, Organic Anion Transporters, Sodium-Dependent, CCl4, carbone tetrachloride, UDCA, ursodeoxycholic acid, Bile Acids and Salts, CDCA, chenodeoxycholic acid, STAT-5, signal transducer and activator of transcription 5, LCA, litocholic acid, ALT, alanine aminotransferase, CBDL, common bile duct ligation, IR-1, inverse repeat 1, TUDCA, tauroursodeoxycholic acid, Humans, ICP, intrahepatic cholestasis of pregnancy, GR (NR3C1), glucocorticoid receptor, MRP2 (ABCC2), multidrug resistance-associated protein 2, TαMCA, α-tauromuricholic acid, TPN, total parenteral nutrition, ALP, alkaline phosphatase, IL-1β, interleukin-1 beta, SREBP1, sterol regulatory element-binding protein 1, Membrane Transport Proteins, Biological Transport, BSEP (ABCB11), bile salt export pump, MAF, musculo-aponeurotic fibrosacroma, ASCOM, activating signal cointegrator-2-containing complex, HNF1α, hepatocyte nuclear factor 1 alpha, MCL-1, myeloid cell leukemia factor 1, NTCP (SLC10A1), Na+-taurocholate cotransporting polypeptide solute carrier family 10 member 1, VPAC-1, vasoactive intestinal polypeptide activated receptor, AMPK, AMP-activated protein kinase, MRP3 (ABCC3), multidrug resistance-associated protein 3, NF-κB, nuclear factor kappa-B, PSC, primary sclerosing cholangitis, Gene Expression Regulation, DCA, deoxycholic acid, BS, bile salt, MDR2 (ABCB4), multidrug resistance protein 2, PPARα (NR1C1), peroxisome proliferator-activated receptor alpha, SHP (NR0B2), short heterodimer partner, RARα (NR1B1), retinoic acid receptor, ATP-Binding Cassette Transporters, PBC, primary biliary cirrhosis, PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::02c2316b6e5fe1c1e107f32e273f6aebTest
https://pubmed.ncbi.nlm.nih.gov/24333169Test