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المؤلفون: David A. Frank, Isidora Tošić
المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1167-1178 (2021)مصطلحات موضوعية: Cancer Research, p53, tumor protein 53, MEF2D, Myocyte Enhancer Factor 2D, FASN, fatty acid synthase, OXPHOS, oxidative phosphorylation, ERH, enhancer of rudimentary homolog, PDGF, platelet-derived growth factor, PFK, phosphofructokinase, CREB, cyclic AMP response element-binding protein, HDL-C, high-density lipoprotein cholesterol, chemistry.chemical_compound, PC, phosphatidylcholine, GRIM-19, gene associated with retinoid-IFN-induced mortality, Neoplasms, Transcriptional regulation, TGFβ, transforming growth factor beta, AML, acute myeloid leukemia, RC254-282, CDK, cyclin-dependent kinase, FABP6, fatty acid binding protein 6, BCL, B-cell lymphoma, CLL, chronic lymphocytic leukemia, Chemistry, LIF, leukemia inhibitory factor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, VEGF, vascular endothelial growth factor, FBP1, fructose-bisphosphatase 1, GPI, glucose-6-phosphate isomerase, Cell biology, MMP, matrix metalloproteinase, STAT, signal transducer and activator of transcription, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, GP130, glycoprotein 130, Phosphorylation, NHL, non-Hodgkin's lymphoma, JAK, Janus kinase, Adenosine triphosphate, CNTF, ciliary neurotrophic factor, STAT3 Transcription Factor, ATP, adenosine triphosphate, TAG, triacylglycerol, Protein processing, Post-translational, PPARγ, peroxisome proliferator-activated receptor gamma, ETC, electron transport chain, TNFα, tumor necrosis factor alpha, RIME, rapid immunoprecipitation mass spectrometry of endogenous proteins, GLUT1, glucose transporter 1, PGK1, phosphoglycerate kinase, MPTP, mitochondrial permeability transition pore, Mediator, Review article, CML, chronic myeloid leukemia, HIF1α, hypoxia inducible factor 1α, PIAS, protein inhibitors of activated STATs, SOCS, suppressors of cytokine signaling, Animals, Humans, IFN, interferon, LDHA, lactate dehydrogenase A, Transcription factor, PKCδ, protein kinase C δ, TF, transcription factors, EGF, epidermal growth factor, SM, sphingomyelin, SREBP1, sterol regulatory element-binding protein 1, IAP, inhibitor of apoptosis, PTP, protein tyrosine phosphatases, Tyrosine phosphorylation, Lipid metabolism, BCSC, breast cancer stem cells, IL, interleukin, Metabolism, OSM, oncostatin M, Anaerobic glycolysis, NFκB, nuclear factor kappa B, TBK1, TANK-binding kinase 1, MCL, myeloid cell leukemia, LDL-C, low-density lipoprotein cholesterol, PBP, PPARγ binding protein, CPT1B, carnitine palmitoyltransferase 1B, FAO, fatty acid oxidation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95fc1e221705a2edcb47149735290583Test
http://europepmc.org/articles/PMC8569436Test -
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المؤلفون: Dae-Kyu Song, Seung Soon Im, Jae-Hoon Bae, Hyun-Woo Cho, Su-Kyung Shin, Seung-Eun Song
المصدر: Redox Biology
Redox Biology, Vol 37, Iss, Pp 101749-(2020)مصطلحات موضوعية: AMPK, AICAR, 5-aminoimidazole-4-carboxamide ribonucleotide, ATP5A, ATP synthase alpha-subunit gene, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, SREBP, sterol regulatory element-binding protein, White adipose tissue, Biochemistry, G6PD, glucose-6-phosphate dehydrogenase, GATA2, GATA-binding protein 2, C/EBP, CCAAT/enhancer-binding protein, Mice, 0302 clinical medicine, Mcad, medium-chain acyl-CoA dehydrogenase, lcsh:QH301-705.5, Adipogenesis, MTCO1, mitochondrially encoded cytochrome C oxidase I, SDHB, succinate dehydrogenase complex iron sulfur subunit B, NOX4, UQCRC, ubiquinol-cytochrome C reductase core protein 2, TG, triglycerides, FAS, fatty acid synthase, SDH, succinate dehydrogenase, qPCR, quantitative polymerase chain reaction, lcsh:Medicine (General), Nicotinamide adenine dinucleotide phosphate, medicine.medical_specialty, IDH, isocitrate dehydrogenase, ORO, Oil Red O, SEM, standard error of the mean, Diet, High-Fat, 03 medical and health sciences, CKO, catalase-knockout, HIF1α, hypoxia-inducible factor 1α, MDH, malate dehydrogenase, Hydrogen Peroxide, Hypertrophy, Fibroblasts, MEF, mouse embryonic fibroblast, WT, wild-type, White adipocyte, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, chemistry, siRNA, small interfering RNA, Acox1, acyl-CoA oxidase 1, 030217 neurology & neurosurgery, Cs, citrate synthase, 0301 basic medicine, PASMC, pulmonary artery smooth muscle cells, HFD, high-fat diet, Clinical Biochemistry, Adipocytes, White, Fgf21, fibroblast growth factor 21, medicine.disease_cause, chemistry.chemical_compound, lcsh:R5-920, biology, TFAM, mitochondrial transcription factor A, WAT, white adipose tissue, Catalase, NOX, NADPH oxidase, Lipogenesis, ND, normal chow diet, siCAT, catalase-siRNA, Research Paper, OXPHOS, total oxidative phosphorylation system, ETC, electron transport chain, PBS, phosphate-buffered saline, TCA, tricarboxylic acid, PPP, pentose phosphate pathway, PGC1α, PPARγ coactivator 1-α, NRF1, nuclear respiratory factor 1, DMEM, Dulbecco's Modified Eagle Medium, FER, food efficiency ratio, ROS, reactive oxygen species, FBS, fetal bovine serum, Internal medicine, 3T3-L1 Cells, Pref-1, preadipocyte factor 1, medicine, Animals, Obesity, NDUFB8, NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial, Hyperplasia, Organic Chemistry, Lcad, long-chain acyl-CoA dehydrogenases, PPARγ, peroxisome proliferator-activated receptor γ, AMPK, AMP-activated protein kinase, Oxidative Stress, CPT, carnitine palmitoyltransferase, lcsh:Biology (General), AMP, adenosine monophosphate, NAC, N-acetyl cysteine, biology.protein, H&E, hematoxylin and eosin, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94510a67d93a163b83be3457a2703930Test
http://europepmc.org/articles/PMC7575809Test -
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المؤلفون: Lars Stechemesser, Eva Rohde, Wolfgang Patsch, Simon Auer, Daniel Weghuber, Elmar Aigner, Elisabeth Haschke-Becher, Stephan Zandanell, Bernhard Paulweber, Thomas K. Felder, Sebastian K. Eder, David Niederseer, Andrej Wagner, Alexandra Feldman, Ursula Huber-Schönauer, Michael Strasser, Christian Datz, Sandra Ruhaltinger, Christoph Grabmer
المساهمون: University of Zurich, Aigner, Elmar
المصدر: Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 1, Pp 38-47 (2017)مصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, BMI, body mass index, AST, aspartate aminotransferase, Type 2 diabetes, 1307 Cell Biology, PC, phosphatidylcholine, IR, insulin resistance, HOMA-IR, homeostatic model assessment-insulin resistance, GGT, gamma-glutamyl transpeptidase, Homeostasis, Iron overload, Glucose homeostasis, PC_E, plasmalogens, Metabolic Syndrome, TNF, tumor necrosis factor, biology, PEMT, phosphatidylethanolamine N-methyltransferase, Middle Aged, DIOS, dysmetabolic iron overload syndrome, HDL, high density lipoproteins, 10209 Clinic for Cardiology, CRP, C-reactive protein, Female, Original Article, MetS, metabolic syndrome, −Fe, without iron overload, Adult, Akt/PKB, Akt/protein kinase B, lcsh:Internal medicine, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, GNMT, glycine N-methyltransferase, Iron, 610 Medicine & health, GLUT1, glucose transporter 1, Carbohydrate metabolism, WHO, World Health Organization, LDL, low density lipoproteins, 03 medical and health sciences, Insulin resistance, GSK3β, glycogen synthase kinase 3β, ALT, alanine aminotransferase, VLDL, very low-densitylipoproteins, Internal medicine, T2D, type 2 diabetes mellitus, 1312 Molecular Biology, medicine, Humans, Metabolomics, Obesity, lcsh:RC31-1245, Molecular Biology, HIF1α, hypoxia-inducible factor 1α, RBC, red blood count, CDP, Cytidinediphosphat, MRI, magnet resonance imaging, +Fe, with iron overload, FoxO1, forkhead transcription factor O1, Sarcosine, Cell Biology, Glucose Tolerance Test, Phlebotomy, medicine.disease, WHR, waist hip ratio, IL, interleukin, Ferritin, Cross-Sectional Studies, Glucose, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, Ferritins, biology.protein, Citrulline, GLUT1, Hyperferritinemia, Insulin Resistance, Metabolic syndrome, PCOS, polycystic ovary syndrome, oGTT, oral glucose tolerance test
وصف الملف: 1-s2.0-S2212877816302095-main.pdf - application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae81e4d845b080c0c9735c73057cb1b6Test
https://doi.org/10.1016/j.molmet.2016.10.006Test -
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المؤلفون: Axel Knebel, Lorna Plater, Christoph H. Emmerich, Sam Strickson, Natalia Shpiro, Philip Cohen, David G. Campbell, Maria Stella Ritorto
المصدر: Biochemical Journal
مصطلحات موضوعية: Lipopolysaccharides, Ubiquitin-conjugating enzyme, Biochemistry, DMEM, Dulbecco’s modified Eagle’s medium, Mice, linear ubiquitin assembly complex (LUBAC), K63-pUb, Lys63-linked polyubiquitin, NF-KappaB Inhibitor alpha, Ubiquitin, MS/MS, tandem MS, nuclear factor κB (NF-κB), pUb, polyubiquitin, TRAF, tumour-necrosis-factor-receptor-associated factor, Sulfones, RBR, RING-between-RING, TAB, TAK1-binding protein, IKK, IκB kinase, IκB, inhibitor of NF-κB, GFP, green fluorescent protein, HOIP, haem-oxidized IRP2 ligase-1-interacting protein, NEMO, NF-κB essential modifier, K48-pUb, Lys48-linked polyubiquitin, biology, LUBAC, linear ubiquitin assembly complex, Kinase, NEDD8, neural-precursor-cell-expressed developmentally down-regulated 8, Ubiquitin ligase, HRMS, high-resolution mass spectra, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, TBK1, tumour-necrosis-factor-receptor-associated factor-associated NF-κB activator-binding kinase 1, JNK, c-Jun N-terminal kinase, LPS, lipopolysaccharide, Phosphorylation, I-kappa B Proteins, ubiquitin conjugating 13 (Ubc13), NF-κB, nuclear factor κB, DLBCL, diffuse large B-cell lymphoma, PAMP, pathogen-associated molecular pattern, Signal Transduction, Research Article, Proteasome Endopeptidase Complex, Molecular Sequence Data, lymphoma, MALDI–TOF, matrix-assisted laser-desorption ionization–time-of-flight, ERK, extracellular-signal-regulated kinase, HEK, human embryonic kidney, Ubc, ubiquitin conjugating, Cell Line, Tumor, Nitriles, MyD88, myeloid differentiation factor 88, Animals, Humans, Amino Acid Sequence, Molecular Biology, HIF1α, hypoxia-inducible factor 1α, IL-1R, IL-1 receptor, HTLV-1, human T-cell lymphotropic virus 1, Macrophages, HEK 293 cells, Ubiquitination, NF-kappa B p50 Subunit, Receptors, Interleukin-1, myeloid differentiation factor 88 (MyD88), TAK1, transforming growth factor β-activated kinase 1, Cell Biology, Hypoxia-Inducible Factor 1, alpha Subunit, Molecular biology, IL, interleukin, UBE, ubiquitin-activating enzyme, IκBα, proteasome, Gene Expression Regulation, Proteasome, IRAK, IL-receptor-associated kinase, Myeloid Differentiation Factor 88, Ubiquitin-Conjugating Enzymes, biology.protein, MAPK, mitogen-activated protein kinase, Interleukin-1, DAPI, 4′,6-diamidino-2-phenylindole
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af6008194e741619655a2e05fd75147Test
https://doi.org/10.1042/bj20121651Test -
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المصدر: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 14, Iss C, Pp 223-233 (2016)مصطلحات موضوعية: 0301 basic medicine, TFs, transcription factors, PSAT, phosphoserine aminotransferase, Metabolic network, ACC, acetyl-CoA carboxylase, BRCA1, breast cancer type 1 susceptibility protein, Biochemistry, G6PD, glucose-6-phosphate dehydrogenase, PFK, phosphofructokinase, Serine, PC, pyruvate carboxylase, 0302 clinical medicine, GLS, glutaminase, Structural Biology, FH, fumarate hydratase, PSPH, phosphoserine phosphatase, Cancer, Genetics, p53, tumor protein p53, MicroRNA, SHMT, serine hydroxymethyl transferase, FAS, fatty acid synthase, ME, malic enzyme, Computer Science Applications, Cell biology, GLUT, glucose transporter, ACL, ATP-citrate lyase, PGK, phosphoglycerate kinase (PGK), MCT, monocarboxylic acid transporter, 030220 oncology & carcinogenesis, SDH, succinate dehydrogenase, Biotechnology, lcsh:Biotechnology, PHGDH, phosphoglycerate dehydrogenase, Biophysics, TCA, tricarboxylic acid, GDH, glutamate dehydrogenase, IDH, isocitrate dehydrogenase, PPP, pentose phosphate pathway, Biology, 03 medical and health sciences, lcsh:TP248.13-248.65, HIF1α, hypoxia inducible factor 1α, microRNA, Transcription factor, Gene, SREBP1, sterol regulatory element binding protein 1, Oncogene, Transcriptional regulation network, PEP, phosphoenolpyruvate, HK, hexokinase, PKM, muscle-pyruvate kinase, PDH, pyruvate dehydrogenase, Sterol regulatory element-binding protein, 030104 developmental biology, 2-HG, 2-hydroxyglutarate, Metabolism, Anaerobic glycolysis, Sterol Regulatory Element Binding Protein 1, PEPCK, phosphoenolpyruvate carboxykinase, Short Survey, c-MYC, V-myc avian myelocytomatosis viral oncogene homolog, miR/miRNA, LDH, lactate dehydrogenase micro RNA, PDK, pyruvate dehydrogenase kinase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::268eb25358d62f10bdd206de1d1c97d9Test
https://pubmed.ncbi.nlm.nih.gov/27358718Test -
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المؤلفون: Alberto Smith, Katherine Mattock, Matthew Waltham, Prakash Saha, Colin E. Evans, Bijan Modarai, Julia Humphries, kevin Burnand, H. Anwar Ahmad, Ashish Patel, Ashar Wadoodi
المصدر: Thrombosis Research
مصطلحات موضوعية: Male, Vascular Endothelial Growth Factor A, Time Factors, L-mim, L-mimosine, Procollagen-Proline Dioxygenase, Neovascularization, Physiologic, Vena Cava, Inferior, Biology, Pregnancy Proteins, Hypoxia-inducible factor, Inferior vena cava, chemistry.chemical_compound, Hypoxia-Inducible Factor 1-Alpha, Mice, IVC, inferior vena cava, medicine, Animals, Mimosine, Thrombus, Enzyme Inhibitors, Hypoxia, HIF1α, hypoxia-inducible factor 1α, Placenta Growth Factor, Venous Thrombosis, Mice, Inbred BALB C, Regular Article, PLGF, placental growth factor, Hematology, medicine.disease, Hypoxia-Inducible Factor 1, alpha Subunit, Thrombosis, VEGF, vascular endothelial growth factor, Up-Regulation, Vascular endothelial growth factor, Venous thrombosis, Vascular endothelial growth factor A, Disease Models, Animal, chemistry, Hypoxia-inducible factors, medicine.vein, Thrombus resolution, Immunology, Cancer research, cardiovascular system, Angiogenesis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74334a45454174dd9ffddff6f4e4ea4fTest
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المؤلفون: Martina Calore, Leon J. De Windt
المساهمون: Cardiologie, RS: CARIM - R2 - Cardiac function and failure
المصدر: Journal of the American College of Cardiology, 66(18), 2016-2018. Elsevier Science
Journal of the American College of Cardiologyمصطلحات موضوعية: mRNA, messenger ribonucleic acid, miRNA, micro–ribonucleic acid, heart failure, STREAMS, 030204 cardiovascular system & hematology, Ancient history, 03 medical and health sciences, angiogenesis, 0302 clinical medicine, lncRNA, siRNA, small interfering ribonucleic acid, HUVEC, human umbilical vein endothelial cell, miR, mature micro–ribonucleic acid, Medicine, Humans, endothelial cell biology, long noncoding RNA, HIF1α, hypoxia-inducible factor 1α, 030304 developmental biology, Original Investigation, GFP, green fluorescent protein, 0303 health sciences, Neovascularization, Pathologic, business.industry, hypoxia, EC, endothelial cell, lncRNA, long noncoding ribonucleic acid, Cell hypoxia, Hypoxia-Inducible Factor 1, alpha Subunit, EHT, engineered heart tissue, VEGF, vascular endothelial growth factor, 6. Clean water, Cell Hypoxia, RNA-seq, ribonucleic acid sequencing, lincRNA, long intergenic noncoding ribonucleic acid, RNA, ribonucleic acid, RNA Interference, RNA, Long Noncoding, Cardiology and Cardiovascular Medicine, Greek mythology, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b98a7ddb99ed8a075ba92938d57830Test