Acute immunologic and metabolic responses of beef heifers following topical administration of flunixin meglumine at various times relative to bovine herpesvirus 1 and
التفاصيل البيبلوغرافية
العنوان:
Acute immunologic and metabolic responses of beef heifers following topical administration of flunixin meglumine at various times relative to bovine herpesvirus 1 and
To quantify acute immunologic and metabolic responses of beef heifers following topical administration of transdermal flunixin meglumine (TDFM) at various times relative to bovine herpesvirus 1 (BHV1) and32 beef heifers (mean body weight, 170 kg).Heifers were assigned to 1 of 4 groups. Heifers in the control group did not receive TDFM, whereas 1 dose of TDFM (3.3 mg/kg) was topically applied to heifers of groups A, V, and B at -144, -72, and 0 hours. All heifers were inoculated with 1 × 10Mean vaginal temperature was similar between group A and the control group. Mean vaginal temperatures for groups V and B were generally lower than that for the control group following BHV1 andResults suggested that topical administration of TDFM to beef cattle effectively alleviated pyrexia without adverse effects on acute immunologic or metabolic responses when TDFM was administered at the same time as, but not before, respiratory pathogen challenge.