المؤلفون: Salazar, Jairo, Poejo, Joana, Mata, Ana M., Samhan Arias, Alejandro Khalil, Gutierrez-Merino, Carlos

المساهمون: UAM. Departamento de Bioquímica

مصطلحات موضوعية: Amyloid β, calmodulin, calbindin-D28k, antagonist peptide, Alzheimer’s disease, fluorescence, docking, Medicina

وصف الملف: application/pdf

العلاقة: International Journal of Molecular Sciences; https://doi.org/10.3390/ijms23042289Test; Gobierno de España. BFU2017-85723-P; International Journal of Molecular Sciences 23.4 (2022): 2289; 1422-0067 (online); 1661-6596 (print); http://hdl.handle.net/10486/712065Test; 2289-1; 2289-22; 23

الإتاحة: https://doi.org/10.3390/ijms23042289Test
http://hdl.handle.net/10486/712065Test

المؤلفون: Gorospe, Berta, Moura, José J.G., Gutierrez-Merino, Carlos, Samhan Arias, Alejandro Khalil

المساهمون: UAM. Departamento de Bioquímica

مصطلحات موضوعية: caveolin-1, caveolin-2, cholesterol, membrane interaction, secondary structure prediction, Medicina

وصف الملف: application/pdf

العلاقة: International Journal of Molecular Sciences; https://doi.org/10.3390/ijms232315203Test; International Journal of Molecular Sciences 23.23 (2022): 15203; 1661-6596 (print); 1422-0067 (online); http://hdl.handle.net/10486/711203Test; 15203-1; 23; 15203-18

الإتاحة: https://doi.org/10.3390/ijms232315203Test
http://hdl.handle.net/10486/711203Test

المؤلفون: Berrocal Carrillo, María, Corbacho Cuello, Isaac, Gutiérrez Merino, Carlos, Mata Durán, Ana María

العلاقة: https://www.sciencedirect.com/science/article/pii/S0028390818303691Test

الوصول الحر: http://hdl.handle.net/10662/19085Test

المؤلفون: Poejo, Joana Margarida de Andrade, Berrocal Carrillo, María, Sáez Mansilla, Lucía, Gutiérrez Merino, Carlos, Mata Durán, Ana María

المساهمون: N/A, Universidad de Extremadura. Departamento de Biología Vegetal, Ecología y Ciencias de la Tierra

مصطلحات موضوعية: A1 astrocitos, Componente del complemento C3, Amiloide β, Calcio citosólico, Homeostasis del calcio intracelular, Entrada de calcio operada por almacén, Bomba de calcio de la membrana plasmática, A1 astrocytes, Complement component C3, Amyloid, Cytosolic calcium, Intracellular calcium homeostasis, Store-operated calcium entry, Plasma membrane calcium pump, 2302 Bioquímica

وصف الملف: 16 p.; application/pdf

العلاقة: https://www.mdpi.com/1420-3049/28/14/5363Test; https://doi.org/10.3390/molecules28145363Test; http://hdl.handle.net/10662/19051Test; Poejo J, Berrocal M, Saez L, Gutierrez-Merino C, Mata AM. (2023). Store-Operated Calcium Entry Inhibition and Plasma Membrane Calcium Pump Upregulation Contribute to the Maintenance of Resting Cytosolic Calcium Concentration in A1-like Astrocytes. Molecules; 28(14):5363. https://doi.org/10.3390/molecules28145363Test; Molecules; 14; 5363-1; 5363-16; 28; orcid:0000-0003-3673-7007; orcid:0000-0002-2887-7854

الإتاحة: https://doi.org/10.3390/molecules28145363Test
http://hdl.handle.net/10662/19051Test

المؤلفون: Salazar, Jairo, Samhan-Arias, Alejandro K., Gutiérrez-Merino, Carlos

المساهمون: Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), European Commission, Fundación Carolina

مصطلحات موضوعية: Amyloid β(1–42), Amyloid β(25–35), Hexa-histidine, Calmodulin, Calbindin-D28k, Hexa-histidine-tag, Recombinant cytochrome b5 reductase, Fluorescence, Fluorescence resonance energy transfer

وصف الملف: application/pdf

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/BFU2017-85723-P/ES/PROTEINAS DE SEÑALIZACION DEL CALCIO NEURONAL MODULADAS POR CALMODULINA COMO DIANAS PARA LA BUSQUEDA DE NUEVOS ANTAGONISTAS DEL PEPTIDO BETA-AMILOIDE EN EL ALZHEIMER/; Publisher's version; The underlying dataset has been published as supplementary material of the article in the publisher platform at 10.3390/molecules28207138; https://doi.org/10.3390/molecules28207138Test; Sí; Molecules 28(20): 7138 (2023); http://hdl.handle.net/10261/349642Test; http://dx.doi.org/10.13039/501100000780Test; http://dx.doi.org/10.13039/501100011033Test

الإتاحة: https://doi.org/10.3390/molecules28207138Test
https://doi.org/10.13039/501100000780Test
https://doi.org/10.13039/501100011033Test
http://hdl.handle.net/10261/349642Test

المؤلفون: Samhan-Arias, Alejandro K., Poejo, Joana, Marques-da-Silva, Dorinda, Martínez-Costa, Oscar H., Gutiérrez-Merino, Carlos

مصطلحات موضوعية: Flotillin, Caveolin, Ganglioside, Lipid rafts, Lipid membrane domains, Calcium channel, NMDA, PMCA, P2XR, Membrane domains, Neuron, Brain

وصف الملف: application/pdf

العلاقة: Publisher's version; http://dx.doi.org/10.3390/molecules28237909Test; Sí; e-issn: 1420-3049; Molecules 28(23): 7909 (2023); http://hdl.handle.net/10261/349382Test

الإتاحة: https://doi.org/10.3390/molecules28237909Test
http://hdl.handle.net/10261/349382Test

المؤلفون: López Sánchez, Carmen, Poejo, Joana Margarida de Andrade, García López, Virginio, Salazar Casco, Jairo, García Martínez, Virginio Enrique, Gutiérrez Merino, Carlos

المساهمون: Universidad de Extremadura. Instituto universitario de Biomarcadores de Patologías Metabólicas y Moleculares (IBPM), Universidad de Extremadura. Departamento de Anatomía, Biología Celular y Zoología, Universidad de Extremadura. Departamento de Bioquímica, Biología Molecular y Genética, Universidad Nacional Autónoma de Nicaragua

مصطلحات موضوعية: Kaempferol, Ácido 3-nitropropiónico, Ratas Wistar, Proteína C3, Astrocitos reactivos A1, Péptidos β amiloides, 3-Nitropropionic acid, Wistar rats, C3 protein, Reactive A1 astrocytes, Amyloid β peptides, 2302 Bioquímica

وصف الملف: 13 p.; application/pdf

العلاقة: https://doi.org/10.1016/j.fct.2022.113017Test; http://hdl.handle.net/10662/17229Test; Lopez-Sanchez, C.; Poejo, J.; Garcia-Lopez, V.; Salazar, J.; Garcia-Martinez, V.; Gutierrez-Merino, C. (2022). Kaempferol prevents the activation of complement C3 protein and the generation of reactive A1 astrocytes that mediate rat brain degeneration induced by 3-nitropropionic acid, Food and Chemical Toxicology, Volume 164, 113017, ISSN 0278-6915, https://doi.org/10.1016/j.fct.2022.113017Test; Food and Chemical Toxicology; 113017-1; 113017-13; 164; orcid:0000-0001-8740-1074; orcid:0000-0002-7760-1985; orcid:0000-0003-3673-7007

الإتاحة: https://doi.org/10.1016/j.fct.2022.113017Test
http://hdl.handle.net/10662/17229Test

المؤلفون: Poejo, Joana Margarida de Andrade, Orantos Aguilera, Yolanda, Martín Romero, Francisco Javier, Mata Durán, Ana María, Gutiérrez Merino, Carlos

المساهمون: Universidad de Extremadura. Departamento de Bioquímica, Biología Molecular y Genética

مصطلحات موضوعية: Amiloide-β (1-42), Entrada de calcio operada por almacenamiento, STIM1, Calmodulina, Retículo endoplásmico, Células HT-22, Enfermedad de Alzheimer, Amyloid-β (1-42), Store-operated calcium entry, Calmodulin, Endoplasmic reticulum, HT-22 cells, Alzheimer’s disease, 2302 Bioquímica

وصف الملف: 34 p.; application/pdf

العلاقة: https://doi.org/10.3390/ijms232012678Test; https://www.mdpi.com/1422-0067/23/20/12678Test; http://hdl.handle.net/10662/19059Test; Poejo J, Orantos-Aguilera Y, Martin-Romero FJ, Mata AM, Gutierrez-Merino C. (2022). Internalized Amyloid-β (1-42) Peptide Inhibits the Store-Operated Calcium Entry in HT-22 Cells. International Journal of Molecular Sciences; 23(20):12678. https://doi.org/10.3390/ijms232012678Test; International Journal of Molecular Sciences; 20; 12678-1; 12678-34; 23; orcid:0000-0001-8740-1074; orcid:0000-0003-3742-2488; orcid:0000-0001-6796-7396; orcid:0000-0002-2887-7854; orcid:0000-0003-3673-7007

الإتاحة: https://doi.org/10.3390/ijms232012678Test
http://hdl.handle.net/10662/19059Test

المؤلفون: Aureliano, Manuel, Fraqueza, Gil, Berrocal, Maria, Cordoba-Granados, Juan J., Gumerova, Nadiia I., Rompel, Annette, Gutierrez-Merino, Carlos, Mata, Ana M.

مصطلحات موضوعية: Polyoxometalates, Polyoxometalate?s stability, Ca2+-ATPase, ATPases inhibitors, Anticancer drugs, Drug discovery

العلاقة: info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04326%2F2020/PT; http://hdl.handle.net/10400.1/18943Test

الإتاحة: https://doi.org/10.1016/j.jinorgbio.2022.111952Test
http://hdl.handle.net/10400.1/18943Test

المؤلفون: Gorospe, Berta, Moura, José J. G., Gutierrez-Merino, Carlos, Samhan-Arias, Alejandro K.

المساهمون: DQ - Departamento de Química, LAQV@REQUIMTE

مصطلحات موضوعية: caveolin-1, caveolin-2, cholesterol, membrane interaction, secondary structure prediction, Catalysis, Molecular Biology, Spectroscopy, Computer Science Applications, Physical and Theoretical Chemistry, Organic Chemistry, Inorganic Chemistry

العلاقة: Funding Information: info:eu-repo/grantAgreement/FCT/OE/SFRH%2FBPD%2F100069%2F2014/PT; info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04378%2F2020/PT; info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50006%2F2020/PT; Gorospe, B., Moura, J. J. G., Gutierrez-Merino, C., & Samhan-Arias, A. K. (2022). Biochemical and Biophysical Characterization of the Caveolin-2 Interaction with Membranes and Analysis of the Protein Structural Alteration by the Presence of Cholesterol. International Journal of Molecular Sciences, 23(23), [15203]. https://doi.org/10.3390/ijms232315203Test; PURE: 55548660; PURE UUID: 918283af-83ba-4a4c-8a86-b0c3e3b09497; Scopus: 85143651321; PubMed: 36499524; PubMedCentral: PMC9736327; WOS: 000896141500001; ORCID: /0000-0002-4726-2388/work/130766159; http://hdl.handle.net/10362/150485Test; https://doi.org/10.3390/ijms232315203Test

الإتاحة: https://doi.org/10.3390/ijms232315203Test
http://hdl.handle.net/10362/150485Test