المؤلفون: Baur, J. A., Chen, D., Chini, E. N., Chua, K., Cohen, H. Y., de Cabo, R., Deng, C., Dimmeler, S., Gius, D., Helfand, S. L., Imai, S.-I., Itoh, H., Kadowaki, T., Koya, D., Leeuwenburgh, C., McBurney, M., Nabeshima, Y.-I., Neri, C., Oberdoerffer, P., Pestell, R. G., Rogina, B., Sadoshima, J., Sartorelli, V., Serrano, M., Sinclair, D. A., Steegborn, C., Tatar, M., Tissenbaum, H. A., Tong, Q., Tsubota, K., Vaquero, A., Verdin, E., Guarente, Leonard Pershing

المساهمون: Massachusetts Institute of Technology. Department of Biology, Guarente, Leonard Pershing

المصدر: PMC

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1126/science.329.5995.1012Test; Science; http://hdl.handle.net/1721.1/116434Test; Baur, J. A. et al. “Dietary Restriction: Standing Up for Sirtuins.” Science 329, 5995 (August 2010): 1012–1013 © 2010 American Association for the Advancement of Science; orcid:0000-0003-4064-2510

الإتاحة: https://doi.org/10.1126/science.329.5995.1012Test
http://hdl.handle.net/1721.1/116434Test

المؤلفون: Hayashi, Hideki, Cherpokova, Deya, Martinod, Kimberly, Witsch, Thilo, Wong, Siu Ling, Gallant, Maureen, Cifuni, Stephen M., Wagner, Denisa D., Guarente, Leonard Pershing

المساهمون: Massachusetts Institute of Technology. Department of Biology, Guarente, Leonard Pershing

المصدر: PLoS

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1371/JOURNAL.PONE.0188341Test; PLOS ONE; http://hdl.handle.net/1721.1/116426Test; Hayashi, Hideki et al. “Sirt3 Deficiency Does Not Affect Venous Thrombosis or NETosis Despite Mild Elevation of Intracellular ROS in Platelets and Neutrophils in Mice.” Edited by Nades Palaniyar. PLOS ONE 12, 12 (December 2017): e0188341 © 2017 Hayashi et al; orcid:0000-0003-4064-2510

الإتاحة: https://doi.org/10.1371/JOURNAL.PONE.0188341Test
http://hdl.handle.net/1721.1/116426Test

المؤلفون: Dellinger, Ryan W., Santos, Santiago Roel, Morris, Mark, Evans, Mal, Alminana, Dan, Marcotulli, Eric, Guarente, Leonard Pershing

المساهمون: Massachusetts Institute of Technology. Department of Biology, Guarente, Leonard Pershing

المصدر: Nature

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1038/S41514-017-0016-9Test; npj Aging and Mechanisms of Disease; http://hdl.handle.net/1721.1/116430Test; Dellinger, Ryan W. et al. “Repeat Dose NRPT (nicotinamide Riboside and Pterostilbene) Increases NAD+ Levels in Humans Safely and Sustainably: a Randomized, Double-Blind, Placebo-Controlled Study.” Npj Aging and Mechanisms of Disease 3, 1 (November 2017): 17 © 2017 The Author(s); orcid:0000-0003-4064-2510

الإتاحة: https://doi.org/10.1038/S41514-017-0016-9Test
http://hdl.handle.net/1721.1/116430Test

المؤلفون: Zainabadi, Kayvan, Liu, Cassie J, Guarente, Leonard Pershing

المساهمون: Massachusetts Institute of Technology. Department of Biology, Koch Institute for Integrative Cancer Research at MIT, Zainabadi, Kayvan, Liu, Cassie J, Guarente, Leonard Pershing

المصدر: PLoS

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1371/JOURNAL.PONE.0178520Test; PLOS ONE; http://hdl.handle.net/1721.1/113262Test; Zainabadi, Kayvan et al. “SIRT1 Is a Positive Regulator of the Master Osteoblast Transcription Factor, RUNX2.” Edited by Jung-Eun Kim. PLOS ONE 12, 5 (May 2017): e0178520 © 2017 Zainabadi et al; orcid:0000-0003-4064-2510

الإتاحة: https://doi.org/10.1371/JOURNAL.PONE.0178520Test
http://hdl.handle.net/1721.1/113262Test

المؤلفون: Zainabadi, Kayvan, Liu, Cassie J, Caldwell, Alison L. M., Guarente, Leonard Pershing

المساهمون: Massachusetts Institute of Technology. Department of Biology, Koch Institute for Integrative Cancer Research at MIT, Zainabadi, Kayvan, Liu, Cassie J, Caldwell, Alison L. M., Guarente, Leonard Pershing

المصدر: PLoS

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1371/JOURNAL.PONE.0185236Test; PLOS ONE; http://hdl.handle.net/1721.1/114930Test; Zainabadi, Kayvan et al. “SIRT1 Is a Positive Regulator of in Vivo Bone Mass and a Therapeutic Target for Osteoporosis.” Edited by Jung-Eun Kim. PLOS ONE 12, 9 (September 2017): e0185236 © 2017 Zainabadi et al; orcid:0000-0003-4064-2510

الإتاحة: https://doi.org/10.1371/JOURNAL.PONE.0185236Test
http://hdl.handle.net/1721.1/114930Test

المؤلفون: Imai, Shin-ichiro, Guarente, Leonard Pershing

المساهمون: Massachusetts Institute of Technology. Department of Biology, Paul F. Glenn Center for Biology of Aging Research (Massachusetts Institute of Technology), Koch Institute for Integrative Cancer Research at MIT, Guarente, Leonard Pershing

المصدر: Nature

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1038/NPJAMD.2016.17Test; npj Aging and Mechanisms of Disease; http://hdl.handle.net/1721.1/116435Test; Imai, Shin-ichiro and Leonard Guarente. “It Takes Two to Tango: NAD+ and Sirtuins in Aging/longevity Control.” Npj Aging and Mechanisms of Disease 2, 1 (August 2016): 16017 © 2016 The Author(s); orcid:0000-0003-4064-2510

الإتاحة: https://doi.org/10.1038/NPJAMD.2016.17Test
http://hdl.handle.net/1721.1/116435Test

المؤلفون: Wellman, Alicia S., Metukuri, Mallikarjuna R., Kazgan, Nevzat, Xu, Xiaojiang, Xu, Qing, Ren, Natalie S.X., Shanahan, Michael T., Kang, Ashley, Chen, Willa, Azcarate-Peril, M. Andrea, Gulati, Ajay S., Fargo, David C., Li, Xiaoling, Guarente, Leonard Pershing, Czopik, Agnieszka

المساهمون: Massachusetts Institute of Technology. Department of Biology, Czopik, Agnieszka K, Guarente, Leonard Pershing

المصدر: PMC

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1053/J.GASTRO.2017.05.022Test; Gastroenterology; http://hdl.handle.net/1721.1/118956Test; Wellman, Alicia S., et al. “Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota.” Gastroenterology, vol. 153, no. 3, Sept. 2017, pp. 772–86.; orcid:0000-0003-4064-2510

الإتاحة: https://doi.org/10.1053/J.GASTRO.2017.05.022Test
http://hdl.handle.net/1721.1/118956Test

المؤلفون: Das, Abhirup, Huang, George X., Bonkowski, Michael S., Longchamp, Alban, Li, Catherine, Schultz, Michael B., Kim, Lynn-Jee, Osborne, Brenna, Joshi, Sanket, Lu, Yuancheng, Treviño-Villarreal, Jose Humberto, Kang, Myung-Jin, Hung, Tzong-tyng, Lee, Brendan, Williams, Eric O, Igarashi, Masaki, Mitchell, James R., Wu, Lindsay E., Turner, Nigel, Arany, Zolt, Guarente, Leonard Pershing, Sinclair, David A.

المساهمون: Massachusetts Institute of Technology. Department of Biology, Paul F. Glenn Center for Biology of Aging Research (Massachusetts Institute of Technology)

المصدر: PMC

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1016/j.cell.2018.02.008Test; Cell; https://hdl.handle.net/1721.1/126072Test; Das, Abhirup et al. "Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging." Cell 173, 1 (March 2018): 74-89 © 2018 Elsevier

الإتاحة: https://doi.org/10.1016/j.cell.2018.02.008Test
https://hdl.handle.net/1721.1/126072Test

المؤلفون: Igarashi, Masaki, Miura, Masaomi, Williams, Eric O, Jaksch, Frank, Kadowaki, Takashi, Yamauchi, Toshimasa, Guarente, Leonard Pershing

المساهمون: Massachusetts Institute of Technology. Department of Biology, Paul F. Glenn Center for Biology of Aging Research (Massachusetts Institute of Technology), Koch Institute for Integrative Cancer Research at MIT

المصدر: Wiley

وصف الملف: application/pdf

العلاقة: https://dx.doi.org/10.1111/acel.12935Test; Aging Cell; https://hdl.handle.net/1721.1/125404Test; Igarashi, Masaki et al. "NAD + supplementation rejuvenates aged gut adult stem cells." Aging Cell 18,3 (June 2019): e12935 © 2019 The Author(s).

الإتاحة: https://doi.org/10.1111/acel.12935Test
https://hdl.handle.net/1721.1/125404Test

المؤلفون: Chen, Hanqing, Shen, Feng, Sherban, Alex, Nocon, Allison, Li, Yu, Wang, Hua, Xu, Ming-Jiang, Rui, Xianliang, Han, Jinyan, Jiang, Bingbing, Lee, Donghwan, Li, Na, Keyhani-Nejad, Farnaz, Fan, Jian-gao, Liu, Feng, Kamat, Amrita, Musi, Nicolas, Guarente, Leonard Pershing, Pacher, Pal, Gao, Bin, Zang, Mengwei

المساهمون: Massachusetts Institute of Technology. Department of Biology

المصدر: PMC

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1002/hep.29849Test; Hepatology; https://hdl.handle.net/1721.1/126133Test; Chen, Hanqing et al. "DEP domain-containing mTOR-interacting protein suppresses lipogenesis and ameliorates hepatic steatosis and acute-on-chronic liver injury in alcoholic liver disease." Hepatology 68, 2 (May 2018): 496-514 © 2018 American Association for the Study of Liver Diseases

الإتاحة: https://doi.org/10.1002/hep.29849Test
https://hdl.handle.net/1721.1/126133Test