Nrf2-interacting nutrients and COVID-19: time for research to develop adaptation strategies

التفاصيل البيبلوغرافية
العنوان:	Nrf2-interacting nutrients and COVID-19: time for research to develop adaptation strategies
المؤلفون:	Bousquet, J, Cristol, J-P, Czarlewski, W, Anto, JM, Martineau, A, Haahtela, T, Fonseca, SC, Iaccarino, G, Blain, H, Fiocchi, A, Canonica, GW, Fonseca, JA, Vidal, A, Choi, H-J, Kim, HJ, Le Moing, V, Reynes, J, Sheikh, A, Akdis, CA, Zuberbier, T, Abdul Latiff, AH, Abdullah, B, Aberer, W, Abusada, N, Adcock, I, Afani, A, Agache, I, Aggelidis, X, Agustin, J, Akdis, M, Al-Ahmad, M, Al-Zahab Bassam, A, Alburdan, H, Aldrey-Palacios, O, Alvarez Cuesta, E, Alwan Salman, H, Alzaabi, A, Amade, S, Ambrocio, G, Angles, R, Annesi-Maesano, I, Ansotegui, IJ, Ara Bardajo, P, Arasi, S, Arrais, M, Arshad, H, Artesani, M-C, Asayag, E, Avolio, F, Azhari, K, Bachert, C, Bagnasco, D, Baiardini, I, Bajrovic, N, Bakakos, P, Bakeyala Mongono, S, Balotro-Torres, C, Barba, S, Barbara, C, Barbosa, E, Barreto, B, Bartra, J, Basagana, X, Bateman, ED, Battur, L, Bedbrook, A, Bedolla Barajas, M, Beghe, B, Bekere, A, Bel, E, Ben Kheder, A, Benson, M, Berghea, E-C, Bergmann, K-C, Bernardini, R, Bernstein, D, Bewick, M, Bialek, S, Bialoszewski, A, Bieber, T, Billo, NE, Bilo, M-B, Bindslev-Jensen, C, Bjermer, L, Bobolea, I, Bochenska Marciniak, M, Bond, C, Boner, A, Bonini, M, Bonini, S, Bosnic-Anticevich, S, Bosse, I, Botskariova, S, Bouchard, J, Boulet, L-P, Bourret, R, Bousquet, P, Braido, F, Briggs, A, Brightling, CE, Brozek, J, Brussino, L, Buhl, R, Bumbacea, R, Buquicchio, R, Burguete Cabanas, M-T, Bush, A, Busse, WW, Buters, J, Caballero-Fonseca, F, Calderon, MA, Calvo, M, Camargos, P, Camuzat, T, Canevari, FR, Cano, A, Capriles-Hulett, A, Caraballo, L, Cardona, V, Carlsen, K-H, Carmona Pirez, J, Caro, J, Carr, W, Carreiro-Martins, P, Carreon-Asuncion, F, Carriazo, A-M, Carrion y Ribas, C, Casale, T, Castor, M-A, Castro, E, Caviglia, AG, Cecchi, L, Cepeda Sarabia, A, Chalubinski, M, Chandrasekharan, R, Chang, Y-S, Chato-Andeza, V, Chatzi, L, Chatzidaki, C, Chavannes, NH, Chaves Loureiro, C, Chavez Garcia, A-A, Chelninska, M, Chen, Y, Cheng, L, Chinthrajah, S, Chivato, T, Chkhartishvili, E, Christoff, G, Chrystyn, H, Chu, DK, Chua, A, Chuchalin, A, Chung, KF, Ciceran, A, Cingi, C, Ciprandi, G, Cirule, I, Coelho, A-C, Compalati, E, Constantinidis, J, Correia de Sousa, J, Costa, EM, Costa, D, del Carmen Costa Dominguez, M, Coste, A, Cottini, M, Cox, L, Crisci, C, Crivellaro, MA, Cruz, AA, Cullen, J, Custovic, A, Cvetkovski, B, D'Amato, G, da Silva, J, Dahl, R, Dahlen, S-E, Daniilidis, V, Darjazini Nahhas, L, Darsow, U, Davies, J, de Blay, F, De Feo, G, De Guia, E, de la Torre Navarrete, J-R, de los Santos, C, De Manuel Keenoy, E, De Vries, G, Deleanu, D, Demoly, P, Denburg, J, Devillier, P, Didier, A, Dimic Janjic, S, Dimou, M, Dinh-Xuan, AT, Djukanovic, R, Do Ceu Texeira, M, Dokic, D, Dominguez Silva, MG, Douagui, H, Douladiris, N, Doulaptsi, M, Dray, G, Dubakiene, R, Dupas, E, Durham, S, Duse, M, Dykewicz, M, Ebo, D, Edelbaher, N, Eiwegger, T, Eklund, P, El-Gamal, Y, El-Sayed, ZA, El-Sayed, SS, El-Seify, M, Emuzyte, R, Enecilla, L, Erhola, M, Espinoza, H, Espinoza Contreras, JG, Farrell, J, Fernandez, L, Fimbres Jimenez, P, Fink Wagner, A, Fokkens, WJ, Folletti, L, Fontaine, J-F, Forastiere, F, Fuentes Perez, JM, Gaerlan-Resureccion, E, Gaga, M, Galvez Romero, JL, Gamkrelidze, A, Garcia, A, Garcia Cobas, CY, de la Luz Hortensia Garcia Cruz, M, Ortiz, VG, Gayraud, J, Gelardi, M, Gemicioglu, B, Gennimata, D, Genova, S, Gereda, J, Gerth van Wijk, R, Giuliano, A, Gomez, R-M, Gonzalez Ballester, M-A, Gonzalez Diaz, S, Gotua, M, Grigoreas, C, Grisle, I, Guidacci, M, Guldemond, N, Gutter, Z, Guzman, A, Halloum, R, Halpin, D, Hamelmann, E, Hammadi, S, Harvey, R, Heffler, E, Heinrich, J, Hejjaoui, A, Hellquist-Dahl, B, Hernandez Velazquez, L, Hew, M, Hossny, E, Howarth, P, Hrubisko, M, Huerta Villalobos, YR, Humbert, M, Husain, S, Hyland, M, Ibrahim, M, Ilina, N, Illario, M, Incorvaia, C, Infantino, A, Irani, C, Ispayeva, Z, Ivancevich, JC, Jares, EEJ, Jarvis, D, Jassem, E, Jenko, K, Jimeneracruz Uscanga, RD, Johnston, SL, Joos, G, Jost, M, Julge, K, Jung, K-S, Just, J, Jutel, M, Kaidashev, I, Kalayci, O, Kalyoncu, F, Kapsali, J, Kardas, P, Karjalainen, J, Kasala, CA, Katotomichelakis, M, Kavaliukaite, L, Bennoor, KS, Keil, T, Keith, P, Khaitov, M, Khaltaev, N, Kim, Y-Y, Kirenga, B, Kleine-Tebbe, J, Klimek, L, Ko, FW, Koffi N'Goran, B, Kompoti, E, Kopac, P, Koppelman, G, Koren Jeverica, A, Koskinen, S, Kosnik, M, Kostka, T, Kostov, KV, Kowalski, ML, Kralimarkova, T, Kramer Vrscaj, K, Kraxner, H, Kreft, S, Kritikos, V, Kudlay, D, Kuitunen, M, Kull, I, Kuna, P, Kupczyk, M, Kvedariene, V, Kyriakakou, M, Lalek, N, Landi, M, Lane, S, Larenas-Linnemann, DE, Lau, S, Laune, D, Lavrut, J, Le, L, Lenzenhuber, M, Leo, G, Lessa, M, Levin, M, Li, J, Lieberman, P, Liotta, G, Lipworth, B, Liu, X, Lobo, R, Lodrup Carlsen, KC, Lombardi, C, Louis, R, Loukidis, S, Lourenco, O, Luna Pech, JA, Madjar, B, Maggi, E, Magnan, A, Mahboub, B, Mair, A, Maitland van der Zee, A-H, Makela, M, Makris, M, Malling, H-J, Mandajieva, M, Manning, P, Manousakis, M, Maragoudakis, P, Marseglia, G, Marshall, G, Masjedi, MR, Maspero, JF, Matta Campos, JJ, Maurer, M, Mavale-Manuel, S, Meco, C, Melen, E, Melioli, G, Melo-Gomes, E, Meltzer, EO, Menditto, E, Menzies-Gow, A, Merk, H, Michel, J-P, Micheli, Y, Miculinic, N, Midao, L, Mihaltan, F, Mikos, N, Milanese, M, Milenkovic, B, Mitsias, D, Moalla, B, Moda, G, Mogica Martinez, MD, Mohammad, Y, Moharra, F-M, Moin, M, Molimard, M, Momas, I, Mommers, M, Monaco, A, Montefort, S, Montenegro, L-E, Monti, R, Mora, D, Morais-Almeida, M, Mosges, R, Mostafa, BE, Mullol, J, Munter, L, Muraro, A, Murray, R, Musarra, A, Mustakov, T, Naclerio, R, Nadeau, KC, Nadif, R, Nakonechna, A, Namazova-Baranova, L, Navarro-Locsin, G, Neffen, H, Nekam, K, Neou, A, Nettis, E, Neuberger, D, Nicod, L, Nicola, S, Niederberger-Leppin, V, Niedoszytko, M, Nieto, A, Novellino, E, Nunes, E, Nyembue, D, O'Hehir, RE, Odjakova, C, Ohta, K, Okamoto, Y, Okubo, K, Oliver, B, Onorato, GL, Orru, MP, Ouedraogo, S, Ouoba, K, Padilla, F-J, Paggiaro, PL, Pagkalos, A, Pajno, G, Pala, G, Palaniappan, SP, Pali-Scholl, I, Palkonen, S, Palmer, S, Panaitescu Bunu, C, Panzner, P, Papadopoulos, NG, Papanikolaou, V, Papi, A, Paralchev, B, Paraskevopoulos, G, Park, H-S, Passalacqua, G, Patella, V, Pavord, I, Pawankar, R, Pedersen, S, Peleve, S, Pellegino, S, Pereira, A, Pereira, M, Perez, T, Perna, A, Peroni, D, Pfaar, O, Pham-Thi, N, Pigearias, B, Pin, I, Piskou, K, Pitsios, C, Plavec, D, Poethig, D, Pohl, W, Poplas Susic, A, Popov, TA, Portejoie, F, Potter, P, Poulsen, L, Prados-Torres, A, Prarros, F, Price, D, Prokopakis, E, Puggioni, F, Puig-Domenech, E, Puy, R, Rabe, K, Rabotti, S, Raciborski, F, Ramos, J, Recalcati, C, Recto, MT, Reda, SM, Regateiro, FS, Reider, N, Reitsma, S, Repka-Ramirez, S, Ridolo, E, Rimmer, J, Rivero Yeverino, D, Rizzo, JA, Robalo-Cordeiro, C, Roberts, G, Robles, K, Roche, N, Rodriguez Gonzalez, M, Rodriguez Zagal, E, Rolla, G, Rolland, C, Roller-Wirnsberger, R, Roman Rodriguez, M, Romano, A, Romantowski, J, Rombaux, P, Romualdez, J, Rosado-Pinto, J, Rosario, N, Rosenwasser, L, Rossi, O, Rottem, M, Rouadi, PW, Rovina, N, Rozman Sinur, I, Ruiz, M, Ruiz Segura, LT, Ryan, D, Sagara, H, Sakai, D, Sakurai, D, Saleh, W, Salimaki, J, Samitas, K, Samolinski, B, Sanchez Coronel, MG, Sanchez-Borges, M, Sanchez-Lopez, J, Sansonna, M, Sarafoleanu, C, Sarquis Serpa, F, Sastre, J, Savi, E, Savonyte, A, Sawaf, B, Scadding, GK, Scheire, S, Schmid-Grendelmeier, P, Schuhl, JF, Schunemann, H, Schvalbova, M, Schwarze, J, Scichilone, N, Senna, G, Sepulveda, C, Serrano, E, Shamai, S, Shields, M, Shishkov, V, Siafakas, N, Simeonov, A, Simons, EFER, Sisul, JC, Sitkauskiene, B, Skrindo, I, Soklic Kosak, T, Sole, D, Sondermann, M, Sooronbaev, T, Soto-Martinez, M, Soto-Quiros, M, Pinto, BS, Sova, M, Soyka, M, Specjalski, K, Sperl, A, Spranger, O, Stamataki, S, Stefanaki, L, Stellato, C, Stelmach, R, Strandberg, T, Stute, P, Subramaniam, A, Suppli Ulrik, C, Sutherland, M, Sylvestre, S, Syrigou, A, Taborda Barata, L, Takovska, N, Tan, R, Tan, F, Tan, V, Tang, IP, Taniguchi, M, Tannert, L, Tantilipikorn, P, Tattersall, J, Tesi, F, Thieme, U, Thijs, C, Thomas, M, To, T, Todo-Bom, AM, Togias, A, Tomazic, P-V, Tomic-Spiric, V, Toppila-Salmi, S, Torres Jaen, M-J, Toskala, E, Triggiani, M, Triller, N, Triller, K, Tsiligianni, I, Uberti, M, Ulmeanu, R, Urbancic, J, Urrutia Pereira, M, Vachova, M, Valdes, F, Valenta, R, Valentin Rostan, M, Valero, A, Valiulis, A, Vallianatou, M, Valovirta, E, Van Eerd, M, Van Ganse, E, van Hage, M, Vandenplas, O, Vasankari, T, Vassileva, D, Velasco Munoz, C, Ventura, MT, Vera-Munoz, C, Viart, F, Vicheva, D, Vichyanond, P, Vidgren, P, Viegi, G, Vogelmeier, C, Von Hertzen, L, Vontetsianos, T, Vourdas, D, Tran Thien Quan, V, Wagenmann, M, Walker, S, Wallace, D, De Wang, Y, Waserman, S, Wehner, K, Wickman, M, Williams, S, Williams, D, Wilson, N, Wong, G, Woo, K, Wozniak, L, Wright, J, Wroczynski, P, Xepapadaki, P, Yakovliev, P, Yamaguchi, M, Yan, K, Yap, YY, Yassin, M, Yawn, B, Yiallouros, P, Yorgancioglu, A, Yoshihara, S, Young, I, Yusuf, OB, Zaidi, A, Zaitoun, F, Zalud, P, Zar, H, Zedda, MT, Zernotti, ME, Zhang, L, Zhong, N, Zidarn, M, Zubrinich, C, Grp, ARIA, group, TARIA
بيانات النشر:	Springer Nature
سنة النشر:	2020
المجموعة:	Queen Mary University of London: Queen Mary Research Online (QMRO)
مصطلحات موضوعية:	COVID-19, Nrf2, Foods, Nutrients, Insulin resistance, Obesity, TRPA1
الوصف:	There are large between- and within-country variations in COVID-19 death rates. Some very low death rate settings such as Eastern Asia, Central Europe, the Balkans and Africa have a common feature of eating large quantities of fermented foods whose intake is associated with the activation of the Nrf2 (Nuclear factor (erythroid-derived 2)-like 2) anti-oxidant transcription factor. There are many Nrf2-interacting nutrients (berberine, curcumin, epigallocatechin gallate, genistein, quercetin, resveratrol, sulforaphane) that all act similarly to reduce insulin resistance, endothelial damage, lung injury and cytokine storm. They also act on the same mechanisms (mTOR: Mammalian target of rapamycin, PPARγ:Peroxisome proliferator-activated receptor, NFκB: Nuclear factor kappa B, ERK: Extracellular signal-regulated kinases and eIF2α:Elongation initiation factor 2α). They may as a result be important in mitigating the severity of COVID-19, acting through the endoplasmic reticulum stress or ACE-Angiotensin-II-AT1R axis ( AT1R) pathway. Many Nrf2-interacting nutrients are also interacting with TRPA1 and/or TRPV1. Interestingly, geographical areas with very low COVID-19 mortality are those with the lowest prevalence of obesity (Sub-Saharan Africa and Asia). It is tempting to propose that Nrf2-interacting foods and nutrients can re-balance insulin resistance and have a significant effect on COVID-19 severity. It is therefore possible that the intake of these foods may restore an optimal natural balance for the Nrf2 pathway and may be of interest in the mitigation of COVID-19 severity.
نوع الوثيقة:	article in journal/newspaper
اللغة:	unknown
العلاقة:	CLINICAL AND TRANSLATIONAL ALLERGY; Bousquet, J., Cristol, JP., Czarlewski, W. et al. Nrf2-interacting nutrients and COVID-19: time for research to develop adaptation strategies. Clin Transl Allergy 10, 58 (2020). https://doi.org/10.1186/s13601-020-00362-7Test; ARTN 58; https://qmro.qmul.ac.uk/xmlui/handle/123456789/69882Test
DOI:	10.1186/s13601-020-00362-7
الإتاحة:	https://doi.org/10.1186/s13601-020-00362-7Test https://qmro.qmul.ac.uk/xmlui/handle/123456789/69882Test
حقوق:	This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creatTest iveco mmons .org/licen ses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creatTest iveco mmons .org/publi cdoma in/ zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. ; © The Author(s) 2020.
رقم الانضمام:	edsbas.6F578919
قاعدة البيانات:	BASE

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الوصف
DOI:	10.1186/s13601-020-00362-7