دورية أكاديمية
Reactivation of Chagas Disease in a Patient With Follicular Lymphoma Diagnosed by Means of Quantitative Real-Time Polymerase Chain Reaction
| العنوان: | Reactivation of Chagas Disease in a Patient With Follicular Lymphoma Diagnosed by Means of Quantitative Real-Time Polymerase Chain Reaction |
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| المؤلفون: | Garzón, Maria I., Sánchez, Ariel G., Goy, Maria C., Alvarellos, Teresita, Zarate, Abel H., Basquiera, Ana L., Garcia, Juan J., Caeiro, Juan P. |
| المصدر: | Open Forum Infectious Diseases ; volume 2, issue 2 ; ISSN 2328-8957 |
| بيانات النشر: | Oxford University Press (OUP) |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Infectious Diseases, Oncology |
| الوصف: | We report a case of Chagas disease reactivation in a patient with stage IIb follicular lymphoma in the cecum. He was admitted to the hospital with neutropenia and fever. He had a history of right hemicolectomy 6 months earlier and had received the sixth cycle of chemotherapy with cyclophosphamide/doxorubicin/vincristine/prednisone/rituximab. Blood and urine cultures were negative, but the fever persisted. Reactivation of Chagas disease was confirmed by means of quantitative real-time polymerase chain reaction (qRT-PCR). Parasitic load was 577 950 parasite equivalents/mL. The patient began treatment with benznidazole 5 mg/k per day every 12 hours. After 1 month, the qRT-PCR control was undetectable. The patient completed 60 days of treatment and is currently asymptomatic. Trypanosoma cruzi qRT-PCR may become a useful diagnostic method for reactivation of Chagas disease. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1093/ofid/ofv060 |
| الإتاحة: | https://doi.org/10.1093/ofid/ofv060Test http://academic.oup.com/ofid/article-pdf/2/2/ofv060/33621082/ofv060.pdfTest |
| حقوق: | http://creativecommons.org/licenses/by-nc-nd/4.0Test/ |
| رقم الانضمام: | edsbas.53566CE5 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/ofid/ofv060 |
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