المؤلفون: Harnden, Alice C., Davis, Owen A., Box, Gary M., Hayes, Angela, Johnson, Louise D., Henley, Alan T., de Haven Brandon, Alexis K., Valenti, Melanie, Cheung, Kwai-Ming J., Brennan, Alfie, Huckvale, Rosemary, Pierrat, Olivier A., Talbot, Rachel, Bright, Michael D., Akpinar, Hafize Aysin, Miller, Daniel S. J., Tarantino, Dalia, Gowan, Sharon, de Klerk, Selby, McAndrew, Peter Craig, Le Bihan, Yann-Vaï, Meniconi, Mirco, Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Bellenie, Benjamin R., Hoelder, Swen

المساهمون: NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research, Cancer Research UK, CRT Pioneer Fund, Sixth Element Capital

المصدر: Journal of Medicinal Chemistry ; volume 66, issue 8, page 5892-5906 ; ISSN 0022-2623 1520-4804

الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c00155Test

المؤلفون: Pasqua, A. Elisa, Sharp, Swee Y., Chessum, Nicola E. A., Hayes, Angela, Pellegrino, Loredana, Tucker, Michael J., Miah, Asadh, Wilding, Birgit, Evans, Lindsay E., Rye, Carl S., Mok, N. Yi, Liu, Manjuan, Henley, Alan T., Gowan, Sharon, De Billy, Emmanuel, te Poele, Robert, Powers, Marissa, Eccles, Suzanne A., Clarke, Paul A., Raynaud, Florence I., Workman, Paul, Jones, Keith, Cheeseman, Matthew D.

المساهمون: Cancer Research UK, Battle Against Cancer Investment Trust, Cancer Research Technology Pioneer Fund

المصدر: Journal of Medicinal Chemistry ; volume 66, issue 8, page 5907-5936 ; ISSN 0022-2623 1520-4804

الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c00156Test

المؤلفون: Huckvale, Rosemary, Harnden, Alice C., Cheung, Kwai-Ming J., Pierrat, Olivier A., Talbot, Rachel, Box, Gary M., Henley, Alan T., de Haven Brandon, Alexis K., Hallsworth, Albert E., Bright, Michael D., Akpinar, Hafize Aysin, Miller, Daniel S. J., Tarantino, Dalia, Gowan, Sharon, Hayes, Angela, Gunnell, Emma A., Brennan, Alfie, Davis, Owen A., Johnson, Louise D., de Klerk, Selby, McAndrew, Craig, Le Bihan, Yann-Vaï, Meniconi, Mirco, Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Bellenie, Benjamin R., Hoelder, Swen

المساهمون: Cancer Research UK, Sixth Element Capital

المصدر: Journal of Medicinal Chemistry ; volume 65, issue 12, page 8191-8207 ; ISSN 0022-2623 1520-4804

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

الإتاحة: https://doi.org/10.1021/acs.jmedchem.1c02175Test

المؤلفون: Bellenie, Benjamin R., Cheung, Kwai-Ming J., Varela, Ana, Pierrat, Olivier A., Collie, Gavin W., Box, Gary M., Bright, Michael D., Gowan, Sharon, Hayes, Angela, Rodrigues, Matthew J., Shetty, Kartika N., Carter, Michael, Davis, Owen A., Henley, Alan T., Innocenti, Paolo, Johnson, Louise D., Liu, Manjuan, de Klerk, Selby, Le Bihan, Yann-Vaï, Lloyd, Matthew G., McAndrew, P. Craig, Shehu, Erald, Talbot, Rachel, Woodward, Hannah L., Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Hoelder, Swen

المساهمون: Cancer Research UK, European investment fund, Cancer Research Technology

المصدر: Journal of Medicinal Chemistry ; volume 63, issue 8, page 4047-4068 ; ISSN 0022-2623 1520-4804

الإتاحة: https://doi.org/10.1021/acs.jmedchem.9b02076Test

المؤلفون: Read, Martin, Harrison, R. John, Romagnoli, Barbara, Tanious, Farial A., Gowan, Sharon H., Reszka, Anthony P., Wilson, W. David, Kelland, Lloyd R., Neidle, Stephen

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2001 Apr . 98(9), 4844-4849.

الوصول الحر: https://www.jstor.org/stable/3055526Test

المؤلفون: Andrejeva, Gabriela, Gowan, Sharon, Lin, Gigin, Wong Te Fong, Anne Christine LF, Shamsaei, Elham, Parkes, Harry G., Mui, James, Raynaud, Florence I., Asad, Yasmin, Vizcay-Barrena, Gema, Nikitorowicz-Buniak, Joanna, Valenti, Melanie, Howell, Louise, Fleck, Roland A., Martin, Lesley Ann, Kirkin, Vladimir, Leach, Martin O., Chung, Yuen Li

المصدر: Andrejeva , G , Gowan , S , Lin , G , Wong Te Fong , A C LF , Shamsaei , E , Parkes , H G , Mui , J , Raynaud , F I , Asad , Y , Vizcay-Barrena , G , Nikitorowicz-Buniak , J , Valenti , M , Howell , L , Fleck , R A , Martin , L A , Kirkin , V , Leach , M O & Chung , Y L 2019 , ' De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy ' ....

مصطلحات موضوعية: Autophagosome, autophagy, choline phospholipids, CTP:phosphocholine cytidylyltransferase, phosphatidylcholine, propargylcholine

الإتاحة: https://doi.org/10.1080/15548627.2019.1659608Test
https://kclpure.kcl.ac.uk/portal/en/publications/ef637dcb-362c-4fd8-9f92-f838ce4f1d45Test
http://www.scopus.com/inward/record.url?scp=85073817643&partnerID=8YFLogxKTest

المؤلفون: Al-Saffar, Nada M. S., Troy, Helen, Wong Te Fong, Anne-Christine, Paravati, Roberta, Jackson, L. Elizabeth, Gowan, Sharon, Boult, Jessica K. R., Robinson, Simon P., Eccles, Suzanne A., Yap, Timothy A., Leach, Martin O., Chung, Yuen-Li

المصدر: British Journal of Cancer ; volume 119, issue 9, page 1118-1128 ; ISSN 0007-0920 1532-1827

مصطلحات موضوعية: Cancer Research, Oncology

الإتاحة: https://doi.org/10.1038/s41416-018-0242-3Test
http://www.nature.com/articles/s41416-018-0242-3Test
http://www.nature.com/articles/s41416-018-0242-3.pdfTest

المؤلفون: Tucker, Elizabeth R., Tall, Jennifer R., Danielson, Laura S., Gowan, Sharon, Jamin, Yann, Robinson, Simon P., Banerji, Udai, Chesler, Louis

المساهمون: Medical Research Council and SPARKS Clinical Research Training Fellowship, Abbie's Fund, Cancer Research UK Project

المصدر: Molecular Oncology ; volume 11, issue 8, page 996-1006 ; ISSN 1574-7891 1878-0261

الإتاحة: https://doi.org/10.1002/1878-0261.12069Test

المؤلفون: Clarke, Paul A., Ortiz-Ruiz, Maria-Jesus, TePoele, Robert, Adeniji-Popoola, Olajumoke, Box, Gary, Court, Will, Czasch, Stefanie, El Bawab, Samer, Esdar, Christina, Ewan, Ken, Gowan, Sharon, De Haven Brandon, Alexis, Hewitt, Phllip, Hobbs, Stephen M., Kaufmann, Wolfgang, Mallinger, Aurélie, Raynaud, Florence, Roe, Toby, Rohdich, Felix, Schiemann, Kai, Simon, Stephanie, Schneider, Richard, Valenti, Melanie, Weigt, Stefan, Blagg, Julian, Blaukat, Andree, Dale, Trevor C., Eccles, Suzanne A., Hecht, Stefan, Urbahns, Klaus, Workman, Paul, Wienke, Dirk

وصف الملف: application/pdf

العلاقة: https://orca.cardiff.ac.uk/id/eprint/96966/1/elife-20722-v3.pdfTest; Clarke, Paul A., Ortiz-Ruiz, Maria-Jesus, TePoele, Robert, Adeniji-Popoola, Olajumoke, Box, Gary, Court, Will, Czasch, Stefanie, El Bawab, Samer, Esdar, Christina, Ewan, Ken orcid:0000-0001-6622-9009 orcid:0000-0001-6622-9009, Gowan, Sharon, De Haven Brandon, Alexis, Hewitt, Phllip, Hobbs, Stephen M., Kaufmann, Wolfgang, Mallinger, Aurélie, Raynaud, Florence, Roe, Toby, Rohdich, Felix, Schiemann, Kai, Simon, Stephanie, Schneider, Richard, Valenti, Melanie, Weigt, Stefan, Blagg, Julian, Blaukat, Andree, Dale, Trevor C. https://orca.cardiff.ac.uk/view/cardiffauthors/A050728Q.htmlTest orcid:0000-0002-4880-9963 orcid:0000-0002-4880-9963, Eccles, Suzanne A., Hecht, Stefan, Urbahns, Klaus, Workman, Paul and Wienke, Dirk 2016. Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases. eLife 5 , e20722. 10.7554/eLife.20722 https://doi.org/10.7554/eLife.20722Test file https://orca.cardiff.ac.uk/id/eprint/96966/1/elife-20722-v3.pdfTest

الإتاحة: https://doi.org/10.7554/eLife.20722Test
https://orca.cardiff.ac.uk/id/eprint/96966Test/
https://orca.cardiff.ac.uk/id/eprint/96966/1/elife-20722-v3.pdfTest

المؤلفون: Naseem, Afia, Pal, Akos, Gowan, Sharon, Asad, Yasmin, Donovan, Adam, Temesszentandrási-Ambrus, Csilla, Kis, Emese, Gaborik, Zsuzsanna, Bhalay, Gurdip, Raynaud, Florence

المصدر: Cells (2073-4409); Oct2022, Vol. 11 Issue 20, p3286-N.PAG, 20p

مصطلحات موضوعية: LIQUID chromatography-mass spectrometry, METABOLOMICS, CELL permeability, THYMIDYLATE synthase, METHYLENETETRAHYDROFOLATE reductase