المؤلفون: Libardo, M. Daben J, Duncombe, Caroline J., Green, Simon R., Wyatt, Paul G., Thompson, Stephen, Ray, Peter C., Ioerger, Thomas R., Oh, Sangmi, Goodwin, Michael B., Boshoff, Helena I. M., Barry III, Clifton E.

المصدر: Libardo , M D J , Duncombe , C J , Green , S R , Wyatt , P G , Thompson , S , Ray , P C , Ioerger , T R , Oh , S , Goodwin , M B , Boshoff , H I M & Barry III , C E 2021 , ' Resistance of Mycobacterium tuberculosis to indole 4-carboxamides occurs through alterations in drug metabolism and tryptophan biosynthesis ' , Cell Chemical Biology , vol. 28 , no. 8 , pp. 1180-1191.e20 . https://doi.org/10.1016/j.chembiol.2021.02.023Test

مصطلحات موضوعية: tuberculosis, drug mechanism of action, pro-drug, tryptophan metabolism, antimetabolite, /dk/atira/pure/subjectarea/asjc/3000/3002, name=Drug Discovery, /dk/atira/pure/subjectarea/asjc/1300/1313, name=Molecular Medicine, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1308, name=Clinical Biochemistry, /dk/atira/pure/subjectarea/asjc/3000/3004, name=Pharmacology

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/0a2339ec-4429-49c5-a052-1a47caae007dTest

الإتاحة: https://doi.org/10.1016/j.chembiol.2021.02.023Test
https://discovery.dundee.ac.uk/en/publications/0a2339ec-4429-49c5-a052-1a47caae007dTest
https://discovery.dundee.ac.uk/ws/files/57600215/1_s2.0_S2451945621001082_main.pdfTest
http://www.scopus.com/inward/record.url?scp=85112587717&partnerID=8YFLogxKTest

المؤلفون: Park, Yumi, Ahn, Yong-Mo, Jonnala, Surendranadha, Oh, Sangmi, Fisher, Julia M., Goodwin, Michael B., Loerger, Thomas R., Via, Laura E., Bayliss, Tracy, Green, Simon R., Ray, Peter C., Wyatt, Paul G., Barry, Clifton E., Boshoff, Helena I.

المصدر: Park , Y , Ahn , Y-M , Jonnala , S , Oh , S , Fisher , J M , Goodwin , M B , Loerger , T R , Via , L E , Bayliss , T , Green , S R , Ray , P C , Wyatt , P G , Barry , C E & Boshoff , H I 2019 , ' Inhibition of CorA dependent Magnesium Homeostasis is cidal in Mycobacterium tuberculosis ' , Antimicrobial Agents and Chemotherapy , vol. 63 , no. 10 , e01006-19 . https://doi.org/10.1128/AAC.01006-19Test

مصطلحات موضوعية: CorA transporter, Magnesium homeostasis, Mycobacterium tuberculosis, Pyrimidinetrione amide, Structure-activity relationship, /dk/atira/pure/subjectarea/asjc/3000/3004, name=Pharmacology, /dk/atira/pure/subjectarea/asjc/2700/2736, name=Pharmacology (medical), /dk/atira/pure/subjectarea/asjc/2700/2725, name=Infectious Diseases

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/a34c43d0-5345-4d49-af33-abc1d7b43758Test

الإتاحة: https://doi.org/10.1128/AAC.01006-19Test
https://discovery.dundee.ac.uk/en/publications/a34c43d0-5345-4d49-af33-abc1d7b43758Test
https://discovery.dundee.ac.uk/ws/files/37263412/Author_Accepted_Manuscript.pdfTest
http://www.scopus.com/inward/record.url?scp=85072570201&partnerID=8YFLogxKTest

المؤلفون: Lin, Philana Ling, Dartois, Veronique, Johnston, Paul J., Janssen, Christopher, Via, Laura, Goodwin, Michael B., Klein, Edwin, Barry, Clifton E., Flynn, JoAnne L.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2012 Aug . 109(35), 14188-14193.

الوصول الحر: https://www.jstor.org/stable/41701664Test

المؤلفون: Libardo, M. Daben J., Duncombe, Caroline J., Green, Simon R., Wyatt, Paul, Thompson, Stephen, Ray, Peter C., Ioerger, Thomas R., Oh, Sangmi, Goodwin, Michael B., Boshoff, Helena I.M., Barry, Clifton E.

المصدر: SSRN Electronic Journal ; ISSN 1556-5068

الإتاحة: https://doi.org/10.2139/ssrn.3724670Test

المؤلفون: Watanabe, Shinya, Zimmermann, Michael, Goodwin, Michael B., Sauer, Uwe, id_orcid:0 000-0002-5923-0770, Barry, Clifton E., Boshoff, Helena I.

المصدر: PLoS Pathogens, 7 (10)

وصف الملف: application/application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/wos/000296734300017; http://hdl.handle.net/20.500.11850/40728Test

الإتاحة: https://doi.org/20.500.11850/40728Test
https://doi.org/10.3929/ethzTest-b-000040728
https://doi.org/10.1371/journal.ppat.1002287Test
https://hdl.handle.net/20.500.11850/40728Test

المؤلفون: McDougall, Jean A., Blair, Cindy K., Wiggins, Charles L., Goodwin, Michael B., Chiu, Vi K., Rajput, Ashwani, Kinney, Anita Y.

المساهمون: National Cancer Institute

المصدر: Journal of Cancer Survivorship ; volume 13, issue 3, page 459-467 ; ISSN 1932-2259 1932-2267

مصطلحات موضوعية: Oncology (nursing), Oncology

الإتاحة: https://doi.org/10.1007/s11764-019-00767-9Test

المؤلفون: Li, Xiaojin, Manjunatha, Ujjini H., Goodwin, Michael B., Knox, John E., Lipinski, Christopher A., Keller, Thomas H., Barry, Clifton E., Dowd, Cynthia S.

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 18, issue 7, page 2256-2262 ; ISSN 0960-894X

مصطلحات موضوعية: Organic Chemistry, Clinical Biochemistry, Drug Discovery, Pharmaceutical Science, Molecular Biology, Molecular Medicine, Biochemistry

الإتاحة: https://doi.org/10.1016/j.bmcl.2008.03.011Test
https://api.elsevier.com/content/article/PII:S0960894X08002758?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0960894X08002758?httpAccept=text/plainTest

المؤلفون: Goodwin, Michael B., Boshoff, Helena I., Barry, Clifton E., Dowd, Cynthia S.

المصدر: Rapid Communications in Mass Spectrometry ; volume 20, issue 22, page 3345-3350 ; ISSN 0951-4198 1097-0231

الإتاحة: https://doi.org/10.1002/rcm.2745Test

المؤلفون: Kim, Pilho, Zhang, Yong-Mei, Shenoy, Gautham, Nguyen, Quynh-Anh, Boshoff, Helena I., Manjunatha, Ujjini H., Goodwin, Michael B., Lonsdale, John, Price, Allen C., Miller, Darcie J., Duncan, Ken, White, Stephen W., Rock, Charles O., Barry, Clifton E., Dowd, Cynthia S.

المصدر: Journal of Medicinal Chemistry ; volume 49, issue 1, page 159-171 ; ISSN 0022-2623 1520-4804

الإتاحة: https://doi.org/10.1021/jm050825pTest

المؤلفون: Philana Ling Lin, Dartois, Véronique, Johnston, Paul J., Janssen, Christopher, Via, Laura, Goodwin, Michael B., Klein, Edwin, Barry III, Clifton E., Flynn, JoAnne L.

المصدر: Proceedings of the National Academy of Sciences of the United States of America; 8/28/2012, Vol. 109 Issue 35, p14188-14193, 6p

مصطلحات موضوعية: TUBERCULOSIS treatment, METRONIDAZOLE, MYCOBACTERIUM tuberculosis, MACAQUES, RIFAMPIN, CELLULAR pathology, TUMOR necrosis factors, HYPOXEMIA