المؤلفون: Li, Li-Hsin, Chiu, Winston, Huang, Yun-An, Rasulova, Madina, Vercruysse, Thomas, Thibaut, Hendrik Jan, ter Horst, Sebastiaan, Rocha-Pereira, Joana, Vanhoof, Greet, Borrenberghs, Doortje, Goethals, Olivia, Kaptein, Suzanne J. F., Leyssen, Pieter, Neyts, Johan, Dallmeier, Kai

المصدر: Nature Communications ; volume 15, issue 1 ; ISSN 2041-1723

مصطلحات موضوعية: General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Multidisciplinary

الإتاحة: https://doi.org/10.1038/s41467-023-44339-zTest
https://www.nature.com/articles/s41467-023-44339-z.pdfTest
https://www.nature.com/articles/s41467-023-44339-zTest

المؤلفون: Goethals, Olivia, Kaptein, Suzanne J F, Kesteleyn, Bart, Bonfanti, Jean-Francois, Van Wesenbeeck, Liesbeth, Bardiot, Dorothee, Verschoor, Ernst J, Verstrepen, Babs E, Fagrouch, Zahra, Putnak, J Robert, Kiemel, Dominik, Ackaert, Oliver, Straetemans, Roel, Lachau-Durand, Sophie, Geluykens, Peggy, Crabbe, Marjolein, Thys, Kim, Stoops, Bart, Lenz, Oliver, Tambuyzer, Lotke, De Meyer, Sandra, Dallmeier, Kai, McCracken, Michael K, Gromowski, Gregory D, Rutvisuttinunt, Wiriya, Jarman, Richard G, Karasavvas, Nicos, Touret, Franck, Querat, Gilles, de Lamballerie, Xavier, Chatel-Chaix, Laurent, Milligan, Gregg N, Beasley, David W C, Bourne, Nigel, Barrett, Alan D T, Marchand, Arnaud, Jonckers, Tim H M, Raboisson, Pierre, Simmen, Kenny, Chaltin, Patrick, Bartenschlager, Ralf, Bogers, Willy M, Neyts, Johan, Van Loock, Marnix

مصطلحات موضوعية: Drug discovery, Diseases

وصف الملف: application/pdf

العلاقة: https://espace.inrs.ca/id/eprint/13391/1/Blocking%20NS3-NS4B%20interaction%20inhibits%20dengue%20virus%20in%20non-human%20primates.pdfTest; Goethals, Olivia; Kaptein, Suzanne J F; Kesteleyn, Bart; Bonfanti, Jean-Francois; Van Wesenbeeck, Liesbeth; Bardiot, Dorothee; Verschoor, Ernst J; Verstrepen, Babs E; Fagrouch, Zahra; Putnak, J Robert; Kiemel, Dominik; Ackaert, Oliver; Straetemans, Roel; Lachau-Durand, Sophie; Geluykens, Peggy; Crabbe, Marjolein; Thys, Kim; Stoops, Bart; Lenz, Oliver; Tambuyzer, Lotke; De Meyer, Sandra; Dallmeier, Kai; McCracken, Michael K; Gromowski, Gregory D; Rutvisuttinunt, Wiriya; Jarman, Richard G; Karasavvas, Nicos; Touret, Franck; Querat, Gilles; de Lamballerie, Xavier; Chatel-Chaix, Laurent ORCID logoorcid:0000-0002-7390-8250; Milligan, Gregg N; Beasley, David W C; Bourne, Nigel; Barrett, Alan D T; Marchand, Arnaud; Jonckers, Tim H M; Raboisson, Pierre; Simmen, Kenny; Chaltin, Patrick; Bartenschlager, Ralf; Bogers, Willy M; Neyts, Johan et Van Loock, Marnix (2023). Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates Nature , vol. 615 , nº 7953. pp. 678-686. DOI:10.1038/s41586-023-05790-6 .

الإتاحة: https://doi.org/10.1038/s41586-023-05790-6Test
https://espace.inrs.ca/id/eprint/13391Test/
https://espace.inrs.ca/id/eprint/13391/1/Blocking%20NS3-NS4B%20interaction%20inhibits%20dengue%20virus%20in%20non-human%20primates.pdfTest
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033419Test/

المؤلفون: McCormack, Clare P., Goethals, Olivia, Goeyvaerts, Nele, Woot de Trixhe, Xavier D., Geluykens, Peggy, Borrenberghs, Doortje, Ferguson, Neil M., Ackaert, Oliver, Dorigatti, Ilaria

المساهمون: Perkins, Alex, Medical Research Council, Wellcome Trust, Royal Society, Agentschap Innoveren en Ondernemen

المصدر: PLOS Computational Biology ; volume 19, issue 12, page e1011662 ; ISSN 1553-7358

الإتاحة: https://doi.org/10.1371/journal.pcbi.1011662Test

المؤلفون: Goethals, Olivia, Voge, Natalia V., Kesteleyn, Bart, Chaltin, Patrick, Jinks, Tim, De Marez, Tine, Koul, Anil, Draghia-Akli, Ruxandra, Neyts, Johan, Van Loock, Marnix

المصدر: Antiviral Research ; volume 210, page 105495 ; ISSN 0166-3542

مصطلحات موضوعية: Virology, Pharmacology

الإتاحة: https://doi.org/10.1016/j.antiviral.2022.105495Test
https://api.elsevier.com/content/article/PII:S0166354222002649?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0166354222002649?httpAccept=text/plainTest

المؤلفون: Kesteleyn, Bart, Bonfanti, Jean-François, Bardiot, Dorothée, De Boeck, Benoît, Goethals, Olivia, Kaptein, Suzanne J. F., Stoops, Bart, Coesemans, Erwin, Fortin, Jérôme, Muller, Philippe, Doublet, Frédéric, Carlens, Gunter, Koukni, Mohamed, Smets, Wim, Raboisson, Pierre, Chaltin, Patrick, Simmen, Kenny, Loock, Marnix Van, Neyts, Johan, Marchand, Arnaud, Jonckers, Tim H. M.

المساهمون: Agentschap Innoveren en Ondernemen, Wellcome Trust

المصدر: Journal of Medicinal Chemistry ; volume 67, issue 5, page 4063-4082 ; ISSN 0022-2623 1520-4804

الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c02336Test

المؤلفون: Bifani, Amanda Makha, Chan, Kitti Wing Ki, Borrenberghs, Doortje, Tan, Min Jie Alvin, Phoo, Wint Wint, Watanabe, Satoru, Goethals, Olivia, Vasudevan, Subhash G., Choy, Milly M.

المساهمون: National Medical Research Council

المصدر: Antiviral Research ; volume 210, page 105517 ; ISSN 0166-3542

مصطلحات موضوعية: Virology, Pharmacology

الإتاحة: https://doi.org/10.1016/j.antiviral.2022.105517Test
https://api.elsevier.com/content/article/PII:S0166354222002868?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0166354222002868?httpAccept=text/plainTest

المؤلفون: Kesteleyn, Bart, Bardiot, Dorothée, Bonfanti, Jean-François, De Boeck, Benoît, Goethals, Olivia, Kaptein, Suzanne J. F., Stoops, Bart, Coesemans, Erwin, Fortin, Jérôme, Muller, Philippe, Doublet, Frédéric, Carlens, Gunter, Koukni, Mohamed, Smets, Wim, Raboisson, Pierre, Chaltin, Patrick, Simmen, Kenny, Van Loock, Marnix, Neyts, Johan, Marchand, Arnaud, Jonckers, Tim H. M.

المساهمون: Wellcome Trust

المصدر: Journal of Medicinal Chemistry ; volume 66, issue 13, page 8808-8821 ; ISSN 0022-2623 1520-4804

الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c00403Test

المؤلفون: Touret, Franck, Baronti, Cecile, Goethals, Olivia, van Loock, Marnix, de Lamballerie, Xavier, Quérat, Gilles

المساهمون: Infections Virales et Pathologie Comparée - UMR 754 (IVPC), Institut National de la Recherche Agronomique (INRA)-École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Unité des Virus Emergents (UVE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Janssen Infectious Diseases Discovery, Janssen Pharmaceutica N.V. Beerse, Belgium, Emergence des Pathologies Virales (EPV), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: ISSN: 0166-3542 ; Antiviral Research ; https://amu.hal.science/hal-02617069Test ; Antiviral Research, 2019, 168, pp.109-113. ⟨10.1016/j.antiviral.2019.05.005⟩.

مصطلحات موضوعية: [SDV]Life Sciences [q-bio]

العلاقة: hal-02617069; https://amu.hal.science/hal-02617069Test; https://amu.hal.science/hal-02617069/documentTest; https://amu.hal.science/hal-02617069/file/S0166354219301433.pdfTest; PII: S0166-3542(19)30143-3

الإتاحة: https://doi.org/10.1016/j.antiviral.2019.05.005Test
https://amu.hal.science/hal-02617069Test
https://amu.hal.science/hal-02617069/documentTest
https://amu.hal.science/hal-02617069/file/S0166354219301433.pdfTest

المؤلفون: Grosse, Sandrine, Tahri, Abdellah, Raboisson, Pierre, Houpis, Yannis, Stoops, Bart, Jacoby, Edgar, Neefs, Jean-Marc, Van Loock, Marnix, Goethals, Olivia, Geluykens, Peggy, Bonfanti, Jean-François, Jonckers, Tim H. M.

المصدر: ACS Medicinal Chemistry Letters ; volume 13, issue 12, page 1879-1884 ; ISSN 1948-5875 1948-5875

مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry

الإتاحة: https://doi.org/10.1021/acsmedchemlett.2c00372Test

المؤلفون: Kaptein, Suzanne J F, Goethals, Olivia, Kiemel, Dominik, Marchand, Arnaud, Kesteleyn, Bart, Bonfanti, Jean-Francois, Bardiot, Dorothee, Stoops, Bart, Jonckers, Tim H M, Dallmeier, Kei, Geluykens, Peggy, Thys, Kim, Crabbe, Marjolein, Chatel-Chaix, Laurent, Münster, May, Querat, Gilles, Touret, Franck, de Lamballerie, Xavier, Raboisson, Pierre, Simmen, Kenny, Chaltin, Patrick, Bartenschlager, Ralf, Van Loock, Marnix, Neyts, Johan

العلاقة: Kaptein, Suzanne J F, Goethals, Olivia, Kiemel, Dominik, Marchand, Arnaud, Kesteleyn, Bart, Bonfanti, Jean-Francois, Bardiot, Dorothee, Stoops, Bart, Jonckers, Tim H M, Dallmeier, Kei, Geluykens, Peggy, Thys, Kim, Crabbe, Marjolein, Chatel-Chaix, Laurent orcid:0000-0002-7390-8250 , Münster, May, Querat, Gilles, Touret, Franck, de Lamballerie, Xavier, Raboisson, Pierre, Simmen, Kenny, Chaltin, Patrick, Bartenschlager, Ralf, Van Loock, Marnix et Neyts, Johan (2021). A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction Nature , vol. 598 , nº 7881. p. 504-509. DOI:10.1038/s41586-021-03990-6 .

الإتاحة: https://doi.org/10.1038/s41586-021-03990-6Test
https://espace.inrs.ca/id/eprint/12360Test/