المؤلفون: Fink, Elissa A, Xu, Jun, Hübner, Harald, Braz, Joao M, Seemann, Philipp, Avet, Charlotte, Craik, Veronica, Weikert, Dorothee, Schmidt, Maximilian F, Webb, Chase M, Tolmachova, Nataliya A, Moroz, Yurii S, Huang, Xi-Ping, Kalyanaraman, Chakrapani, Gahbauer, Stefan, Chen, Geng, Liu, Zheng, Jacobson, Matthew P, Irwin, John J, Bouvier, Michel, Du, Yang, Shoichet, Brian K, Basbaum, Allan I, Gmeiner, Peter

المصدر: Science. 377(6614)

مصطلحات موضوعية: Adrenergic alpha-2 Receptor Agonists, Analgesics, Non-Narcotic, Animals, Dexmedetomidine, Drug Design, Drug Discovery, Humans, Ligands, Mice, Molecular Docking Simulation, Pain, Pain Management, Structure-Activity Relationship, Neurosciences, Pain Research, Chronic Pain, General Science & Technology

الوصول الحر: https://escholarship.org/uc/item/6r0990sdTest

المؤلفون: Lahmy, Ranit, Hübner, Harald, Gmeiner, Peter, König, Burkhard

المساهمون: Deutsche Forschungsgemeinschaft

المصدر: ChemPhotoChem ; ISSN 2367-0932 2367-0932

الإتاحة: https://doi.org/10.1002/cptc.202400022Test

المؤلفون: Sink, Alexandra, Gerwe, Hubert, Hübner, Harald, Boivin‐Jahns, Valerie, Fender, Julia, Lorenz, Kristina, Gmeiner, Peter, Decker, Michael

المساهمون: Deutsche Forschungsgemeinschaft, Elitenetzwerk Bayern, Studienstiftung des Deutschen Volkes

المصدر: Chemistry – A European Journal ; volume 30, issue 11 ; ISSN 0947-6539 1521-3765

الإتاحة: https://doi.org/10.1002/chem.202303506Test

المؤلفون: Chen, Geng, Staffen, Nico, Wu, Zhangsong, Xu, Xinyu, Pan, Jinheng, Inoue, Asuka, Shi, Tingyi, Gmeiner, Peter, Du, Yang, Xu, Jun

المساهمون: National Natural Science Foundation of China, Science, Technology and Innovation Commission of Shenzhen Municipality: a funding source from Shenzhe, Science, Technology and Innovation Commission of Shenzhen Municipality:a funding source from Shenzhe, Japan Agency for Medical Research and Development, Daiichi Sankyo Foundation of Life Science, MEXT | Japan Science and Technology Agency, MEXT | Japan Society for the Promotion of Science

المصدر: Cell Research ; ISSN 1748-7838

مصطلحات موضوعية: Cell Biology, Molecular Biology

الإتاحة: https://doi.org/10.1038/s41422-023-00919-8Test
https://www.nature.com/articles/s41422-023-00919-8.pdfTest
https://www.nature.com/articles/s41422-023-00919-8Test

المؤلفون: Sure, Florian, Einsiedel, Jürgen, Gmeiner, Peter, Duchstein, Patrick, Zahn, Dirk, Korbmacher, Christoph, Ilyaskin, Alexandr V.

المساهمون: Deutsche Forschungsgemeinschaft

المصدر: Journal of Biological Chemistry ; volume 300, issue 4, page 105785 ; ISSN 0021-9258

مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry

الإتاحة: https://doi.org/10.1016/j.jbc.2024.105785Test
https://api.elsevier.com/content/article/PII:S0021925824001613?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0021925824001613?httpAccept=text/plainTest

المؤلفون: Xu, Xinyu, Kaindl, Jonas, Clark, Mary J, Hübner, Harald, Hirata, Kunio, Sunahara, Roger K, Gmeiner, Peter, Kobilka, Brian K, Liu, Xiangyu

المصدر: Cell Research. 31(5)

مصطلحات موضوعية: Neurosciences, Underpinning research, 1.1 Normal biological development and functioning, Humans, Norepinephrine, Receptors, Adrenergic, beta-1, Biochemistry and Cell Biology, Clinical Sciences, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3b52v1wzTest

المؤلفون: Gmeiner, Peter

مصطلحات موضوعية: Statistics - Machine Learning, Computer Science - Information Theory, Computer Science - Machine Learning, stat.ML, cs.IT, cs.LG

الوصول الحر: http://arxiv.org/abs/2007.15047Test

المؤلفون: Panel, Nicolas, Vo, Duc Duy, Kahlous, Nour Aldin, Huebner, Harald, Tiedt, Stephanie, Matricon, Pierre, Pacalon, Jody, Fleetwood, Oliver, Kampen, Stefanie, Luttens, Andreas, 1993, Delemotte, Lucie, Kihlberg, Jan, Gmeiner, Peter, Carlsson, Jens

المصدر: Angewandte Chemie International Edition. 62(22)

مصطلحات موضوعية: Agonist, beta(2) Adrenergic Receptor, Drug Design, Free Energy Perturbation, G-Protein-Coupled Receptor, Molecular Dynamics

وصف الملف: electronic

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-524663Test
https://doi.org/10.1002/anie.202218959Test
https://uu.diva-portal.org/smash/get/diva2:1844020/FULLTEXT01.pdfTest

المؤلفون: Liu, Xiangyu, Kaindl, Jonas, Korczynska, Magdalena, Stößel, Anne, Dengler, Daniela, Stanek, Markus, Hübner, Harald, Clark, Mary J, Mahoney, Jake, Matt, Rachel Ann, Xu, Xinyu, Hirata, Kunio, Shoichet, Brian K, Sunahara, Roger K, Kobilka, Brian K, Gmeiner, Peter

المصدر: Nature chemical biology. 16(7)

مصطلحات موضوعية: Humans, Water, Norepinephrine, Alprenolol, Receptors, Adrenergic, beta-2, Adrenergic beta-Antagonists, Ligands, Allosteric Regulation, Allosteric Site, Protein Structure, Secondary, Protein Binding, Kinetics, Thermodynamics, Protein Interaction Domains and Motifs, Molecular Dynamics Simulation, HEK293 Cells, Adrenergic beta-2 Receptor Agonists, Molecular Docking Simulation, Salmeterol Xinafoate, Underpinning research, 1.1 Normal biological development and functioning, Medicinal and Biomolecular Chemistry, Biochemistry and Cell Biology, Biochemistry & Molecular Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9923t98rTest

المؤلفون: Bathe-Peters, Marc, Gmach, Philipp, Boltz, Horst-Holger, Einsiedel, Jürgen, Gotthardt, Michael, Hübner, Harald, Gmeiner, Peter, Lohse, Martin J., Annibale, Paolo

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2021 Jun 01. 118(23), 1-10.

الوصول الحر: https://www.jstor.org/stable/27040921Test