المؤلفون: Schmidt, Andreas, Armento, Angela, Bussolati, Ovidio, Chiu, Martina, Ellerkamp, Verena, Scharpf, Marcus O., Sander, Philip, Schmid, Evi, Warmann, Steven W., Fuchs, Jörg

المصدر: http://lobid.org/resources/99370674181806441Test#!, 147(11):3169-3181.

مصطلحات موضوعية: Cell Line, Tumor [MeSH], Gene Expression [MeSH], beta Catenin/genetics [MeSH], Liver Neoplasms/pathology [MeSH], Liver Neoplasms/metabolism [MeSH], Exons [MeSH], Hepatoblastoma/genetics [MeSH], Liver Neoplasms/genetics [MeSH], Hepatoblastoma/metabolism [MeSH], Asparaginase, Mutation [MeSH], Original Article – Cancer Research, Humans [MeSH], Hepatocellular carcinoma, Glutamine/metabolism [MeSH], Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor/biosynthesis [MeSH], Hepatoblastoma/pathology [MeSH], Glutamine/deficiency [MeSH], Glutamate-Ammonia Ligase/genetics [MeSH], Cell Survival/physiology [MeSH], Glutamine synthetase, Asparagine synthetase, Glutamine depletion, Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor/genetics [MeSH], Glutamate-Ammonia Ligase/biosynthesis [MeSH], Hepatoblastoma

العلاقة: https://repository.publisso.de/resource/frl:6449842Test; https://doi.org/10.1007/s00432-021-03713-4Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484192Test/

الإتاحة: https://doi.org/10.1007/s00432-021-03713-4Test
https://repository.publisso.de/resource/frl:6449842Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484192Test/

المؤلفون: Meunier, C., Merienne, N., Jollé, C., Déglon, N., Pellerin, L.

المصدر: Glia, vol. 64, no. 11, pp. 1841-1856

مصطلحات موضوعية: Animals, Astrocytes/metabolism, Astrocytes/pathology, Brain/pathology, Cyclophilin A/metabolism, Disease Models, Animal, Dopamine and cAMP-Regulated Phosphoprotein 32/metabolism, Gene Expression Regulation/genetics, Glial Fibrillary Acidic Protein/metabolism, Glutamate-Ammonia Ligase/genetics, Glutamate-Ammonia Ligase/metabolism, Glutamic Acid/metabolism, Glutamine/metabolism, Humans, Huntingtin Protein/genetics, Huntingtin Protein/metabolism, Huntington Disease/complications, Huntington Disease/genetics, Huntington Disease/pathology, Locomotion/genetics, Locomotion/physiology, Mice, Transgenic, Mutation/genetics, Nerve Tissue Proteins/metabolism, Neurons/pathology, Nuclear Proteins/metabolism, adenoassociated viral vectors, glia

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/27442486; info:eu-repo/semantics/altIdentifier/eissn/1098-1136; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_CCF30D345F548; https://serval.unil.ch/notice/serval:BIB_CCF30D345F54Test; urn:issn:0894-1491; https://serval.unil.ch/resource/serval:BIB_CCF30D345F54.P003/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_CCF30D345F548Test

الإتاحة: https://doi.org/10.1002/glia.23022Test
https://serval.unil.ch/notice/serval:BIB_CCF30D345F54Test
https://serval.unil.ch/resource/serval:BIB_CCF30D345F54.P003/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_CCF30D345F548Test

المؤلفون: Vishnu Sharma, Sushma Singh, Prabha Garg, Vinay Kumar, Neha Tripathi, N. Sushma Sri, Prasad V. Bharatam

المساهمون: Thapar Institute of Engineering and Technology, Chimie Et Interdisciplinarité : Synthèse, Analyse, Modélisation (CEISAM), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)

المصدر: International Journal of Biological Macromolecules
International Journal of Biological Macromolecules, Elsevier, 2020, 146, pp.860-874. ⟨10.1016/j.ijbiomac.2019.09.209⟩

مصطلحات موضوعية: MESH: Catalytic Domain Computer Simulation* Fluorescence Glutamate-Ammonia Ligase / chemistry* Glutamate-Ammonia Ligase / genetics Glutamate-Ammonia Ligase / isolation & purification Kinetics Leishmania donovani / enzymology* Molecular Docking Simulation Mutation / genetics Protein Structure, Secondary Recombinant Proteins / metabolism Structural Homology, Protein Thermodynamics, [SDV]Life Sciences [q-bio], In silico, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, 02 engineering and technology, Biochemistry, Fluorescence, Protein Structure, Secondary, Glutamine synthetase, 03 medical and health sciences, Glutamate-Ammonia Ligase, Structural Biology, Catalytic Domain, Alanine scanning, Computer Simulation, Site-directed mutagenesis, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Virtual screening, biology, Active site, General Medicine, 021001 nanoscience & nanotechnology, Recombinant Proteins, Protein tertiary structure, Amino acid, Molecular Docking Simulation, Kinetics, chemistry, Structural Homology, Protein, Mutation, biology.protein, Thermodynamics, Homology modelling, 0210 nano-technology, Leishmania donovani

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bcd85e1d15a7a37157350cdf0c29816Test
https://doi.org/10.1016/j.ijbiomac.2019.09.209Test

المؤلفون: Kumar, Vinay, Sushma Sri, N., Tripathi, Neha, Sharma, Vishnu, Bharatam, Prasad, Garg, Prabha, Singh, Sushma

المساهمون: Thapar Institute of Engineering and Technology Patiala, Inde (TIET), Chimie Et Interdisciplinarité : Synthèse, Analyse, Modélisation (CEISAM), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)

المصدر: ISSN: 0141-8130 ; International Journal of Biological Macromolecules ; https://hal.science/hal-03416460Test ; International Journal of Biological Macromolecules, 2020, 146, pp.860-874. ⟨10.1016/j.ijbiomac.2019.09.209⟩.

مصطلحات موضوعية: Alanine scanning, Glutamine synthetase, Homology modelling, MESH: Catalytic Domain Computer Simulation* Fluorescence Glutamate-Ammonia Ligase / chemistry* Glutamate-Ammonia Ligase / genetics Glutamate-Ammonia Ligase / isolation & purification Kinetics Leishmania donovani / enzymology* Molecular Docking Simulation Mutation / genetics Protein Structure, Secondary Recombinant Proteins / metabolism Structural Homology, Protein Thermodynamics, [SDV]Life Sciences [q-bio], [SDV.BC]Life Sciences [q-bio]/Cellular Biology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/31726137; hal-03416460; https://hal.science/hal-03416460Test; PUBMED: 31726137

الإتاحة: https://doi.org/10.1016/j.ijbiomac.2019.09.209Test
https://hal.science/hal-03416460Test

المؤلفون: Gijs van Haaften, Nanda M. Verhoeven-Duif, Marjo S. van der Knaap, Holger Rehmann, Graeme C.M. Black, Jeroen Bakkers, Lynne Rumping, Peter M. van Hasselt, Hester Y. Kroes, Ruben Ramos, Tobias B. Dansen, Hubertus C.M.T. Prinsen, Sanne M C Savelberg, Judith J.M. Jans, Dennis W. J. Klomp, Rachel L. Taylor, Alex A. Bhogal, Esmee Vringer, Federico Tessadori, Jannie P. Wijnen, Peter A W J F Schellekens, Mark J.G. Bakkers, Fried J. T. Zwartkruis, Petra J. W. Pouwels, Roderick H. J. Houwen, Karen Duran

المساهمون: ARD - Amsterdam Reproduction and Development, Hubrecht Institute for Developmental Biology and Stem Cell Research, Radiology and nuclear medicine, Amsterdam Neuroscience - Cellular & Molecular Mechanisms, Amsterdam Reproduction & Development (AR&D), Pediatric surgery

المصدر: Taylor, R L & Black, G 2019, ' GLS hyperactivity causes glutamate excess, infantile cataract and profound developmental delay ', Human Molecular Genetics, vol. 28, no. 1, pp. 96-104 . https://doi.org/10.1093/hmg/ddy330Test
Rumping, L, Tessadori, F, Pouwels, P J W, Vringer, E, Wijnen, J P, Bhogal, A A, Savelberg, S M C, Duran, K J, Bakkers, M J G, Ramos, R B J J, Schellekens, P A W, Kroes, H Y, Klomp, D W J, Black, G C M, Taylor, R L, Bakkers, J P W, Prinsen, H C M T, van der Knaap, M S, Dansen, T B, Rehmann, H, Zwartkruis, F J T, Houwen, R H J, van Haaften, G, Verhoeven-Duif, N M, Jans, J J M & van Hasselt, P M 2019, ' GLS hyperactivity causes glutamate excess, infantile cataract and profound developmental delay ', Human Molecular Genetics, vol. 28, no. 1, pp. 96-104 . https://doi.org/10.1093/hmg/ddy330Test
Human molecular genetics, 28(1), 96-104. Oxford University Press
Human Molecular Genetics. Oxford University Press
Human Molecular Genetics, 28(1), 96-104. Oxford University Press
Human Molecular Genetics, 28(1), 96. Oxford University Press

مصطلحات موضوعية: Male, GLS, Developmental Disabilities, Glutamine, medicine.disease_cause, loss-of-function, Glutamate homeostasis, Genetics(clinical), Child, Genetics (clinical), Zebrafish, 0303 health sciences, Glutaminase, 030305 genetics & heredity, Glutamate receptor, Brain, General Medicine, Cataract/genetics, Glutaminase/genetics, Glutamic Acid/genetics, Glutamine/metabolism, cataract, Gain of Function Mutation, Child, Preschool, Female, medicine.medical_specialty, Gain of Function Mutation/genetics, Adolescent, Glutamic Acid, Biology, Cataract, Glutamine synthetase, 03 medical and health sciences, Downregulation and upregulation, Glutamate-Ammonia Ligase, Reactive Oxygen Species/metabolism, Internal medicine, medicine, Glutamate-Ammonia Ligase/genetics, Genetics, Animals, Brain/metabolism, Humans, Gain-of-function, Preschool, Molecular Biology, Animal, Neurotoxicity, Fibroblasts, medicine.disease, Disease Models, Animal, Oxidative Stress, Endocrinology, HEK293 Cells, Disease Models, Reactive Oxygen Species, Oxidative stress, Developmental Disabilities/genetics

وصف الملف: application/pdf; image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa4edf932c3eefca85db219883f75f1Test
https://doi.org/10.1093/hmg/ddy330Test

المؤلفون: Tardito, Saverio, Oudin, Anaïs, Ahmed, Shafiq U, Fack, Fred, Keunen, Olivier, Zheng, Liang, Miletic, Hrvoje, Sakariassen, Per Øystein, Weinstock, Adam, Wagner, Allon, Lindsay, Susan L, Hock, Andreas K, Barnett, Susan C, Ruppin, Eytan, Mørkve, Svein Harald, Lund-Johansen, Morten, Chalmers, Anthony J, Bjerkvig, Rolf, NICLOU, Simone P., Gottlieb, Eyal

المصدر: Nature Cell Biology, 17 (12), 1556 - 1568 (2015-12)

مصطلحات موضوعية: Nucleotides, Glutamine, Glutamic Acid, Glutamate-Ammonia Ligase, Animals, Astrocytes/cytology, Astrocytes/metabolism, Blotting, Western, Brain Neoplasms/genetics, Brain Neoplasms/metabolism, Brain Neoplasms/pathology, Cell Line, Tumor, Cells, Cultured, Citric Acid Cycle, Coculture Techniques, Female, Glioblastoma/genetics, Glioblastoma/metabolism, Glioblastoma/pathology, Glutamate-Ammonia Ligase/genetics, Glutamate-Ammonia Ligase/metabolism, Glutamic Acid/metabolism, Glutamine/metabolism, Humans, Male, Mice, Inbred NOD

العلاقة: http://www.nature.com/articles/ncb3272.pdfTest; urn:issn:1465-7392; urn:issn:1476-4679; https://orbilu.uni.lu/handle/10993/60197Test; info:hdl:10993/60197; scopus-id:2-s2.0-84948701108; info:pmid:26595383; wos:000365932300008

الإتاحة: https://doi.org/10.1038/ncb3272Test
https://orbilu.uni.lu/handle/10993/60197Test

المؤلفون: Benoit Terris, Muriel Infante, Jean-François Fléjou, Alain Sauvanet, Catherine Cavard, François Paye, Anne Couvelard, Hubert Richa, Virginie Audard

المصدر: Pancreas, Vol. 36, No 1 (2008) pp. 80-83

مصطلحات موضوعية: Adult, Male, Cytoplasm, Carcinoma, Pancreatic Ductal/chemistry/genetics, Cyclin D1/genetics, Gene Expression, Endocrinology, Diabetes and Metabolism, DNA Mutational Analysis, Cadherins/analysis/*genetics, ddc:616.07, Cell Membrane/chemistry, Biology, Glutamate-Ammonia Ligase/*genetics, Pancreatic Neoplasms/chemistry/*genetics, Endocrinology, Cyclin D1, Glutamate-Ammonia Ligase, Glutamine synthetase, Gene expression, Internal Medicine, medicine, Humans, Wnt Proteins/physiology, beta Catenin, Hepatology, Reverse Transcriptase Polymerase Chain Reaction, Cadherin, Cell Membrane, Wnt signaling pathway, Cadherins, Immunohistochemistry, Pancreatic Neoplasms, Wnt Proteins, medicine.anatomical_structure, Beta Catenin/analysis/physiology, Cancer research, Female, Signal transduction, Pancreas, Cytoplasm/chemistry, Carcinoma, Pancreatic Ductal, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ea4001d8c6be815cd187ba6d895f48Test
https://doi.org/10.1097/mpa.0b013e318137a9daTest

المؤلفون: Audard, Virginie, Cavard, Catherine, Richa, Hubert, Genevay-Infante, Muriel, Couvelard, Anne, Sauvanet, Alain, Terris, Benoit, Paye, Francois, Flejou, Jean-Francois

المصدر: ISSN: 0885-3177 ; Pancreas, vol. 36, no. 1 (2008) p. 80-83.

مصطلحات موضوعية: info:eu-repo/classification/ddc/616.07, Adult, Cadherins/analysis/*genetics, Carcinoma, Pancreatic Ductal/chemistry/genetics, Cell Membrane/chemistry, Cyclin D1/genetics, Cytoplasm/chemistry, DNA Mutational Analysis, Female, Gene Expression, Glutamate-Ammonia Ligase/*genetics, Humans, Immunohistochemistry, Male, Pancreatic Neoplasms/chemistry/*genetics, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction, Wnt Proteins/physiology, Beta Catenin/analysis/physiology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/18192886; https://archive-ouverte.unige.ch/unige:19620Test; unige:19620

الإتاحة: https://doi.org/10.1097/mpa.0b013e318137a9daTest
https://archive-ouverte.unige.ch/unige:19620Test

المؤلفون: Zurich, M.G., Lengacher, S., Braissant, O., Monnet-Tschudi, F., Pellerin, L., Honegger, P.

المصدر: Neuroscience, vol. 134, no. 3, pp. 771-782

مصطلحات موضوعية: Animals, Astrocytes/drug effects, Astrocytes/physiology, Brain/cytology, Cell Aggregation/drug effects, Cells, Cultured, Culture Media, Serum-Free/pharmacology, Cyclic AMP/metabolism, Cyclic AMP/pharmacology, Dose-Response Relationship, Drug, Drug Interactions, Embryo, Mammalian, Extracellular Fluid/drug effects, Extracellular Fluid/metabolism, Gene Expression Regulation/drug effects, Glial Fibrillary Acidic Protein/genetics, Glial Fibrillary Acidic Protein/metabolism, Glutamate-Ammonia Ligase/genetics, Glutamate-Ammonia Ligase/metabolism, Heme Oxygenase (Decyclizing)/genetics, Heme Oxygenase (Decyclizing)/metabolism, Heme Oxygenase-1, Hydro-Lyases/metabolism, Immunohistochemistry/methods, In Situ Hybridization/methods, Mycotoxins/pharmacology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/15994020; info:eu-repo/semantics/altIdentifier/pissn/0306-4522[print], 0306-4522[linking]; https://serval.unil.ch/notice/serval:BIB_35682Test

الإتاحة: https://doi.org/10.1016/j.neuroscience.2005.04.030Test
https://serval.unil.ch/notice/serval:BIB_35682Test

المؤلفون: Legrain, Christiane, Vissers, S, Dubois, Evelyne, Legrain, M, Wiame, Jean-Marie

المصدر: European journal of biochemistry / FEBS, 123 (3

مصطلحات موضوعية: Sciences bio-médicales et agricoles, Glutamate-Ammonia Ligase -- antagonists & inhibitors, Glutamate-Ammonia Ligase -- genetics, Glutamate-Ammonia Ligase -- physiology, Mutation, Nitrogen -- pharmacology, Saccharomyces cerevisiae -- enzymology

وصف الملف: No full-text files

العلاقة: uri/info:pmid/6122575; uri/info:scp/0020033683; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/50041Test

الإتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/50041Test