التفاصيل البيبلوغرافية
| العنوان: |
Neoadjuvant Approaches to Non-Melanoma Skin Cancer. |
| المؤلفون: |
Wilde, David C.1 (AUTHOR), Glaun, Mica E.2 (AUTHOR), Wong, Michael K.3 (AUTHOR) mkwong@mdanderson.org, Gross, Neil D.2 (AUTHOR) ngross@mdanderson.org |
| المصدر: |
Cancers. Dec2023, Vol. 15 Issue 23, p5494. 10p. |
| مصطلحات موضوعية: |
*SKIN diseases, *FUNCTIONAL status, *SKIN tumors, *QUALITY of life, *COMBINED modality therapy, *MERKEL cell carcinoma, *BASAL cell carcinoma, *IMMUNOTHERAPY, *SQUAMOUS cell carcinoma |
| مستخلص: |
Simple Summary: Non-melanomatous skin cancer (NMSC) is the most incident malignancy worldwide, and management can be difficult in the locally advanced setting. Here, we examine the literature on the use of neoadjuvant systemic therapy prior to surgical excision of NMSC. Surgery and external-beam radiation therapy are the primary treatment modalities for locally advanced NMSC, but they can lead to impairment of function and disfigurement in sensitive areas such as the head and neck. With the advent of targeted systemic therapies and immunotherapy, physicians have explored the ability to offer neoadjuvant therapy for NMSC in order to reduce surgically induced morbidity. Provided herein is a guide to current applications of neoadjuvant systemic therapies for NMSC and future directions. [ABSTRACT FROM AUTHOR] |
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