المؤلفون: Ziva Pogacar, Jackie L Johnson, Lenno Krenning, Giulia De Conti, Fleur Jochems, Cor Lieftink, Arno Velds, Leyma Wardak, Kelvin Groot, Arnout Schepers, Liqin Wang, Ji-Ying Song, Marieke van de Ven, Olaf van Tellingen, Rene H Medema, Roderick L Beijersbergen, Rene Bernards, Rodrigo Leite de Oliveira

المصدر: PLoS ONE, Vol 17, Iss 9, p e0273182 (2022)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1932-6203Test

الوصول الحر: https://doaj.org/article/6f29ef7b9b734b128186d1949fb65c09Test

المؤلفون: Fleur Jochems, Bram Thijssen, Giulia De Conti, Robin Jansen, Ziva Pogacar, Kelvin Groot, Liqin Wang, Arnout Schepers, Cun Wang, Haojie Jin, Roderick L. Beijersbergen, Rodrigo Leite de Oliveira, Lodewyk F.A. Wessels, René Bernards

المصدر: Cell Reports, Vol 36, Iss 4, Pp 109441- (2021)

مصطلحات موضوعية: senescence, cancer, ABT-263, gene expression classifier, transcriptome profiling, senolytics, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2211124721008585Test; https://doaj.org/toc/2211-1247Test

الوصول الحر: https://doaj.org/article/e5885b546531426bb7c25ec795372518Test

المؤلفون: Giulia De Conti, Matheus Henrique Dias, René Bernards

المصدر: Cancers, Vol 13, Iss 5, p 1118 (2021)

مصطلحات موضوعية: drug tolerance, cellular plasticity, adaptive resistance, collateral vulnerability, stress response, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/2072-6694/13/5/1118Test; https://doaj.org/toc/2072-6694Test

الوصول الحر: https://doaj.org/article/3b762ed69f7c47fd8229d3dfda206c68Test

المؤلفون: Giulia De Conti, Alicja M. Gruszka, Debora Valli, Andrea Umberto Cammarata, Matteo Righi, Massimiliano Mazza, Pier Giuseppe Pelicci

المصدر: Cancers, Vol 12, Iss 12, p 3768 (2020)

مصطلحات موضوعية: AML, mouse model, candidate genes, PML-RAR, AML1-ETO, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/2072-6694/12/12/3768Test; https://doaj.org/toc/2072-6694Test

الوصول الحر: https://doaj.org/article/55fafb28dbc14f79b893b567e7b1335cTest

المؤلفون: Matheus Henrique Dias, Anoek Friskes, Siying Wang, Joao M. Fernandes Neto, Frank van Gemert, Soufiane Mourragui, Hendrik J. Kuiken, Sara Mainardi, Daniel Alvarez-Villanueva, Cor Lieftink, Ben Morris, Anna Dekker, Emma van Dijk, Chrysa Papagianni, Marcelo S. da Silva, Robin Jansen, Antonio Mulero-Sánchez, Elke Malzer, August Vidal, Cristina Santos, Ramón Salazar, Rosangela A. M. Wailemann, Thompson E. P. Torres, Giulia De Conti, Jonne A. Raaijmakers, Petur Snaebjornsson, Shengxian Yuan, Wenxin Qin, John S. Kovach, Hugo A. Armelin, Hein te Riele, Alexander van Oudenaarden, Haojie Jin, Roderick L. Beijersbergen, Alberto Villanueva, Rene H. Medema, Rene Bernards

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::7a1e3875a49631c0a488ddbe547c772bTest
https://doi.org/10.1101/2023.02.06.527335Test

المؤلفون: Liqin Wang, Haojie Jin, Fleur Jochems, Siying Wang, Cor Lieftink, Isabel Mora Martinez, Giulia De Conti, Finn Edwards, Rodrigo Leite de Oliveira, Arnout Schepers, Yangyang Zhou, Jiaojiao Zheng, Wei Wu, Xingling Zheng, Shengxian Yuan, Jing Ling, Kathy Jastrzebski, Matheus Dos Santos Dias, Ji-Ying Song, Patrick N. H. Celie, Hideo Yagita, Ming Yao, Weiping Zhou, Roderick L. Beijersbergen, Wenxin Qin, René Bernards

المساهمون: Human genetics

المصدر: Nature Cancer, 3(11), 1284-1299. Nature Research
Wang, L, Jin, H, Jochems, F, Wang, S, Lieftink, C, Martinez, I M, de Conti, G, Edwards, F, de Oliveira, R L, Schepers, A, Zhou, Y, Zheng, J, Wu, W, Zheng, X, Yuan, S, Ling, J, Jastrzebski, K, Santos Dias, M D, Song, J-Y, Celie, P N H, Yagita, H, Yao, M, Zhou, W, Beijersbergen, R L, Qin, W & Bernards, R 2022, ' cFLIP suppression and DR5 activation sensitize senescent cancer cells to senolysis ', Nature Cancer, vol. 3, no. 11, pp. 1284-1299 . https://doi.org/10.1038/s43018-022-00462-2Test

مصطلحات موضوعية: Cancer Research, Oncology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a515cd48bd69c79c04ef44ba3703733Test
https://research.vumc.nl/en/publications/5cb78c17-95c0-4a56-91e6-59542f1c1a54Test

المؤلفون: René Bernards, Giulia De Conti, Lenno Krenning, Ziva Pogacar, Marieke van de Ven, Cor Lieftink, Arnout Schepers, Jackie Johnson, Arno Velds, Olaf van Tellingen, Kelvin Groot, Roderick L. Beijersbergen, Rodrigo Leite de Oliveira, Ji-Ying Song, Fleur Jochems, René H. Medema, Leyma Wardak, Liqin Wang

المساهمون: Human genetics

المصدر: PLoS ONE, 17(9 September):e0273182. Public Library of Science
Pogacar, Z, Johnson, J L, Krenning, L, de Conti, G, Jochems, F, Lieftink, C, Velds, A, Wardak, L, Groot, K, Schepers, A, Wang, L, Song, J-Y, van de Ven, M, van Tellingen, O, Medema, R H, Beijersbergen, R L, Bernards, R & Leite de Oliveira, R 2022, ' Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity ', PLoS ONE, vol. 17, no. 9 September, e0273182, pp. e0273182 . https://doi.org/10.1371/journal.pone.0273182Test

مصطلحات موضوعية: Senescence, Sulfonamides, Multidisciplinary, biology, Chemistry, Pyridines, Cyclin-dependent kinase 2, Cyclin-Dependent Kinase 2, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6, Palbociclib, Piperazines, Downregulation and upregulation, Cell culture, Cell Line, Tumor, Cancer cell, Cancer research, biology.protein, Humans, biological phenomena, cell phenomena, and immunity, Kinase activity, Senolytic, Protein Kinase Inhibitors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a29ef97e9ee3d0ca0f36662417d453aTest
http://www.scopus.com/inward/record.url?scp=85137745306&partnerID=8YFLogxKTest

المؤلفون: Cecilia Restelli, Giulia De Conti, Roman Hillje, Andrea Polazzi, Maria Elena Boggio Merlo, Giorgio Melloni, Lucilla Luzi, Emanuela Colombo, Pier Guiseppe Pelicci

المصدر: Blood. 140:1279-1280

مصطلحات موضوعية: Immunology, Cell Biology, Hematology, Biochemistry

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c25aaa91409b9483b70b27f96fd75577Test
https://doi.org/10.1182/blood-2022-158884Test

المؤلفون: Rodrigo Leite de Oliveira, Giulia De Conti, Cor Lieftink, Arnout Schepers, Roderick L. Beijersbergen, René Bernards, Ziva Pogacar, Fleur Jochems, Liqin Wang

المصدر: Mol Cancer Res

مصطلحات موضوعية: Senescence, Cancer Research, Autophagy-Related Proteins, Apoptosis, Biology, Article, Cell Line, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Neoplasms, Autophagy, medicine, Autophagy-Related Protein-1 Homolog, Humans, CRISPR, Senolytic, Molecular Biology, Cellular Senescence, Cell Proliferation, 030304 developmental biology, 0303 health sciences, Cancer, ULK1, medicine.disease, HEK293 Cells, Oncology, A549 Cells, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, CRISPR-Cas Systems

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eab7c3c161e6fd4bc1fdc9b4e06ac955Test
https://doi.org/10.1158/1541-7786.mcr-21-0146Test

المؤلفون: Ziva Pogacar, Kelvin Groot, Fleur Jochems, Matheus Dos Santos Dias, Ben Morris, Mieke Roosen, Leyma Wardak, Giulia De Conti, Arno Velds, Cor Lieftink, Roderick L. Beijersbergen, René Bernards, Rodrigo Leite de Oliveira

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::07406f3dd0e5b275179fb50e99060e7bTest
https://doi.org/10.1101/2021.12.20.473451Test