المؤلفون: Myers S. H., Poppi L., Rinaldi F., Veronesi M., Ciamarone A., Previtali V., Bagnolini G., Schipani F., Ortega Martínez J. A., Girotto S., Di Stefano G., Farabegoli F., Walsh N., De Franco F., Roberti M., Cavalli A.

المساهمون: Myers S. H., Poppi L., Rinaldi F., Veronesi M., Ciamarone A., Previtali V., Bagnolini G., Schipani F., Ortega Martínez J. A., Girotto S., Di Stefano G., Farabegoli F., Walsh N., De Franco F., Roberti M., Cavalli A.

مصطلحات موضوعية: Synthetic lethality, BRCA2-RAD51, PARP inhibition, NMR fragment-based screening, Pancreatic cancer

وصف الملف: ELETTRONICO

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/38194775; info:eu-repo/semantics/altIdentifier/wos/WOS:001154470700001; volume:265; firstpage:1; lastpage:20; numberofpages:20; journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY; https://hdl.handle.net/11585/952437Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85181920511

الإتاحة: https://doi.org/10.1016/j.ejmech.2023.116114Test
https://hdl.handle.net/11585/952437Test

المؤلفون: Rinaldi F., Schipani F., Balboni B., Catalano F., Marotta R., Myers S. H., Previtali V., Veronesi M., Scietti L., Cecatiello V., Pasqualato S., Ortega J. A., Girotto S., Cavalli A.

المساهمون: Rinaldi F., Schipani F., Balboni B., Catalano F., Marotta R., Myers S. H., Previtali V., Veronesi M., Scietti L., Cecatiello V., Pasqualato S., Ortega J. A., Girotto S., Cavalli A.

مصطلحات موضوعية: DNA damage, Protein engineering, Protein-protein interactions, Synthetic Lethality, Structural Biology

وصف الملف: ELETTRONICO

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37924230; volume:1; firstpage:1; lastpage:13; numberofpages:13; journal:ANGEWANDTE CHEMIE. INTERNATIONAL EDITION; https://hdl.handle.net/11585/947693Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85177080350

الإتاحة: https://doi.org/10.1002/anie.202312517Test
https://hdl.handle.net/11585/947693Test

المؤلفون: Balboni B., Rinaldi F., Previtali V., Ciamarone A., Girotto S., Cavalli A.

المساهمون: Balboni B., Rinaldi F., Previtali V., Ciamarone A., Girotto S., Cavalli A.

مصطلحات موضوعية: RAD52, synthetic lethality, precision medicine, drug discovery

وصف الملف: ELETTRONICO

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36980703; info:eu-repo/semantics/altIdentifier/wos/WOS:000957377100001; volume:15; issue:6; firstpage:1817; lastpage:1818; numberofpages:2; journal:CANCERS; https://hdl.handle.net/11585/922292Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85151487073; https://www.mdpi.com/2072-6694/15/6/1817Test

الإتاحة: https://doi.org/10.3390/cancers15061817Test
https://hdl.handle.net/11585/922292Test
https://www.mdpi.com/2072-6694/15/6/1817Test

المؤلفون: Bagnolini, G., Balboni, B., Schipani, F., Gioia, D., Veronesi, M., De Franco, F., Kaya, C., Jumde, R. P., Ortega, J. A., Girotto, S., Hirsch, A. K. H., Roberti, M., Cavalli, A.

المساهمون: Bagnolini, G., Balboni, B., Schipani, F., Gioia, D., Veronesi, M., De Franco, F., Kaya, C., Jumde, R. P., Ortega, J. A., Girotto, S., Hirsch, A. K. H., Roberti, M., Cavalli, A.

مصطلحات موضوعية: DNA repair, hit-identification strategy, protein-protein interaction inhibitor, ptDCC, RAD51

وصف الملف: ELETTRONICO

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35978685; info:eu-repo/semantics/altIdentifier/wos/WOS:000893215900001; volume:13; issue:8; firstpage:1262; lastpage:1269; numberofpages:8; journal:ACS MEDICINAL CHEMISTRY LETTERS; https://hdl.handle.net/11585/901007Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85136146670

الإتاحة: https://doi.org/10.1021/acsmedchemlett.2c00063Test
https://hdl.handle.net/11585/901007Test

المؤلفون: Barbieri F., Bosio A. G., Pattarozzi A., Tonelli M., Bajetto A., Verduci I., Cianci F., Cannavale G., Palloni L. M. G., Francesconi V., Thellung S., Fiaschi P., Mazzetti S., Schenone S., Balboni B., Girotto S., Malatesta P., Daga A., Zona G., Mazzanti M., Florio T.

المساهمون: F. Barbieri, A.G. Bosio, A. Pattarozzi, M. Tonelli, A. Bajetto, I. Verduci, F. Cianci, G. Cannavale, L.M.G. Palloni, V. Francesconi, S. Thellung, P. Fiaschi, S. Mazzetti, S. Schenone, B. Balboni, S. Girotto, P. Malatesta, A. Daga, G. Zona, M. Mazzanti, T. Florio

مصطلحات موضوعية: Biguanide derivative, CLIC1, GBM organoid, Glioblastoma stem cell, Targeted therapy, Settore BIO/09 - Fisiologia, Settore BIO/14 - Farmacologia

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35135603; info:eu-repo/semantics/altIdentifier/wos/WOS:000752968200001; volume:41; issue:1; firstpage:1; lastpage:27; numberofpages:27; journal:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH; http://hdl.handle.net/2434/911224Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85124287258

الإتاحة: https://doi.org/10.1186/s13046-021-02213-0Test
http://hdl.handle.net/2434/911224Test

المؤلفون: Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A.

المساهمون: Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A.

مصطلحات موضوعية: BRCA2, RAD51, BRC repeats, SAXS

وصف الملف: STAMPA

العلاقة: ispartofbook:EMBO Workshop: Computational structural biology; EMBO Workshop: Computational structural biology; https://hdl.handle.net/11585/950003Test

الإتاحة: https://hdl.handle.net/11585/950003Test

المؤلفون: Bagnolini G., Milano D., Manerba M., Schipani F., Ortega J. A., Gioia D., Falchi F., Balboni A., Farabegoli F., De Franco F., Robertson J., Pellicciari R., Pallavicini I., Peri S., Minucci S., Girotto S., Di Stefano G., Roberti M., Cavalli A.

المساهمون: Bagnolini G., Milano D., Manerba M., Schipani F., Ortega J.A., Gioia D., Falchi F., Balboni A., Farabegoli F., De Franco F., Robertson J., Pellicciari R., Pallavicini I., Peri S., Minucci S., Girotto S., Di Stefano G., Roberti M., Cavalli A.

مصطلحات موضوعية: Adenocarcinoma, Antineoplastic Agent, BRCA2 Protein, Cell Line, Tumor, DNA Damage, Drug Discovery, Drug Synergism, Homologous Recombination, Human, Models, Molecular, Pancreatic Neoplasm, Phthalazine, Piperazine, Poly(ADP-ribose) Polymerase Inhibitor, Protein Interaction Map, Rad51 Recombinase, Small Molecule Librarie, Synthetic Lethal Mutations

وصف الملف: STAMPA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32037829; info:eu-repo/semantics/altIdentifier/wos/WOS:000526403900049; volume:63; issue:5; firstpage:2588; lastpage:2619; numberofpages:32; journal:JOURNAL OF MEDICINAL CHEMISTRY; http://hdl.handle.net/11585/781298Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85081944614

الإتاحة: https://doi.org/10.1021/acs.jmedchem.9b01526Test
http://hdl.handle.net/11585/781298Test

المؤلفون: Previtali V., Myers S. H., Poppi L., Wynne K., Casamassima I., Girotto S., Di Stefano G., Farabegoli F., Roberti M., Oliviero G., Cavalli A.

المساهمون: Previtali V., Myers S.H., Poppi L., Wynne K., Casamassima I., Girotto S., Di Stefano G., Farabegoli F., Roberti M., Oliviero G., Cavalli A.

مصطلحات موضوعية: DNA repair, Homologous recombination, RAD51, RAD51/BRCA2 disruptor, Synthetic lethality

وصف الملف: STAMPA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37536521; info:eu-repo/semantics/altIdentifier/wos/WOS:001053059000001; volume:288; firstpage:1; lastpage:11; numberofpages:11; journal:JOURNAL OF PROTEOMICS; https://hdl.handle.net/11585/962463Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85166646625

الإتاحة: https://doi.org/10.1016/j.jprot.2023.104983Test
https://hdl.handle.net/11585/962463Test

المؤلفون: Nagtegaal, A.P. (Paul), Broer, L. (Linda), Zilhao, N.R. (Nuno R.), Jakobsdottir, M. (Margret), Bishop, C.E. (Charles E.), Brumat, M. (Marco), Christiansen, M.W. (Mark W.), Cocca, M. (Massimiliano), Gao, Y. (Yan), Heard-Costa, N.L. (Nancy L.), Evans, D.S. (Daniel), Pankratz, V.S. (Shane), Pratt, S.R. (Sheila R.), Price, T.R. (T Ryan), Spankovich, C. (Christopher), Stimson, M.R. (Mary R.), Valle, K. (Karen), Vuckovic, D. (Dragana), Wells, H. (Helena), Eiriksdottir, G. (Gudny), Fransen, E. (Erik), Ikram, M.A. (Arfan), Li, C.-M. (Chuang-Ming), Longstreth Jr, W.T., Steves, C.J. (Claire), Camp, G. (Guy) van, Correa, D.D., Cruickshanks, K.J. (Karen), Gasparini, P. (Paolo), Girotto, S., Deloukas, P. (Panagiotis), Nalls, M.A. (Michael), Schweinfurth, J.M. (John M.), Seshadri, S. (Sudha), Sotoodehnia, N. (Nona), Tranah, G.J. (Gregory), Uitterlinden, A.G. (André), Wilson, J.F. (James), Gudnason, V. (Vilmundur), Hoffman, H.J. (Howard J.), Williams, F.M. (Frances), Goedegebure, A. (Andre)

المصدر: Scientific Reports vol. 9 no. 1

وصف الملف: application/pdf

العلاقة: http://repub.eur.nl/pub/120696Test; urn:hdl:1765/120696

الإتاحة: https://doi.org/10.1038/s41598-019-51630-xTest
http://repub.eur.nl/pub/120696Test

المؤلفون: Demuro S., Sauvey C., Tripathi S. K., Di Martino R. M. C., Shi D., Ortega J. A., Russo D., Balboni B., Giabbai B., Storici P., Girotto S., Abagyan R., Cavalli A.

المساهمون: Demuro, S., Sauvey, C., Tripathi, S. K., Di Martino, R. M. C., Shi, D., Ortega, J. A., Russo, D., Balboni, B., Giabbai, B., Storici, P., Girotto, S., Abagyan, R., Cavalli, A.

مصطلحات موضوعية: Central nervous system, Docking studie, Enzymatic and cell-based assay, Kinase inhibitor, Multitarget compound, Selectivity, Tau phosphorylation assay, Tauopathie, X-ray studies

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34959172; info:eu-repo/semantics/altIdentifier/wos/WOS:000769400900012; volume:229; firstpage:114054; journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY; https://hdl.handle.net/11579/152460Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85121740861

الإتاحة: https://doi.org/10.1016/j.ejmech.2021.114054Test
https://hdl.handle.net/11579/152460Test