المؤلفون: Mohamed Reda Fazazi, Gian Filippo Ruda, Paul E. Brennan, Manu Rangachari

المصدر: Brain Research Bulletin, Vol 202, Iss , Pp 110748- (2023)

مصطلحات موضوعية: Sex differences, KDM5c, KDM6A, Th17 cell, Multiple sclerosis, Experimental autoimmune encephalomyelitis, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S0361923023001739Test; https://doaj.org/toc/1873-2747Test

الوصول الحر: https://doaj.org/article/a08035167d2f4dd9ac07786f36431026Test

المؤلفون: Srikannathasan Velupillai, Laura Díaz Sáez, Tobias Krojer, James Bennett, Gian Filippo Ruda, Tamas Szommer, Verena Straub, Graciela Nunez Alonso, Paulina Siejka, Anthony Bradley, Romain Talon, Michael Fairhead, Jon Elkins, Nir London, John Spencer, Frank von Delft, Oleg Fedorov, Paul Brennan, Kilian Huber

مصطلحات موضوعية: Uncategorised value

العلاقة: 10779/uos.23472680.v1; https://figshare.com/articles/journal_contribution/Human_peroxisomal_coenzyme_A_diphosphatase_NUDT7_a_target_enabling_package_TEP_/23472680Test

الإتاحة: https://figshare.com/articles/journal_contribution/Human_peroxisomal_coenzyme_A_diphosphatase_NUDT7_a_target_enabling_package_TEP_/23472680Test

المؤلفون: Laiyin Nie, S.R. Bushell, Victoria Cole, Paul Brennan, Tiago Moreira, A. Quigley, Gian Filippo Ruda, Leela Shrestha, James D. Love, Tomas C. Pascoa, N.A. Burgess-Brown, Shubhashish M.M. Mukhopadhyay, Elisabeth P. Carpenter, A. Chu, Ashley C. W. Pike, David Speedman

المصدر: Nat Struct Mol Biol

مصطلحات موضوعية: Models, Molecular, Spectrometry, Mass, Electrospray Ionization, Fatty Acid Elongases, Protein Conformation, Plasma protein binding, Crystallography, X-Ray, Article, Substrate Specificity, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Structural Biology, Catalytic Domain, Sf9 Cells, medicine, Animals, Humans, Coenzyme A, Histidine, Cloning, Molecular, Adrenoleukodystrophy, Molecular Biology, 030304 developmental biology, 0303 health sciences, Binding Sites, biology, Chemistry, Fatty Acids, Imidazoles, Active site, medicine.disease, Sphingolipid, Recombinant Proteins, Transmembrane protein, 3. Good health, HEK293 Cells, Biochemistry, biology.protein, Fatty acid elongation, 030217 neurology & neurosurgery, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb0907c639374e2c6daac672f563b845Test
https://doi.org/10.1038/s41594-021-00605-6Test

المؤلفون: Gian Filippo Ruda, Victor M. Bolanos-Garcia, Natalie L. Curtis, Paul Brennan

المصدر: Annual Review of Cancer Biology. 4:257-278

مصطلحات موضوعية: 0301 basic medicine, Genome instability, Cancer Research, Cell signaling, Cell division, Cancer, Cell Biology, Biology, medicine.disease, Cell biology, Chromosome segregation, 03 medical and health sciences, Spindle checkpoint, 030104 developmental biology, 0302 clinical medicine, Oncology, Mitotic spindle assembly checkpoint, 030220 oncology & carcinogenesis, medicine, Oncovirus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::30b1406e1378715cfa2fb8102e4d8122Test
https://doi.org/10.1146/annurev-cancerbio-030419-033541Test

المؤلفون: Paul Brennan, James D. Love, Leela Shrestha, Laiyin Nie, Gian Filippo Ruda, Tomas C. Pascoa, Shubhashish M.M. Mukhopadhyay, A. Chu, A. Quigley, Victoria Cole, Tiago Moreira, S.R. Bushell, Elisabeth P. Carpenter, N.A. Burgess-Brown, Ashley C. W. Pike, David Speedman

مصطلحات موضوعية: biology, Chemistry, Active site, medicine.disease, Sphingolipid, Transmembrane protein, Biochemistry, medicine, biology.protein, Fatty acid elongation, Adrenoleukodystrophy, Binding site, Function (biology), Histidine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::7454b44666c6c5228050e372073713a1Test
https://doi.org/10.1101/2020.11.11.378570Test

المؤلفون: Elisabeth Carpenter, Laiyin Nie, Ashley Pike, Tomas Pascoa, Gian Filippo Ruda, Amy Chu, Victoria Cole, Simon Bushell, Andrew Quigley, David Speedman, Tiago Moreira, Shubhashish Mukhopadhyay, Nicola Burgess-Brown, James Love, Paul Brennan

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::5b3f5060ba78dc7e5e5fcbfeaf41a58cTest
https://doi.org/10.21203/rs.3.rs-96918/v1Test

المؤلفون: Conor McClenaghan, Alexandra Mackenzie, Y.Y. Dong, N.A. Burgess-Brown, A. Quigley, Gian Filippo Ruda, Lishuang Cao, Michael V. Clausen, L. Dong, Prafulla Aryal, S. Goubin, Stephen J. Tucker, Shubhashish M.M. Mukhopadhyay, Mark S.P. Sansom, Elisabeth P. Carpenter, Mariana Grieben, Ashley C. W. Pike, Paul Brennan

مصطلحات موضوعية: Models, Molecular, Protein Folding, Protein Conformation, Stereochemistry, Serotonin reuptake inhibitor, Molecular Sequence Data, Gating, Molecular Dynamics Simulation, Crystallography, X-Ray, Protein Structure, Secondary, Article, 03 medical and health sciences, Potassium Channels, Tandem Pore Domain, 0302 clinical medicine, Protein structure, Fluoxetine, medicine, Humans, Amino Acid Sequence, Binding site, 030304 developmental biology, K2p channel, 0303 health sciences, Arachidonic Acid, Binding Sites, Multidisciplinary, Chemistry, Protein Structure, Tertiary, 3. Good health, Transport protein, Potassium, Biophysics, Protein folding, human activities, Ion Channel Gating, 030217 neurology & neurosurgery, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff00a48d4ce518c6ebb694b50186d46Test
https://doi.org/10.1126/science.1261512Test

المؤلفون: Andrea Armirotti, Gian Filippo Ruda, Giampiero Colombano, Andrea Cavalli, Cataldo Martucci, Tiziano Bandiera, Rita Scarpelli, Rosalia Bertorelli, Giuliana Ottonello, Sine Mandrup Bertozzi, Federico Falchi, Claudio Fiorelli

المساهمون: Falchi, Federico, Bertozzi, Sine Mandrup, Ottonello, Giuliana, Ruda, Gian Filippo, Colombano, Giampiero, Fiorelli, Claudio, Martucci, Cataldo, Bertorelli, Rosalia, Scarpelli, Rita, Cavalli, Andrea, Bandiera, Tiziano, Armirotti, Andrea

المصدر: Analytical Chemistry. 88:9510-9517

مصطلحات موضوعية: 0301 basic medicine, Principal Component Analysis, Chromatography, Chemistry, 010401 analytical chemistry, Mode (statistics), Regression analysis, 01 natural sciences, 0104 chemical sciences, Analytical Chemistry, Data set, 03 medical and health sciences, 030104 developmental biology, Models, Chemical, Molecular descriptor, Test set, Kernel (statistics), Partial least squares regression, Principal component analysis, Least-Squares Analysis, Biological system, Algorithms, Chromatography, Liquid

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1db07aa2ff8e42204db66bfcc6876bTest
https://doi.org/10.1021/acs.analchem.6b02075Test

المؤلفون: Alexander N. Plotnikov, Haim Barr, S. Velupillai, T. Krojer, Jingxu Guo, Jinrui Gan, Huib Ovaa, Oleg Fedorov, Christopher G. Dowson, Gian Filippo Ruda, R. Sethi, Chu Wang, Michael Fairhead, Ronen Gabizon, Nava Reznik, Gabriel Amitai, Daniel Zaidman, T. Szommer, James Bennett, Dom Bellini, Nir London, Paul P. Geurink, Efrat Resnick, Anthony Aimon, Verena M. Straub, Anthony R. Bradley, Frank von Delft, Y. Zhang, Alun R. Coker, Alice Douangamath, Laura Diaz Saez, Paul Brennan, Kilian Huber, Jin Gan

المصدر: Journal of the American Chemical Society, 141(22), 8951-8968
Journal of the American Chemical Society, 141(22), 8951-8968. AMER CHEMICAL SOC

مصطلحات موضوعية: Models, Molecular, Time Factors, Protein Conformation, Drug Evaluation, Preclinical, Electrons, Ligands, 010402 general chemistry, 01 natural sciences, Biochemistry, Catalysis, Deubiquitinating enzyme, chemistry.chemical_compound, Colloid and Surface Chemistry, Protein structure, Humans, QC, chemistry.chemical_classification, Pyrophosphatase, biology, Chemistry, HEK 293 cells, General Chemistry, Combinatorial chemistry, QP, 0104 chemical sciences, 3. Good health, Molecular Weight, HEK293 Cells, Enzyme, Covalent bond, Electrophile, biology.protein, Selectivity

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc5c370637dd62cafe589b277a9c578Test
http://wrap.warwick.ac.uk/119286/1/WRAP-rapid-covalent-probe-discovery-electrophile-fragment-screening-Dowson-2019.pdfTest

المؤلفون: R. Sethi, Alun R. Coker, Laura Diaz Saez, Paul Brennan, Kilian Huber, Huib Ovaa, Alexander N. Plotnikov, Gian Filippo Ruda, Dom Bellini, James Bennett, Michael Fairhead, rikannathasan Velupillai, Daniel Zaidman, Frank von Delft, Anthony R. Bradley, Nava Reznik, Haim Barr, T. Szommer, Jingxu Guo, Paul P. Geurink, Nir London, Alice Douangamath, Jinrui Gan, Gabriel Amitai, Anthony Aimon, Efrat Resnick, Verena M. Straub, T. Krojer, Oleg Fedorov, Christopher G. Dowson

مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, Pyrophosphatase, biology, 010405 organic chemistry, Chemistry, Ligand (biochemistry), 01 natural sciences, Combinatorial chemistry, 0104 chemical sciences, Deubiquitinating enzyme, 03 medical and health sciences, chemistry.chemical_compound, Enzyme, Fragment (logic), Covalent bond, Electrophile, biology.protein, Selectivity, 030304 developmental biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2e3f5bc3e57d245c704b16130f4040Test