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المؤلفون: Aalt Bast, Ger M.J. Janssen, Philippe Vangrieken, Ulrike von Rango, Salwan Al-Nasiry, Daan Vroomans, Frederik J. van Schooten, Alexander Remels, Yannick C W Pinckers, Paul M. H. Schiffers
المساهمون: RS: NUTRIM - R3 - Respiratory & Age-related Health, Farmacologie en Toxicologie, Obstetrie & Gynaecologie, MUMC+: MA Medische Staf Obstetrie Gynaecologie (9), RS: GROW - R4 - Reproductive and Perinatal Medicine, FSE Campus Venlo, RS: FSE UCV Adaptive responses in relation to health effect and safety of nutrition, Anatomie & Embryologie, RS: Carim - V02 Hypertension and target organ damage
المصدر: Hypertension Research, 43(12), 1361-1374. Nature Publishing Group
مصطلحات موضوعية: Vascular smooth muscle, Physiology, Placenta, 030204 cardiovascular system & hematology, medicine.disease_cause, 0302 clinical medicine, Pre-Eclampsia, Pregnancy, 030212 general & internal medicine, OXIDATIVE STRESS, Hypoxia, VITAMIN-E, Electrical impedance myography, Chemistry, WOMEN, Endothelial stem cell, medicine.anatomical_structure, Hypertension, embryonic structures, Female, medicine.symptom, Cardiology and Cardiovascular Medicine, medicine.medical_specialty, Endothelium, HYPERTENSIVE PREGNANCY, PATHOPHYSIOLOGY, In Vitro Techniques, Permeability, Cell Line, Preeclampsia, 03 medical and health sciences, Internal medicine, Internal Medicine, medicine, Humans, Placental hypoxia, UTERINE PERFUSION, Endothelial Cells, Hypoxia (medical), ANTIANGIOGENIC FACTORS, medicine.disease, DYSFUNCTION, Endocrinology, Vasoconstriction, 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid, Culture Media, Conditioned, CELLS, Endothelium, Vascular, Reactive Oxygen Species, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edbcd2a18f25bfd6ed5fbe02b594e336Test
https://doi.org/10.1038/s41440-020-0528-8Test -
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المؤلفون: Yiwen Liu, Nora Franceschini, Matej Durik, Oscar H. Franco, Paula K. Bautista Nino, Abbas Dehghan, Mohsen Ghanbari, A.H. Jan Danser, Jan H.J. Hoeijmakers, Catherine M. Shanahan, René de Vries, Marcel E Meima, Maryam Kavousi, Anton J.M. Roks, Usha M. Musterd-Bhaggoe, Ger M.J. Janssen, Christopher J. O'Donnell, Jo G. R. De Mey
المساهمون: RS: CARIM - R2 - Cardiac function and failure, RS: CARIM - R3 - Vascular biology, Farmacologie en Toxicologie, Pharmacology and Personalised Medicine, Genetica & Celbiologie, Moleculaire Genetica, Epidemiology, Internal Medicine, Molecular Genetics
المصدر: Niño, P K B, Durik, M, Danser, A H J, de Vries, R, Musterd-Bhaggoe, U M, Meima, M E, Kavousi, M, Ghanbari, M, Hoeijmakers, J H, O'Donnell, C J, Franceschini, N, Janssen, G M J, De Mey, J G R, Liu, Y, Shanahan, C M, Franco, O H, Dehghan, A & Roks, A J M 2015, ' Phosphodiesterase 1 regulation is a key mechanism in vascular aging ', Clinical Science, vol. 129, no. 12, pp. 1061-1075 . https://doi.org/10.1042/CS20140753Test
Clinical Science (London, England : 1979)
Clinical Science, 129(12), 1061-1075. Portland Press Ltd.
Clinical Science, 129(12), 1061-1075. Portland Press, Ltd.مصطلحات موضوعية: Carotid Artery Diseases, Aging, Vascular smooth muscle, genetic association, Vasodilator Agents, Blood Pressure, Vasodilation, PDE1, Carotid Intima-Media Thickness, Second Messenger Systems, Muscle, Smooth, Vascular, chemistry.chemical_compound, vascular smooth muscle cells, Cyclic GMP, Cells, Cultured, Cellular Senescence, Mice, Knockout, education.field_of_study, Hydrolysis, Phosphodiesterase, vascular disease, General Medicine, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Carotid Arteries, Phenotype, Hypertension, cyclic nucleotide phosphodiesterase, cardiovascular system, Sodium nitroprusside, medicine.drug, Senescence, medicine.medical_specialty, intima–media thickening, extracellular matrix, Myocytes, Smooth Muscle, Population, In Vitro Techniques, Biology, Polymorphism, Single Nucleotide, Nitric oxide, SDG 3 - Good Health and Well-being, Commentaries, Internal medicine, medicine, Animals, Humans, Genetic Predisposition to Disease, phosphodiesterases, education, Cyclic Nucleotide Phosphodiesterases, Type 5, Hyperplasia, genome-wide association study, Dose-Response Relationship, Drug, Phosphodiesterase 5 Inhibitors, Cyclic Nucleotide Phosphodiesterases, Type 1, Endonucleases, Mice, Inbred C57BL, Endocrinology, chemistry, Commentary
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1aed35bb177ab207f4aad1aed0d5397Test
https://pure.eur.nl/en/publications/e8e5c74c-65e8-43ea-b723-ee8670b0f61eTest -
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المؤلفون: Ger M.J. Janssen, Philippe Vangrieken, Paul M. H. Schiffers, Misha F. Vrolijk, Guido R.M.M. Haenen, Ming Zhang
المساهمون: RS: NUTRIM - R3 - Respiratory & Age-related Health, Promovendi NTM, Farmacologie en Toxicologie, RS: CARIM - R3.02 - Hypertension and target organ damage, Ondersteunend personeel CD, RS: CARIM - R2.03 - ECM + Wnt signaling, RS: FSE UCV Adaptive responses in relation to health effect and safety of nutrition, FSE Campus Venlo
المصدر: European Journal of Integrative Medicine, 18, 18-22. Elsevier GmbH
مصطلحات موضوعية: 0301 basic medicine, TCM Formula, HERBAL MEDICINES, Traditional Chinese medicine, RATS, 03 medical and health sciences, 0302 clinical medicine, PAIR, Medicine, Ma Huang, COMBINATION, PERSPECTIVE, EPHEDRINE ALKALOIDS, Ephedrine, TRADITIONAL CHINESE MEDICINE, Traditional medicine, Toxicity, business.industry, Contractile response, technology, industry, and agriculture, food and beverages, EXTRACT, Human placenta, Clinical Practice, 030104 developmental biology, Complementary and alternative medicine, 030220 oncology & carcinogenesis, FORMULAS, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef8538666ae8d4f2a20b11069facb55Test
https://cris.maastrichtuniversity.nl/en/publications/fd5d228f-4006-4d9d-a192-4ac326bb6db7Test -
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المؤلفون: Bart Ides, Edwin C. M. Mariman, Elias S.J. Arnér, Philippe Vangrieken, Paul M. H. Schiffers, Aalt Bast, Irina Pader, Ger M.J. Janssen, Katarina Johansson, Guido R.M.M. Haenen, Mireille M.J.P.E. Sthijns, Freek G. Bouwman, Kristien J.A. Lemmens
المساهمون: RS: NUTRIM - R3 - Respiratory & Age-related Health, RS: NUTRIM - R3 - Chronic inflammatory disease and wasting, Farmacologie en Toxicologie, RS: CARIM - R3.02 - Hypertension and target organ damage, Promovendi NTM, Ondersteunend personeel NTM, RS: NUTRIM - HB/BW section A, RS: NUTRIM - R1 - Obesity, diabetes and cardiovascular health, RS: NUTRIM - R4 - Gene-environment interaction, RS: CARIM - R3.05 - Vascular remodeling in cardiovascular disease, RS: CARIM - R2.03 - ECM + Wnt signaling
المصدر: Biochimica et Biophysica Acta-general Subjects, 1861(5), 1177-1189. Elsevier Science
مصطلحات موضوعية: 0301 basic medicine, Antioxidant, medicine.medical_treatment, Rutin, NF-KAPPA-B, Biophysics, Pharmacology, medicine.disease_cause, Biochemistry, Umbilical vein, Nrf2, PATHWAY, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, FLAVANOL (-)-EPICATECHIN, medicine, GLUTATHIONE, Adaptation, Molecular Biology, FLUORESCENT-PROBES, chemistry.chemical_classification, Flavonoids, Reactive oxygen species, Endothelial function, Glutathione, KEAP1, DIETARY FLAVONOID QUERCETIN, DYSFUNCTION, 030104 developmental biology, GCLC, MEDIATED DILATION, chemistry, REACTIVE OXYGEN, 030217 neurology & neurosurgery, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c07a8e1657fa9d8220d79759035a6b3aTest
https://cris.maastrichtuniversity.nl/en/publications/c7418c7e-a3cd-47c6-bf18-26a7b03325c7Test -
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المؤلفون: Ger M.J. Janssen, Matthijs G. Compeer, J. G. R. De Mey
المصدر: British Journal of Pharmacology. 170:1199-1209
مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Vascular smooth muscle, Calcium channel, Cerebral arteries, Biology, Endothelin 1, medicine.anatomical_structure, Endocrinology, Internal medicine, medicine.artery, cardiovascular system, medicine, Basilar artery, medicine.symptom, Endothelin receptor, Mesenteric arteries, Vasoconstriction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::32224edc6027d9854e5d68e60944b8feTest
https://doi.org/10.1111/bph.12332Test -
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المؤلفون: Aalt Bast, Salwan Al-Nasiry, Marc E. A. Spaanderman, Ger M.J. Janssen, Antje R. Weseler, Philippe Vangrieken, Paul M. H. Schiffers
المساهمون: Promovendi NTM, Farmacologie en Toxicologie, RS: NUTRIM - R3 - Respiratory & Age-related Health, RS: GROW - R4 - Reproductive and Perinatal Medicine, Obstetrie & Gynaecologie, MUMC+: MA Medische Staf Obstetrie Gynaecologie (9), RS: CARIM - R2.03 - ECM + Wnt signaling, RS: CARIM - R3.02 - Hypertension and target organ damage
المصدر: PLOS ONE, 13(8):e0202648. Public Library of Science
PLoS ONE, Vol 13, Iss 8, p e0202648 (2018)مصطلحات موضوعية: 0301 basic medicine, Placenta, lcsh:Medicine, Constriction, Pathologic, 030204 cardiovascular system & hematology, OXYGEN, 0302 clinical medicine, Pre-Eclampsia, Pregnancy, ENDOTHELIN, Vasoconstrictor Agents, lcsh:Science, PREDICTORS, Hypoxia, Multidisciplinary, WOMEN, Chorion, Cell Hypoxia, PREECLAMPSIA, medicine.anatomical_structure, Female, medicine.symptom, Muscle Contraction, medicine.medical_specialty, Endothelium, Inflammation, NORMAL-PREGNANCY, MECHANISMS, Preeclampsia, Contractility, 03 medical and health sciences, Internal medicine, medicine, Humans, HYPERTENSION, business.industry, lcsh:R, EXTRACELLULAR VESICLES, Myography, Hypoxia (medical), medicine.disease, 030104 developmental biology, Endocrinology, Vasoconstriction, 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid, Culture Media, Conditioned, lcsh:Q, Endothelium, Vascular, INHIBITORS, business, Myograph
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b677a1f1282b5e8e044aa61f613e723Test
https://doi.org/10.1371/journal.pone.0202648Test -
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المؤلفون: Irina Pader, Mireille M.J.P.E. Sthijns, Paul M. H. Schiffers, A. Bast, Philippe Vangrieken, Kristien J.A. Lemmens, Guido R.M.M. Haenen, Elias S.J. Arnér, Ger M.J. Janssen, Freek G. Bouwman, Katarina Johansson, B. Ides, Edwin C. M. Mariman
المصدر: Toxicology Letters. 258:S124-S125
مصطلحات موضوعية: Rutin, chemistry.chemical_compound, chemistry, medicine, General Medicine, Endothelial dysfunction, Adaptation, Toxicology, medicine.disease, medicine.disease_cause, Oxidative stress, Cell biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::272fc308ae5f221577a5dcefe05e7ae5Test
https://doi.org/10.1016/j.toxlet.2016.06.1499Test -
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المساهمون: Farmacologie & Toxicologie, RS: CARIM School for Cardiovascular Diseases
المصدر: Journal of Pharmacology and Experimental Therapeutics, 333(1), 210-217. American Society for Pharmacology and Experimental Therapeutics
مصطلحات موضوعية: Male, medicine.medical_specialty, Indoles, Endothelium, Small-Conductance Calcium-Activated Potassium Channels, Muscle Relaxation, Receptors, Cytoplasmic and Nuclear, Rats, Inbred WKY, Muscle, Smooth, Vascular, Biological Factors, Potassium Channels, Calcium-Activated, chemistry.chemical_compound, Soluble Guanylyl Cyclase, SK3, Internal medicine, Oximes, medicine, Animals, Cyclooxygenase Inhibitors, Splanchnic Circulation, Mesenteric arteries, Pharmacology, Chemistry, Prostanoid, Blood flow, Intermediate-Conductance Calcium-Activated Potassium Channels, Acetylcholine, Potassium channel, Mesenteric Arteries, Rats, Endocrinology, medicine.anatomical_structure, Muscle relaxation, Guanylate Cyclase, Anesthesia, Molecular Medicine, Endothelium, Vascular, Stress, Mechanical, Nitric Oxide Synthase, Soluble guanylyl cyclase, Muscle Contraction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7281daf95ae7be6eddbd2f4b1d2a28aTest
https://doi.org/10.1124/jpet.109.161448Test -
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المؤلفون: J. G. R. De Mey, Ger M.J. Janssen, H.W.F. van Eijndhoven, Marc E. A. Spaanderman, Louis L. H. Peeters, Robert Aardenburg
المصدر: Journal of Vascular Research, 45, 350-6
Journal of Vascular Research, 45, 4, pp. 350-6مصطلحات موضوعية: medicine.medical_specialty, Health aging / healthy living [IGMD 5], Adrenergic receptor, Physiology, Calcitonin Gene-Related Peptide, Vasodilation, Calcitonin gene-related peptide, Biology, Adenylyl cyclase, chemistry.chemical_compound, Pregnancy, Internal medicine, medicine, Animals, Receptor, Mesenteric arteries, Forskolin, Cardiovascular diseases [NCEBP 14], Effective Hospital Care [EBP 2], Mesenteric Arteries, Rats, Human Reproduction [NCEBP 12], Endocrinology, medicine.anatomical_structure, chemistry, Doxycycline, Matrix Metalloproteinase 2, Female, Cardiology and Cardiovascular Medicine, Adenylyl Cyclases, Receptors, Calcitonin Gene-Related Peptide, Myograph
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::188b1490875fe916e18e0a24a039bedfTest
https://doi.org/10.1159/000119754Test -
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المؤلفون: Carlos E. Blanco, Jo G. R. De Mey, Gregorio E. Fazzi, Ger M.J. Janssen, Marijke W. Sanders
المصدر: Hypertension. 46:71-75
مصطلحات موضوعية: Male, Aging, medicine.medical_specialty, Offspring, Renal function, Blood Pressure, Hematocrit, Kidney, urologic and male genital diseases, Renal Circulation, Internal medicine, Internal Medicine, Albuminuria, Animals, Medicine, Rats, Wistar, Fetal Growth Retardation, Dose-Response Relationship, Drug, medicine.diagnostic_test, business.industry, Sodium, Dietary, Blood flow, Rats, Filtration fraction, Blood pressure, Endocrinology, Animals, Newborn, Renal blood flow, Female, medicine.symptom, business, Glomerular Filtration Rate
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f199d18fea943767b7d6dff93aec6942Test
https://doi.org/10.1161/01.hyp.0000171475.40259.d1Test